Characterization of unrelated clinical Legionella pneumophila isolates in Catalonia by monoclonal subgrouping and sequence-based typing.

Abstract:

AIM:To characterize the genetic diversity of unrelated Legionella pneumophila clinical isolates in Catalonia and compare with other European regions. METHODS:95 unrelated isolates were analyzed using monoclonal antibodies and sequence-based typing, 1989-2013. RESULTS:The isolates showed a high diversity (IOD 0.964) with a predominance of some profiles (ST37-Phialdelphia, ST23-Philadelphia and ST1-OLDA). All regions had predominant sequence types (STs) that differed between regions, and only 3% of STs were shared between the three regions. CONCLUSION:L. pneumophila clinical isolates from Catalonia presented a high diversity and can be used in epidemiological surveillance studies. The heterogeneous predominance of STs between European regions suggested a relationship between geographical distribution and virulence of some STs.

journal_name

Future Microbiol

journal_title

Future microbiology

authors

Garcia-Nuñez M,Quero S,Pedro-Botet ML,Barrabeig I,Avarez J,Campoy I,Sala MR,Parraga-Niño N,Minguell S,Caylà J,Mateu L,Sabria M

doi

10.2217/fmb-2016-0013

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

865-75

eissn

1746-0913

issn

1746-0921

journal_volume

11

pub_type

杂志文章
  • Endothelial cells and CMV dissemination.

    abstract::Using the murine CMV animal model and the well-established model of Cre-lox-P-mediated green-fluorescence tagging of endothelial cell (EC)-derived mouse CMV to quantify the role of infected ECs in transplantation-associated CMV dissemination (in mice expressing Cre recombinase under the control of either the Tie2 or t...

    journal_title:Future microbiology

    pub_type: 评论,杂志文章

    doi:10.2217/fmb.12.12

    authors: Gerna G

    更新日期:2012-04-01 00:00:00

  • Chronic fatigue syndrome, XMRV and blood safety.

    abstract::In the past few months, there has been public discussion relating to a new perspective on blood safety and specifically upon measures to prevent or discourage donation by individuals with a diagnosis of myalgic encephalopathy-chronic fatigue syndrome. This reflects an intriguing interplay between science, public healt...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.11.24

    authors: Dodd RY

    更新日期:2011-04-01 00:00:00

  • Progress in the experimental therapy of severe arenaviral infections.

    abstract::A number of viruses in the family Arenaviridae cause severe illness in humans. Lassa virus in West Africa and a number of agents in South America produce hemorrhagic fever in persons exposed to aerosolized excretions of the pathogens' rodent hosts. Because arenaviruses are not transmitted by arthropods, and person-to-...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.11.132

    authors: Gowen BB,Bray M

    更新日期:2011-12-01 00:00:00

  • Tregs in the immune response of BALB/c mice experimentally infected with species of the Sporothrix genus.

    abstract::Background: Sporotrichosis occurs through contact with contaminated soil and plant. However, the incidence of sporotrichosis as a zoonotic epidemic has increased, particularly in Rio de Janeiro. Aim: In this work, we decided to evaluate some T-cell phenotypes involved in the immune response. Materials & methods: We us...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2020-0046

    authors: Corrêa-Moreira D,De Luca PM,Romeo O,C Menezes R,Paes RA,Oliveira RZ,de Moraes AM,de L Neto RG,Moraes Borba C,E de Oliveira MM

    更新日期:2020-09-01 00:00:00

  • Alterations of zinc homeostasis in response to Cryptococcus neoformans in a murine macrophage cell line.

    abstract:AIM:To evaluate alterations of zinc homeostasis in macrophages exposed to Cryptococcus neoformans. Materials & methods: Using a fluorescent zinc probe-based flow cytometry and atomic absorption spectrometry, zinc levels were evaluated in J774.A1 cell lines exposed to C. neoformans H99 cells. The transcription profile o...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2016-0160

    authors: Dos Santos FM,Piffer AC,Schneider RO,Ribeiro NS,Garcia AWA,Schrank A,Kmetzsch L,Vainstein MH,Staats CC

    更新日期:2017-05-01 00:00:00

  • Effects of hyperbaric oxygen on Pseudomonas aeruginosa susceptibility to imipenem and macrophages.

    abstract:BACKGROUND:The seriousness to treat burn wounds infected with Pseudomonas aeruginosa led us to examine whether the effect of the carbapenem antibiotic imipenem is enhanced by hyperbaric oxygen (HBO). MATERIALS & METHODS:The effects of HBO (100% O2, 3 ATA, 5 h) in combination with imipenen on bacterial counts of six is...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.14.111

    authors: Lima FL,Joazeiro PP,Lancellotti M,de Hollanda LM,de Araújo Lima B,Linares E,Augusto O,Brocchi M,Giorgio S

