Abstract:
:This study described the results of environmental enterovirus surveillance conducted in Shandong Province of China in 2013. Altogether 39 sewage samples were collected and 873 enterovirus isolates (including 334 polioviruses) belonging to 22 serotypes were obtained. Echovirus (E) -7, coxsackievirus (CV) -B5, E-11, E-6, and E-3 were the most commonly detected non-polio enterovirus serotypes, and phylogeny of E-7 and CV-B5 was described. The numbers of isolates of different serotypes from sewage supernatant were compared with those from the solids. Interestingly, dramatic divergence was observed between the supernatant and solids origin for the serotypes of E-3 and E-6, which were prone to the solids and supernatant, respectively. A following adsorption test with E-3 and E-6 added sewage specimens confirmed the different preference. Furthermore, the adsorption of Sabin poliovirus type 1 to the solids under different conditions was investigated, and the results showed that acid medium, cold temperature, and high solids concentration facilitated the viral adsorption to the solids, whereas change of virus titer did not influence the proportion of adsorption. These results highlighted the importance of combining the enterovirus isolates from the supernatant and solids together in environmental surveillance so as to better understand the local circulation of different serotypes.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Tao Z,Wang Z,Lin X,Wang S,Wang H,Yoshida H,Xu A,Song Ydoi
10.1038/srep31474subject
Has Abstractpub_date
2016-08-11 00:00:00pages
31474issn
2045-2322pii
srep31474journal_volume
6pub_type
杂志文章abstract::Inflammation is considered as a major contributor to brain injury following cerebral ischemia. The therapeutic potential of both MLC601/MLC901, which are herbal extract preparations derived from Chinese Medicine, has been reported both in advanced stroke clinical trials and also in animal and cellular models. The aim ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36138-0
更新日期:2018-12-24 00:00:00
abstract::High altitude pulmonary edema (HAPE) susceptibility is associated with EGLN1 polymorphisms, we hypothesized that HAPE-susceptible (HAPE-S, had HAPE episode in past) subjects may exhibit abnormal HIF1α levels in normoxic conditions. We measured HIF1α levels in HAPE-S and HAPE resistant (HAPE-R, no HAPE episode) individ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26468
更新日期:2016-05-23 00:00:00
abstract::Phaeocystis globosa, one of the most typical red tide-forming species, is usually mixed in the food composition of rotifers. To explore how rotifers respond by adjusting life history strategy when feeding on different quality foods, we exposed the rotifer Brachionus plicatilis to cultures with 100% Chlorella, a mixtur...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15863-y
更新日期:2017-11-13 00:00:00
abstract::Hepatocyte-specific HMGB1 deletion has been found to worsen the injury and inflammation in liver ischemia-reperfusion injury (IRI), highlighting a role for intracellular HMGB1 in cellular protection. Down-regulation of nuclear HMGB1 by small interfering RNA (siRNA) might not only decrease its injurious extracellular r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46272
更新日期:2017-04-06 00:00:00
abstract::The stochastic tunneling-basin hopping method (STUN-BH) was utilized to obtain the most stable peptide S7 configuration (Ac-Ser-Ser-Phe-Pro-Gln-Pro-Asn-CONH2) adsorbed on Au(111) facet. After the most stable S7 configuration was found, molecular dynamics (MD) simulation was conducted to investigate the thermal stabili...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59144-7
更新日期:2020-02-07 00:00:00
abstract::Epididymal Cysteine Rich Secretory Proteins 1 and 4 (CRISP1 and CRISP4) associate with sperm during maturation and play different roles in fertilization. However, males lacking each of these molecules individually are fertile, suggesting compensatory mechanisms between these homologous proteins. Based on this, in the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-35719-3
更新日期:2018-12-03 00:00:00
abstract::The distinction between primary and secondary volcaniclastic deposits, which are currently defined as the "direct" products of volcanic eruptions and the "reworked" products of the former, respectively, is the first step to interpreting volcaniclastic deposits, particularly the genetic connection with active volcanism...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48933-4
更新日期:2019-08-27 00:00:00
