Optogenetic and chemogenetic strategies for sustained inhibition of pain.

abstract：:Voice disorder such as vocal fatigue is a common and complex multifaceted clinical problem that presents a significant impact on quality of life. In this study, the functional near-infrared diffuse optical technique (fNIRS-DOT) was proposed as a novel approach for human vocal cords oxidative metabolism detection and a...

journal_title：Scientific reports

authors： Lin TC,Chen JC,Liu CH,Lee CY,Tsou YA,Chuang CC

更新日期：2017-12-05 00:00:00

abstract：:Regret results from comparing non-optimal outcomes containing both gain and loss parts to better alternatives during decision-making. The present fMRI study aimed to explore whether levels of regret could change when gain or loss part of a non-optimal outcome was focused during a sequential risk taking task, i.e. the ...

journal_title：Scientific reports

authors： Liu Z,Li L,Zheng L,Xu M,Zhou FA,Guo X

更新日期：2017-02-01 00:00:00

abstract：:Wheat (Triticum aestivum), one of the world's most important crops, is facing unprecedented challenges due to global warming. To evaluate the gene resources for heat adaptation in hexaploid wheat, small heat shock proteins (sHSPs), the key plant heat protection genes, were comprehensively analysed in wheat and related...

journal_title：Scientific reports

authors： Wang X,Wang R,Ma C,Shi X,Liu Z,Wang Z,Sun Q,Cao J,Xu S

更新日期：2017-05-31 00:00:00

abstract：:Whether the stress-loading of faults to failure in earthquakes appears to be random or to an extent explainable, given constraints on fault/shear-zone interaction and the build-up and release of stress over many earthquake cycles, is a key question for seismic hazard assessment. Here we investigate earthquake recurren...

journal_title：Scientific reports

authors： Sgambato C,Faure Walker JP,Mildon ZK,Roberts GP

更新日期：2020-07-29 00:00:00

abstract：:The alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) is known to trigger the adaptive response by inducing the ada-regulon - consisting of three DNA repair enzymes Ada, AlkB, AlkA and the enigmatic AidB. We have applied custom designed tiling arrays to study transcriptional changes in Escherichia coli foll...

journal_title：Scientific reports

authors： Booth JA,Thomassen GO,Rowe AD,Weel-Sneve R,Lagesen K,Kristiansen KI,Bjørås M,Rognes T,Lindvall JM

更新日期：2013-10-25 00:00:00

abstract：:Molecular imaging technique is an attractive tool to detect liver disease at early stage. This study aims to develop a simultaneous dual-isotope single photon emission computed tomography (SPECT)/CT imaging method to assist diagnosis of hepatic tumor and liver fibrosis. Animal models of liver fibrosis and orthotopic h...

journal_title：Scientific reports

authors： Guo Z,Gao M,Zhang D,Li Y,Song M,Zhuang R,Su X,Chen G,Liu T,Liu P,Wu H,Du J,Zhang X

更新日期：2016-07-05 00:00:00

abstract：:The objective of this study was to evaluate the clinical ability of Near-Infrared Light-Transillumination (NILT) for approximal dentinal caries detection and to compare with direct digital-radiography (DDR), as well as to determine whether the combination of both techniques improves the diagnostic capacity of the lesi...

journal_title：Scientific reports

authors： Melo M,Pascual A,Camps I,Ata-Ali F,Ata-Ali J

更新日期：2019-10-02 00:00:00

abstract：:Morality and empathy are both crucial in building human society. Yet the relationship between them has been merely explored. The present study revealed how the morality influenced empathy for pain by comparing the ERPs elicited by pictures showing the targets' in pain primed by different moral information about the ta...

journal_title：Scientific reports

authors： Cui F,Ma N,Luo YJ

更新日期：2016-02-11 00:00:00

abstract：:Risk stratification is crucial in prevention. Circulating microRNAs have been proposed as biomarkers in cardiovascular disease. Here a miR panel consisting of miRs related to different cardiovascular pathophysiologies, was evaluated to predict outcome in the context of prevention. MiR-34a, miR-223, miR-378, miR-499 an...

journal_title：Scientific reports

authors： Keller T,Boeckel JN,Groß S,Klotsche J,Palapies L,Leistner D,Pieper L,Stalla GK,Lehnert H,Silber S,Pittrow D,Maerz W,Dörr M,Wittchen HU,Baumeister SE,Völker U,Felix SB,Dimmeler S,Zeiher AM