    更新日期:2015-01-01 00:00:00

  • COVID-19: mask efficacy is dependent on both fabric and fit.

    abstract::Aim: Face masks are an important addition to our arsenal in the fight against COVID-19. The aim of this study is to present a novel method of measuring mask performance which can simultaneously assess both fabric penetration and leakage due to poor fit. Materials & methods: A synthetic aerosol is introduced into the l...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2020-0292

    authors: Darby S,Chulliyallipalil K,Przyjalgowski M,McGowan P,Jeffers S,Giltinan A,Lewis L,Smith N,Sleator RD

    更新日期:2021-01-01 00:00:00

  • Letermovir for prophylaxis of cytomegalovirus manifestations in adult allogeneic hematopoietic stem cell transplant recipients.

    abstract::Cytomegalovirus (CMV) manifestations remain important complications after allogeneic hematopoietic stem cell transplantation (HSCT), even in the current era. Unfortunately, available anti-CMV agents, mainly viral polymerase inhibitors, have a substantial risk of myelosuppression and nephrotoxicity. Letermovir, a novel...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2018-0250

    authors: Hecke SV,Calcoen B,Lagrou K,Maertens J

    更新日期:2019-02-01 00:00:00

  • Evaluation of the antifungal activity in vitro of midazolam against fluconazole-resistant Candida spp. isolates.

    abstract::Aim: The purpose of this study was to evaluate the antifungal activity of midazolam, alone and in association with azoles, against isolates of clinical Candida spp. in planktonic and biofilm form. Materials & methods: The antifungal activity was observed using the broth microdilution technique. Flow cytometry tests we...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2020-0080

    authors: Holanda MA,da Silva CR,de A Neto JB,do Av Sá LG,do Nascimento FB,Barroso DD,da Silva LJ,Cândido TM,Leitão AC,Barbosa AD,de Moraes MO,Cc B,Júnior HVN

    更新日期:2021-01-01 00:00:00

  • Rotavirus disease and vaccination: impact on genotype diversity.

    abstract::Temporal and spatial fluctuations in the genotype distribution of human rotaviruses are continuously observed in surveillance studies. New genotypes, such as G9 and G12, have emerged and spread worldwide in a very short time span. In addition, reassortment events have the potential to contribute substantially to genet...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.09.96

    authors: Matthijnssens J,Bilcke J,Ciarlet M,Martella V,Bányai K,Rahman M,Zeller M,Beutels P,Van Damme P,Van Ranst M

    更新日期:2009-12-01 00:00:00

  • Raman spectroscopy: lighting up the future of microbial identification.

    abstract::Over the last decade Raman spectroscopy has become established as a physicochemical technique for the rapid identification of microbes. This powerful analytical method generates a spectroscopic fingerprint from the microbial sample, which provides quantitative and qualitative information that can be used to characteri...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.11.89

    authors: Ashton L,Lau K,Winder CL,Goodacre R

    更新日期:2011-09-01 00:00:00

  • Cryptococcus gattii infections: contemporary aspects of epidemiology, clinical manifestations and management of infection.

    abstract::Cryptococcus gattii is an important primary and opportunistic pathogen, predominantly causing meningoencephalitis and pulmonary disease with substantial mortality. Initially considered geographically restricted to immune-competent, highly exposed individuals in the tropics, an apparent epidemic in North America has le...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.13.123

    authors: McMullan BJ,Sorrell TC,Chen SC

    更新日期:2013-12-01 00:00:00

  • Therapeutic efficacy of ozenoxacin in animal models of dermal infection with Staphylococcus aureus.

    abstract:AIM:To assess different concentrations and formulations of topical ozenoxacin using a mouse model of Staphylococcus aureus dermal infection for identification of the best formulation for treating patients with impetigo. MATERIALS & METHODS:The efficacy of ozenoxacin formulations was compared with vehicle control, mupi...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2017-0290

    authors: Tarragó C,Esquirol LP,Arañó A,Lachamp L,D'Aniello F,Zsolt I

    更新日期:2018-05-01 00:00:00

  • Cryptococcal infections in children: retrospective study and review from Australia.

    abstract::Aim: Cryptococcosis causes significant morbidity and mortality worldwide, but pediatric data are limited. Methods: A retrospective literature review of Australian pediatric cryptococcosis and additional 10-year audit of cases from a large pediatric network. Results: 22 cases of cryptococcosis in children were identifi...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb-2019-0215

    authors: Grimshaw A,Palasanthiran P,Huynh J,Marais B,Chen S,McMullan B

    更新日期:2019-12-01 00:00:00

  • Measles virus hemagglutinin epitopes are potential hotspots for crossreactions with immunodeficiency-related proteins.