abstract::Treatment as Prevention (TasP) using directly-acting antivirals has been advocated for Hepatitis C Virus (HCV) in people who inject drugs (PWID), but treatment is expensive and TasP's effectiveness is uncertain. Previous modelling has assumed a homogeneously-mixed population or a static network lacking turnover in the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01862-6
更新日期:2017-05-12 00:00:00
abstract::Rett syndrome (RTT) is a neurodevelopmental disorder mainly caused by mutations in the gene encoding the transcriptional regulator Methyl-CpG-binding protein 2 (MeCP2), located on the X chromosome. Many RTT patients have breathing abnormalities, such as apnea and breathing irregularity, and respiratory infection is th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12293-8
更新日期:2017-09-20 00:00:00
abstract::Fermentation is the key process to produce the special color of congou black tea. The machine vision technology is applied to detect the color space changes of black tea's color in RGB, Lab and HSV, and to find out its relevance to black tea's fermentation quality. And then the color feature parameter is used as input...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28767-2
更新日期:2018-07-12 00:00:00
abstract::Assembly of metagenomic samples is a very complex process, with algorithms designed to address sequencing platform-specific issues, (read length, data volume, and/or community complexity), while also faced with genomes that differ greatly in nucleotide compositional biases and in abundance. To address these issues, we...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06480
更新日期:2014-10-01 00:00:00
abstract::Cell division during the reproductive phase of the Streptomyces life-cycle requires tight coordination between synchronous formation of multiple septa and DNA segregation. One remarkable difference with most other bacterial systems is that cell division in Streptomyces is positively controlled by the recruitment of Ft...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25782-1
更新日期:2018-05-09 00:00:00
abstract::Transport of self-propelled particles in a two-dimensional (2D) separate channel is investigated in the presence of the combined forces. By applying an ac force, the particles will be trapped by the separate walls. A dc force produces the asymmetry of the system and induces the longitudinal directed transport. Due to ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24001
更新日期:2016-04-01 00:00:00
abstract::Site-specific genome modification (SSM) is an important tool for mosquito functional genomics and comparative gene expression studies, which contribute to a better understanding of mosquito biology and are thus a key to finding new strategies to eliminate vector-borne diseases. Moreover, it allows for the creation of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43883
更新日期:2017-03-07 00:00:00
abstract::The aim of this study was to investigate rheumatoid arthritis (RA), and systemic lupus erythematous (SLE) as risk factors for stroke. The study was analyzed by Using the Taiwan Longitudinal Health Insurance Database 2005 (LHID2005), this cohort study investigated patients with a recorded diagnosis of RA (N = 6114), an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05110
更新日期:2014-06-05 00:00:00
abstract::In adipose tissue, agonists of the β3-adrenergic receptor (ADRB3) regulate lipolysis, lipid oxidation, and thermogenesis. The deficiency in the thermogenesis induced by neuroblast differentiation-associated protein AHNAK in white adipose tissue (WAT) of mice fed a high-fat diet suggests that AHNAK may stimulate energy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23426
更新日期:2016-03-18 00:00:00
abstract::Here we present a set of measurements using Differential Scanning Fluorimetry (DSF) as an inexpensive, high throughput screening method to investigate the folding of silk protein molecules as they abandon their first native melt conformation, dehydrate and denature into their final solid filament conformation. Our fir...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05625
更新日期:2014-07-09 00:00:00
abstract::Liquid extraction surface analysis mass spectrometry imaging (LESA-MSI) has been shown to be an effective tissue profiling and imaging technique, producing robust and reliable qualitative distribution images of an analyte or analytes in tissue sections. Here, we expand the use of LESA-MSI beyond qualitative analysis t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37648
更新日期:2016-11-24 00:00:00
abstract::Integrin alpha-4 (ITGA4) is a validated therapeutic target for multiple sclerosis (MS) and Natalizumab, an antibody targeting ITGA4 is currently approved for treating MS. However, there are severe side effects related to this therapy. In this study, we report the development of a novel DNAzyme that can efficiently cle...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01559-w
