Usefulness of monocyte to HDL-cholesterol ratio to predict high SYNTAX score in patients with stable coronary artery disease.

Abstract:

AIM:We aimed to investigate whether baseline monocyte to high-density lipoprotein cholesterol ratio (MHR), an easily available inflammatory and oxidative stress marker, is associated with SYNTAX score. PATIENTS & METHODS:In this cross-sectional study, n = 1229 consecutive patients with coronary artery disease were classified into two groups, low SYNTAX score (≤22) and high SYNTAX score (≥23). RESULTS:MHRs were significantly higher in patients with high SYNTAX score (p < 0.05). In multivariate regression analysis, MHR remained as independent predictor of high SYNTAX score together with C-reactive protein (CRP), hypertension and diabetes mellitus. In correlation analysis, MHR showed significant positive correlations with SYNTAX score (r = 0.371, p < 0.001) and CRP level (r = 0.336, p < 0.001). CONCLUSION:This study suggests MHR is independently associated with burden of coronary atherosclerosis.

journal_name

Biomark Med

journal_title

Biomarkers in medicine

authors

Akboga MK,Balci KG,Maden O,Ertem AG,Kirbas O,Yayla C,Acar B,Aras D,Kisacik H,Aydogdu S

doi

10.2217/bmm-2015-0050

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

375-83

issue

4

eissn

1752-0363

issn

1752-0371

journal_volume

10

pub_type

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