Abstract:
:Insulin-induced changes in protein kinase C were examined in cytosol and membrane fractions of rat adipocytes enzymatically after Mono Q column chromatography and by immunoblotting. During a 5-20 min period of insulin treatment, cytosolic protein kinase C decrease by approximately 50%, whereas membrane protein kinase C increased nearly 2-fold. These findings suggest that insulin stimulates the translocation of protein kinase C in rat adipocytes.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Ishizuka T,Cooper DR,Farese RVdoi
10.1016/0014-5793(89)81565-0subject
Has Abstractpub_date
1989-11-06 00:00:00pages
337-40issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(89)81565-0journal_volume
257pub_type
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