更新日期:2017-05-09 00:00:00
abstract::Atomoxetine is a norepinephrine reuptake inhibitor indicated in the treatment of attention-deficit/hyperactivity disorder. It is primarily metabolized by CYP2D6 to its equipotent metabolite, 4-hydroxyatomoxetine, which promptly undergoes further glucuronidation to an inactive 4-HAT-O-glucuronide. Clinical trials have ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30841-8
更新日期:2018-08-17 00:00:00
abstract::Conifer wood is an exceptionally stiff and strong material when its cellulose microfibrils are well aligned. However, it is not well understood how the polymer components cellulose, hemicelluloses and lignin co-operate to resist tensile stress in wood. From X-ray scattering, neutron scattering and spectroscopic data, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79676-2
更新日期:2021-01-11 00:00:00
abstract::Cancer patients often use dietary supplements while on therapy, but little is known about interactions of supplements with cancer chemotherapy. Black raspberries (BRB) have anti-cancer effects, but have not been evaluated for interference with chemotherapy for castrate-resistant prostate cancer (CRPC). Here we studied...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39589-1
更新日期:2019-03-13 00:00:00
abstract::Modulating the tumor microenvironment to promote an effective immune response is critical in managing any type of tumor. Melanoma is an aggressive skin cancer and the incidence rate is increasing worldwide. Potent protease inhibitors have recently been extensively researched as potential therapeutic agents against var...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52609-4
更新日期:2019-11-07 00:00:00
abstract::Melanocortin 4 receptor (MC4R) variants contribute to human obesity, and rats lacking functional MC4R (Mc4rK314X/K314X) are obese. We investigated the hypothesis that low energy expenditure (EE) and physical activity contribute to this obese phenotype in male rats, and determined whether lack of functional MC4R confer...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37435
更新日期:2016-11-25 00:00:00
abstract::The distribution of carbon from a branch setting pod in alfalfa was investigated during the seed development of seeds to determine the relative contribution of pod and leaf photoassimilates to the total C balance and to investigate the partitioning of these photoassimilates to other plant organs. A 13Clabeling procedu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42026
更新日期:2017-02-07 00:00:00
abstract::In situ HfB2-SiC-VSi2 composite was fabricated by reactive pressureless sintering at the temperature of 2150 °C for 4 h under a vacuum atmosphere. In situ SiC and VSi2 reinforcements were formed using VC and Si powders as starting materials according to the following reaction: VC + 3Si = SiC + VSi2. Microstructural st...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73295-7
更新日期:2020-10-06 00:00:00
abstract::Prolonged tomato consumption can mitigate ultraviolet (UV) light induced sunburn via unknown mechanisms. Dietary carotenoids distributed to skin are hypothesized to protect skin against UV-induced damage, although other phytochemicals may play a role. We hypothesize that tomato consumption would protect against skin c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05568-7
更新日期:2017-07-11 00:00:00
abstract::We investigated how skeletal muscle mass (SMM) affects spinal sagittal balance (radiographic parameters) in symptomatic spinal patients. The first purpose of this study was to evaluate the body composition and the spinal sagittal alignment in symptomatic spinal patients. The second purpose of this study was to compare...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33867-0
更新日期:2018-10-19 00:00:00
abstract::Human milk oligosaccharides (HMOs) play an important role in the health of an infant as substrate for beneficial gut bacteria. Little is known about the effects of HMO composition and its changes on the morbidity and growth outcomes of infants living in areas with high infection rates. Mother's HMO composition and inf...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40466
更新日期:2017-01-12 00:00:00
abstract::BiFeO3 is one of the most promising multiferroic materials but undergoes two major drawbacks: low dielectric susceptibility and high dielectric loss. Here we report high in-plane dielectric permittivity (ε' ∼2500) and low dielectric loss (tan δ < 0.01) obtained on Bi0.95Y0.05FeO3 films epitaxially grown on SrTiO3 (001...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25535
更新日期:2016-05-09 00:00:00