Abstract:
:The interactions of sodium balance and response of renin-angiotensin-aldosterone system are important for maintaining the hemodynamic stability in physiological conditions. However, the influence of short-term sodium intake intervention in the response of renin-angiotensin system (RAS) on hypertensive patients is still unclear. Thus, we conducted a clinical trial to investigate the effects of short-term sodium intake intervention on the response of RAS in hypertensive patients.One hundred twenty-five primary Chinese hypertensive patients were divided into high, moderate, and low sodium groups by 24-hour urinary sodium excretion (UNa). All the patients received a 10-day dietary sodium intake intervention with standardized sodium (173.91mmol/day) and potassium (61.53mmol/day). Blood pressure, urinary sodium, urinary potassium, plasma sodium, potassium, creatinine, the levels of plasma renin activity, plasma angiotensin II concentrations (AT-II), and plasma aldosterone concentrations were detected before and after the intervention.Before the intervention, no differences were found in blood pressure and RAS among 3 groups. After standardized dietary sodium intake intervention, both UNa excretion and systolic pressure decreased in high-sodium group, while they increased in moderate and low-sodium groups. Intriguingly, there were no changes in the levels of plasma renin activity, AT-II, and plasma aldosterone concentrations among 3 groups during the intervention.The present study demonstrated that the influenced sodium excretion and blood pressure by short-term sodium intake intervention were independent of RAS quick response in Chinese hypertensive patients.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Feng W,Cai Q,Yuan W,Liu Y,Bardeesi ASA,Wang J,Chen J,Huang Hdoi
10.1097/MD.0000000000002602subject
Has Abstractpub_date
2016-02-01 00:00:00pages
e2602issue
6eissn
0025-7974issn
1536-5964pii
00005792-201602090-00022journal_volume
95pub_type
临床试验,杂志文章相关文献
MEDICINE文献大全abstract::One strategy for controlling the skyrocketing costs of cancer care may be to target high-tech/high-cost imaging at the end of life (EOL). This population-based study investigated receipt of high-tech/high-cost imaging and its determinants for Taiwanese patients with metastatic cancer in their last month of life.Indivi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001354
更新日期:2015-08-01 00:00:00
abstract::There is still debate on whether high uric acid increases bone mineral density (BMD) against osteoporotic fracture or bone resorption caused by gout inflammation. This study aimed to evaluate whether gout offers a protective effect on bone health or not. We conducted a nationwide population-based retrospective cohort ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004669
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:One of the most common complications following autologous cranioplasty is bone flap resorption (BFR). Severe BFR can lead to revision surgery with implantation of synthetic bone flap and also necessarily lead to higher hospital expenses. This study aims to perform a meta-analysis to summarize available evide...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021035
更新日期:2020-07-10 00:00:00
abstract:BACKGROUND:To investigate the effect of high-volume hemofiltration (HVHF) on Th17/Treg imbalance in patients with severe acute pancreatitis (SAP). METHODS:Forty-two patients with SAP were randomly received 24 hours of continuous HVHF (n = 21) or without HVHF (n = 21). At day 28, all 42 patients were divided into survi...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000021491
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:To explore the features and function of gut microbiota in necrotizing enterocolitis patients over 28 gestational age weeks through a case-control study. METHODS:Fecal samples from patients with NEC over 28 gestational week age and matched control cases were collected. DNA of the fecal samples was extracted ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017206
更新日期:2019-10-01 00:00:00
abstract::The relevance of LP(a), Hcy, and D-D in ischemic cerebrovascular disease remains undefined. This study aimed to assess the associations of plasma LP(a), Hcy and D-D levels with the subtype of ischemic cerebrovascular disease.Patients with ischemic cerebrovascular disease admitted to the Taixing People's Hospital were ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014910
更新日期:2019-03-01 00:00:00
abstract::Osteocalcin (OC) is an endocrine hormone that regulates glucose metabolism.The aim of this study was to investigate the relationship between serum OC levels and glucose metabolism after trauma.This was a retrospective study of trauma patients admitted to the Department of Emergency Medicine between October 2017 and Ap...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021901
