Abstract：
:The recent Paris UNFCCC climate meeting discussed the possibility of limiting global warming to 2 °C since pre-industrial times, or possibly even 1.5 °C, which would require major future emissions reductions. However, even if climate is stabilised at current atmospheric greenhouse gas (GHG) concentrations, those warming targets would almost certainly be surpassed in the context of mean temperature increases over land only. The reason for this is two-fold. First, current transient warming lags significantly below equilibrium or "committed" warming. Second, almost all climate models indicate warming rates over land are much higher than those for the oceans. We demonstrate this potential for high eventual temperatures over land, even for contemporary GHG levels, using a large set of climate models and for which climate sensitivities are known. Such additional land warming has implications for impacts on terrestrial ecosystems and human well-being. This suggests that even if massive and near-immediate emissions reductions occur such that atmospheric GHGs increase further by only small amounts, careful planning is needed by society to prepare for higher land temperatures in an eventual equilibrium climatic state.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Huntingford C,Mercado LMdoi
10.1038/srep30294subject
Has Abstractpub_date
2016-07-27 00:00:00pages
30294issn
2045-2322pii
srep30294journal_volume
6pub_type
杂志文章abstract：:The analysis of DNA methylation at CpG dinucleotides has become a major research focus due to its regulatory role in numerous biological processes, but the requisite need for assays which amplify bisulfite-converted DNA represents a major bottleneck due to the unique design constraints imposed on bisulfite-PCR primers...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41328
更新日期：2017-01-24 00:00:00
abstract：:We introduce a setup which realises a tunable engineered environment for experiments in circuit quantum electrodynamics. We illustrate this concept with the specific example of a quantum bit, qubit, in a high-quality-factor cavity which is capacitively coupled to another cavity including a resistor. The temperature of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01987
更新日期：2013-01-01 00:00:00
abstract：:Cardiorenal syndrome is defined by primary heart failure conditions influencing or leading to renal injury or dysfunction. Dilated cardiomyopathy (DCM) is a major co-existing form of heart failure (HF) with renal diseases. Myocardin (MYOCD), a cardiac-specific co-activator of serum response factor (SRF), is increased ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42009-z
更新日期：2019-04-10 00:00:00
abstract：:Programmed cell death 1 (PD-1) monoclonal antibodies have been approved by regulatory agencies for the treatment of various types of cancer, and the mechanism involves the restoration of T cell functions. We report herein the X-ray crystal structure of a fully human monoclonal antibody mAb059c fragment antigen-binding...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54231-w
更新日期：2019-11-28 00:00:00
abstract：:In this work we revisit the important and controversial concept of quantum weak values, aiming to provide a simplified understanding to its associated physics and the origin of anomaly. Taking the Stern-Gerlach setup as a working system, we base our analysis on an exact treatment in terms of quantum Bayesian approach....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20286
更新日期：2016-02-03 00:00:00
abstract：:Angiogenesis, the formation of new blood vessels, is a vital process for tissue growth and development. The Notch cell-cell signalling pathway plays an important role in endothelial cell specification during angiogenesis. Dll4 - Notch1 signalling directs endothelial cells into migrating tip or proliferating stalk cell...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24646-y
更新日期：2018-04-23 00:00:00
abstract：:Circulating miRNAs have attracted attention as serum biomarkers for several diseases. In this study, we aimed to evaluate the diagnostic value of circulating miRNA-21 (miR-21) as a novel biomarker for elderly patients with type 2 cardiorenal syndrome (CRS-2). A total of 157 elderly patients with chronic heart failure ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61836-z
更新日期：2020-03-17 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-66769-1
更新日期：2020-06-16 00:00:00
abstract：:Sterility mosaic disease (SMD) is one of the serious production constraints that may lead to complete yield loss in pigeonpea. Three mapping populations including two recombinant inbred lines and one F2, were used for phenotyping for SMD resistance at two locations in three different years. Genotyping-by-sequencing ap...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01535-4
更新日期：2017-05-12 00:00:00
abstract：:The patterns of life exhibited by large populations have been described and modeled both as a basic science exercise and for a range of applied goals such as reducing automotive congestion, improving disaster response, and even predicting the location of individuals. However, these studies have had limited access to c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02625
更新日期：2013-01-01 00:00:00
abstract：:Inhibitor of kappa B (IκB)-ζ transcription is rapidly induced by stimulation with TLR ligands and IL-1. Despite high IκBζ expression in inflammation sites, the association of IκBζ with host defence via systemic immune responses against bacterial infection remains unclear. Oral immunisation with a recombinant attenuate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44019-3
更新日期：2019-06-10 00:00:00
abstract：:The bronchoscopy, though usually safe, is occasionally associated with complications, such as pneumonia. However, the use of prophylactic antibiotics is not recommended by the guidelines of the British Thoracic Society. Thus far there are few reports of the risk factors for post-bronchoscopy pneumonia; the purpose of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76998-z
更新日期：2020-11-17 00:00:00
abstract：:Post-transcriptional gene regulation by microRNAs (miRNAs) is involved in memory formation. However, the roles of individual miRNAs in these processes remain largely unknown. In this study, we want to clarify the role of miR-181a in hippocampus-dependent memory formation. A transient increase in miR-181a expression wa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09095-3
更新日期：2017-08-16 00:00:00
abstract：:Observations and modeling studies have shown that during CO2 injection into underground carbonate reservoirs, the dissolution of CO2 into formation water forms acidic brine, leading to fluid-rock interactions that can significantly impact the hydraulic properties of the host formation. However, the impacts of these in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60247-4
