Abstract：
PURPOSE:Surveillance for long-term complications related to previous cancer therapy can help diagnose/manage chronic health conditions in childhood cancer survivors and improve survivor quality of life. However, a challenge to delivering long-term care to childhood cancer survivors is loss to follow-up; many patients discontinue care at specialized survivor care centers. The purpose of this study was to examine patterns of loss to follow-up among a cohort of childhood cancer survivors. METHODS:This retrospective study examined follow-up patterns among a nonrandom representative sample of 370 childhood cancer survivors among 1116 patients from a single institution. The median age of patients at diagnosis was 10.2 years (range <1-21). Factors potentially related to follow-up were utilized to evaluate patterns of follow-up across 5-year intervals following completion of active therapy. The association between patient characteristics and follow-up was evaluated using univariate and multivariate binomial regression models. RESULTS:The probability of follow-up 1-5 years post-treatment was 91.2% (89.7%-92.5%) but dropped to 68.5% (66.2%-70.8%) during years 6-10, 47.7% (45.0%-50.3%) during years 11-15, and continued to steadily decrease over time. Overall, white race, diagnoses at younger ages, patients with lymphomas/leukemias, and decade of diagnosis were each associated with somewhat better rates of follow-up. CONCLUSIONS:These findings highlight the lack of follow-up by adult survivors of childhood cancer with only approximately one-half of patients returning for follow-up 10 years after completion of therapy. Interventions focused on educating both patients and primary care physicians may help to increase long-term follow-up care among this at-risk population.
journal_name
J Adolesc Young Adult Oncoljournal_title
Journal of adolescent and young adult oncologyauthors
Rokitka DA,Curtin C,Heffler JE,Zevon MA,Attwood K,Mahoney MCdoi
10.1089/jayao.2016.0023subject
Has Abstractpub_date
2017-03-01 00:00:00pages
67-73issue
1eissn
2156-5333issn
2156-535Xjournal_volume
6pub_type
杂志文章abstract：: Purpose: With an increasing focus on developing survivorship services tailored for adolescent and young adult (AYA) cancer survivors, incorporation of viewpoints from both survivors and health care professionals (HCPs) is important. This study aims to explore the perceptio...
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journal_title：Journal of adolescent and young adult oncology
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doi：10.1089/jayao.2015.0039
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journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章,随机对照试验
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abstract：:Radiation-induced phantosmia has been reported both in children and adults. A fraction of these patients have nausea and vomiting triggered by phantosmia. Radiation-induced phantosmia, although transient, can be distressing enough to prevent a patient from staying still during radiation therapy. To date, specific inte...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2019.0103
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abstract：PURPOSE:Adolescents with cancer have unique developmental considerations. These include brain development, particularly in the frontal lobe, and a focus on completing education and entering the workforce. Cancer and treatment at this stage may prove to uniquely affect survivors' experience of cognitive and occupational...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2017.0043
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abstract：:Childhood cancer survivors (CCS) are at increased risk of subsequent malignant neoplasms (SMNs). However, the impact of SMNs on long-term psychosocial functioning is unknown. In a cohort of 322 young adult CCS, survivors who developed a SMN (n = 43, 13.4%) did not report a significantly higher burden of fatigue, insom...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2020.0046
更新日期：2020-08-14 00:00:00
abstract：:Infertility is often an expected side effect of cancer treatment, although the idea of fertility and sterility may be difficult for the child or adolescent patient to comprehend. Several established fertility preservation options exist for males and females, such as cryopreservation of sperm or embryos. Experimental t...
