Abstract：
:With the great development of sequencing technologies and systematic methods, our understanding of evolutionary relationships at deeper levels within the tree of life has greatly improved over the last decade. However, the current taxonomic methodology is insufficient to describe the growing levels of diversity in both a standardised and general way due to the limitations of using only morphological traits to describe clades. Herein, we propose the idea of a molecular classification based on hierarchical and discrete amino acid characters. Clades are classified based on the results of phylogenetic analyses and described using amino acids with group specificity in phylograms. Practices based on the recently published phylogenomic datasets of insects together with 15 de novo sequenced transcriptomes in this study demonstrate that such a methodology can accommodate various higher ranks of taxonomy. Such an approach has the advantage of describing organisms in a standard and discrete way within a phylogenetic framework, thereby facilitating the recognition of clades from the view of the whole lineage, as indicated by PhyloCode. By combining identification keys and phylogenies, the molecular classification based on hierarchical and discrete characters may greatly boost the progress of integrative taxonomy.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Wu HY,Wang YH,Xie Q,Ke YL,Bu WJdoi
10.1038/srep28308subject
Has Abstractpub_date
2016-06-17 00:00:00pages
28308issn
2045-2322pii
srep28308journal_volume
6pub_type
杂志文章abstract：:The recent past has seen impressive progress in the treatment of various malignancies using immunotherapy. One of the most promising approaches involves immune checkpoint inhibitors. However, the clinical results with these agents have demonstrated variability in the response. Pancreatic cancer, in particular, has pro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41251-9
更新日期：2019-03-18 00:00:00
abstract：:In recent years, there has been an impressively fast technological progress in the development of highly efficient lead halide perovskite solar cells. However, the stability of perovskite films and respective solar cells is still an open point of concern and calls for advanced characterization methods. In this work, w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35973
更新日期：2016-10-27 00:00:00
abstract：:Cassava is an important staple crop in tropical and sub-tropical areas. As a common farming practice, cassava is usually cultivated intercropping with other crops and subjected to various degrees of shading, which causes reduced productivity. Herein, a comparative transcriptomic analysis was performed on a series of d...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31673
更新日期：2016-08-19 00:00:00
abstract：:We have investigated the valley Chern number and gapless edge states in wide-gap semiconductor SiC and BN monolayers by using the density functional theory calculations. We found that while SiC monolayer has a non-quantized valley Chern number due to a partial mixing of the Berry curvature peaks pertaining to the oppo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61906-2
更新日期：2020-03-19 00:00:00
abstract：:Few studies have investigated the relationship between chronic rhinosinusitis (CRS) and erectile dysfunction (ED). This case-control study aimed to investigate the association between CRS and the risk of ED in a large national sample. Tapping Taiwan's National Health Insurance Research Database, we identified people 3...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/srep32195
更新日期：2016-08-31 00:00:00
abstract：:Meromictic lakes are useful biogeochemical models because of their stratified chemical gradients and separation of redox reactions down the water column. Perennially ice-covered meromictic lakes are particularly stable, with long term constancy in their density profiles. Here we sampled Lake A, a deep meromictic lake ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00604
更新日期：2012-01-01 00:00:00
abstract：:Hair cortisol concentration (HCC) is a promising measure of long-term hypothalamus-pituitary-adrenal (HPA) axis activity. Previous research has suggested an association between HCC and psychological variables, and initial studies of inter-individual variance in HCC have implicated genetic factors. However, whether HCC...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-017-11852-3
更新日期：2017-11-10 00:00:00
abstract：:The accurate calculation of decimal fractions is still a challenge for the binary-coded computations that rely on von Neumann paradigm. Here, we report a kind of memristive abacus based on synaptic Ag-Ge-Se device, in which the memristive long-term potentiation and depression are caused by a chemically driven phase tr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01230
更新日期：2013-01-01 00:00:00
abstract：:Selective serotonin reuptake inhibitors are among the most prescribed antidepressants. Fluoxetine is the lead molecule which exerts its therapeutic effects, at least in part, by promoting neuroplasticity through increased brain-derived neurotrophic factor (BDNF)/tropomyosin-related receptor kinase B (TrkB) signalling....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42775-w
更新日期：2019-04-19 00:00:00
abstract：:Diatoms are among the most diverse eukaryotic microorganisms on Earth, they are responsible for a large fraction of primary production in the oceans and can be found in different habitats. Pseudo-nitzschia are marine planktonic diatoms responsible for blooms in coastal and oceanic waters. We analyzed the transcriptome...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12329
更新日期：2015-07-20 00:00:00
abstract：:In this work the chalcopyrite CuIn3Se5-xTex (x = 0~0.5) with space group through isoelectronic substitution of Te for Se have been prepared, and the crystal structure dilation has been observed with increasing Te content. This substitution allows the anion position displacement ∆u = 0.25-u to be zero at x ≈ 0.15. Howe...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40224
更新日期：2017-01-06 00:00:00
abstract：:Appropriate isolation methods are essential for unravelling the relative contribution of extracellular vesicles (EVs) and the EV-free secretome to homeostasis and disease. We hypothesized that ultrafiltration followed by size exclusion chromatography (UF-SEC) provides well-matched concentrates of EVs and free secreted...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15717-7
更新日期：2017-11-10 00:00:00
abstract：:Kashin-Beck disease (KBD) is a chronic osteoarthropathy, which manifests as joint deformities and growth retardation. Only a few genetic studies of growth retardation associated with the KBD have been carried out by now. In this study, we conducted a two-stage bivariate genome-wide association study (BGWAS) of the KBD...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31792
