Comparative transcriptomic analysis of human and Drosophila extracellular vesicles.

abstract：:High-throughput sequencing was applied to analyze the effects of toxic Microcystis aeruginosa on the silver carp Hypophthalmichthys molitrix. Silver carps were exposed to two cyanobacteria species (toxic and non-toxic) for RNA-seq and miRNA-seq analysis. RNA-seq revealed that the liver tissue contained 105,379 unigene...

journal_title：Scientific reports

authors： Hu M,Qu X,Pan L,Fu C,Jia P,Liu Q,Wang Y

更新日期：2017-09-05 00:00:00

abstract：:n-3 polyunsaturated fatty acids (PUFAs) and n-6 PUFAs are reported to have immunomodulatory effects, but few studies have examined these functions. Thus, we examined whether dietary n-3 and n-6 PUFAs are associated with the risk of gastric cancer and further investigated whether fatty acid desaturases 1 and 2 (FADS1 a...

journal_title：Scientific reports

authors： Lee S,Lee J,Choi IJ,Kim YW,Ryu KW,Kim YI,Kim J

更新日期：2018-02-28 00:00:00

abstract：:Globally, a small percentage of oil is recovered from reservoirs using primary and secondary recovery mechanisms, and thus a major focus of the oil industry is toward developing new technologies to increase recovery. Many new technologies utilize surfactants, macromolecules, and even nanoparticles, which are difficult...

journal_title：Scientific reports

authors： Eichmann SL,Burnham NA

更新日期：2017-09-14 00:00:00

abstract：:An understanding of load sharing among constituent phases aids in designing mechanical properties of multiphase materials. Here we investigate load partitioning between the body-centered-cubic iron matrix and NiAl-type precipitates in a ferritic alloy during uniaxial tensile tests at 364 and 506 °C on multiple length ...

journal_title：Scientific reports

authors： Sun Z,Song G,Sisneros TA,Clausen B,Pu C,Li L,Gao Y,Liaw PK

更新日期：2016-03-16 00:00:00

abstract：:Here, we present a fast mix-and-measure immunoassay for the specific semiquantitative detection of His-tagged proteins, for example in E. coli cell lysate. The assay is based on Förster resonance energy transfer (FRET) between a lanthanide dye-labeled low-affinity His-peptide and an acceptor-labeled anti-His-tag antib...

journal_title：Scientific reports

authors： Kreisig T,Prasse AA,Zscharnack K,Volke D,Zuchner T

更新日期：2014-07-08 00:00:00

abstract：:The neural substrates by which speech sounds are perceptually segregated into distinct streams are poorly understood. Here, we recorded high-density scalp event-related potentials (ERPs) while participants were presented with a cyclic pattern of three vowel sounds (/ee/-/ae/-/ee/). Each trial consisted of an adaptatio...

journal_title：Scientific reports

authors： Alain C,Arsenault JS,Garami L,Bidelman GM,Snyder JS

更新日期：2017-01-19 00:00:00

abstract：:Altered death receptor signaling and resistance to subsequent apoptosis is an important clinical resistance mechanism. Here, we investigated the role of death receptor resistance in breast cancer progression. Resistance of the estrogen receptor alpha (ER)-positive, chemosensitive MCF7 breast cancer cell line to tumor ...

journal_title：Scientific reports

authors： Antoon JW,Lai R,Struckhoff AP,Nitschke AM,Elliott S,Martin EC,Rhodes LV,Yoon NS,Salvo VA,Shan B,Beckman BS,Nephew KP,Burow ME

更新日期：2012-01-01 00:00:00

abstract：:Tyrosine kinase activity of the asymmetric EGFR homodimer is negatively regulated via ERK-mediated phosphorylation of Thr-669 in the juxtamembrane domain. In the present study, we investigated in human breast cancer cells whether a similar mechanism plays a role in the feedback regulation of the ErbB2/ErbB3 heterodime...

journal_title：Scientific reports

authors： Kawasaki Y,Sakimura A,Park CM,Tomaru R,Tanaka T,Ozawa T,Zhou Y,Narita K,Kishi H,Muraguchi A,Sakurai H

更新日期：2016-08-17 00:00:00

abstract：:Gram-positive bacteria homeostasis and antibiotic resistance mechanisms are dependent on the intricate architecture of the cell wall, where amidated peptidoglycan plays an important role. The amidation reaction is carried out by the bi-enzymatic complex MurT-GatD, for which biochemical and structural information is ve...

journal_title：Scientific reports

authors： Leisico F,V Vieira D,Figueiredo TA,Silva M,Cabrita EJ,Sobral RG,Ludovice AM,Trincão J,Romão MJ,de Lencastre H,Santos-Silva T