    abstract:AIMS:Measles virus (MV) infection induces a protective immunity that is accompanied by a transient pathologic suppression of the immune system. This immunologic paradox remains unexplained in spite of the numerous hypotheses that have been advanced (i.e., cytokine production, soluble immunosuppressive factor, cell cycl...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.14.137

    authors: Kanduc D

    更新日期:2015-01-01 00:00:00

  • The type IV secretion system in Helicobacter pylori.

    abstract::Helicobacter pylori (H. pylori) has an essential role in the pathogenesis of gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma and gastric cancer. The severity of the host inflammatory responses against the bacteria have been straightly associated with a special bacterial virulence factor, th...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb-2018-0038

    authors: Yuan XY,Wang Y,Wang MY

    更新日期:2018-07-01 00:00:00

  • Use of the plaque assay for testing the antibiotic susceptibility of intracellular bacteria.

    abstract::The plaque assay was first described for titration of bacterial inoculums and clonal isolation, and was later adapted for testing antibiotics susceptibility and to study virulence factors and motility of bacteria. Over time, the sensitivity and reproducibility of the technique has been improved. Usually, the number of...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.13.98

    authors: Edouard S,Raoult D

    更新日期:2013-10-01 00:00:00

  • Function of glutaredoxin 3 (Grx3) in oxidative stress response caused by iron homeostasis disorder in Candida albicans.

    abstract:AIM:Glutaredoxin is a conserved oxidoreductase in eukaryotes and prokaryotes. This study aimed to determine the role of Grx3 in cell survival, iron homeostasis and the oxidative stress response in Candida albicans. MATERIALS & METHODS:A grx3Δ/Δ mutant was obtained using PCR-mediated homologs recombination. The functio...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2017-0098

    authors: Zhang D,Dong Y,Yu Q,Kai Z,Zhang M,Jia C,Xiao C,Zhang B,Zhang B,Li M

    更新日期:2017-11-01 00:00:00

  • Clinical and molecular epidemiology of Acinetobacter baumannii bloodstream infections in an endemic setting.

    abstract:AIM:The transmission dynamics of Acinetobacter baumannii in endemic settings, and the relation between microbial properties and patients' clinical outcomes, are yet obscure and hampered by insufficient metadata. METHODS & RESULTS:Of 20 consecutive patients with A. baumannii bloodstream infection that were thoroughly a...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2016-0158

    authors: Marchaim D,Levit D,Zigron R,Gordon M,Lazarovitch T,Carrico JA,Chalifa-Caspi V,Moran-Gilad J

    更新日期:2017-03-01 00:00:00

  • Accurate differentiation of novel Staphylococcus argenteus from Staphylococcus aureus using MALDI-TOF MS.

    abstract:AIM:We evaluated a Staphylococcus argenteus-specific diagnostic profile of matrix-assisted laser desorption/ionization time-of-flight mass spectrometer for accurate identification of this novel bacterium. MATERIALS & METHODS:Staphylococcus argenteus was identified based on negative crtM gene and presence of specific s...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2018-0015

    authors: Chen SY,Lee H,Teng SH,Wang XM,Lee TF,Huang YC,Liao CH,Teng LJ,Hsueh PR

    更新日期:2018-07-01 00:00:00

  • γ-irradiation from radiotherapy improves the virulence potential of Candida tropicalis.

    abstract:AIM:To evaluate if radiation used in radiotherapy can cause changes in the virulence potential of Candida tropicalis ATCC 750. MATERIALS & METHODS:C. tropicalis was exposed in vitro to identical dose and scheme of irradiation would be used in patients with head and neck cancer. Some virulence parameters were analyzed ...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2017-0137

    authors: da Silva EM,Kischkel B,Shinobu-Mesquita CS,Bonfim-Mendonça PS,Mansano ES,da Silva MA,Barbosa JF,Fiorini A,Hernandes L,Furlaneto MC,Svidzinski TI

    更新日期:2017-12-01 00:00:00

  • Folate metabolism as a source of molecular targets for antimalarials.

    abstract::Folate metabolism of the malaria parasites provides two targets for current antimalarials: dihydrofolate reductase and dihydropteroate synthase. Dihydrofolate reductase inhibitors have been used as antimalarials over the past few decades, often in combination with dihydropteroate synthase inhibitors. Resistance to the...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/17460913.1.1.113

    authors: Yuthavong Y,Kamchonwongpaisan S,Leartsakulpanich U,Chitnumsub P

    更新日期:2006-06-01 00:00:00

  • Epigenetics in the unicellular parasite Entamoeba histolytica.

