Abstract:
:To unravel the molecular mechanism of defense against blister blight (BB) disease caused by an obligate biotrophic fungus, Exobasidium vexans, transcriptome of BB interaction with resistance and susceptible tea genotypes was analysed through RNA-seq using Illumina GAIIx at four different stages during ~20-day disease cycle. Approximately 69 million high quality reads were assembled de novo, yielding 37,790 unique transcripts with more than 55% being functionally annotated. Differentially expressed, 149 defense related transcripts/genes, namely defense related enzymes, resistance genes, multidrug resistant transporters, transcription factors, retrotransposons, metacaspases and chaperons were observed in RG, suggesting their role in defending against BB. Being present in the major hub, putative master regulators among these candidates were identified from predetermined protein-protein interaction network of Arabidopsis thaliana. Further, confirmation of abundant expression of well-known RPM1, RPS2 and RPP13 in quantitative Real Time PCR indicates salicylic acid and jasmonic acid, possibly induce synthesis of antimicrobial compounds, required to overcome the virulence of E. vexans. Compendiously, the current study provides a comprehensive gene expression and insights into the molecular mechanism of tea defense against BB to serve as a resource for unravelling the possible regulatory mechanism of immunity against various biotic stresses in tea and other crops.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Jayaswall K,Mahajan P,Singh G,Parmar R,Seth R,Raina A,Swarnkar MK,Singh AK,Shankar R,Sharma RKdoi
10.1038/srep30412subject
Has Abstractpub_date
2016-07-28 00:00:00pages
30412issn
2045-2322pii
srep30412journal_volume
6pub_type
杂志文章abstract::Efforts for tissue engineering vascular grafts focuses on the tunica media and intima, although the tunica adventitia serves as the primary structural support for blood vessels. In surgery, during endarterectomies, surgeons can strip the vessel, leaving the adventitia as the main strength layer to close the vessel. He...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21681-7
更新日期:2018-02-19 00:00:00
abstract::People of north-eastern states of India consume raw areca-nut (RAN) and lime which could lead to oral, esophageal and gastric cancers. However, the incidence of these cancers are significantly lesser in those who consume pieces of Potentilla fulgens root along with RAN. Since evaluation of anticancer role, if any, of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53747-5
更新日期:2019-11-18 00:00:00
abstract::Targeting epigenetic reader proteins by small molecule inhibitors represents a new therapeutic concept in autoimmune diseases such as rheumatoid arthritis (RA). Although inhibitors targeting bromodomain protein 1 (BRD1) are in development, the function of BRD1 has hardly been studied. We investigated the therapeutic p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29127-w
更新日期:2018-07-24 00:00:00
abstract::Mid-infrared sensors detect infrared radiation emitted from objects, and are actually widely used for monitoring gases and moisture as well as for imaging objects at or above room temperature. Infrared photodetectors offer fast detection, but many devices cannot provide high responsivity at room temperature. Here we d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68461-w
更新日期:2020-07-15 00:00:00
abstract::The aim of this study was to identify mRNA targets of dysregulated miRNAs through the integrated analysis of miRNA and mRNA expression profiling in men with normal versus impaired spermatogenesis. The expression of mRNAs and miRNAs in testicular tissues obtained from males with non-obstructive azoospermia (NOA, n = 4)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07922
更新日期:2015-01-28 00:00:00
abstract::The aim of this systematic review was to assess the performance of anthropometric tools to determine obesity in the general population (CRD42018086888). Our review included 32 studies. To detect obesity with body mass index (BMI), the meta-analyses rendered a sensitivity of 51.4% (95% CI 38.5-64.2%) and a specificity ...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-020-69498-7
更新日期:2020-07-29 00:00:00
abstract::Emergence and time evolution of micro-structured new-phase domains play a crucial role in determining the macroscopic physical and mechanical behaviors of iron under shock compression. Here, we investigate, through molecular dynamics simulations and theoretical modelings, shock-induced phase transition process of iron...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03628
更新日期:2014-01-10 00:00:00
