Factors associated with successful revascularization using the aspiration component of ADAPT in the treatment of acute ischemic stroke.

Abstract:

INTRODUCTION:ADAPT (a direct aspiration first pass technique) has been shown to be fast, cost-effective, and associated with excellent angiographic and clinical outcomes in the treatment of acute ischemic stroke (AIS). OBJECTIVE:To identify any and all preoperative factors that are associated with successful revascularization using aspiration alone. METHODS:A retrospective review of 76 patients with AIS treated with thrombectomy was carried out. Cohort 1 included cases in which aspiration alone was successful (Thrombolysis in Cerebral Infarction 2b or 3). Cohort 2 included cases in which aspiration was unsuccessful or could not be performed despite an attempt. RESULTS:There was no difference between cohorts in gender, race, medications, National Institute of Health Stroke Scale score, IV tissue plasminogen activator, site or side of the occlusion, dense vessel sign, aortic arch type, severe stenosis, clot length, operator years of experience, and guide/aspiration catheters used. Patients in cohort 1 were on average younger (66.5 vs 74.1 years, p=0.025). There was a trend for more patients in cohort 2 to have atrial fibrillation/arrhythmias (62.5% vs 45.5%, p=0.168) and have a cardiogenic stroke etiology (78.1% vs 56.8%, p=0.086). There was also a trend for more reverse curves (2.3 vs 1.7, p=0.107), larger vessel diameter (3.26 mm vs 2.88 mm, p=0.184), larger vessel-to-catheter ratio (2.09 vs 1.87, p=0.192), and worse clot burden score (5.38 vs 6.68, p=0.104) in cohort 2. CONCLUSIONS:Aspiration success was associated with younger age. Our findings suggest that ADAPT can be used for the vast majority of patients but it may be beneficial to use a different method first in the elderly.

journal_name

J Neurointerv Surg

authors

Mascitelli JR,Kellner CP,Oravec CS,De Leacy RA,Oermann EK,Yaeger K,Paramasivam S,Fifi JT,Mocco J

doi

10.1136/neurintsurg-2016-012439

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

636-640

issue

7

eissn

1759-8478

issn

1759-8486

pii

neurintsurg-2016-012439

journal_volume

9

pub_type

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