Abstract：
:We have been made aware that text, figures and experimental data reported in the title paper [1] are duplicated in another publication by Zihan Xu et al. [2].[...].
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
International Journal Of Molecular Sciences Editorial Officedoi
10.3390/ijms17050768subject
Has Abstractpub_date
2016-05-20 00:00:00issue
5issn
1422-0067pii
ijms17050768journal_volume
17pub_type
杂志文章,撤回出版物abstract：:Poly(ADP-ribose)polymerase-1 (PARP1) is a nuclear protein implicated in DNA repair, recombination, replication, and chromatin remodeling. The aim of this study was to evaluate possible differences between PARP1(-/-) and wild-type mice regarding induction and repair of DNA lesions in irradiated male germ cells. Comet a...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms140918078
更新日期：2013-09-04 00:00:00
abstract：:The mitogen-activated protein kinase-activated protein kinase MK5 is a substrate of the mitogen-activated protein kinases p38, ERK3 and ERK4. Cell culture and animal studies have demonstrated that MK5 is involved in tumour suppression and promotion, embryogenesis, anxiety, cell motility and cell cycle regulation. In t...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms15034878
更新日期：2014-03-19 00:00:00
abstract：:Despite improvements in diagnosis and treatment, breast cancer is still the most common cancer type among non-smoking females. TGF-β can inhibit breast cancer development by inducing cell cycle arrest in both, cancer cells and, as part of a senescence program in normal human mammary epithelial cells (HMEC). Moreover, ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms18071574
更新日期：2017-07-20 00:00:00
abstract：:Breast (BCa) and gynecological (GCa) cancers constitute a group of female neoplasms that has a worldwide significant contribution to cancer morbidity and mortality. Evidence suggests that polymorphisms influencing miRNA function can provide useful information towards predicting the risk of female neoplasms. Inconsiste...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,meta分析
doi：10.3390/ijms20205088
更新日期：2019-10-14 00:00:00
abstract：:Fetal programming implies that the maternal diet during pregnancy affects the long-term health of offspring. Although maternal diet influences metabolic disorders and non-alcoholic fatty liver disease in offspring, the hepatic mechanisms related to metabolites are still unknown. Here, we investigated the maternal diet...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21239060
更新日期：2020-11-28 00:00:00
abstract：:The At-Hook Motif Nuclear Localized Protein (AHL) gene family encodes embryophyte-specific nuclear proteins with DNA binding activity. They modulate gene expression and affect various developmental processes in plants. We identify AHL18 (At3G60870) as a developmental modulator of root system architecture and growth. A...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21051886
更新日期：2020-03-10 00:00:00
abstract：:The genetic basis of the wide variation for nutritional traits in Brassica rapa is largely unknown. A new Recombinant Inbred Line (RIL) population was profiled using High Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) analysis to detect quantitative trait loci (QTLs) controlling seed toc...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms140815561
更新日期：2013-07-25 00:00:00
abstract：:Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted increasing attention in many biomedical fields. In magnetic drug targeting SPIONs are injected into a tumour supplying artery and accumulated inside the tumour with a magnet. The effectiveness of this therapy is thus dependent on magnetic properties, s...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms16059368
更新日期：2015-04-24 00:00:00
abstract：:Spätzle family proteins activate the Toll pathway and induce antimicrobial peptide (AMP) production against microbial infections. However, the functional importance of Tmspätzle4 (TmSpz4) in the immune response of Tenebrio molitor has not been reported. Therefore, here, we have identified and functionally characterize...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21051878
更新日期：2020-03-09 00:00:00
abstract：:Metacaspases, a class of cysteine-dependent proteases like caspases in animals, are important regulators of programmed cell death (PCD) during development and stress responses in plants. The present study was focused on comprehensive analyses of expression patterns of the rice metacaspase (OsMC) genes in response to a...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms160716216
更新日期：2015-07-17 00:00:00
abstract：:Fetuin-A is the protein product of the AHSG gene in humans. It is mainly synthesized by the liver in adult humans and is secreted into the blood where its concentration can vary from a low of ~0.2 mg/mL to a high of ~0.8 mg/mL. Presently, it is considered to be a multifunctional protein that plays important roles in d...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms19082211
更新日期：2018-07-29 00:00:00
abstract：:Previous studies have demonstrated that microgravity could lead to health risks. The investigation of the molecular mechanisms from the aspect of systems biology has not been performed yet. Here, we integratively analyzed transcriptional and post-transcriptional regulations based on gene and miRNA expression profiles ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21207585
更新日期：2020-10-14 00:00:00
abstract：:Both positive and negative aspects of sport performance are currently considered. The aim of our study was to determine time- and intensity-dependent effects of a single exercise bout on redox and inflammatory status. The experiment was performed on 40 male Wistar rats subjected to treadmill running for 30 min with th...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21218071
更新日期：2020-10-29 00:00:00
abstract：:Osteosarcoma is the most common primary malignant bone tumour in children and adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure. Introduction of combination chemotherapy in the 1970s, however, dramatically increased overall survival rates from 20% to approximately 70%. Unfortunat...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms21186885
更新日期：2020-09-19 00:00:00
abstract：:Poly(glutamic acid) has been studied with a nanosecond T-jump experiment. A new experimental set-up based on the frequency-quadrupling of an 82 MHz Titanium-Sapphire laser allows rapid CD measurements to be performed. Combining time-resolved absorption and circular dichroism at 204 and 220 nm, we are able to measure p...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms13022239