abstract::Stony corals form the foundation of coral reef ecosystems. Their phylogeny is characterized by a deep evolutionary divergence that separates corals into a robust and complex clade dating back to at least 245 mya. However, the genomic consequences and clade-specific evolution remain unexplored. In this study we have pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17484-x
更新日期:2017-12-14 00:00:00
abstract::In this paper, we propose an angle- and polarization-insensitive metamaterial absorber. We design a metamaterial unit cell that is based on a split ring cross resonator (SRCR). We observe that the absorption frequency and absorption ratio are insensitive to incident angles when a via array surrounds the SRR. We demons...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39686
更新日期:2016-12-21 00:00:00
abstract::We aimed to assess the role of computerized tomography attenuation values (Hounsfield unit-HU) for differentiating pyonephrosis from hydronephrosis and for predicting postoperative infectious complications in patients with obstructive uropathy. We analysed data from 122 patients who underwent nephrostomy tube or urete...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75672-8
更新日期:2020-10-29 00:00:00
abstract::Although the GW approximation is recognized as one of the most accurate theories for predicting materials excited states properties, scaling up conventional GW calculations for large systems remains a major challenge. We present a powerful and simple-to-implement method that can drastically accelerate fully converged ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36849
更新日期:2016-11-11 00:00:00
abstract::Soft tissue prostheses such as artificial ear, eye and nose are widely used in the maxillofacial rehabilitation. In this report we demonstrate how to fabricate soft prostheses mold with a low cost desktop 3D printer. The fabrication method used is referred to as Scanning Printing Polishing Casting (SPPC). Firstly the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06973
更新日期:2014-11-27 00:00:00
abstract::To construct a machine learning algorithm model of lymph node metastasis (LNM) in patients with poorly differentiated-type intramucosal gastric cancer. 1169 patients with postoperative gastric cancer were divided into a training group and a test group at a ratio of 7:3. The model for lymph node metastasis was establis...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80582-w
更新日期:2021-01-14 00:00:00
abstract::Neospora caninum is an apicomplexan parasite responsible for major economic losses due to abortions in cattle. Innate immune responses are crucial for host resistance against the infection, however the molecules involved in parasite recognition are still poorly understood. Nod2 is a cytosolic receptor that recognizes ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29289
更新日期:2016-07-05 00:00:00
abstract::Influenza virus neuraminidase (NA) is the primary target for influenza therapeutics. Severe complications are often related to secondary pneumonia caused by Streptococcus pneumoniae (pneumococci), which also express NAs. Recently, a NA-mediated lethal synergism between influenza A viruses and pneumococci was described...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27156
更新日期:2016-06-03 00:00:00
abstract::Transition Metal Dichalcogenides (TMDs) are one of the most studied two-dimensional materials in the last 5-10 years due to their extremely interesting layer dependent properties. Despite the presence of vast research work on TMDs, the complex relation between the electro-chemical and physical properties make them the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58149-6
更新日期:2020-02-03 00:00:00
abstract::HilD is an AraC-like transcriptional regulator encoded in the Salmonella pathogenicity island 1 (SPI-1), which actives transcription of many genes within and outside SPI-1 that are mainly required for invasion of Salmonella into host cells. HilD controls expression of target genes directly or by acting through distinc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49192-z
更新日期:2019-09-04 00:00:00
abstract::Three carbapenem-resistant Escherichia coli were recovered from rectal swabs of different patients in a tertiary hospital and were found carrying bla NDM-4, an uncommon bla NDM variant. Genome sequences of the isolates were obtained using Illumina technology and the long-read MinION sequencer. The isolates belonged to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18910-w
更新日期:2018-01-10 00:00:00
abstract::In contemporary muscle-computer interfaces for upper limb prosthetics there is often a trade-off between control robustness and range of executable movements. As a very low movement error rate is necessary in practical applications, this often results in a quite severe limitation of controllability; a problem growing ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43676-8
