Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.

Abstract:

:A water-soluble polysaccharide (EPA-1) from Pleurotus eryngii was obtained using DEAE-52 and Sephadex G-50 columns. The properties, structure and immunomodulatory activity of EPA-1 were studied. The results demonstrated that EPA-1 was a homogeneous polysaccharide with the molecular weight of 9.97×104Da. EPA-1 consisted of Man, Glc and Gal in a molar ratio of 2.2:1.0:3.2. The characterized fragment structures of EPA-1 were found to be consisting of seven sugar residues and two branches by GC-MS, FTIR and NMR analyses. Among them, the (1→6)-linkedGal residue was the main linkage mode of EpA-1 and composed of its backbone. Activity tests indicated that EPA-1 significantly induced macrophage to release the immune activity factor of NO, TNF-α, IL-1 and IL-6 through activation of signal protein of p38, ERK, JNK in MAPKs and translocation of nuclear NF-κΒ, indicating EPA-1 to possess good immunoregulatory activity.

journal_name

Int J Biol Macromol

authors

Xu D,Wang H,Zheng W,Gao Y,Wang M,Zhang Y,Gao Q

doi

10.1016/j.ijbiomac.2016.07.016

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

30-36

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(16)30739-5

journal_volume

92

pub_type

杂志文章
  • Orabase formulation with cashew gum polysaccharide decreases inflammatory and bone loss hallmarks in experimental periodontitis.

    abstract::This study aimed to investigate the chemical characteristics and the effects of an orabase gel with Cashew Gum Polysaccharide (CG-P) from Anacardium occidentale L. on alveolar bone loss and relative mRNA expression of TNF-α, IL-1β, RANK, RANKL, and OPG in the periodontal tissue of Wistar rats (Rattus norvegicus) subje...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.09.087

    authors: Souza Filho MD,Medeiros JVR,Vasconcelos DFP,Silva DA,Leódido ACM,Fernandes HF,Silva FRP,França LFC,Lenardo D,Pinto GR

    更新日期:2018-02-01 00:00:00

  • Rheological study of albumin and hyaluronan-albumin hydrogels: Effect of concentration, ionic strength, pH and molecular weight.

    abstract::Albumin and hyaluronic acid are biodegradable, endogenous substances with potential use as drug carriers. These properties combined with the physical structure of the gel can lead to the formation of biologically active materials with application in medicine. This work investigated the gelation process of albumin solu...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.06.063

    authors: Hájovská P,Chytil M,Kalina M

    更新日期:2020-10-15 00:00:00

  • Partial purification and MALDI-TOF MS analysis of UN1, a tumor antigen membrane glycoprotein.

    abstract::UN1 is a membrane glycoprotein that is expressed in immature human thymocytes, a subpopulation of peripheral T lymphocytes, the HPB acute lymphoblastic leukemia (ALL) T-cell line and fetal thymus. We previously reported the isolation of a monoclonal antibody (UN1 mAb) recognizing the UN1 protein that was classified as...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2006.02.020

    authors: de Laurentiis A,Caterino M,Orrù S,Ruoppolo M,Tuccillo F,Masullo M,Quinto I,Scala G,Pucci P,Palmieri C,Tassone P,Salvatore F,Venuta S

    更新日期:2006-08-15 00:00:00

  • Functional characterization of a type 2 metallothionein isoform (OsMTI-2b) from rice.

    abstract::Metallothioneins (MTs) are a family of Cys-rich, low molecular weight, cytoplasmic metal binding proteins. MTs are present in all eukaryotes as well as some prokaryotes. Plant MTs are divided into four types based on Cys distribution pattern in their amino acid sequences. In the present work, the gene encoding OsMTI-2...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2016.04.021

    authors: Pirzadeh S,Shahpiri A

    更新日期:2016-07-01 00:00:00

  • Basic Helix-Loop-Helix (bHLH) transcription factor family in Yellow horn (Xanthoceras sorbifolia Bunge): Genome-wide characterization, chromosome location, phylogeny, structures and expression patterns.

    abstract::Yellow horn (Xanthoceras sorbifolia Bunge) is a oil-rich, woody deciduous shrub with exceptional economic and ecological values. Basic Helix-Loop-Helix (bHLH) transcription factor (TF) family fulfills crucial biological functions in plant. However, genome-wide survey of the bHLH genes in yellow horn has not been perfo...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.05.253

    authors: Lang Y,Liu Z

    更新日期:2020-10-01 00:00:00

  • Preparation and characterization of chitosan/gelatin/nanocrystalline cellulose/calcium peroxide films for potential wound dressing applications.