更新日期：2012-01-01 00:00:00
abstract：:Bacillus cereus can survive in the form of spores for prolonged periods posing a serious problem for the manufacture of safe shelf-stable foods of optimal quality. Our study aims at increasing knowledge of B. cereus spores focusing primarily on germination mechanisms to develop novel milder food preservation strategie...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21155198
更新日期：2020-07-22 00:00:00
abstract：:Pre-mRNA splicing is an essential mechanism for ensuring integrity of the transcriptome in eukaryotes. Therefore, splicing deficiency might cause a decrease in functional proteins and the production of nonfunctional, aberrant proteins. To prevent the production of such aberrant proteins, eukaryotic cells have several ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21228799
更新日期：2020-11-20 00:00:00
abstract：:Duloxetine (DLX) is a potent drug investigated for the treatment of depression and urinary incontinence. DLX is extensively metabolized in the liver by two P450 isozymes, CYP2D6 and CYP1A2. Propolis (PPL) is one of the popular functional foods known to have effects on activities of CYPs, including CYP1A2. Due to the h...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21051862
更新日期：2020-03-09 00:00:00
abstract：:The lack of effective Alzheimer's disease treatment is becoming a challenge for researchers and prompts numerous attempts to search for and develop better therapeutic solutions. Compounds that affect several routes of the neurodegeneration cascade leading to the development of disease are of particular interest. An ex...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21082749
更新日期：2020-04-15 00:00:00
abstract：:Plants have been interacting with insects for several hundred million years, leading to complex defense approaches against various insect feeding strategies. Some defenses are constitutive while others are induced, although the insecticidal defense compound or protein classes are often similar. Insect herbivory induce...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms140510242
更新日期：2013-05-16 00:00:00
abstract：:Structural alterations of pericytes in microvessels are important features of diabetic retinopathy. Although capillary pericytes had been known not to have α-smooth muscle actin (αSMA), a recent study revealed that a specific fixation method enabled the visualization of αSMA along retinal capillaries. In this study, w...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21062158
更新日期：2020-03-20 00:00:00
abstract：:The analgesic effect of venlafaxine (VLX), which is a selective serotonin and noradrenaline reuptake inhibitor (SNRI), has been observed on oxaliplatin-induced neuropathic pain in mice. Significant allodynia was shown after oxaliplatin treatment (6 mg/kg, i.p.); acetone and von Frey hair tests were used to assess cold...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20071652
更新日期：2019-04-03 00:00:00
abstract：:Chlorogenic acid (CGA) decreases colon cancer-cell proliferation but the combined anti-cancer effects of CGA with its major colonic microbial metabolites, caffeic acid (CA), 3-phenylpropionic acid (3-PPA) and benzoic acid (BA), needs elucidation as they occur together in colonic digesta. Caco-2 cancer cells were treat...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19030723
更新日期：2018-03-03 00:00:00
abstract：:Interleukin-18 (IL-18) is a multi-functional immuno-mediator in the development and progression of many types of infectious and inflammatory diseases. In this study, we evaluated the contribution of IL-18 genotypes to renal cell carcinoma (RCC) in Taiwan via the genotyping of IL-18 -656 (A/C), -607 (A/C), and -137 (G/...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20071563
更新日期：2019-03-28 00:00:00
abstract：:Bovine immunoglobulin G (bIgG) was previously shown to enhance innate immune responses to toll-like receptor (TLR) stimulation, via induction of trained immunity. In this study, we investigated whether minimally processed dairy streams with high levels of whey proteins as potential infant nutrition ingredients could a...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21239077
更新日期：2020-11-28 00:00:00
abstract：:The term "pharmacological chaperone" was introduced 20 years ago. Since then the approach with this type of drug has been proposed for several diseases, lysosomal storage disorders representing the most popular targets. The hallmark of a pharmacological chaperone is its ability to bind a protein specifically and stabi...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms21020489
更新日期：2020-01-13 00:00:00
abstract：:Evaluation of relationships between molecular modeling structural parameters and high-performance liquid chromatography (HPLC) retention data of 11 cardiovascular system drugs by principal component analysis (PCA) in relation to their pharmacological activity was performed. The six retention data parameters were deter...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms11072681
更新日期：2010-07-09 00:00:00
abstract：:Although poly(2-hydroxyethyl methacrylate) (pHEMA) and polyethylene glycol methacrylate (PEGMA) have been demonstrated to inhibit bacterial adhesion, no study has compared antibacterial adhesion when salivary pellicle is coated on polymethyl methacrylate (PMMA) grafted with pHEMA and on PMMA grafted with PEGMA. In thi...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19092764
更新日期：2018-09-14 00:00:00
abstract：:Updated measurements of charged particle fluxes during the transit from Earth to Mars as well as on site measurements by Curiosity of Martian surface radiation fluxes identified potential health hazards associated with radiation exposure for human space missions. Designing mitigation strategies of radiation risks to a...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20010176
更新日期：2019-01-05 00:00:00
abstract：:Stem/progenitor cells are promising candidates for the regeneration of parenchyma in acute and chronic renal failure. However, recent data exhibit that survival of stem/progenitor cells after implantation in diseased renal parenchyma is restricted. To elaborate basic parameters improving survival, cell seeding was sim...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms151223240
更新日期：2014-12-15 00:00:00