更新日期:2019-05-10 00:00:00
abstract::Once activated, the intracellular receptor NLRP3 assembles an inflammasome protein complex that facilitates the caspase-1-mediated maturation of IL-1β and IL-18. Inactive NLRP3 is guarded by a protein complex containing Hsp90. In response to stress stimuli, Hsp90 is released, and NLRP3 can be activated to promote infl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25123-2
更新日期:2018-04-30 00:00:00
abstract::Transgenic rice producing insecticidal proteins from Bacillus thuringiensis (Bt) could help protect the plants from damage by lepidopteran pests. However, one concern is the potential of Bt rice to harm non-target natural enemies, which play a vital role in pest control. In the present study, the potential effects of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08173-w
更新日期:2017-08-10 00:00:00
abstract::Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis (TB) and induces highly variable protection against pulmonary disease in different countries. We hypothesised that DNA methylation is one of the molecular mechanisms driving variability in BCG-induced immune responses. DNA methylation in peri...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31537-9
更新日期:2018-08-30 00:00:00
abstract::Rheumatoid arthritis (RA) is a chronic inflammatory condition with variable clinical presentation and disease progression. Importantly, animal models of RA are widely used to examine disease pathophysiology/treatments. Here, we exploited known vendor colony-based differences in endocrine/immune responses to gain insig...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00652-4
更新日期:2017-04-06 00:00:00
abstract::We report measurements of the thermal conductance of a structure made from commercial Acrylonitrile Butadiene Styrene (ABS) modules, known as LEGO® blocks, in the temperature range from 70 mK to 1.8 K. A power law for the sample's thermal conductivity κ = (8.7 ± 0.3) × 10-5 T 1.75±0.02 WK-1 m-1 was determined. We conc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55616-7
更新日期:2019-12-23 00:00:00
abstract::From the 1950s, the Po delta, one of the largest anthropogenic world deltas, has been subjected to a fast degradation and shoreline retreat due a marked reduction of sediment supply, mainly controlled by human impacts/factors, including subsidence. Through the interpretation of satellite images, coupled with the analy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21928-3
更新日期:2018-02-22 00:00:00
abstract::Elevated ground-level ozone (O3), which is an important aspect of air quality related to public health, has been causing increasing concern. This study investigated the spatiotemporal distribution of ground-level O3 concentrations in China using a dataset from the Chinese national air quality monitoring network during...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03929-w
更新日期:2017-06-16 00:00:00
abstract::Neutron grating interferometry (nGI) is a unique technique allowing to probe magnetic and nuclear properties of materials not accessible in standard neutron imaging. The signal-to-noise ratio of an nGI setup is strongly dependent on the achievable visibility. Hence, for analysis of weak signals or short measurement ti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58504-7
更新日期:2020-02-04 00:00:00
abstract::Nitrate treatment has been widely used in various seawater injection projects to treat biologic sulfate reduction or reservoir souring. To design a promising nitrate treatment plan, it is essential to have a comprehensive understanding of reactions that represent the microbial communities of the reservoir and mechanis...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44033-5
更新日期:2019-05-17 00:00:00
abstract::We present and demonstrate an approach for femtosecond laser processing by using patterned vector optical fields (PVOFs) composed of multiple individual vector optical fields. The PVOFs can be flexibly engineered due to the diversity of individual vector optical fields in spatial arrangement and distribution of states...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02281
更新日期:2013-01-01 00:00:00
abstract::The effects of tumorigenesis and tumor growth on the non-involved organs remain poorly understood although many research efforts have already been made for understanding the metabolic phenotypes of various tumors. To better the situation, we systematically analyzed the metabolic phenotypes of multiple non-involved mou...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28057
更新日期:2016-06-22 00:00:00