Abstract：
:Antineoplastic drugs used in chemotherapy were detected in aquatic environment: despite the very low concentrations (ng L(-1) to ug L(-1)), due to their potent mechanism of action they could have adverse effects on non-target aquatic organisms particularly under chronic exposure. Cisplatin (CDDP) is one of the most effective anticancer drug currently in use but information on its ecotoxicological effects is very limited. In this study, Mytilus galloprovincialis was used to investigate the toxic effects related to CDDP exposure. Mussels were exposed to cisplatin (100 ng L(-1)) for 14 days: antioxidant (superoxide dismutase, catalase, total and selenium-dependent glutathione peroxidase) and phase II (glutathione-S-transferase) enzymes activities, oxidative damage (lipid peroxidation), genotoxicity (DNA damage) and neurotoxicity (acetylcholinesterase) was evaluated. Results indicate that CDDP at tested concentration induce changes in the antioxidant capacity, oxidative stress in target organs (digestive gland and gills) as well as DNA damage in mussel hemocytes and neurotoxicity representing a risk for non-target organisms.
journal_name
Mar Environ Resjournal_title
Marine environmental researchauthors
Trombini C,Garcia da Fonseca T,Morais M,Rocha TL,Blasco J,Bebianno MJdoi
10.1016/j.marenvres.2016.05.004subject
Has Abstractpub_date
2016-08-01 00:00:00pages
12-21eissn
0141-1136issn
1879-0291pii
S0141-1136(16)30065-4journal_volume
119pub_type
杂志文章abstract：:Oil pollution of the oceans has been a problem ever since man began to use fossil fuels. Biodegradation by naturally occurring populations of micro-organisms is a major mechanism for the removal of petroleum from the environment. To examine the effects of crude oil pollution on intertidal bacteria, we repeated the sam...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(99)00080-x
更新日期：2000-06-01 00:00:00
abstract：:Halogenated aromatic hydrocarbons (HAHs) and polynuclear aromatic hydrocarbons (PAHs) are major environmental contaminants. Fish species that are chronically exposed to these compounds can develop resistance to their toxic effects. In all fish species studied to date, toxicant resistance has been accompanied by decrea...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(02)00184-8
更新日期：2002-09-01 00:00:00
abstract：:As part of an effort to validate the use of heat shock proteins (hsp) as a biomarker of adverse effect, we investigated the impact of estrogen (E2), the hormone responsible for vitellogenisis in fish, on the induction of hsp 60 and 70. PLHC-1 (Pociliopsis lucida hepatoma cell line) cells were cultured under standard c...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00130-6
更新日期：2000-07-01 00:00:00
abstract：:Nematode species composition, trophic structure and body size distributions were followed over an annual production cycle in the central North Sea; to test responses to temporally changing food quality and quantity in the sediment. Changes in the phytoplankton concentration in the water column were quantitatively refl...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2008.08.004
更新日期：2008-12-01 00:00:00
abstract：:The modulations of reproductive biomarker responses, such as vitellogenin (Vtg) and zona radiata protein (Zr-protein) by xenoestrogens are mediated through the estrogen receptors (ERs). The ERalpha and ERbeta belong to the nuclear receptor (NR) superfamily of ligand activated transcription factors that modulate specif...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2006.04.005
更新日期：2006-07-01 00:00:00
abstract：:Nonylphenol (NP) is a breakdown product of alkylphenol polyethoxylates (APEs), an important class of non-ionic surfactants that are widely used in many detergent formulations and plastic products for industrial and domestic use. A complex microbial degradation pattern, characterized by the formation of several metabol...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00081-7
更新日期：2000-07-01 00:00:00
abstract：:The sublethal effects of stormwater runoff from sections of a plum orchard treated with esfenvalerate or diazinon were evaluated in 7-day-old Sacramento splittail (Pogonichthys macrolepidotus) larvae. Fish were exposed to eight runoff samples using the USEPA standard static renewal method for 96 h acute toxicity testi...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2003.12.005
更新日期：2005-04-01 00:00:00
abstract：:Variability in levels and sources of polycyclic aromatic hydrocarbons (PAH) in sediments from one large sea area off the coast of northern Norway ("North area", NA) have been compared to similar data from another large area off the coast of southern Norway ("South area", SA). Samples from NA were collected at the Norw...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2013.03.006
