Abstract:
:Dizziness and vertigo frequently occur after cochlear implantation (CI) surgery, particularly during the early stages. It could recover over time but some of the patients suffered from delayed or sustained vestibular symptoms after CI. This study used rat animal models to investigate the effect of unilateral cochleostomy on the vestibular organs over time. Twenty-seven Sprague Dawley rats underwent cochleostomy to evaluate the postoperative changes in hearing threshold, gain and symmetry of the vestibular ocular response, overall balance function, number of hair cells in the crista, and the c-Fos activity in the brainstem vestibular nucleus. Loss of vestibular function was observed during the early stages, but function recovered partially over time. Histopathological findings demonstrated a mild decrease in vestibular hair cells numbers. Increased c-Fos immunoreactivity in the vestibular nucleus, observed in the early stages after cochleostomy, decreased over time. Cochleostomy is a risk factor for peripheral vestibular organ damage that can cause functional impairment in the peripheral vestibular organs. Altered vestibular nucleus activity may be associated with vestibular compensation and plasticity after unilateral cochleostomy.
journal_name
Neural Plastjournal_title
Neural plasticityauthors
Suh MW,Hyun J,Lyu AR,Kim DW,Park SJ,Choi JW,Hur GM,Park YHdoi
10.1155/2016/7287180subject
Has Abstractpub_date
2016-01-01 00:00:00pages
7287180eissn
2090-5904issn
1687-5443journal_volume
2016pub_type
杂志文章abstract::Functional and morphological studies in children affected by Attention Deficit Hyperactivity Disorder (ADHD) suggest a prefrontal cortex (PFc) dysfunction. This cortical region is regulated by subcortical systems including noradrenergic (NEergic), dopaminergic (DAergic), cholinergic, serotonergic, and histaminergic pa...
journal_title:Neural plasticity
pub_type: 杂志文章,评审
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journal_title:Neural plasticity
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2019/2490750
更新日期:2019-06-26 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2018/7301530
更新日期:2018-12-02 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2017/7543686
更新日期:2017-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2020/8851525
更新日期:2020-09-22 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1155/2018/4897276
更新日期:2018-05-27 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2018/4135708
更新日期:2018-10-10 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2008/814815
更新日期:2008-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/2015/653727
更新日期:2015-01-01 00:00:00
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journal_title:Neural plasticity
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doi:10.1155/2016/8764238
更新日期:2016-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2016/1243527
更新日期:2016-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2016/9847696
更新日期:2016-01-01 00:00:00
abstract::In this study, we attempted to test whether tyrosine hydroxylase (TH), the first rate-limiting enzyme of catecholamine synthesis, is confined to the perikarya of activated magnocellular vasopressinergic (VPergic) neurons or is also present in their distal axons in the pituitary posterior lobe (PL). In addition, we eva...
journal_title:Neural plasticity
pub_type: 杂志文章
doi:10.1155/NP.2000.179
更新日期:2000-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
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更新日期:2017-01-01 00:00:00
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journal_title:Neural plasticity
pub_type: 杂志文章,评审
doi:10.1155/2017/5405104
更新日期:2017-01-01 00:00:00
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journal_title:Neural plasticity
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doi:10.1155/2018/9828725
更新日期:2018-08-06 00:00:00
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journal_title:Neural plasticity
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更新日期:2008-01-01 00:00:00