Abstract:
BACKGROUND:After cervical spinal cord injury, current options for treatment of upper extremity motor functions have been limited to traditional approaches. However, there is a substantial need to explore more rigorous alternative treatments to facilitate motor recovery. OBJECTIVE:To demonstrate whether anodal-primary motor cortex (M1) excitability enhancement (with cathodal-supra orbital area) (atDCS) combined with robot-assisted arm training (R-AAT) will provide greater improvement in contralateral arm and hand motor functions compared to sham stimulation (stDCS) and R-AAT in patients with chronic, incomplete cervical spinal cord injury (iCSCI). METHODS:In this parallel-group, double-blinded, randomized and sham-controlled trial, nine participants with chronic iCSCI (AIS C and D level) were randomized to receive 10 sessions of atDCS or stDSC combined with R-AAT. Feasibility and tolerability was assessed with attrition rate and occurrence of adverse events, Changes in arm and hand function were assessed with Jebson Taylor Hand Function Test (JTHFT). Amount of Use Scale of Motor Activity Log (AOU-MAL), American Spinal Injury Association Upper Extremity Motor Score and Modified Ashworth Scale (MAS) at baseline, after treatment, and at two-month follow-up. RESULTS:None of the participants missed a treatment session or dropped-out due to adverse events related to the treatment protocol. Participants tended to perform better in JTHFT and AOU-MAL after treatment. Active group at post-treatment and two-month follow-up demonstrated better arm and hand performance compared to sham group. CONCLUSION:These preliminary findings support that modulating excitatory input of the corticospinal tracts on spinal circuits may be a promising strategy in improving arm and hand functions in persons with incomplete tetraplegia. Further study is needed to explore the underlying mechanisms of recovery.
journal_name
NeuroRehabilitationjournal_title
NeuroRehabilitationauthors
Yozbatiran N,Keser Z,Davis M,Stampas A,O'Malley MK,Cooper-Hay C,Frontera J,Fregni F,Francisco GEdoi
10.3233/NRE-161371subject
Has Abstractpub_date
2016-07-15 00:00:00pages
401-11issue
3eissn
1053-8135issn
1878-6448pii
NRE1371journal_volume
39pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:The aim of this study was to assess the effect of Kinesio Taping on body stability in subjects with MS. STUDY DESIGN:Non controlled intervention study in a Rehabilitation Unit. INTERVENTION:A consecutive convenience sample of 15 individuals with multiple sclerosis was assessed. Kinesio Tex Tape was applied ...
journal_title:NeuroRehabilitation
pub_type: 临床试验,杂志文章
doi:10.3233/NRE-2011-0665
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:Little is known about neural recovery of an injured cingulum following brain injury. We report on a patient with brain injury who showed apparent neural recovery of an injured cingulum on follow up diffusion tensor tractography (DTT). METHODS:A 53-year-old female patient had suffered hypoxic ischemic brain ...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
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abstract::Long-term outcome assessment of people with spinal cord injury (SCI) beyond acute rehabilitation is becoming an increasingly important issue as life expectancies for people with SCI approach those of the general population. This article provides information about research on the long-term physical and psychological we...
journal_title:NeuroRehabilitation
pub_type: 杂志文章
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journal_title:NeuroRehabilitation
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journal_title:NeuroRehabilitation
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pub_type: 杂志文章,随机对照试验
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journal_title:NeuroRehabilitation
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pub_type: 杂志文章,评审
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章,meta分析
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更新日期:2012-01-01 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-01 00:00:00
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更新日期:2010-01-01 00:00:00
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pub_type: 杂志文章
doi:10.3233/NRE-192850
更新日期:2019-01-01 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:10.3233/NRE-1997-9105
更新日期:1997-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:
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pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2017-01-01 00:00:00
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