更新日期：2016-08-22 00:00:00
abstract：:Rice bacterial blight caused by Xanthomonas oryzae pv. oryzae (Xoo) is one of the most destructive rice diseases worldwide. Therefore, in addition to breeding disease-resistant rice cultivars, it is desirable to develop effective biocontrol agents against Xoo. Here, we report that a soil bacterium Pseudomonas taiwanen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32950
更新日期：2016-09-08 00:00:00
abstract：:Craniofacial muscles drive critical functions in the head, including speech, feeding and expression. Compared with their counterparts in trunk and limbs, craniofacial muscles are of distinct embryonic origins, which might consequently lead to different growth patterns and regenerative potential. In this study, rat lev...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28917-6
更新日期：2018-07-13 00:00:00
abstract：:Identifying how spatially distributed information becomes integrated in the brain is essential to understanding higher cognitive functions. Previous computational and empirical studies suggest a significant influence of brain network structure on brain network function. However, there have been few analytical approach...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep46606
更新日期：2017-04-20 00:00:00
abstract：:The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by neurons in the lateral hypothalamus and zona incerta. MCHergic neurons project throughout the central nervous system, indicating the involvements of many physiological functions, but the role in pain has yet to be determined. In thi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19145-z
更新日期：2018-01-15 00:00:00
abstract：:Part of the symptomatology of post-traumatic stress disorder (PTSD) are alterations in arousal and reactivity which could be related to a maladaptive increase in the automated sensory change detection system of the brain. In the current EEG study we investigated whether the brain's response to a simple auditory sensor...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16669-8
更新日期：2017-11-29 00:00:00
abstract：:Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of these lines with their other properties. The analysis revealed a r...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41241
更新日期：2017-01-25 00:00:00
abstract：:Mitochondrial dysfunction is implicated in many human diseases and occurs in normal aging. Mitochondrial health is maintained through organelle biogenesis and repair or turnover of existing mitochondria. Mitochondrial turnover is principally mediated by mitophagy, the trafficking of damaged mitochondria to lysosomes v...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12397
更新日期：2015-07-28 00:00:00
abstract：:Haber-Bosch nitrogen (N) has been increasingly used in industrial products, e.g., nylon, besides fertilizer. Massive numbers of species of industrial reactive N (Nr) have emerged and produced definite consequences but receive little notice. Based on a comprehensive inventory, we show that (1) the industrial N flux has...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02579
更新日期：2013-01-01 00:00:00
abstract：:The study was aimed to investigate the pathogens distribution and risk factors for PICC-related bloodstream infection in intensive care unit (ICU) patients. 402 patients placed with PICC in ICU were recruited in the study. The microbiological characteristics of PICC-related infection were investigated by Vitek 2 Compa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10037-2
更新日期：2017-11-08 00:00:00
abstract：:To assess the prevalence of cataract and cataract surgery in a population from Russia, we conducted the population-based Ural Eye and Medical Study with 5899 participants (80.5% out of 7328 eligible individuals), with an age of 40 + years as the eligibility criterion. In the phakic population, the prevalence of nuclea...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75313-0
更新日期：2020-10-23 00:00:00
abstract：:Patients with scirrhous gastric cancer (SGC) frequently develop peritoneal dissemination, which leads to poor prognosis. The secreted protein angiopoietin-like-4 (ANGPTL4), which is induced by hypoxia, exerts diverse effects on cancer progression. Here, we aimed to determine the biological function of ANGPTL4 in SGC c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11769-x
更新日期：2017-09-11 00:00:00
abstract：:Nowadays, increasing awareness of environment and fossil fuels protection stimulates intensive research on clean and renewable sources of energy. Production of hydrogen from water through solar-driven splitting reactions is one of the most promising approaches in the field of photoelectrochemistry (PEC). In this work ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-29247-3
更新日期：2018-07-18 00:00:00
abstract：:Accumulating evidence supports the polygenic nature of most complex diseases, suggesting the involvement of many susceptibility genes with small effect sizes. Although hundreds of genes may underlie the genetic architecture of complex diseases, those involved in a given disease are probably not randomly distributed, b...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33460
更新日期：2016-09-14 00:00:00
abstract：:The modifier protein, ubiquitin (Ub) regulates various cellular pathways by controlling the fate of substrates to which it is conjugated. Ub moieties are also conjugated to each other, forming chains of various topologies. In cells, poly-Ub is attached to proteins and also exists in unanchored form. Accumulation of un...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26364-x
更新日期：2018-05-31 00:00:00
abstract：:In this paper, we propose a real time, ultrahigh accuracy and full-field-of-view (RUF) algorithm for full field of view (FOV) imaging system. The proposed algorithm combines rough matching and precise matching method to stitch multiple images with the whole FOV in short time and high imaging quality. In order to verif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69353-9
更新日期：2020-07-24 00:00:00
abstract：:We report the experimental observation of extreme instabilities in a self-pulsing fiber laser under the influence of stimulated Brillouin scattering (SBS). Specifically, we observe temporally localized structures with high intensities that can be referred to as rogue events through their statistical behaviour with hig...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45868
更新日期：2017-04-04 00:00:00
abstract：:The chorioallantoic-membrane (CAM)-assay is an established model for in vivo tumor research. Contrary to rodent-xenograft-models, the CAM-assay does not require breeding of immunodeficient strains due to native immunodeficiency. This allows xenografts to grow on the non-innervated CAM without pain or impairment for th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75660-y
更新日期：2020-10-29 00:00:00
