Informed Consent in Health Research: Challenges and Barriers in Low-and Middle-Income Countries with Specific Reference to Nepal.

abstract：BACKGROUND:This article describes the types of community-wide benefits provided by investigators conducting public health research in South Asia as well as their self-reported reasons for providing such benefits. METHODS:We conducted 52 in-depth interviews to explore how public health investigators in low-resource set...

journal_title：Developing world bioethics

authors： Taylor HA,Merritt MW

更新日期：2012-12-01 00:00:00

abstract：:The significance of animals in research cannot be over-emphasized. The use of animals for research and training in research centres, hospitals and schools is progressively increasing. Advances in biotechnology to improve animal productivity require animal research. Drugs being developed and new interventions or therap...

journal_title：Developing world bioethics

authors： Seth M,Saguti F

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Explaining technical terms in consent forms prior to seeking informed consent to recruit into trials can be challenging in developing countries, and more so when the studies are randomized controlled trials. This study was carried out to examine the opinions of researchers on ways of dealing with these chall...

journal_title：Developing world bioethics

authors： Newton SK,Appiah-Poku J

更新日期：2007-12-01 00:00:00

abstract：:In this paper, we describe the potential role laypersons on ethics committees can play in ensuring community concerns are addressed in the design and implementation of genomic research. We draw inferences from the outcome of an empirical study of the impact of training of laypersons to address community engagement iss...

journal_title：Developing world bioethics

authors： Folayan MO,Oyedeji KS,Fatusi OA

更新日期：2015-04-01 00:00:00

abstract：:Given its intimate relationship with the human body and its environment, biotechnology innovation, and more particularly stem cell research innovations as a part thereof, implicate diverse social and moral/ethical issues. This paper explores some of the most important and controversial moral concerns raised by human e...

journal_title：Developing world bioethics

authors： Harmon SH

更新日期：2008-08-01 00:00:00

abstract：:The principle of informed refusal poses a specific problem when it is invoked by a pregnant woman who, in spite of having accepted her pregnancy, refuses the diagnostic and/or therapeutic measures that would ensure the well-being of her endangered fetus. Guidelines issued by professional bodies in the developed world ...

journal_title：Developing world bioethics

authors： van Bogaert LJ

更新日期：2006-03-01 00:00:00

abstract：:Inequities in global health are increasingly of interest to health care providers in developed countries. In response, many academic healthcare programs have begun to offer international service learning programs. Participants in these programs are motivated by ethical principles, but this type of work presents signif...

journal_title：Developing world bioethics

authors： Reisch RA

更新日期：2011-08-01 00:00:00

abstract：:Research ethics training during post-graduate education is necessary to improve ethical standards in the design and conduct of biomedical research. We studied quality and quantity of research ethics training in the curricula of post-graduate programs in the medical science in I.R. Iran. We evaluated curricula of 125 p...

journal_title：Developing world bioethics

authors： Nikravanfard N,Khorasanizadeh F,Zendehdel K

更新日期：2017-08-01 00:00:00

abstract：:Compared with data that is initially collected for research purposes, the mandatory authorization of a government database for secondary use deserves greater scrutiny because it consists of information that is collected initially for administrative purposes. Using the case of Taiwan's National Health Insurance (NHI) D...

journal_title：Developing world bioethics

authors： Yeh MJ

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:The globalization of clinical research in the last two decades has led to a significant increase in the volume of clinical research in developing countries. As of 2016, Uganda was the third largest destination for clinical trials in Africa. This requires adequate capacity and systems to facilitate ethical pr...

journal_title：Developing world bioethics

authors： Ochieng J,Mwaka E,Kwagala B,Sewankambo N

更新日期：2020-03-01 00:00:00

abstract：:Like other so-called 'parallel' practices in medicine, traditional medicine (TM) does not avoid criticism or even rejection. Nyika's article 'Ethical and Regulatory Issues Surrounding African Traditional Medicine in the Context of HIV/AIDS' looks at some of the issues from a traditional Western ethical perspective and...

journal_title：Developing world bioethics

authors： van Bogaert DK

更新日期：2007-04-01 00:00:00

abstract：:Unlike other countries in South Asia, in Nepal research in the health sector has a relatively recent history. Most health research activities in the country are sponsored by international collaborative assemblages of aid agencies and universities. Data from Nepal Health Research Council shows that, officially, 1,212 h...

journal_title：Developing world bioethics

authors： Sharma JR,Khatri R,Harper I

更新日期：2016-12-01 00:00:00

abstract：:I give an account how the principle of 'respect for autonomy' dominates the field of bioethics, and how it came to triumph over its competitors, 'respect for persons' and 'respect for free power of choice'. I argue that 'respect for autonomy' is unsatisfactory as a basic principle of bioethics because it is grounded i...

journal_title：Developing world bioethics

authors： Behrens KG

更新日期：2018-06-01 00:00:00

abstract：:This paper seeks to highlight the benefits of prioritizing moderate African communitarian principles as partly demonstrated in the HIV prevention strategies implemented in Uganda in the late 1980s. Pertinent lessons could be drawn so as to achieve the HIV prevention targets envisioned in the post-2015 development era....

journal_title：Developing world bioethics

authors： Wathuta J

更新日期：2018-06-01 00:00:00

abstract：:The impending implementation of pre-exposure prophylaxis (PrEP) has prompted complicated bioethical and public health ethics concerns regarding the moral distribution of antiretroviral medications (ARVs) to ostensibly healthy populations as a form of HIV prevention when millions of HIV-positive people still lack acces...