更新日期：2017-07-03 00:00:00

abstract：:We investigated if fermentation with probiotic cultures could improve the production of health-promoting biological compounds in Astragalus membranaceus. We tested the probiotics Enterococcus faecium, Lactobacillus plantarum and Enterococcus faecium + Lactobacillus plantarum and applied PacBio single molecule, real-ti...

journal_title：Scientific reports

authors： Qiao H,Zhang X,Shi H,Song Y,Bian C,Guo A

更新日期：2018-08-08 00:00:00

abstract：:In the present study, a coarse grained AZ31 plate was refined by twin boundaries (TBs) and grain boundaries (GBs), respectively. A comparative study about the different effects of grain refinements by GBs and by TBs on tension-compression yield asymmetry was performed. Our results show that both the refinements by GBs...

journal_title：Scientific reports

authors： Yu H,Xin Y,Chapuis A,Huang X,Xin R,Liu Q

更新日期：2016-07-04 00:00:00

abstract：:We construct two families of orthogonal product quantum states that cannot be exactly distinguished by local operation and classical communication (LOCC) in the quantum system of (2k+i) ⊗ (2l+j) (i, j ∈ {0, 1} and i ≥ j ) and (3k+i) ⊗ (3l+j) (i, j ∈ {0, 1, 2}). And we also give the tiling structure of these two famili...

journal_title：Scientific reports

authors： Zhang X,Tan X,Weng J,Li Y

更新日期：2016-07-05 00:00:00

abstract：:P130CAS/BCAR1 belongs to the CAS family of adaptor proteins, with important regulatory roles in cell migration, cell cycle control, and apoptosis. Previously, we and others showed that P130CAS mediates VEGF-A and PDGF signalling in vitro, but its cardiovascular function in vivo remains relatively unexplored. We charac...

journal_title：Scientific reports

authors： Wisniewski L,French V,Lockwood N,Valdivia LE,Frankel P

更新日期：2020-09-24 00:00:00

abstract：:A new extraordinary application of deoxyribonucleic acid (DNA) thin-solid-film was experimentally explored in the field of ultrafast nonlinear photonics. Optical transmission was investigated in both linear and nonlinear regimes for two types of DNA thin-solid-films made from DNA in aqueous solution and DNA-cetyltrime...

journal_title：Scientific reports

authors： Khazaeinezhad R,Hosseinzadeh Kassani S,Paulson B,Jeong H,Gwak J,Rotermund F,Yeom DI,Oh K

更新日期：2017-01-27 00:00:00

abstract：:Inhibition of return (IOR), typically explored in cueing paradigms, is a performance cost associated with previously attended locations and has been suggested as a crucial attentional mechanism that biases orientation towards novelty. In their seminal IOR paper, Posner and Cohen (1984) showed that IOR is coded in spat...

journal_title：Scientific reports

authors： He T,Ding Y,Wang Z

更新日期：2015-11-13 00:00:00

abstract：:V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA) is an immune checkpoint that maintains peripheral T cell quiescence and inhibits anti-tumor immune responses. VISTA functions by dampening the interaction between myeloid cells and T cells, orthogonal to PD-1 and other checkpoints of the tumor-T cell...

journal_title：Scientific reports

authors： Mehta N,Maddineni S,Kelly RL,Lee RB,Hunter SA,Silberstein JL,Parra Sperberg RA,Miller CL,Rabe A,Labanieh L,Cochran JR

更新日期：2020-09-16 00:00:00

abstract：:Desert locusts (Schistocerca gregaria) show a dramatic form of socially induced phenotypic plasticity known as phase polyphenism. In the absence of conspecifics, locusts occur in a shy and cryptic solitarious phase. Crowding with conspecifics drives a behavioural transformation towards gregariousness that occurs withi...

journal_title：Scientific reports

authors： Mallon EB,Amarasinghe HE,Ott SR

更新日期：2016-10-18 00:00:00

abstract：:A new compact silicon grating coupler enabling fibre-to-chip light coupling at a minimized taper length is proposed. The proposed coupler, which incorporates a hollow tapered waveguide, converts the spot-size of optical modes from micro- to nano-scales by reducing the lateral dimension from 15 µm to 300 nm at a length...