journal_title：Journal of adolescent and young adult oncology
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doi：10.1089/jayao.2010.0003
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journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2019.0031
更新日期：2019-10-01 00:00:00
abstract：PURPOSE:As many as two-thirds of male childhood cancer survivors are at risk for fertility impairment as a consequence of treatment. Despite this, survivorship guidelines lack concrete recommendations as to when fertility status conversations should happen between patients and providers and what should be discussed. Th...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2018.0094
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abstract：: Background: The increase in breast cancer (BC) cases in young women is of great importance since the tumor behavior in this group is generally more aggressive than in their older counterparts, and strategies for early diagnosis and prognostication are needed. Therefore, th...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2020.0037
更新日期：2020-07-21 00:00:00
abstract：:This review explores the literature on experiences of young people (15-39 years) living with cancer from nonmetropolitan areas, given most available research has focused on those living in major metropolitan areas. The purpose of the review was to inform (a) clinical practice and (b) future research on young people li...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2019.0053
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abstract：:Hypogammaglobulinemia is a poorly described complication of chemotherapy in adolescents and young adults (AYAs, 15-39 years) with acute lymphoblastic leukemia (ALL). The majority of AYAs treated on a Berlin-Frankfurt-Munster-based ALL regimen experienced hypogammaglobulinemia (65.0% [13/20]). Febrile neutropenia episo...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2020.0060
更新日期：2020-12-01 00:00:00
abstract：:Based on an increased appreciation of the unique challenges facing adolescents and young adults with cancer, there has been a coordinated national effort in Australia in recent years to address this issue. In 2007, CanTeen, a consumer support organization for young people with cancer, partnered with the Australian fed...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2012.0032
更新日期：2013-09-01 00:00:00
abstract：PURPOSE:Young adult oncology has gained momentum in recognizing the unique medical and psychosocial needs of the population of adolescents and young adults with cancer (AYAC). However, many of their psychosocial needs remain unmet and we are yet to identify how clinical or research programs can be tailored to meet thes...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章,随机对照试验
doi：10.1089/jayao.2017.0101
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:Cancer is a significant health concern for adolescents and young adults (AYAs; aged 15-24 years). Monitoring population-level changes in incidence, mortality, and survival is complicated by the lack of published data presenting statistics separately for AYAs. This study synthesizes and reviews data on AYA cance...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2017.0095
更新日期：2018-06-01 00:00:00
abstract：:Many adolescent female cancer patients will survive into their reproductive years. Pediatric oncologists are advised to discuss oncofertility during treatment planning. In this pilot study, 19 adolescent females completed a retrospective survey assessing recall of a fertility discussion, satisfaction with fertility kn...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2017.0079
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:There is a growing interest in fertility preservation as emerging research is highlighting the prevalence of infertility among young cancer survivors and its negative impact on quality of life. Previous qualitative research has identified barriers of fertility preservation care among professionals. The aim of t...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2016.0087
更新日期：2017-09-01 00:00:00
abstract：: Purpose: Survivors of cancer diagnosed during adolescence and young adulthood (AYA; aged 15-39) may experience quality of life (QOL) limitations; however, little is known about QOL for AYA survivors who are now middle-aged or among racial/ethnic minority survivors. We eval...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2013.0035
更新日期：2014-06-01 00:00:00
abstract：: Background: Location of death (LOD) is an important aspect of end-of-life (EOL) care. Adolescents and young adults (YAs) with pediatric malignancies are increasingly treated in pediatric institutions. YAs, generally defined as 18-39 years old, deserve specific attention be...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2018.0123
更新日期：2019-08-01 00:00:00
abstract：: Purpose: Testicular germ cell tumors (TGCT) are the most common solid organ malignancy in young men. It is a largely curable disease, so the extent to which it affects quality of life-including male fertility-is important. Abnormal semen analysis is highly predictive of ma...
journal_title：Journal of adolescent and young adult oncology
pub_type： 评审
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更新日期：2014-12-01 00:00:00
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journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2012.0029
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journal_title：Journal of adolescent and young adult oncology
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doi：10.1089/jayao.2016.0048
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journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2017.0069
更新日期：2018-04-01 00:00:00
abstract：:The inclusion of asparaginase in chemotherapy regimens to treat acute lymphoblastic leukemia (ALL) has had a positive impact on survival in pediatric patients. Historically, asparaginase has been excluded from most treatment protocols for adolescent and young adult (AYA) patients because of perceived toxicity in this ...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章,评审
doi：10.1089/jayao.2015.0014
更新日期：2015-09-01 00:00:00
abstract：:Delayed diagnosis due to lack of education may contribute to lack of improvement in adolescent and young adult (AYA) cancer survival. This program sought to educate trainees and AYAs in the community. The "Learning, Education, Awareness, Prevention (L.E.A.P) Young Adult Cancer" outreach program was developed to teach ...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2017.0060
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:Photovoice is a novel and promising intervention for working with youth in healthcare settings. Despite this, few studies have examined the efficacy of photovoice as a clinical tool for working with teenagers who are on their cancer journey. To better understand the needs of teenagers with cancer and the ways t...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2017.0073
更新日期：2018-02-01 00:00:00
abstract：: Purpose: Most evidence for the relationship between physical activity, nutrition education, and late effects from cancer treatment come from cross-sectional studies. The purpose of this pilot study was to determine if 8 weeks of exercise and nutrition education in adolesce...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2020.0116
更新日期：2020-09-14 00:00:00
abstract：: Purpose: Childhood cancer survivors are at risk for impaired psychosocial functioning, but limited research has focused on psychosexual outcomes in young adulthood. This qualitative study examined the perceived impact of childhood cancer on adult survivors' romantic relati...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2019.0114
更新日期：2020-06-01 00:00:00
abstract：:Communication plays an essential role in social relationships. Yet it is unclear how young cancer patients and survivors communicate with peers, and whether this contributes to increased rates of social difficulties. We aimed to analyze how childhood cancer patients and survivors communicate about their cancer with fa...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2017.0131
更新日期：2018-10-01 00:00:00
abstract：:Adolescents and young adults (AYAs) with cancer represent a unique group with unmet needs. Metrics and quality indicators are important for evaluating AYA cancer care. The purpose of this study is to describe the quality indicators in a Canadian context that are used for AYA (15-39 years of age) cancer care and contro...
journal_title：Journal of adolescent and young adult oncology
pub_type： 杂志文章
doi：10.1089/jayao.2019.0069
更新日期：2020-02-01 00:00:00