journal_title：Developing world bioethics

authors： Fiereck K

更新日期：2015-04-01 00:00:00

abstract：:Due to the financial pressure caused by cutbacks in funding and the race to achieve higher university rankings, researchers are competing for limited funds. These funds enable researchers to contribute to the scientific enterprise and to secure better positions. Given this pressure, there is a need to understand how a...

journal_title：Developing world bioethics

authors： Olesen AP,Amin L,Mahadi Z,Ibrahim M

更新日期：2020-11-10 00:00:00

abstract：:Psychiatric genetic research investigates the genetic basis of psychiatric disorders with the aim of more effectively understanding, treating, or, ultimately, preventing such disorders. Given the challenges of recruiting research participants into such studies, the potential for long-term benefits of such research, an...

journal_title：Developing world bioethics

authors： Palk AC,Bitta M,Kamaara E,Stein DJ,Singh I

更新日期：2020-09-01 00:00:00

abstract：:Stem cell tourism is a small but growing part of the thriving global medical tourism marketplace. Much stem cell research remains at the experimental stage, with clinical trials still uncommon. However, there are over 700 clinics estimated to be operating in mostly developing countries--from Costa Rica and Argentina t...

journal_title：Developing world bioethics

authors： Einsiedel EF,Adamson H

更新日期：2012-04-01 00:00:00

abstract：:The objective of this module is to cover ground that was not covered in-depth in any of the other modules, including: scientific misconduct, issues concerning the publication and ownership of research results (authorship guidelines - who is eligible to be considered an author, or contributor to a scientific paper etc....

journal_title：Developing world bioethics

authors： Schneider B,Schüklenk U

更新日期：2005-03-01 00:00:00

abstract：:Research is a global enterprise requiring participation of both genders for generalizable knowledge; advancement of science and evidence based medical treatment. Participation of women in research is necessary to reduce the current bias that most empirical evidence is obtained from studies with men to inform health ca...

journal_title：Developing world bioethics

authors： Princewill CW,Jegede AS,Nordström K,Lanre-Abass B,Elger BS

更新日期：2017-04-01 00:00:00

abstract：:Currently, health systems research (HSR) is reviewed by the same ethical standards as clinical research, which has recently been argued in the literature to be an inappropriate standard of evaluation. The issues unique to HSR warrant a different review by research ethics committees (RECs), as it does not impose the sa...

journal_title：Developing world bioethics

authors： Bachani AM,Rattani A,Hyder AA

更新日期：2016-12-01 00:00:00

abstract：:One effect of late capitalism--the commodification of practically everything--is to knock down the Chinese walls between the natural and productive realms, to use a Marxist framework. Women's labour in egg extraction and 'surrogate' motherhood might then be seen as what it is, labour which produces something of value....

journal_title：Developing world bioethics

authors： Dickenson D

更新日期：2002-05-01 00:00:00

abstract：:In the novel Racists by Kunal Basu (2006), two competing scientists initiate an experiment that they believe will prove which race is superior. The research subjects, one white and one black infant, are sequestered on an isolated island in the care of a mute nurse. The contest must be waged in a 'natural laboratory' w...

journal_title：Developing world bioethics

authors： Burns L,Lanoix M,Melnychuk RM,Pauly B

更新日期：2008-12-01 00:00:00

abstract：:The last 20 years have seen a staggering growth in the practice of off-shoring clinical research to low-and middle-income countries (LICs and MICs), a growth that has been matched by the neoliberal policies adopted by host countries towards attracting trials to their shores. A recurring concern in this context is the ...

journal_title：Developing world bioethics

authors： Mitra AG

更新日期：2013-12-01 00:00:00

abstract：:Four key guidance points in the UNAIDS guidance document, Ethical Considerations in HIV Preventive Vaccine Research, are compared with analogous statements in three other recently issued documents dealing with international research. Those documents are: the Declaration of Helsinki, as revised in 2000; the report of t...

journal_title：Developing world bioethics

authors： Macklin R

更新日期：2001-11-01 00:00:00

abstract：:The intensified nurse migration leads to severe problems for the health care systems in many developing countries. Using the Philippines as an example, this paper will address the question of global nurse migration from a philosophical perspective. John Rawls' liberal and Michael Walzer's communitarian theory of justi...

journal_title：Developing world bioethics

authors： Kaelin L

更新日期：2011-04-01 00:00:00

abstract：:Kidney transplantation is a lifesaving medical treatment. However, very high demand for kidneys with low kidney donation causes a black market that exploits patients' desperation and donors' vulnerability. The current kidney donation programs fail to produce promising results to avoid illegal and unethical kidney traf...

journal_title：Developing world bioethics

authors： Avci E

更新日期：2018-09-01 00:00:00

abstract：:The Ebola epidemic in Western Africa has highlighted issues related to weak health systems, the politics of drug and vaccine development and the need for transparent and ethical criteria for use of scarce local and global resources during public health emergency. In this paper we explore two key themes. First, we argu...

journal_title：Developing world bioethics

authors： Satalkar P,Elger BE,Shaw DM

更新日期：2015-08-01 00:00:00

abstract：:Many countries in Africa, and more generally those in the Global South with tropical areas, are plagued by illnesses that the wealthier parts of the world (mainly 'the West') neither suffer from nor put systematic effort into preventing, treating or curing. What does an ethic with a recognizably African pedigree entai...

journal_title：Developing world bioethics

authors： Metz T

更新日期：2018-09-01 00:00:00

abstract：:In the context of clinical and non-clinical biomedical practices, negligence is usually understood as a lapse of a specific professional duty by a healthcare worker or by a medical facility. This paper tries to delineate systemic negligence as another kind of negligence in the context of health systems, particularly i...

journal_title：Developing world bioethics

authors： Chakraborti C

更新日期：2015-12-01 00:00:00