更新日期：2013-06-01 00:00:00
abstract：:Field concentrations of polychlorinated biphenyls (PCBs) were measured in sediment and nine marine soft bottom invertebrate species. Lipid- and organic carbon normalised biota-sediment accumulation factors (BSAFs) were determined for 29 nonplanar and 11 coplanar congeners. To investigate whether the bioaccumulation wa...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2005.11.004
更新日期：2006-05-01 00:00:00
abstract：:The development of rapid and sensitive diagnostic tools to assess the effect of stressors on organisms is a principal objective of environmental proteomics. This study is focused on evaluating the potential of using surface-enhanced laser desorption/ionisation time-of-flight mass spectrometry (SELDI-TOF MS) to assess ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2006.04.002
更新日期：2006-07-01 00:00:00
abstract：:Fourteen trace elements (Ag, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se, V, and Zn) were analyzed in livers and muscles from 22 fish species from the New Caledonia lagoon, which is subjected to important chemical inputs due to intense land-based mining activities (New Caledonia is the third largest world producer of N...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2013.03.001
更新日期：2013-06-01 00:00:00
abstract：:The option of storing CO(2) in subsea rock formations to mitigate future increases in atmospheric CO(2) may induce problems for animals in the deep sea. In the present study the deep-sea bivalve Acesta excavata was subjected to environmental hypercapnia (pHSW 6.35, P(CO₂) =33,000 μatm) corresponding to conditions repo...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2011.07.002
更新日期：2011-09-01 00:00:00
abstract：:This paper examines the potential availability to a demersal fish of cadmium and zinc associated with digested sewage sludge, via a food chain as well as directly from the sludge, and the tissue distribution and possible excretion of any accumulated cadmium and zinc. Radioactive tracer techniques were used in order to...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00249-x
更新日期：2001-06-01 00:00:00
abstract：:Southern hemisphere humpback whales have evolved energetically demanding capital breeding and migratory life-history behaviours. It has been hypothesised that not all individuals of a population participate in the seasonal migration each year, or only undertake partial migrations. Given the cost of migration and repro...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2019.104749
更新日期：2019-10-01 00:00:00
abstract：:Spatial variations in dimethylsulfide (DMS) and dimethylsulfoniopropionate (DMSP) were surveyed in the surface microlayer and in the subsurface waters of the low productivity South China Sea in May 2005. Overall, average subsurface water concentrations of DMS and DMSP of dissolved (DMSPd) and particulate (DMSPp) fract...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2007.09.002
更新日期：2008-02-01 00:00:00
abstract：:The environmental DNA (eDNA) metabarcoding represents a new promising tool for biomonitoring and environmental impact assessment. One of the main advantages of eDNA metabarcoding, compared to the traditional morphotaxonomy-based methods, is to provide a more holistic biodiversity information that includes inconspicuou...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2018.12.009
更新日期：2019-04-01 00:00:00
abstract：:Immunohistochemical localization of enzymes is compared directly with localization of enzyme activity with (catalytic) enzyme histochemical methods. The two approaches demonstrate principally different aspects of an enzyme. The immunohistochemical method localizes the enzyme protein whether it is active or not whereas...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(02)00169-1
更新日期：2002-09-01 00:00:00
abstract：:The estuarine dynamics favoring the coexistence of mangroves, seagrass and corals at small river mouths are often poorly understood. We characterize the tidal, day/night and rainfall-induced short-term dynamics in salinity, pH, dissolved oxygen (DO), chlorophyll a (chl a), total suspended matter (TSM), water transpare...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2012.09.002
更新日期：2012-12-01 00:00:00
abstract：:Polycyclic aromatic hydrocarbons (PAH) were measured in sediment cores from 13 locations in South-Western Barents Sea as part of a detailed study of the Norwegian seabed under the MAREANO program. The generally low PAH levels found, an average around 200 ng g(-1) dry weight for sum PAH, indicate low inputs of petroleu...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2009.06.013