journal_title：Scientific reports

authors： Asaduzzaman M,Bakaul M,Skafidas E,Khandokar MRH

更新日期：2018-02-07 00:00:00

abstract：:We explored the potential relevance of aqueous lysophosphatidic acid (LPA) and autotaxin (ATX) levels on postoperative outcomes of trabeculectomy, and the effects of ATX on fibrotic response in cultured human conjunctiva fibroblast (HCF) cells. We enrolled 70 glaucomatous eyes which underwent trabeculectomy, and quant...

journal_title：Scientific reports

authors： Igarashi N,Honjo M,Kurano M,Yatomi Y,Igarashi K,Kano K,Aoki J,Aihara M

更新日期：2018-07-27 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Rosa SP,Costa C,Kramp K,Kundrata R

更新日期：2020-02-25 00:00:00

abstract：:In spin-based nanosystems for quantum information processing, electron spin qubits are subject to decoherence due to their interactions with nuclear spin environments. In this paper, we present an exact master equation for a central spin-1/2 system in time-dependent external fields and coupled to a spin-half bath in t...

journal_title：Scientific reports

authors： Jing J,Wu LA

更新日期：2018-01-24 00:00:00

abstract：:Owing to the diversity of pulse-wave morphology, pulse-based diagnosis is difficult, especially pulse-wave-pattern classification (PWPC). A powerful method for PWPC is a convolutional neural network (CNN). It outperforms conventional methods in pattern classification due to extracting informative abstraction and featu...

journal_title：Scientific reports

authors： Li G,Watanabe K,Anzai H,Song X,Qiao A,Ohta M

更新日期：2019-10-17 00:00:00

abstract：:The aim of the present study was to evaluate the association between statin use and the risk of age-related macular degeneration (AMD). A systematic search of the PubMed, EMBASE and ISI web of science databases was used to identify eligible published literatures without language restrictions up to April 2015. Summary ...

journal_title：Scientific reports

authors： Ma L,Wang Y,Du J,Wang M,Zhang R,Fu Y

更新日期：2015-12-14 00:00:00

abstract：:The photo-reduction of metal ions in solution induced by femtosecond laser is an important and novel method for fabricating three-dimensional metal microstructures. However, the nonlinear absorption cross section of metal ions remains unknown because its measurement is difficult. In the present study, a method based o...

journal_title：Scientific reports

authors： Ma ZC,Chen QD,Han B,Liu XQ,Song JF,Sun HB

更新日期：2015-12-11 00:00:00

abstract：:Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic and eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find that even small amounts of polymer in solution can drastically change E. co...

journal_title：Scientific reports

authors： Patteson AE,Gopinath A,Goulian M,Arratia PE

更新日期：2015-10-28 00:00:00

abstract：:Animals thriving in hot deserts rely on extraordinary adaptations and thermoregulatory capacities to cope with heat. Uncovering such adaptations, and how they may be favoured by selection, is essential for predicting climate change impacts. Recently, the arid-adapted zebra finch was discovered to program their offspri...

journal_title：Scientific reports

authors： Pessato A,McKechnie AE,Buchanan KL,Mariette MM

更新日期：2020-11-03 00:00:00

abstract：:Stress is one of major factors that cause sleep problems. Hypocretin represents a stress-related neuropeptide and is well known in maintaining physiological wakefulness. The hypocretinergic neurons originate in the lateral hypothalamic area (LHA) and transmit to several brain regions, including the median raphe nuclei...

journal_title：Scientific reports

authors： Hsiao YT,Lo Y,Yi PL,Chang FC

更新日期：2019-06-03 00:00:00

abstract：:Norfloxacin (NOF) is an environmentally harmful and ubiquitous aquatic pollutant with extensive production and application. In this study, a novel composition named carbon-based composite photocatalytic material of zinc oxide and zinc sulphide (ZnO/ZnS@BC) was successfully obtained by the impregnation-roasting method ...

journal_title：Scientific reports

authors： Liu W,He T,Wang Y,Ning G,Xu Z,Chen X,Hu X,Wu Y,Zhao Y

更新日期：2020-07-17 00:00:00

abstract：:Crops have different strategies to acquire poorly-available soil phosphorus (P) which are dependent on their architectural, morphological, and physiological root traits, but their capacity to enhance P acquisition varies with the type of fertilizer applied. The objective of this study was to examine how P-acquisition ...

journal_title：Scientific reports

authors： Nobile C,Houben D,Michel E,Firmin S,Lambers H,Kandeler E,Faucon MP

更新日期：2019-10-16 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Tan FN,Gan WL,Ang CCI,Wong GDH,Liu HX,Poh F,Lew WS

更新日期：2019-11-21 00:00:00