Slip knots and unfastening topologies enhance toughness without reducing strength of silk fibroin fibres.

abstract：:Organisms modify and choose components of their local environments. This 'niche construction' can alter ecological processes, modify natural selection and contribute to inheritance through ecological legacies. Here, we propose that niche construction initiates and modifies the selection directly affecting the construc...

journal_title：Interface focus

authors： Laland K,Odling-Smee J,Endler J

更新日期：2017-10-06 00:00:00

abstract：:Clinicians face many challenges when diagnosing and treating breast cancer. These challenges include interpreting and co-locating information between different medical imaging modalities that are used to identify tumours and predicting where these tumours move to during different treatment procedures. We have develope...

journal_title：Interface focus

authors： Babarenda Gamage TP,Malcolm DTK,Maso Talou G,Mîra A,Doyle A,Nielsen PMF,Nash MP

更新日期：2019-08-06 00:00:00

abstract：:Silica carriers equipped with molecular and supramolecular pH-sensitive nanovalves were designed by combination of sol-gel synthesis and selective postsynthetic modification. Mesoporous structure of synthesized materials was characterized by low-temperature nitrogen adsorption-desorption, small-angle X-ray diffraction...

journal_title：Interface focus

authors： Roik NV,Belyakova LA

更新日期：2016-12-06 00:00:00

abstract：:Noble metal nanoparticles (NPs) show distinctive plasmonic optical properties and superior photostability, enabling them to serve as photostable multi-coloured optical molecular probes and sensors for real-time in vivo imaging. To effectively study biological functions in vivo, it is essential that the NP probes are b...

journal_title：Interface focus

authors： Browning LM,Huang T,Xu XH

更新日期：2013-06-06 00:00:00

abstract：:Periodontitis is a polymicrobial, biofilm-caused, inflammatory disease affecting the tooth-supporting tissues. It is not only the leading cause of tooth loss worldwide, but can also impact systemic health. The development of effective treatment strategies is hampered by the complicated disease pathogenesis which is be...

journal_title：Interface focus

authors： Bloch S,Tomek MB,Friedrich V,Messner P,Schäffer C

更新日期：2019-04-06 00:00:00

abstract：:Biofuels production from microalgae attracts much attention but remains an unproven technology. We explore routes to enhance production through modifications to a range of generic microalgal physiological characteristics. Our analysis shows that biofuels production may be enhanced ca fivefold through genetic modificat...

journal_title：Interface focus

authors： Flynn KJ,Mitra A,Greenwell HC,Sui J

更新日期：2013-02-06 00:00:00

abstract：:A tumour is a heterogeneous population of cells that competes for limited resources. In the clinic, we typically probe the tumour by biopsy, and then characterize it by the dominant genetic clone. But genotypes are only the first link in the chain of hierarchical events that leads to a specific cell phenotype. The rel...

journal_title：Interface focus

authors： Gallaher J,Anderson AR

更新日期：2013-08-06 00:00:00

abstract：:The development of bioadhesives inspired from marine animals is a promising approach to generate new tissue-compatible medical components. A number of marine species, through their adhesive properties, also represent significant foulers that become increasingly problematic to aquaculture, shipping or local biodiversit...

journal_title：Interface focus

authors： Pennati R,Rothbächer U

更新日期：2015-02-06 00:00:00

abstract：:Multiscale simulations are essential in the biomedical domain to accurately model human physiology. We present a modular approach for designing, constructing and executing multiscale simulations on a wide range of resources, from laptops to petascale supercomputers, including combinations of these. Our work features t...

journal_title：Interface focus

authors： Groen D,Borgdorff J,Bona-Casas C,Hetherington J,Nash RW,Zasada SJ,Saverchenko I,Mamonski M,Kurowski K,Bernabeu MO,Hoekstra AG,Coveney PV

更新日期：2013-04-06 00:00:00

abstract：:Recent advances in design, sensing and control have led to aerial robots that offer great promise in a range of real-world applications. However, one critical open question centres on how to improve the energetic efficiency of aerial robots so that they can be useful in practical situations. This review paper provides...

