A contemporary review of paediatric heart transplantation and mechanical circulatory support.

Abstract:

:Improvements in the care of children with cardiomyopathy, CHDs, and acquired heart disease have led to an increased number of children surviving with advanced heart failure. In addition, the advent of more durable mechanical circulatory support options in children has changed the outcome for many patients who otherwise would have succumbed while waiting for heart transplantation. As a result, more children with end-stage heart failure are being referred for heart transplantation, and there is increased demand for a limited donor organ supply. A review of important publications in the recent years related to paediatric heart failure, transplantation, and mechanical circulatory support show a trend towards pushing the limits of the current therapies to address the needs of this growing population. There have been a number of publications focussing on previously published risk factors perceived as barriers to successful heart transplantation, including elevated pulmonary vascular resistance, medication non-adherence, re-transplantation, transplantation of the failed Fontan patient, and transplantation in an infant or child bridged with mechanical circulatory support. This review will highlight some of these key articles from the last 3 years and describe recent advances in the understanding, diagnosis, and management of children with end-stage heart disease.

journal_name

Cardiol Young

journal_title

Cardiology in the young

authors

Kindel SJ,Everitt MD

doi

10.1017/S1047951116000184

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

851-9

issue

5

eissn

1047-9511

issn

1467-1107

pii

S1047951116000184

journal_volume

26

pub_type

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