更新日期：2009-12-01 00:00:00
abstract：:The effects of a simulated spill of sunflower oil in salt marsh sediments were compared with an experiment with linseed oil. Sunflower and linseed oil penetrated the sediments at the same rates but different adsorption of the oils onto sediment particles resulted in the establishment of anaerobic conditions at shallow...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/S0141-1136(02)00309-4
更新日期：2003-09-01 00:00:00
abstract：:DNA single-strand breaks were measured by the comet assay in both gill and hemolymph cells of mussels collected in 3 sampling areas of the French coast (Pointe du Castelli, Pen Bron and Saint-Nazaire Harbour). Whole mussel tissue samples were also collected for the chemical determination of PAH, PCB and heavy metal co...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2004.03.090
更新日期：2004-08-01 00:00:00
abstract：:In this study we examined the effect of: observer presence; observer speed; and the impact that multiple surveys had on the number of counted fish in a visual census survey in a typical Mediterranean rocky habitat. SCUBA observer presence had no influence on the number of fish per survey. An improvement in the methodo...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/s0141-1136(00)00028-3
更新日期：2001-02-01 00:00:00
abstract：:Physiological tolerances limit the distribution of marine species, with geographical ranges being set by environmental factors, such as temperature and salinity, which affect the rates of vital processes and survival of marine ectotherms. The physiological tolerances of the non-native marine amphipod Caprella mutica w...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2007.02.003
更新日期：2007-09-01 00:00:00
abstract：:The fin whale (Balaenoptera physalus) is the most abundant and widespread mysticete species in the Mediterranean Sea, found mostly in deep, offshore waters of the western and central portion of the region. In the Mediterranean, this species is known to feed mainly on krill, in contrast to its Atlantic counterpart, whi...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2017.03.009
更新日期：2017-06-01 00:00:00
abstract：:Spatial and temporal increases of hypoxia in estuaries are of major environmental concern. Since mitochondria consume most of the oxygen in the cell, we examined the potential role of mitochondrial gene and protein expression in adaptation to chronic hypoxia in the grass shrimp Palaemonetes pugio. Grass shrimp were ex...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2008.02.046
更新日期：2008-07-01 00:00:00
abstract：:In this study, the seasonal variations in the morphometric features and in the cellular and biochemical parameters of the haemolymph were investigated in both male and female crabs (Carcinus aestuarii). Crabs were seasonally (November 2010-August 2011) collected from the Lagoon of Venice, and the moult stage, weight, ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2013.04.007
更新日期：2013-08-01 00:00:00
abstract：:Spatiotemporal environmental variation affects fish feeding behaviour and capacity for piscivorous control of prey populations, which is important for management when prey include invasive species causing ecosystem impacts. We assessed gut-contents of an important piscivore (European perch Perca fluviatilis) over two ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2017.10.017
更新日期：2017-12-01 00:00:00
abstract：:Identifying and quantifying microplastic in marine samples can be facilitated by removing natural organic matter (NOM). Cellulosic material, like chitin, however, are a type of NOM that is resistant to chemical digestion, and difficult to eliminate from samples. To address this, a two-step digestion method was develop...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.105080
更新日期：2020-10-01 00:00:00
abstract：:Oysters from the Pacific north-west coast contain high cadmium concentrations (greater than 13.5 microg g(-1) dry weight), which exceed consumer guidelines for international markets. Oysters are selective filter-feeders and attempts which have focused on suspended particulate matter (SPM) as a means to assess the impo...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2009.04.008
更新日期：2009-09-01 00:00:00
abstract：:Marine pollution due to disused industrial activities is a major threat to ecosystems and human health, for example through the effects of re-suspension of toxic substances that are present in contaminated sediments. Here, we examined the effects of different re-suspension patterns of polluted sediments from the site ...
journal_title：Marine environmental research
pub_type： 杂志文章
doi：10.1016/j.marenvres.2020.104978
更新日期：2020-09-01 00:00:00