    abstract::In order to improve mechanical properties and biomedical behavior of chitosan-based polymeric films, the effect of nanocrystalline cellulose (NCC) and calcium peroxide (CP) particles on the properties of polymeric films based on chitosan (CS) and gelatin (GL) were investigated in this study. The films were characteriz...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.04.159

    authors: Akhavan-Kharazian N,Izadi-Vasafi H

    更新日期:2019-07-15 00:00:00

  • Antioxidant and antibacterial chitosan film with tea polyphenols-mediated green synthesis silver nanoparticle via a novel one-pot method.

    abstract::In the present study, the antioxidant and antibacterial chitosan/tea polyphenols-silver nanoparticles composite film (CS/TP-AgNPs) was developed via a novel one-pot method. The TP was added to the CS film not only as the reducing agent of AgNPs but also as the cross-linking agent and antioxidant. The AgNPs and nanocom...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.11.093

    authors: Zhang W,Jiang W

    更新日期:2020-07-15 00:00:00

  • Salt-regulated reversible fibrillation of Mycobacterium tuberculosis isocitrate lyase: Concurrent restoration of structure and activity.

    abstract::Protein fibrillation is associated with a number of neurodegenerative diseases. Nevertheless, several proteins not related to disease can also form fibrils in vitro under specific conditions. In the present study, we demonstrate the reversible fibrillation of a globular protein that is modulated by salt under physiolo...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.06.008

    authors: Shukla H,Kumar R,Sonkar A,Mitra K,Akhtar MS,Tripathi T

    更新日期:2017-11-01 00:00:00

  • Polysaccharides from loquat (Eriobotrya japonica) leaves: Impacts of extraction methods on their physicochemical characteristics and biological activities.

    abstract::Impacts of hot water extraction (HWE), pressurized water extraction (PWE), high-speed shearing homogenization extraction, microwave assisted extraction (MAE), ultrasound assisted extraction (UAE), ultrasound assisted enzymatic extraction, and ultrasound-microwave assisted extraction (UMAE) on physicochemical character...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.12.273

    authors: Fu Y,Li F,Ding Y,Li HY,Xiang XR,Ye Q,Zhang J,Zhao L,Qin W,Gan RY,Wu DT

    更新日期:2020-03-01 00:00:00

  • Distribution of solvent and ligand molecules around aromatic side chains in proteins and its implication on carbonic anhydrase catalytic mechanism.

    abstract::Interactions between aromatic phenylalanine, tyrosine and tryptophan residues and water as well as ligand molecules were analyzed by a computer search of a large number of high resolution structures in the protein data bank. Water molecules and oxygen ligands have a preference for the edges of the aromatic residues, b...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/0141-8130(95)01068-8

    authors: Håkansson K

    更新日期:1996-04-01 00:00:00

  • Inhibition of methemoglobin formation in aqueous solutions under aerobic conditions by the addition of amino acids.

    abstract::Hemoglobin (Hb) as an important iron-containing oxygen-transport protein is easily oxidized to the ferric met-form, methemoglobin (metHb), and loses the capacity of binding oxygen during storage. In this study, the experimental data indicate that the presence of Tyr and Glu significantly suppress the metHb formation i...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2013.12.010

    authors: Wei Y,Li C,Zhang L,Su Z,Xu X

    更新日期:2014-03-01 00:00:00

  • Facile immobilization of Bacillus licheniformis γ-glutamyltranspeptidase onto graphene oxide nanosheets and its application to the biocatalytic synthesis of γ-l-glutamyl peptides.

    abstract::For the practical application of Bacillus licheniformis γ-glutamyltranspeptidase (BlGGT), we illustrated a simple and efficient approach to fabricate a biocatalytic system by immobilizing the enzyme onto graphene oxide (GO) nanosheets via both non-covalent (GO-BlGGT) and covalent (GO/GA-BlGGT) bonds. The enzyme-loadin...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.11.153

    authors: Lin LL,Chi MC,Lan YJ,Lin MG,Juang TY,Wang TF

    更新日期:2018-10-01 00:00:00

  • Effect of roasting process on enzymes inactivation and starch properties of highland barley.

    abstract::Roasting may be beneficial to extend the shelf life by inactivating the lipases and peroxidases in highland barley, but it may lead to the deterioration of starch quality. In this study, the pre-treatment techniques of pearling and tempering were tried to improve the efficiency of inactivation, and different roasting ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.09.180

    authors: Zhao B,Shang J,Liu L,Tong L,Zhou X,Wang S,Zhang Y,Wang L,Zhou S

    更新日期:2020-12-15 00:00:00

  • Acid soaking followed by steam flash-explosion pretreatment to enhance saccharification of rice husk for poly(3-hydroxybutyrate) production.