更新日期:2020-09-04 00:00:00
abstract:BACKGROUND:A worldwide concern has been raised that novel infectious diseases may outbreak rapidly with a limited response time due to globalization. Severe Acute Respiratory Syndrome, influenza A, Avian Influenza Virus, and Corona Virus Disease 2019 are acute respiratory diseases that have been affected by the movemen...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021249
更新日期:2020-07-24 00:00:00
abstract::Management of large tissue defects resulting from local wide resection of perianal is a clinical challenge for surgeons. The aim of the present study was to investigate the efficacy of negative pressure wound therapy (NPWT) following skin grafting on perianal surgical wound healing.Included in this study were 12 patie...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004670
更新日期:2016-08-01 00:00:00
abstract::The effect of neoadjuvant chemotherapy on the survival of patients with thoracic esophageal squamous cell carcinomas (ESCCs) remains controversial. The optimal management strategy for resectable ESCCs varies regionally based on local randomized controlled trials. A systematic review and meta-analysis was conducted to ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000001102
更新日期:2015-07-01 00:00:00
abstract::Several studies have investigated the incidence of and risk factors for acute exacerbation (AE) in patients with interstitial lung disease (ILD) after lung resection surgery. However, the incidence and risk factors for AE-ILD after non-pulmonary surgery are not known. The aim of this study was to investigate the incid...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014296
更新日期:2019-02-01 00:00:00
abstract::To characterize the current frequency of HIV-1 coreceptor usage in China and assess the candidacy of CCR5 antagonists for treatment of HIV infections. In addition, we aimed to evaluate the potential of X4/DM virus transmission in recently infected men who have sex with men (MSM) individuals.Viral tropism testing was p...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005017
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Rotavirus (RV) can cause vomiting and diarrhea in infants and children, and could be treated clinically with immunoglobulin Y (IgY), which is an immunoglobulin extracted from chicken yolk. There is no systematic evaluation of immunoglobulin in the treatment of rotavirus enteritis. Therefore, we systematicall...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000016100
更新日期:2019-07-01 00:00:00
abstract:RATIONALE:A dural arteriovenous fistula (DAVF) refers to an abnormal direct connection between an intracranial artery and a dural venous sinus. A DAVF presenting with parkinsonism is rare, and is therefore easily misdiagnosed. Therefore, early consideration of DAVF in the differential diagnosis of reversible parkinsoni...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009005
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:CyclinD1 (CCND1) is a key cell cycle regulatory protein. A large number of epidemiological studies have assessed the potential correlation between the CCND1 G870A polymorphism and the risk of colorectal cancer (CRC), but their findings have been inconsistent. To obtain a more precise understanding of the ass...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000008269
更新日期:2017-10-01 00:00:00
abstract::We prospectively identified cases of pneumococcal pneumonia and used stringent criteria to stratify them into bacteremic and nonbacteremic cases. Although patients were distributed among racial groups in proportion to all patients seen at this medical center, the proportion of African-Americans with bacteremic disease...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/00005792-200007000-00002
更新日期:2000-07-01 00:00:00
abstract:RATIONALE:Total hip arthroplasty (THA) concomitant with subtrochanteric femoral shortening osteotomy for Crowe type IV dysplastic hip has been reported. However, the combination of subtrochanteric femoral osteotomy and revision THA has only been mentioned in one case report. PATIENT CONCERNS:A 67-year-old female had a...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012934
更新日期:2018-10-01 00:00:00
abstract::Mastocytosis is a heterogeneous group of diseases with a young median age at diagnosis. Usually indolent and self-limited in childhood, the disease can exhibit aggressive progression in mid-adulthood. Our objectives were to describe the characteristics of the disease when diagnosed among elderly patients, for which ra...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000003901
更新日期:2016-06-01 00:00:00
