Abstract:
BACKGROUND:There is conflicting evidence regarding the oncological impact of anastomotic leak following colorectal cancer surgery. This study aims to test the hypothesis that anastomotic leak is independently associated with local recurrence and overall and cancer-specific survival. METHODS:Analysis of prospectively collected data from multiple centres in Victoria between 1988 and 2015 including all patients who underwent colon or rectal resection for cancer with anastomosis was presented. Overall and cancer-specific survival rates and rates of local recurrence were compared using Cox regression analysis. RESULTS:A total of 4892 patients were included, of which 2856 had completed 5-year follow-up. The overall anastomotic leak rate was 4.0%. Cox regression analysis accounting for differences in age, sex, body mass index, American Society of Anesthesiologists score and tumour stage demonstrated that anastomotic leak was associated with significantly worse 5-year overall survival (χ 2 = 6.459, P = 0.011) for colon cancer, but only if early deaths were included. There was no difference in 5-year colon cancer-specific survival (χ 2 = 0.582, P = 0.446) or local recurrence (χ 2 = 0.735, P = 0.391). For rectal cancer, there was no difference in 5-year overall survival (χ 2 = 0.266, P = 0.606), cancer-specific survival (χ 2 = 0.008, P = 0.928) or local recurrence (χ 2 = 2.192, P = 0.139). CONCLUSION:Anastomotic leak may reduce 5-year overall survival in colon cancer patients but does not appear to influence the 5-year overall survival in rectal cancer patients. There was no effect on local recurrence or cancer-specific survival.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Sammour T,Hayes IP,Jones IT,Steel MC,Faragher I,Gibbs Pdoi
10.1111/ans.13648subject
Has Abstractpub_date
2018-01-01 00:00:00pages
E6-E10issue
1-2eissn
1445-1433issn
1445-2197journal_volume
88pub_type
杂志文章abstract:INTRODUCTION:The purpose of the present paper is to provide geographically representative information on the presentation, treatment and complications of human bites of the hand in Australia. METHODS:A 5-year retrospective study was undertaken of patients treated at Royal Hobart Hospital for human bites of the hand. T...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1440-1622.2001.02162.x
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Many attempts have been made to determine ways of decreasing the negative laparotomy rate after a clinical diagnosis of acute appendicitis. The aim of the present study was to determine the effectiveness of serum interleukin-6 (IL-6) concentration in the diagnosis of appendicitis, and in the prevention of no...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2002.02516.x
更新日期:2002-09-01 00:00:00
abstract:BACKGROUNDS:Bowel cancer is the second most common non-cutaneous cancer diagnosed in Australia among both genders. Colonoscopy withdrawal time of at least 6 min has been accepted as the standard to achieve the target polyp detection rate (PDR) and adenoma detection rate (ADR). A retrospective review was conducted in Bu...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15652
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Surgical decision-making tools may help surgeons achieve better outcomes by providing more personally relevant information to patients. This paper describes approaches to developing statistical tools capable of estimating the probability of morbidity and mortality after cardiovascular surgery. Our aim is to ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2010.05644.x
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Many haemodialysis patients are unable to have or maintain distal upper limb arteriovenous (AV) fistulas because of inadequate veins or arteries and therefore require more proximal access. We have reviewed our experience with a two-stage brachiobasilic AV haemodialysis fistula fashioned in the arm. METHODS:...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03996.x
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Open cholecystectomy is still a fairly frequently performed operation worldwide, and is used where laparoscopic surgery has failed or is contraindicated, and where some surgeons do not operate laparoscopically for technical reasons. In developing countries laparoscopic cholecystectomy is costly and is availa...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1440-1622.2001.02046.x
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:A survey conducted in 1992 found that New Zealand orthopaedic surgeons relied on non-pharmacological methods of deep vein thrombosis prevention in most arthroplasty patients and almost all hip fracture patients. This survey was repeated in 1999 to ascertain whether this pattern of use had changed. METHODS:A...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2002.02404.x
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Sentinel node biopsy is an accurate method for staging the axilla in early (small) breast cancers. However, data for the role of this technique for large breast cancers remain limited. METHOD:From the Royal Adelaide Hospital Sentinel Node database and the SNAC trial database, 100 subjects were identified wi...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12139
更新日期:2014-03-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04651.x
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journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2011.05971.x
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:The correlation of post-operative serum albumin level with the occurrence of anastomotic leakage (AL) in oesophageal squamous cell carcinoma (ESCC) remains unclear. The aim of this study was to evaluate the impact of post-operative serum albumin level on AL after transthoracic oesophagectomy. METHODS:Patien...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.16406