    abstract::In order to exploit an abundant and cheap carbon source for poly(3-hydroxybutyrate) (PHB) production, the rice husk was pretreated with dilute sulfuric acid and steam flash-explosion to enhance the enzymatic saccharification. The yield of reducing sugars of pretreated rice husk hydrolysate came up to 266.5 mg/g rice h...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.05.218

    authors: Zhang Y,Wang L,Li T,Shen Y,Luo J

    更新日期:2020-10-01 00:00:00

  • Hypoglycemic activity in vitro of polysaccharides from Camellia oleifera Abel. seed cake.

    abstract::We isolated and purified polysaccharide from the Camellia oleifera Abel. seed cake (CCP) and studied its hypoglycemic activity in vitro. The molecular weight of CCP was 4736 Da and the monosaccharide molar composition ratio was: Xylose:Glucuronic acid:Galactosamine:Mannose = 10.9:4.4:2.6:1.8. The CCP contained conjuga...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.04.054

    authors: Zhang S,Li X

    更新日期:2018-08-01 00:00:00

  • Two-step purification procedure for recombinant human asialoerythropoietin expressed in transgenic plants.

    abstract::Asialoerythropoietin (asialo-EPO) is a desialylated form of human glycoprotein hormone erythropoietin (EPO), which has been reported to be neuro-, cardio-, and renoprotective in animal models of organ injuries. Since the current method of production of asialo-EPO from mammalian cell-made recombinant human EPO (rhuEPO(...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2014.10.033

    authors: Kittur FS,Arthur E,Nguyen M,Hung CY,Sane DC,Xie J

    更新日期:2015-01-01 00:00:00

  • Unusual reversible elastomeric gels from Nostoc commune.

    abstract::Nostoc commune cyanobacteria grow in extreme conditions of desiccation and nutrient-poor soils. Their colonies form spherical gelatinous bodies are composed of a variety of polysaccharides that allow them to store water and nutrients. In this paper, we study this type of biological gel that shows characteristics of bo...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.01.048

    authors: Rodriguez S,Gonzales KN,Romero EG,Troncoso OP,Torres FG

    更新日期:2017-04-01 00:00:00

  • Biodegradation of polyvinyl alcohol using cross-linked enzyme aggregates of degrading enzymes from Bacillus niacini.

    abstract::In this study, polyvinyl alcohol (PVA)-degrading bacteria were screened from sludge samples using PVA as a sole source of carbon. A novel strain was obtained and identified as Bacillus niacini based on the analysis of a partial 16S rDNA nucleotide sequence and morphological characteristics. PVA-degrading enzyme (PVAas...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.11.204

    authors: Bian H,Cao M,Wen H,Tan Z,Jia S,Cui J

    更新日期:2019-03-01 00:00:00

  • Synthesis and characterization of some novel antimicrobial thiosemicarbazone O-carboxymethyl chitosan derivatives.

    abstract::Three novel thiosemicarbazone O-carboxymethyl chitosan derivatives were obtained via a condensation reaction of thiosemicarbazide O-carboxymethyl chitosan with o-hydroxybenzaldehyde, p-methoxybenzaldehyde, and p- chlorobenzaldehyde respectively. Their structures were characterized by elemental analysis, FTIR, (13)C NM...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2013.10.044

    authors: Mohamed NA,Mohamed RR,Seoudi RS

    更新日期:2014-02-01 00:00:00

  • Genealogy of the alpha-crystallin--small heat-shock protein superfamily.

    abstract::Sequences of 40 very diverse representatives of the alpha-crystallin-small heat-shock protein (alpha-Hsp) superfamily are compared. Their characteristic C-terminal 'alpha-crystallin domain' of 80-100 residues contains short consensus sequences that are highly conserved from prokaryotes to eukaryotes. There are, in add...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章,评审

    doi:10.1016/s0141-8130(98)00013-0

    authors: de Jong WW,Caspers GJ,Leunissen JA

    更新日期:1998-05-01 00:00:00

  • Taro starch (Colocasia esculenta) and citric acid modified taro starch as tablet disintegrating agents.

    abstract::The objective of the present work is to study the physicochemical and functional properties of taro starch (Colocasia esculenta) and to further modify the starch by treating with citric acid to obtain a novel functional material. DSC, FTIR and SEM studies were performed along with physicochemical analysis. The disinte...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.06.086

    authors: Pachuau L,Dutta RS,Devi TB,Deka D,Hauzel L

    更新日期:2018-10-15 00:00:00

  • Impact of ionic liquid type on the structure, morphology and properties of silk-cellulose biocomposite materials.

