[Correlates of Cognitive Impairment of Rheumatic Disease: Systematic Review and Meta-analysis].

Abstract:

PURPOSE:This study was conducted to synthesis the results of research on relationships of cognitive impairment with multi-dimensional correlates of rheumatic disease through a systematic literature review and meta-analysis. METHODS:For the study purpose, 23 studies were selected through a systematic process of searching the literature. RESULTS:The study results showed that among general characteristics, age and education were the variables having a significant relationship with cognitive impairment. Among health risk factors, obesity appeared to have a significant positive relationship with cognitive impairment. For past history, diabetes and hypertension were shown to have a significant positive relationship with cognitive impairment. It was noted also that aPL, one of the physiological factor, had significant association with cognitive impairment. None of the medication related factors had a significant relationship with cognitive impairment. Results showed that among disease related factors, disease activity had the highest relationship with cognitive impairment. Depression, among psychological factors, was the only variable having a significant relationship with cognitive impairment. CONCLUSION:The findings indicate that the variables strongly impacting on cognitive impairment in rheumatic disease are depression and disease activity.

journal_name

J Korean Acad Nurs

authors

Mo J,Park J,Oh H

doi

10.4040/jkan.2016.46.1.1

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

1-18

issue

1

eissn

2005-3673

issn

2093-758X

pii

46.1

journal_volume

46

pub_type

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