    abstract::Amoebiasis is a serious infectious disease that is caused by the unicellular parasite, Entamoeba histolytica. This parasite is mainly found in developing countries, and are named owing to its ability to destroy tissues. The molecular mechanisms that regulate the virulence of this parasite are not well understood. In r...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.10.140

    authors: Tovy A,Ankri S

    更新日期:2010-12-01 00:00:00

  • Oritavancin: a potential weapon in the battle against serious Gram-positive pathogens.

    abstract::Oritavancin is a lipoglycopeptide antibiotic with activity against aerobic and anaerobic Gram-positive bacteria. Oritavancin separates itself from other glycopeptides through its potent in vitro activity against resistant isolates of Staphylococcus aureus, Enterococcus spp. and Streptococcus spp. Oritavancin possesses...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/17460913.3.3.251

    authors: Crandon J,Nicolau DP

    更新日期:2008-06-01 00:00:00

  • The composition of intestinal microbiota and its association with functional constipation of the elderly patients.

    abstract::Aim: To identify intestinal microbiota compositions in elderly functional constipation (FC) patients. Materials & methods: Fecal samples from 61 FC patients and 48 healthy age-matched volunteers were analyzed through 16S rRNA gene sequencing. Results: The intestinal microbiota compositions of FC patients were signific...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2019-0283

    authors: Guo M,Yao J,Yang F,Liu W,Bai H,Ma J,Ma X,Zhang J,Fang Y,Miao Y,Sun J,Zhang Y,Zhao H

    更新日期:2020-02-01 00:00:00

  • Enterococcal endocarditis revisited.

    abstract::The Enterococcus species is the third main cause of infective endocarditis (IE) worldwide, and it is gaining relevance, especially among healthcare-associated cases. Patients with enterococcal IE are older and have more comorbidities than other types of IE. Classical treatment options are limited due to the emergence ...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.15.46

    authors: Pericás JM,Zboromyrska Y,Cervera C,Castañeda X,Almela M,Garcia-de-la-Maria C,Mestres C,Falces C,Quintana E,Ninot S,Llopis J,Marco F,Moreno A,Miró JM

    更新日期:2015-01-01 00:00:00

  • A novel triterpene from Astraeus hygrometricus induces reactive oxygen species leading to death in Leishmania donovani.

    abstract:AIM:The effect of astrakurkurone, a novel triterpene, isolated from Indian mushroom Astraeus hygrometricus has been investigated to elucidate the mechanisms involved in selective cell death of Leishmania donovani. MATERIALS & METHODS:The hypotheses were investigated using flow-cytometry, scanning electron microscopy a...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.14.149

    authors: Mallick S,Dey S,Mandal S,Dutta A,Mukherjee D,Biswas G,Chatterjee S,Mallick S,Lai TK,Acharya K,Pal C

    更新日期:2015-01-01 00:00:00

  • Genetic and population analyses of Vibrio parahaemolyticus isolates from three major coastal regions in China.

    abstract:AIM:This study aims to evaluate the genetic and population structure of Vibrio parahaemolyticus in the major coastal regions of China. MATERIALS & METHODS:Multilocus sequence typing was performed. RESULTS:Insertion of large sequence into recA happened in nearly 30 strains, which were untypeable by multilocus sequence...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2018-0060

    authors: Li P,Xin W,Kang L,Chen Z,Guo C,Gao S,Yang H,Ji B,Yan Y,Wang H,Zhou D,Yang W,Wang J

    更新日期:2018-09-01 00:00:00

  • Molecular phylogenetics and epidemiology of Candida albicans.

    abstract::Candida albicans, a diploid yeast commensal and opportunist pathogen, has evolved unusual mechanisms for maintenance of genetic diversity in the absence of a complete sexual cycle. These include chromosomal polymorphisms, mitotic recombination events, and gains and losses of heterozygosity, superimposed on a fundament...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.09.113

    authors: Odds FC

    更新日期:2010-01-01 00:00:00

  • Uncivil engineers: Chlamydia, Salmonella and Shigella alter cytoskeleton architecture to invade epithelial cells.

    abstract::The obligate intracellular bacterial pathogen Chlamydia trachomatis is a major cause of blindness and sexually transmitted diseases. Like the enteric pathogens Salmonella and Shigella, Chlamydia injects effector proteins into epithelial cells to initiate extensive remodeling of the actin cytoskeleton at the bacterial ...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.10.77

    authors: Dunn JD,Valdivia RH

    更新日期:2010-08-01 00:00:00