Proteome analysis identifies L1CAM/CD171 and DPP4/CD26 as novel markers of human skin mast cells.

abstract：:A one-day intensive educational course on allergy and immunology theory and diagnostic procedure significantly increased the competency of allergy and immunology fellows-in-training. ...

journal_title：Allergy

authors： Elizalde A,Perez EE,Sriaroon P,Nguyen D,Lockey RF,Dorsey MJ

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Anaphylaxis to insect venom (Hymenoptera) is most severe in patients with mastocytosis and may even lead to death. However, not all patients with mastocytosis suffer from anaphylaxis. The aim of the study was to analyze differences in gene expression between patients with indolent systemic mastocytosis (ISM)...

journal_title：Allergy

authors： Niedoszytko M,Bruinenberg M,van Doormaal JJ,de Monchy JG,Nedoszytko B,Koppelman GH,Nawijn MC,Wijmenga C,Jassem E,Elberink JN

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:A favorable outcome of anaphylaxis depends on the rapidity of adequate initial management and epinephrine injection. However, few data on the management of anaphylactic reactions are available. The aim of this study was to investigate the management and awareness of anaphylaxis to foods by mean of an Interne...

journal_title：Allergy

authors： Eigenmann PA,Pastore FD,Zamora SA

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Characterization of uncontrolled asthma burden in a natural treatment setting can influence treatment recommendations and clinical practice. The objective was to characterize and compare the economic burden of severe or difficult-to-treat asthma in uncontrolled and controlled patients. METHODS:Baseline pati...

journal_title：Allergy

authors： Sullivan SD,Rasouliyan L,Russo PA,Kamath T,Chipps BE,TENOR Study Group.

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Allergic asthma is associated with airway inflammation and dysfunction of pulmonary surfactant. Because surfactant proteins (SP) account for immunomodulatory functions as well as biophysical functions, we hypothesized that the allergic response in asthma might be accompanied by a dysregulation of SPs. METHO...

journal_title：Allergy

authors： Erpenbeck VJ,Schmidt R,Günther A,Krug N,Hohlfeld JM

更新日期：2006-05-01 00:00:00

abstract：:The care of patients with difficult-to-control asthma ("difficult asthma") is challenging and costly. Despite high-intensity asthma treatment, these patients experience poor asthma control and face the greatest risk of asthma morbidity and mortality. Poor asthma control is often driven by severe asthma biology, which ...

journal_title：Allergy

authors： Tay TR,Hew M

更新日期：2018-07-01 00:00:00

abstract：:Allergic bronchopulmonary aspergillosis (ABPA) occurs in nonimmunocompromised patients and belongs to the hypersensitivity disorders induced by Aspergillus. Genetic factors and activation of bronchial epithelial cells in asthma or cystic fibrosis are responsible for the development of a CD(4)+Th2 lymphocyte activation...

journal_title：Allergy

authors： Tillie-Leblond I,Tonnel AB

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Allergic asthma is a multifactorial and probably multigenic inflammatory disease of the upper airways, and has been associated with the HLA class II alleles DR4 and DR7. Here we investigated possible associations with other polymorphic susceptibility/resistance genes located within the major histocompatibili...

journal_title：Allergy

authors： Aron Y,Busson M,Polla BS,Dusser D,Lockhart A,Swierczewski E,Favatier F

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Recurrent angioedema (RecA) is a frequent clinical problem characterized by suddenly occurring cutaneous and/or mucosal swellings. Depending on their location, RecA may be painful, hindering, disfiguring, or even life-threatening. The assessment of disease activity in affected patients is important to guide ...

journal_title：Allergy

authors： Weller K,Groffik A,Magerl M,Tohme N,Martus P,Krause K,Metz M,Staubach P,Maurer M

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:The role of arachidonic acid metabolites in NSAID-induced hypersensitivity has been studied in depth for NSAID-exacerbated respiratory disease (NERD) and NSAID-exacerbated cutaneous disease (NECD). However, no information is available for NSAID-induced urticarial/angioedema (NIUA), despite it being the most ...

journal_title：Allergy

authors： Doña I,Jurado-Escobar R,Perkins JR,Ayuso P,Plaza-Serón MC,Pérez-Sánchez N,Campo P,Bogas-Herrera G,Bartra J,Torres MJ,Sanak M,Cornejo-García JA

