Minimal Residual Disease and Childhood Leukemia: Standard of Care Recommendations From the Pediatric Oncology Group of Ontario MRD Working Group.

Abstract:

:Minimal residual disease (MRD) is an independent predictor of relapse risk in children with leukemia and is widely used for risk-adapted treatment. This article summarizes current evidence supporting the use of MRD, including clinical significance, current international clinical practice, impact statement, and recommended indications. The proposed MRD recommendations have been endorsed by the MRD Working Group of the Pediatric Oncology Group of Ontario and provide the foundation for a strategy that aims at equitable access to MRD evaluation for children with leukemia.

journal_name

Pediatr Blood Cancer

journal_title

Pediatric blood & cancer

authors

Athale UH,Gibson PJ,Bradley NM,Malkin DM,Hitzler J,POGO MRD Working Group.

doi

10.1002/pbc.25939

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

973-82

issue

6

eissn

1545-5009

issn

1545-5017

journal_volume

63

pub_type

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