更新日期:2020-11-05 00:00:00
abstract:BACKGROUND:Surgical approach into the fissural parenchyma may be an important and modifiable factor for the prevention of air leak after anatomical lung resections. Fissureless fissure-last technique has been described as useful technique to reduce air leak, yet in video-assisted thoracoscopic surgery (VATS) data are l...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13884
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:This study aims to assess the survival of patients who underwent peritonectomy, to assess the morbidity and mortality associated with the procedure and to review the published reports on the survival of patients with peritoneal spread of colorectal cancer (CRC). METHODS:Peritonectomy involves resection of a...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03749.x
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Solid pseudopapillary tumour of the pancreas is a rare pancreatic tumour that occurs predominantly in women, with very few cases reported in men. This is a tumour with low malignancy potential and surgical resection usually results in cure. METHODS:A retrospective review of our experience with solid pseudop...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2003.t01-1-02634.x
更新日期:2003-06-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1111/ans.12214
更新日期:2014-01-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2012.06262.x
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Various treatment measures have been described in achieving splenic preservation following splenic injury. We describe an additional measure in achieving haemostasis during mesh splenorrhaphy. METHODS:Oxycel (BD, Franklin Lakes, NJ, USA) (topical haemostatic agent composed of oxidized cellulose) is sutured ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2004.03065.x
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Re-bleeding after management of a first haemorrhage following pancreatic surgery is an ever-present danger and often presents diagnostic and management dilemmas. METHODS:All cases of post-pancreatectomy haemorrhage (PPH) following pancreatoduodenectomy were identified from a tertiary referral, clinical data...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13976
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:We assessed the accuracy of three different methods measuring the angle between two fixed Kirschner wires for the potential purpose of determining correction during rotational osteotomy of long bones. METHODS:Thirty-one orthopaedic consultants and registrars were prospectively asked to measure the angle bet...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12371
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:The 2009 American Thyroid Association (ATA) three-tiered risk stratification, and its updated version in 2015, provided clearer guidance on the use of radioactive iodine (RAI) ablation in differentiated thyroid cancer (DTC) patients. This study examines the impact of these guidelines on RAI use in our instit...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13851
更新日期:2018-04-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-1433.2003.02885.x
更新日期:2004-01-01 00:00:00
abstract::Currently in Australasia, concomitant cholecystolithiasis and choledocholithiasis are usually managed with two procedures: laparoscopic cholecystectomy (LC) and pre or postoperative endoscopic retrograde cholangiopancreatography (ERCP). This approach exposes the patient to the risk of complications from the common bil...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.13676
更新日期:2016-11-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03422.x
更新日期:2005-07-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-1433.2004.03136.x
更新日期:2004-09-01 00:00:00
abstract:INTRODUCTION:There are very little clinical and pathological data on colorectal cancer among Indigenous people in Australia. METHODS:A retrospective study on Indigenous patients treated for colorectal cancer at the Townsville and Cairns Base Hospitals from 1999 to 2004 was carried out in order to better characterise t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03592.x
更新日期:2005-11-01 00:00:00
abstract::Morgagni herniae are rare congenital diaphragmatic hernia, which normally present late in adult life with minimal symptoms. They are always associated with a peritoneal hernial sac, and often contain transverse colon or stomach. We present an unusual case of a Morgagni hernia containing caecum in an 81-year-old woman,...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2003.02745.x
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Previous studies have shown that children with isolated linear skull fractures have excellent clinical outcomes and low risk of surgery. We wish to identify other injury patterns within the spectrum of paediatric mild head injury, which need only conservative management. Children with low risk of evolving ne...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14175
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Telemedicine is a patient consultation method commonly available to patients in rural and remote areas throughout Australia. Its use in paediatric orthopaedics has been rarely described. The primary aim of this study was to identify the patient cohort accessing the orthopaedic paediatric telehealth service t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12753
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:An audit performed in the use of non-irradiated femoral head bone graft at the Geelong Hospital over a 10-year period. While it is thought the non-irradiated bone graft provides a better structural construct there is theoretical increased risk of infection transmission. METHODS:We performed a retrospective ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04800.x
更新日期:2009-01-01 00:00:00