更新日期：2019-06-01 00:00:00

abstract：:Histamine is the primary mediator involved the pathophysiology of allergic rhinitis and chronic urticaria, and this explains the prominent role that histamine H(1)-receptor antagonists have in the treatment of these disorders. However, histamine is clearly not the only mediator involved in the inflammatory cascade. Th...

journal_title：Allergy

authors： Mullol J,Bousquet J,Bachert C,Canonica WG,Gimenez-Arnau A,Kowalski ML,Martí-Guadaño E,Maurer M,Picado C,Scadding G,Van Cauwenberge P

更新日期：2008-04-01 00:00:00

abstract：:Olea europaea (olive) pollen extract was prepared by aqueous extraction and characterized by biochemical and immunochemical methods. Two components, displaying respective mol. wt. of 17,000 and 19,000, were the most reactive allergens, being the doublet (designated Ole e I) recognized by most sera tested. The 19,000 m...

journal_title：Allergy

authors： De Cesare F,Pini C,Di Felice G,Caiaffa MF,Macchia L,Tursi A,Tinghino R,Palumbo S,Sallusto F,Federico R

更新日期：1993-05-01 00:00:00

abstract：:We examined the effects of glucocorticosteroids (GCS) on antigen-induced bronchial anaphylactic reactions (BAR) in SD rats immunized with ovalbumin (OA) and alum. The animals were treated with vehicle, budesonide (BUD), dexamethasone (DEX), or hydrocortisone (HC) at various times before intravenous (i.v.) antigen chal...

journal_title：Allergy

authors： Dahlbäck M,Bergstrand H,Brattsand R

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:IgE is the central antibody isotype in TH2-biased immunity and allergic diseases. The structure of intact IgE and the impact of IgE-targeting molecules on IgE however remain elusive. In order to obtain insights into IgE biology and the clinical impact, we aimed for structure determination of IgE and the comp...

journal_title：Allergy

authors： Jensen RK,Jabs F,Miehe M,Mølgaard B,Pfützner W,Möbs C,Spillner E,Andersen GR

更新日期：2020-08-01 00:00:00

abstract：:A total of 139 workers (71% of the available work force) in four grain elevator stores in Aalborg, Denmark, participated in a cross-sectional study on the prevalence of storage mite allergy among grain elevator workers. All underwent interview, prick test with a standard panel of allergens and the storage mites Acarus...

journal_title：Allergy

authors： Revsbech P,Andersen G

更新日期：1987-08-01 00:00:00

abstract：:The levels of peripheral-blood, naturally occurring aliphatic polyamines, such as putrescine, spermidine, and spermine, from 21 bronchial asthmatic patients (11 atopics and 10 nonatopics) were measured by postcolumn derivatization high-performance liquid chromatography analysis. None of the patients, except the 44-yea...

journal_title：Allergy

authors： Kurosawa M,Shimizu Y,Tsukagoshi H,Ueki M

更新日期：1992-12-01 00:00:00

abstract：:The estimation of exposure to molds and their products in the indoor environment, which may lead to the occurrence of allergies or respiratory complaints, by means of enumeration of viable parts is inadequate. Therefore, other methods must be developed. When grown under various circumstances (22 degrees C and 30 degre...

journal_title：Allergy

authors： Wijnands LM,Deisz WD,van Leusden FM

更新日期：2000-09-01 00:00:00

abstract：:708 unselected adolescents 15-17 years old were studied. They were physically examined, interviewed and skin prick tested with 12 common allergens. Questionnaires were distributed to the adolescents and their parents to investigate past and present symptoms and environmental influences. Emphasis was on the first year ...

journal_title：Allergy

authors： Suoniemi I,Björkstén F,Haahtela T

更新日期：1981-05-01 00:00:00

abstract：:Quantiative immunoelectrophoresis used for the analysis of a dialysed, centrifuged and freeze-dried extract from cow hair and dander revealed 17 antigens. Five of these were identified as serum proteins. Partial identity to antigens of serum and extract from hair and dander of goat, sheep, swine, horse, dog, cat and g...

journal_title：Allergy

authors： Prahl P,Weeke B,Løwenstein H

更新日期：1978-10-01 00:00:00

abstract：:The connective tissue disorders (also called collagen vascular diseases) represent an heterogeneous group of immunologically mediated inflammatory disorders with a large variety of affected organs besides the lungs. The respiratory system may be involved in all its components: airways, vessels, parenchyma, pleura, res...

journal_title：Allergy

authors： Crestani B

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Nuclear factor kappaB (NF-kappaB) overactivation plays a crucial role in T-helper 2 (Th2)-biased allergic airway inflammation by increased activation and decreased apoptosis of CD4(+) T cells. We have shown that targeted NF-kappaB suppression in dendritic cells by adenoviral gene transfer of a novel mutated ...