更新日期：2020-02-27 00:00:00
abstract：:The human foot and ankle system is equipped with structures that can produce mechanical work through elastic (e.g., Achilles tendon, plantar fascia) or viscoelastic (e.g., heel pad) mechanisms, or by active muscle contractions. Yet, quantifying the work distribution among various subsections of the foot and ankle can ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15218-7
更新日期：2017-11-13 00:00:00
abstract：:Autophagy is an essential cellular mechanism that degrades cytoplasmic proteins and organelles to recycle their components; however, the contribution of autophagy during meiosis has not been studied in porcine oocytes maturing in vitro. In this study, we observed that the autophagy-related gene, LC3, was expressed in ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-29872-y
更新日期：2018-08-22 00:00:00
abstract：:Sexual segregation in foraging occurs in many animal species, resulting in the partitioning of resources and reduction of competition between males and females, yet the patterns and drivers of such segregation are still poorly understood. We studied the foraging movements (GPS-tracking), habitat use (habitat modelling...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02854-2
更新日期：2017-06-01 00:00:00
abstract：:Sub-retinal fluid (SRF) has been discussed as a protective factor against macular atrophy in eyes with neovascular age-related macular degeneration (nAMD).To gauge the impact of SRF on macular atrophy, a database of 310 nAMD eyes was screened for eyes manifesting an SRF-only phenotype under treat & extend anti-VEGF tr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64901-9
更新日期：2020-05-15 00:00:00
abstract：:Spintronic devices currently rely on magnetic switching or controlled motion of domain walls by an external magnetic field or spin-polarized current. Achieving the same degree of magnetic controllability using an electric field has potential advantages including enhanced functionality and low power consumption. Here w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00258
更新日期：2012-01-01 00:00:00
abstract：:The neuronal accumulation of phosphorylated tau plays a critical role in the pathogenesis of Alzheimer's disease (AD). Here, we examined the effect of fisetin, a flavonol, on tau levels. Treatment of cortical cells or primary neurons with fisetin resulted in significant decreases in the levels of phosphorylated tau. I...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24933
更新日期：2016-04-26 00:00:00
abstract：:Saliva has immense potential as a diagnostic fluid for identification and monitoring of several systemic diseases. Composition of the microbiome and inflammation has been associated and reflective of oral and overall health. In addition, the relative ease of collection of saliva further strengthens large-scale diagnos...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81420-3
更新日期：2021-01-29 00:00:00
abstract：:Superconductivity within layered crystal structures has attracted sustained interest among condensed matter community, primarily due to their exotic superconducting properties. EuBiS2F is a newly discovered member in the BiS2-based superconducting family, which shows superconductivity at 0.3 K without extrinsic doping...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37394
更新日期：2016-11-22 00:00:00
abstract：:We characterize the changes in chromatin structure, DNA methylation and transcription during and after homologous DNA repair (HR). We find that HR modifies the DNA methylation pattern of the repaired segment. HR also alters local histone H3 methylation as well chromatin structure by inducing DNA-chromatin loops connec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33222
更新日期：2016-09-15 00:00:00
abstract：:The spreading of cooperation in structured population is a challenging problem which can be observed at different scales of social and biological organization. Generally, the problem is studied by evaluating the chances that few initial invading cooperators, randomly appearing in a network, can lead to the spreading o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80770-8
更新日期：2021-01-13 00:00:00
abstract：:By growing monolayer FeSe on SrTiO3(001) surface, researchers obtain the highest superconducting transition-temperature for iron-based superconductor. Here, we study the antiferromagnetic (AFM) checkerboard monolayer FeSe adsorbed on SrTiO3(001) surface. We show that the system has a considerable charge transfer from ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02213
更新日期：2013-01-01 00:00:00
abstract：:The limits of mammography have led to an increasing interest on possible alternatives such as the breast Computed Tomography (bCT). The common goal of all X-ray imaging techniques is to achieve the optimal contrast resolution, measured through the Contrast to Noise Ratio (CNR), while minimizing the radiological risks,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49351-2
更新日期：2019-09-11 00:00:00
abstract：:Neuroinflammation is involved in the pathogenesis of Parkinson's disease (PD) and other neurodegenerative disorders. We show that lack of PINK1- a mitochondrial kinase linked to recessive familial PD - leads to glia type-specific abnormalities of innate immunity. PINK1 loss enhances LPS/IFN-γ stimulated pro-inflammato...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18786-w
更新日期：2018-01-10 00:00:00
abstract：:Mathematical models of metabolism from bacterial systems biology have proven their utility across multiple fields, for example metabolic engineering, growth phenotype simulation, and biological discovery. The usefulness of the models stems from their ability to compute a link between genotype and phenotype, but their ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16025
更新日期：2015-11-04 00:00:00
abstract：:Plasma proteins such as fibrinogen induce the aggregation of red blood cells (RBC) into rouleaux, which are responsible for the pronounced shear thinning behavior of blood, control the erythrocyte sedimentation rate (ESR) - a common hematological test - and are involved in many situations of physiological relevance su...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07634-6
更新日期：2017-08-11 00:00:00
abstract：:We investigated the effect of a new Rho kinase inhibitor, SB772077B (SB77) on aqueous outflow facility (OF) in human eyes using human organ-cultured anterior segment (HOCAS). IOP was monitored for 24 h post-treatment with either SB77 (0.1/10/50 µM) or vehicle after a stable baseline pressure. The hydrodynamic pattern ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33932-8
更新日期：2018-10-19 00:00:00