abstract::Inhalation anesthetics provide myocardial protection for cardiac surgery. This study was undertaken to compare the perioperative effects between isoflurane and fentanyl-midazolam-based anesthesia for heart transplantation. A retrospective cohort study was conducted by reviewing the medical records of heart transplanta...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004699
更新日期:2016-08-01 00:00:00
abstract::Assessment the prevalence of hypertension and its relation to selected indicators of health status and performance, including classification of BMI, obesity classifications, and body structure in a large test group of 19-year-old men.The study was observational-retrospective, and included a group of 17,282 men, aged 1...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020398
更新日期:2020-05-29 00:00:00
abstract::African Americans (AA) with systemic sclerosis (SSc) have a worse prognosis compared to Americans of European descent (EA). We conducted the current study to test the hypothesis that AA patients with SSc have more severe disease and poorer outcomes compared to EA patients when afflicted with pulmonary arterial hyperte...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000032
更新日期:2014-07-01 00:00:00
abstract::Congenital chloride losing diarrhea (CCLD) is a rare type of chronic watery diarrhea due to mutations in SLC26A3 gene leading to defective chloride-bicarbonate exchanges with the resultant loss of chloride and retention of bicarbonate.We aim to define pediatric Saudi CCLD patients' characteristics to achieve prompt di...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015928
更新日期:2019-05-01 00:00:00
abstract::This study used Taiwan's National Health Insurance medical claims to investigate the predictors for operative modes chosen by early-stage breast cancer patients; as well as to assess whether operative modes are associated with risk of mood disorder. We included 36,377 patients with breast cancer who received surgery b...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002510
更新日期:2016-01-01 00:00:00
abstract::The main objective of the study was to evaluate the efficacy and safety of dabrafenib alone or combined with trametinib for compassionate use in patients with metastatic melanoma.This retrospective, observational study involved 135 patients with unresectable stage IIIC or stage IV melanoma from an expanded-access prog...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009523
更新日期:2017-12-01 00:00:00
abstract::Acute cellular rejection after liver transplantation (LT) can be treated with steroid pulse therapy, but there is no ideal treatment for steroid-resistant acute rejection (SRAR). We aimed to determine the feasibility and potential complications of rabbit anti-thymocyte globulin (rATG) application to treat SRAR in live...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003711
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Residual postoperative neuromuscular blockade is an important clinical issue. Neuromuscular monitoring is usually used to evaluate neuromuscular recovery in patients undergoing general anesthesia. However, this procedure is inconvenient and not widely adopted. We aimed to examine the correlation between grip...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000013940
更新日期:2019-01-01 00:00:00
abstract::Cirrhosis and idiopathic portal hypertension (IPH) are 2 major diseases showing portal hypertension. However, characteristics and outcomes of IPH with ascites have not yet been determined. The aim of the study was to examine the influence of ascites on the long-term clinical course of IPH.This observational study comp...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001056
更新日期:2015-07-01 00:00:00
abstract::The aim of this study was to explore the impact of 3% hypertonic saline (HS) intragastric administration for patients who underwent upper gastrointestinal surgery.During the postoperative period, 3% HS has been suggested as a means to improve the intestinal edema and reduce gastrointestinal complications.The medical r...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006121
更新日期:2017-03-01 00:00:00
abstract:AIMS:Nicorandil, which is a mitochondrial ATP-sensitive potassium channel opener, is believed to improve perioperative myocardial injury (PMI) in patients undergoing percutaneous coronary intervention (PCI), but recent studies have shown that nicorandil treatment did not improve functional and clinical outcomes in pati...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000014165
更新日期:2019-01-01 00:00:00
abstract:RATIONALE:Iatrogenic chylous leakage (CL) is a rare but potentially life-threatening complication after neck surgery. In cirrhotic patient, the massive CL is even more intractable and extremely dangerous due to portal hypertension. PATIENTS CONCERNS:A 54-year-old liver cirrhotic patient had milky fluid leakage from le...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009103
更新日期:2017-12-01 00:00:00