    abstract::Microcrystalline cellulose and Bombyx mori silk blended biocomposite films were regenerated using various imidazolium-based ionic liquids. The films were characterized to understand the effect of the inter- and intra-molecular interactions upon the morphology and thermal properties. Various techniques were implemented...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.11.137

    authors: Stanton J,Xue Y,Pandher P,Malek L,Brown T,Hu X,Salas-de la Cruz D

    更新日期:2018-03-01 00:00:00

  • Co-immobilization of glucose oxidase and catalase in silica inverse opals for glucose removal from commercial isomaltooligosaccharide.

    abstract::In this work, glucose oxidase (GOD) and catalase (CAT) were co-immobilized on novel silica inverse opals (IO-SiO2) through sol-gel process. The immobilized bi-enzyme system named GOD/CAT@IO-SiO2 was successfully fabricated and characterized. Morphology characterization indicated that GOD/CAT@IO-SiO2 had hierarchical p...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.10.074

    authors: Zhao B,Zhou L,Ma L,He Y,Gao J,Li D,Jiang Y

    更新日期:2018-02-01 00:00:00

  • Evaluation of microwave assisted grafted sago starch as controlled release polymeric carrier.

    abstract::In the present investigation an attempt has been made to develop a new co-polymeric material for controlled release tablet formulations. The acrylamide grafting was successfully performed on the backbone of sago starch. The modified starch was tested for acute toxicity and drug-excipient compatibility study. The graft...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2013.05.008

    authors: Singh AV,Nath LK

    更新日期:2013-09-01 00:00:00

  • Electrochemical, spectroscopic, and theoretical studies on the interaction between azathioprine and DNA.

    abstract::Possible interaction between immunosuppressive drug, azathioprine, and calf thymus DNA was explored by cyclic voltammetry, spectrophotometry, competitive spectrofluorimetry, circular dichroism spectroscopy (CD), and viscosity measurements. Cyclic voltammetry showed negative shift in the reduction peak of azathioprine ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2015.08.025

    authors: Jalali F,Rasaee G

    更新日期:2015-11-01 00:00:00

  • Binding of bivalent cations by xanthan in aqueous solution.

    abstract::The interaction between xanthan and selected bivalent cations (Ca2+, Mg2+, Mn2+, Fe2+, Cu2+, Zn2+, Cd2+ and Pb2+) was studied by means of conductometry, viscometry, and nuclear magnetic resonance spectroscopy. Xanthan from Xanthomonas campestris was studied in comparison with dextran from Leuconostoc mesenteroides. Wh...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2008.06.001

    authors: Bergmann D,Furth G,Mayer C

    更新日期:2008-10-01 00:00:00

  • Synthesis and characterization of lactic acid esterified starch by an in-situ solid phase method.

    abstract::To improve the hydrophobicity and thermoplastic processability of starch, lactic acid esterified starch (LA-e-starch) was prepared by in-situ solid phase esterification with corn starch as the raw material and LA as the esterifying agent. Fourier transform infrared spectroscopy confirmed that the esterification reacti...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.11.171

    authors: Li P,He X,Zuo Y,Li X,Wu Y

    更新日期:2020-08-01 00:00:00

  • A novel quaternized chitosan-melamine-glutaraldehyde resin for the removal of nitrate and phosphate anions.

    abstract::A terpolymer of chitosan-melamine-glutaraldehyde was prepared for the first time and it was quaternized with glycidyl trimethyl ammonium chloride (GTMAC). The quaternized chitosan-melamine-glutaraldehyde resin (QCMGR) was found to be effective for the removal of nitrate and phosphate oxyanions. The resin was character...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2013.11.036

    authors: Sowmya A,Meenakshi S

    更新日期:2014-03-01 00:00:00

  • One pot preparation of magnetic chitosan-cystamine composites for selective recovery of Au(III) from the aqueous solution.

    abstract::A novel magnetic chitosan adsorbent (CDF-CS) was synthesized by inserting magnetic particles into the crosslinked compound of chitosan (CS) and cystamine based on one-step method for selectively recovering Au(III) from aqueous solution. The characterization and adsorption mechanism of CDF-CS were studied by SEM-EDS, V...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.07.022

    authors: Zhao M,Zhao J,Huang Z,Wang S,Zhang L

    更新日期:2019-09-15 00:00:00

  • Preparation and characterization of contact active antibacterial surface based on chemically modified nanofibrillated cellulose by phenanthridinium silane salt.

    abstract::The main object of this research is chemical modification of the nanofibrillated cellulose (NFC) surface with a phenanthridinium silane salt to develop durable non-leaching antibacterial surface. Initially, (3-trimethoxysilylpropyl) phenanthridinium iodide (TMSPhI) as an antibacterial agent was synthesized using (3-ch...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.03.141

    authors: Hassanpour A,Asghari S,Mansour Lakouraj M,Mohseni M

    更新日期:2018-08-01 00:00:00