journal_title：Interface focus

authors： Karydis K,Kumar V

更新日期：2017-02-06 00:00:00

abstract：:In recent years, there has been a move away from the use of static in vitro two-dimensional cell culture models for testing the chemical safety and efficacy of drugs. Such models are increasingly being replaced by more physiologically relevant cell culture systems featuring dynamic flow and/or three-dimensional struct...

journal_title：Interface focus

authors： Hyndman L,McKee S,Mottram NJ,Singh B,Webb SD,McGinty S

更新日期：2020-04-06 00:00:00

abstract：:The emergence of life on Earth (and elsewhere) must have occurred in a milieu that is far from equilibrium, such as at alkaline hydrothermal vents that would have harboured built-in gradients in temperature, redox potential and pH along with precipitated iron-bearing minerals capable of separating these gradients, con...

journal_title：Interface focus

authors： Ponce A

更新日期：2019-12-06 00:00:00

abstract：:The Dual-Wavelength Echidna Lidar (DWEL), a full waveform terrestrial laser scanner (TLS), has been used to scan a variety of forested and agricultural environments. From these scanning campaigns, we summarize the benefits and challenges given by DWEL's novel coaxial dual-wavelength scanning technology, particularly f...

journal_title：Interface focus

authors： Li Z,Schaefer M,Strahler A,Schaaf C,Jupp D

更新日期：2018-04-06 00:00:00

abstract：:Dynamic remodelling of actin stress fibres (SFs) allows non-muscle cells to adapt to applied forces such as uniaxial cell shortening. However, the mechanism underlying rapid and selective disassembly of SFs oriented in the direction of shortening remains to be elucidated. Here, we investigated how myosin crossbridge c...

journal_title：Interface focus

authors： Matsui TS,Kaunas R,Kanzaki M,Sato M,Deguchi S

更新日期：2011-10-06 00:00:00

abstract：:Nanoparticles do not exist in thermodynamical equilibrium because of high surface free energy, thus they have only kinetic stability. Spontaneous changes can be delayed by designed surface coating. In biomedical applications, superparamagnetic iron oxide nanoparticles (SPIONs) require an optimized coating in order to ...

journal_title：Interface focus

authors： Tombácz E,Farkas K,Földesi I,Szekeres M,Illés E,Tóth IY,Nesztor D,Szabó T

更新日期：2016-12-06 00:00:00

abstract：:Apart from interacting, prey and predators may also avoid each other by moving into refuges where they lack food, yet survive by switching to an energy-saving physiological state. Lotka-Volterra models of predator-prey interactions ignore this option. Therefore, we have modelled this game of 'joining versus opting out...

journal_title：Interface focus

authors： Staňková K,Abate A,Sabelis MW,Buša J,You L

更新日期：2013-12-06 00:00:00

abstract：:Pentameric ligand-gated ion channels (pLGICs) are an important class of widely expressed membrane neuroreceptors, which play a crucial role in fast synaptic communications and are involved in several neurological conditions. They are activated by the binding of neurotransmitters, which trigger the transmission of an e...

journal_title：Interface focus

authors： Crnjar A,Comitani F,Melis C,Molteni C

更新日期：2019-06-06 00:00:00

abstract：:A numerical model for orthogonal cutting using the material point method was applied to woodcutting using a bench plane. The cutting process was modelled by accounting for surface energy associated with wood fracture toughness for crack growth parallel to the grain. By using damping to deal with dynamic crack propagat...

journal_title：Interface focus

authors： Nairn JA

更新日期：2016-06-06 00:00:00

abstract：:Cell migration participates in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. The cells specifically migrate to destiny sites induced by the gradually varying conce...

journal_title：Interface focus

authors： Wu J,Mao Z,Tan H,Han L,Ren T,Gao C

更新日期：2012-06-06 00:00:00

abstract：:Moving from homogeneous water-splitting photocatalytic systems to photoelectrochemical devices requires the preparation and evaluation of novel p-type transparent conductive photoelectrode substrates. We report here on the sensitization of polystyrene-block-poly-(2-vinylpyridine) (PS-b-P2VP) diblock copolymer-template...

