Abstract:
:Disruption of the plasma membrane poses deadly threat to eukaryotic cells and survival requires a rapid membrane repair system. Recent evidence reveal various plasma membrane repair mechanisms, which are required for cells to cope with membrane lesions including membrane fusion and replacement strategies, remodeling of cortical actin cytoskeleton and vesicle wound patching. Members of the annexin protein family, which are Ca2+-triggered phospholipid-binding proteins emerge as important components of the plasma membrane repair system. Here, we discuss the mechanisms of plasma membrane repair involving annexins spanning from yeast to human cancer cells.
journal_name
Biol Chemjournal_title
Biological chemistryauthors
Boye TL,Nylandsted Jdoi
10.1515/hsz-2016-0171subject
Has Abstractpub_date
2016-10-01 00:00:00pages
961-9issue
10eissn
1431-6730issn
1437-4315pii
/j/bchm.just-accepted/hsz-2016-0171/hsz-2016-0171.journal_volume
397pub_type
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