更新日期：2018-03-28 00:00:00

abstract：:A role of gut-brain axis emerges in the pathophysiology of anorexia nervosa and maintaining adapted physical activity during refeeding remains discussed. We aimed to assess gastrointestinal protein metabolism and investigate the contribution of physical activity during refeeding in C57BL/6 mice with activity-based ano...

journal_title：Scientific reports

authors： Achamrah N,Nobis S,Breton J,Jésus P,Belmonte L,Maurer B,Legrand R,Bôle-Feysot C,do Rego JL,Goichon A,Rego JC,Déchelotte P,Fetissov SO,Claeyssens S,Coëffier M

更新日期：2016-02-24 00:00:00

abstract：:Human listeners are able to recognize accurately an impressive range of complex sounds, such as musical instruments or voices. The underlying mechanisms are still poorly understood. Here, we aimed to characterize the processing time needed to recognize a natural sound. To do so, by analogy with the "rapid visual seque...

journal_title：Scientific reports

authors： Isnard V,Chastres V,Viaud-Delmon I,Suied C

更新日期：2019-05-29 00:00:00

abstract：:Sucralose is a widely-used artificial high-intensity sweetener. Although doubts have been raised about the safety of sucralose by several researchers, it can still be found in a broad range of foods and beverages worldwide, including in baked goods. Sucralose may decompose at high temperatures, and participate in chlo...

journal_title：Scientific reports

authors： Dong S,Liu G,Hu J,Zheng M

更新日期：2013-10-15 00:00:00

abstract：:Optical coherence tomography (OCT) is a valuable ancillary test in the diagnosis and management of chorioretinal disease. The evaluation of choroid thickness using OCT has become the focus of clinical applications. We report a linear artifact that acts as a confounding factor in choroidal thickness measurements by enh...

journal_title：Scientific reports

authors： Zuo C,Mi L,Yang S,Guo X,Xiao H,Liu X

更新日期：2017-08-16 00:00:00

abstract：:Fundamental cell signaling mechanisms that regulate dynamic remodeling of the extracellular matrix (ECM) in mechanically loaded tissues are not yet clearly understood. Trabecular meshwork (TM) tissue in the eye is under constant mechanical stress and continuous remodeling of ECM is crucial to maintain normal aqueous h...

journal_title：Scientific reports

authors： Tellios N,Belrose JC,Tokarewicz AC,Hutnik C,Liu H,Leask A,Motolko M,Iijima M,Parapuram SK

更新日期：2017-04-11 00:00:00

abstract：:Prosthesis embodiment, the perception of a prosthesis as part of one's body, may be an important component of functional recovery for individuals with upper limb absence. This work determined whether embodiment differs between body-powered and myoelectric prosthesis users. In a sample of nine individuals with transrad...

journal_title：Scientific reports

authors： Engdahl SM,Meehan SK,Gates DH

更新日期：2020-09-22 00:00:00

abstract：:Children with chronic kidney disease suffer from excessive cardiovascular mortality and early alterations of the cardiovascular system. Tissue doppler imaging is a validated echocardiographic tool to assess early systolic and diastolic cardiac dysfunction. We hypothesized that tissue Doppler velocities would reveal re...

journal_title：Scientific reports

authors： Doyon A,Haas P,Erdem S,Ranchin B,Kassai B,Mencarelli F,Lugani F,Harambat J,Matteucci MC,Chinali M,Habbig S,Zaloszyc A,Testa S,Vidal E,Gimpel C,Azukaitis K,Kovacevic A,Querfeld U,Schaefer F

更新日期：2019-08-07 00:00:00

abstract：:Mastery over the structure of nanoparticles might be an effective way to enhance their performance for a given application. Herein we demonstrate the design of cage-bell nanostructures to enhance the methanol tolerance of platinum (Pt) nanoparticles while remaining their catalytic activity for oxygen reduction reactio...

journal_title：Scientific reports

authors： Feng Y,Ye F,Liu H,Yang J

更新日期：2015-11-18 00:00:00

abstract：:Cross-polarization conversion plays an important role in visible light manipulation. Metasurface with asymmetric structure can be used to achieve polarization conversion of linearly polarized light. Based on this, we design a quasi-periodic dendritic metasurface model composed of asymmetric dendritic cells. The simula...

journal_title：Scientific reports

authors： Fang ZH,Chen H,An D,Luo CR,Zhao XP

更新日期：2018-06-26 00:00:00

abstract：:A number of studies have suggested that the irradiation behavior and damage processes occurring during sequential and simultaneous particle irradiations can significantly differ. Currently, there is no definite answer as to why and when such differences are seen. Additionally, the conventional multi-particle irradiati...

journal_title：Scientific reports

authors： Mir AH,Toulemonde M,Jegou C,Miro S,Serruys Y,Bouffard S,Peuget S

更新日期：2016-07-28 00:00:00

abstract：:Wolbachia, an endosymbiotic alpha-proteobacterium commonly found in insects, can inhibit the transmission of human pathogens by mosquitoes. Biocontrol programs are underway using Aedes aegypti mosquitoes trans-infected with a non-natural Wolbachia strain to reduce dengue virus transmission. Less is known about the imp...

