Abstract：
:The insula is a region that integrates interoception and drug urges, but little is known about its role in behavioral addiction such as internet addiction. We investigated insula-based functional connectivity in participants with internet gaming disorder (IGD) and healthy controls (HC) using resting-state functional MRI. The right and left insula subregions (posterior, ventroanterior, and dorsoanterior) were used as seed regions in a connectivity analysis. Compared with the HC group, the IGD group showed decreased functional connectivity between left posterior insula and bilateral supplementary motor area and middle cingulated cortex, between right posterior insula and right superior frontal gyrus, and decreased functional integration between insular subregions. The finding of reduced functional connectivity between the interoception and the motor/executive control regions is interpreted to reflect reduced ability to inhibit motor responses to internet gaming or diminished executive control over craving for internet gaming in IGD. The results support the hypothesis that IGD is associated with altered insula-based network, similar to substance addiction such as smoking.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Zhang Y,Mei W,Zhang JX,Wu Q,Zhang Wdoi
10.1007/s00221-016-4659-8subject
Has Abstractpub_date
2016-09-01 00:00:00pages
2553-60issue
9eissn
0014-4819issn
1432-1106pii
10.1007/s00221-016-4659-8journal_volume
234pub_type
杂志文章abstract：:The saccadic system has been traditionally regarded as two-dimensional (horizontal, vertical) and basically conjugate in the two eyes. However, saccades to disparate targets (e.g., targets in real three-dimensional space that are located in different directions and at different distances) are naturally disconjugate. W...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s002210050529
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journal_title：Experimental brain research
pub_type： 杂志文章
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230025
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1698-8
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
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更新日期：2012-04-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：2001-02-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00253624
更新日期：1989-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2966-7
更新日期：2012-02-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1602-6
更新日期：2003-12-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1461-1
更新日期：2003-08-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3491-7
更新日期：2013-06-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227640
更新日期：1996-11-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3728-5
更新日期：2014-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237590
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：1987-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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journal_title：Experimental brain research
pub_type： 杂志文章,评审
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：1998-02-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Experimental brain research
pub_type： 杂志文章
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235825
更新日期：1984-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235821
更新日期：1984-01-01 00:00:00
abstract：:Deep brain stimulation of the subthalamic nucleus (STN DBS) significantly improves clinical motor symptoms, as well as intensive aspects of movement like velocity and amplitude in patients with Parkinson's disease (PD). However, the effects of bilateral STN DBS on integrative and coordinative aspects of motor control ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5197-3
更新日期：2018-04-01 00:00:00