journal_title：Allergy

authors： Zhou LF,Zhang MS,Hu AH,Zhu Z,Yin KS

更新日期：2008-05-01 00:00:00

abstract：:Although studies of families, inbred populations and twins have established that asthma has a hereditary basis, little evidence has shown that intrinsic asthma has an increased familial occurrence. To document this issue, we compared the prevalence of asthma in families of intrinsic asthmatics, extrinsic asthmatics an...

journal_title：Allergy

authors： Pirson F,Charpin D,Sansonetti M,Lanteaume A,Kulling G,Charpin J,Vervloet D

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Health-related quality of Life in patients with chronic urticaria is evaluated by mean of generic instruments or questionnaire designed for skin diseases. No disease-specific tool is now available for the assessment of chronic urticaria impact from patients' viewpoint. OBJECTIVE:The aim of our study is to d...

journal_title：Allergy

authors： Baiardini I,Pasquali M,Braido F,Fumagalli F,Guerra L,Compalati E,Braga M,Lombardi C,Fassio O,Canonica GW

更新日期：2005-08-01 00:00:00

abstract：:Quantitative risk assessment (QRA) for food allergens has made considerable progress in recent years, yet acceptability of its outcomes remains stymied because of the limited extent to which it has been possible to incorporate severity as a variable. Reaction severity, particularly following accidental exposure, depen...

journal_title：Allergy

authors： Dubois AEJ,Turner PJ,Hourihane J,Ballmer-Weber B,Beyer K,Chan CH,Gowland MH,O'Hagan S,Regent L,Remington B,Schnadt S,Stroheker T,Crevel RWR

更新日期：2018-07-01 00:00:00

abstract：:We studied the effect of tea polyphenols on histamine release from rat basophilic leukemia (RBL-2H3) cells. Among tea polyphenols, (-)- epigallocatechin gallate (EGCG) most strongly and dose-dependently inhibited histamine release from cells stimulated with a calcium ionophore, A23187. (-)-Epigallocatechin (EGC) and (...

journal_title：Allergy

authors： Matsuo N,Yamada K,Shoji K,Mori M,Sugano M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Mannitol-induced bronchoconstriction in subjects with exercise-induced asthma is associated with increased urinary excretion of 9alpha, 11beta-PGF(2), a metabolite of prostaglandin D(2) (PGD(2)) serving as a mast cell marker. It has however been questioned whether or not human mast cells release PGD(2) and l...

journal_title：Allergy

authors： Gulliksson M,Palmberg L,Nilsson G,Ahlstedt S,Kumlin M

更新日期：2006-12-01 00:00:00

abstract：:A family of widely expressed ORM-like (ORMDL) proteins has been recently linked to asthma in genomewide association studies in humans and extensively explored in in vivo studies in mice. ORMDL proteins are key regulators of serine palmitoyltransferase, an enzyme catalyzing the initial step of sphingolipid biosynthesis...

journal_title：Allergy

authors： Paulenda T,Draber P

更新日期：2016-07-01 00:00:00

abstract：:Intramuscular adrenaline is the gold standard treatment for anaphylaxis. Intramuscular injection provides more rapid and higher plasma concentrations than subcutaneous routes. Given the increasing epidemic of obesity patients are at increased risk of subcutaneous delivery, we therefore assessed the depth of subcutaneo...

journal_title：Allergy

authors： Johnstone J,Hobbins S,Parekh D,O'Hickey S

更新日期：2015-06-01 00:00:00

abstract：:Asthma induced by cereal flour is a long recognized entity. We present studies of three patients affected by asthma related to exposure to cereal flour contained in animal formula feeds. Skin prick test performed with the formula feed components showed positive reactions to cereal flours (wheat, rye and barley) and ne...

journal_title：Allergy

authors： Valdivieso R,Pola J,Zapata C,Puyana J,Cuesta J,Martin C,Losada E

更新日期：1988-08-01 00:00:00

abstract：:The nasal mucociliary clearance is an important defense mechanism of the upper respiratory tract. It is known to be influenced by many pharmacologic substances. We investigated the effects of three topical intranasal antiallergic formulations containing disodium cromoglycate (DNCG), dimethindene maleate (DMM), and aze...

journal_title：Allergy

authors： Alberty J,Stoll W

更新日期：1998-10-01 00:00:00