journal_title：Scientific reports

authors： Straub TJ,Shaw WR,Marcenac P,Sawadogo SP,Dabiré RK,Diabaté A,Catteruccia F,Neafsey DE

更新日期：2020-08-14 00:00:00

abstract：:Osteogenesis imperfecta (OI), a congenital bone disorder, is caused by mutations in COL1A1 and COL1A2 genes, leading to deficiency of type I collagen. The high resolution melting (HRM) analysis has been used for detecting mutations, polymorphisms and epigenetic alteration in double-stranded DNAs. This study was to eva...

journal_title：Scientific reports

authors： Wang J,Ren X,Bai X,Zhang T,Wang Y,Li K,Li G

更新日期：2015-08-26 00:00:00

abstract：:Tropopause temperatures (TPTs) control the amount of stratospheric water vapour, which influences chemistry, radiation and circulation in the stratosphere, and is also an important driver of surface climate. Decadal variability and long-term trends in tropical TPTs as well as stratospheric water vapour are largely unk...

journal_title：Scientific reports

authors： Wang W,Matthes K,Omrani NE,Latif M

更新日期：2016-07-12 00:00:00

abstract：:Waves of any kinds, including sound waves and light waves, can interfere constructively or destructively when they are overlapped, allowing for myriad applications. However, unlike continuous waves of a single frequency, interference of photoacoustic pulses is often overlooked because of their broadband characteristic...

journal_title：Scientific reports

authors： Lee T,Li Q,Guo LJ

更新日期：2016-02-12 00:00:00

abstract：:Osteosarcoma (OS) is the most common bone tumor characterized with a high risk of amputation and malignant morbidity among teenagers and adolescents. However, relevant pathogenic/biological mechanisms underlying OS-genesis remains to be ambiguous. The aim of this study was to elucidate functional relationship about mi...

journal_title：Scientific reports

authors： Wang H,Tang M,Ou L,Hou M,Feng T,Huang YE,Jin Y,Zhang H,Zuo G

更新日期：2017-07-14 00:00:00

abstract：:For augmentation or reconstruction of urinary bladder after cystectomy, bladder urothelium derived from human induced pluripotent stem cells (hiPSCs) has recently received focus. However, previous studies have only shown the emergence of cells expressing some urothelial markers among derivatives of hiPSCs, and no repo...

journal_title：Scientific reports

authors： Suzuki K,Koyanagi-Aoi M,Uehara K,Hinata N,Fujisawa M,Aoi T

更新日期：2019-07-19 00:00:00

abstract：:Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. However, the TM4SF1-associated signaling network in metastasis remains unknown. In the present study, we found that TM4SF1 affected the format...

journal_title：Scientific reports

authors： Yang JC,Zhang Y,He SJ,Li MM,Cai XL,Wang H,Xu LM,Cao J

更新日期：2017-04-03 00:00:00

abstract：:Human NAD-dependent isocitrate dehydrogenase catalyzes the decarboxylation of isocitrate (ICT) into α-ketoglutarate in the Krebs cycle. It exists as the α2βγ heterotetramer composed of the αβ and αγ heterodimers. Previously, we have demonstrated biochemically that the α2βγ heterotetramer and αγ heterodimer can be allo...

journal_title：Scientific reports

authors： Ma T,Peng Y,Huang W,Ding J

更新日期：2017-01-18 00:00:00

abstract：:Although giant proximity effect (GPE) can shed important information on understanding superconducting pairing mechanisms and superconducting electronics, reports on the GPE are few because the fabrication of the junctions with GPE is technologically difficult. Here, we report a GPE in the single-crystalline MgB2 bilay...

journal_title：Scientific reports

authors： Jung SG,Pham D,Park TH,Choi HY,Seo JW,Kang WN,Park T

更新日期：2019-03-01 00:00:00

abstract：:Soybean is an important source of protein, oil and carbohydrates, as well as other beneficial nutrients. A major function of proteins in nutrition is to supply adequate amounts of amino acids. Although they are essential for human nutrition, the sulfur-containing amino acids cysteine (Cys) and methionine (Met) are oft...

journal_title：Scientific reports

authors： Malle S,Eskandari M,Morrison M,Belzile F

更新日期：2020-12-11 00:00:00

abstract：:Every day we are exposed to different ideas, or memes, competing with each other for our attention. Previous research explained popularity and persistence heterogeneity of memes by assuming them in competition for limited attention resources, distributed in a heterogeneous social network. Little has been said about wh...

journal_title：Scientific reports

authors： Coscia M

更新日期：2014-09-26 00:00:00