Primary rhabdomyosarcoma of the distal femoral diaphysis: a case report and review of the literature.

Abstract:

:Primary rhabdomyosarcoma of the bone is an extremely rare condition with few examples reported in the literature. We present the case of a 34-year-old male who presented with a lesion in the distal femur with initial imaging features consistent with Ewing sarcoma. Histologically, the lesion consisted of atypical pleomorphic polygonal rhabdomyoblasts demonstrating focal desmin and myogenin expression. A diagnosis of pleomorphic rhabdomyosarcoma was rendered. Despite systemic treatment and surgery, this patient experienced a rapidly progressive disease course. We believe this is only the second report in the orthopedic literature of a case of primary pleomorphic rhabdomyosarcoma of the bone. The key imaging, pathologic, and clinical findings are discussed.

journal_name

Skeletal Radiol

journal_title

Skeletal radiology

authors

Bressner JA,McCarthy EF,Fayad LM,Morris CD

doi

10.1007/s00256-016-2430-7

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

1391-5

issue

10

eissn

0364-2348

issn

1432-2161

pii

10.1007/s00256-016-2430-7

journal_volume

45

pub_type

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