journal_title：Interface focus

authors： Massin J,Bräutigam M,Kaeffer N,Queyriaux N,Field MJ,Schacher FH,Popp J,Chavarot-Kerlidou M,Dietzek B,Artero V

更新日期：2015-06-06 00:00:00

abstract：:The paper reviews two computing models by DNA self-assembly whose proof of principal have recently been experimentally confirmed. The first model incorporates DNA nano-devices and triple crossover DNA molecules to algorithmically arrange non-DNA species. This is achieved by simulating a finite-state automaton with out...

journal_title：Interface focus

authors： Jonoska N,Seeman NC

更新日期：2012-08-06 00:00:00

abstract：:Pancreatic β-cells use Ca(2+)-dependent exocytosis of large dense core vesicles to release insulin. Exocytosis in β-cells has been studied biochemically, biophysically and optically. We have previously developed a biophysical method to monitor release of endogenous intragranular constituents that are co-released with ...

journal_title：Interface focus

authors： Galvanovskis J,Braun M,Rorsman P

更新日期：2011-02-06 00:00:00

abstract：:The placenta provides all the nutrients required for the fetus through pregnancy. It develops dynamically, and, to avoid rejection of the fetus, there is no mixing of fetal and maternal blood; rather, the branched placental villi 'bathe' in blood supplied from the uterine arteries. Within the villi, the feto-placental...

journal_title：Interface focus

authors： Clark AR,Lin M,Tawhai M,Saghian R,James JL

更新日期：2015-04-06 00:00:00

abstract：:In this paper, we show that solutions to ordinary differential equations describing the large-population limits of Markovian stochastic epidemic models can be interpreted as survival or cumulative hazard functions when analysing data on individuals sampled from the population. We refer to the individual-level survival...

journal_title：Interface focus

authors： KhudaBukhsh WR,Choi B,Kenah E,Rempała GA

更新日期：2020-02-06 00:00:00

abstract：:Most ecological interactions occur in environments that are spatially and temporally heterogeneous-'patchy'-across a wide range of scales. In contrast, most theoretical models of ecological interactions, especially large-scale models applied to societal issues such as climate change, resource management and human heal...

journal_title：Interface focus

authors： Grünbaum D

更新日期：2012-04-06 00:00:00

abstract：:Eukaryogenesis-the process by which the eukaryotic cell emerged-has long puzzled scientists. It has been assumed that the fossil record has little to say about this process, in part because important characters such as the nucleus and mitochondria are rarely preserved, and in part because the prevailing model of early...

journal_title：Interface focus

authors： Porter SM

更新日期：2020-08-06 00:00:00

abstract：:'Managed grazing' is gaining attention for its potential to contribute to climate change mitigation by reducing bare ground and promoting perennialization, thereby enhancing soil carbon sequestration (SCS). Understanding why ranchers adopt managed grazing is key to developing the right incentives. In this paper, we ex...

journal_title：Interface focus

authors： Gosnell H,Charnley S,Stanley P

更新日期：2020-10-06 00:00:00

abstract：:[This corrects the article DOI: 10.1098/rsfs.2017.0015.]. ...

journal_title：Interface focus

authors： Müller GB

更新日期：2017-12-06 00:00:00

abstract：:Material deformation and pitting from cavitation bubble collapse is investigated using fluid and material dynamics and their interaction. In the fluid, a novel hybrid approach, which links a boundary element method and a compressible finite difference method, is used to capture non-spherical bubble dynamics and result...

journal_title：Interface focus

authors： Chahine GL,Hsiao CT

更新日期：2015-10-06 00:00:00

abstract：:This article uses an integrative systems biological view of the relationship between genotypes and phenotypes to clarify some conceptual problems in biological debates about causality. The differential (gene-centric) view is incomplete in a sense analogous to using differentiation without integration in mathematics. D...

journal_title：Interface focus

authors： Noble D

更新日期：2011-02-06 00:00:00