Abstract:
:Intracellular Ca(2+) signals are essential for stem cell differentiation due to their ability to control signaling pathways involved in this process. Arginine vasopression (AVP) is a neurohypophyseal hormone that increases intracellular Ca(2+) concentration during adipogenesis via V1a receptors, Gq-proteins and the PLC-IP3 pathway in human adipose-derived stromal/stem cells (hASCs). These Ca(2+) signals originate through calcium release from pools within the endoplasmic reticulum and the extracellular space. AVP supplementation to the adipogenic media inhibits adipogenesis and key adipocyte marker genes. This review focuses on the intersection between AVP, Ca(2+) signals and ASC differentiation.
journal_name
Cell Calciumjournal_title
Cell calciumauthors
Tran TD,Gimble JM,Cheng Hdoi
10.1016/j.ceca.2015.12.006subject
Has Abstractpub_date
2016-03-01 00:00:00pages
135-9issue
2-3eissn
0143-4160issn
1532-1991pii
S0143-4160(16)00002-6journal_volume
59pub_type
杂志文章,评审相关文献
CELL CALCIUM文献大全abstract::The Ca2+-sensitive dye quin-2 was used to measure the cytosolic free Ca2+ (Cai2+) in suspensions of ventricular myocytes isolated from cat and rat ventricles. Following an isolation procedure that was similar for both species, the cells were loaded with quin-2 AM (25 microM) for 30 min at 37 degrees C. After two washe...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(87)90002-9
更新日期:1987-08-01 00:00:00
abstract::In previous studies we have characterised various properties of capacitative Ca2+ entry (CCE) in different epithelia. After Ca2+ store depletion with PLC/InsP3-coupled agonists or by inhibition of store Ca2+ uptake, with for example thapsigargin, Ca2+ influx is activated. This leads to a sustained cellular response (e...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/s0143-4160(97)90112-3
更新日期:1997-08-01 00:00:00
abstract::CatSper is a sperm-specific Ca(2+) channel that plays an essential role in the male fertility. However, its biophysical properties have been poorly characterized mainly due to its deficient heterologous expression. As other voltage-gated Ca(2+) channels (CaVs), CatSper possesses a conserved Ca(2+)-selective filter mot...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2016.03.011
更新日期:2016-07-01 00:00:00
abstract::The release of Ca2+ ions from the sarcoplasmic reticulum through ryanodine receptor calcium release channels represents the critical step linking electrical excitation to muscular contraction in the heart and skeletal muscle (excitation-contraction coupling). Two small Ca2+ binding proteins, S100A1 and calmodulin, hav...
journal_title:Cell calcium
pub_type: 杂志文章,评审
doi:10.1016/j.ceca.2011.06.001
更新日期:2011-10-01 00:00:00
abstract::Pituitary neuropeptide oxytocin is increasingly recognised as a cardiovascular hormone, in addition to its many regulatory roles in other organ systems. Studies in atrial and ventricular myocytes from the neonatal and adult rats have identified synthesis of oxytocin and the expression of oxytocin receptors in these ce...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2019.102099
更新日期:2019-12-01 00:00:00
abstract::Within the CNS, distinct neurons may rely on different processes to modulate cytosolic Ca2+ depending on the network developmental phase. In particular, in the immature spinal cord, synchronous electrical discharges are coupled with biochemical signals triggered by intracellular Ca2+ waves. Nevertheless, the presence ...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2006.07.006
更新日期:2007-04-01 00:00:00
abstract::The regulation of intracellular Ca(2+) signalling by phosphorylation processes remains poorly defined, particularly with regards to tyrosine phosphorylation. Evidence from non-excitable cells implicates tyrosine phosphorylation in the activation of so-called store-operated Ca(2+) channels (SOCCs), but their involvemen...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2009.04.001
更新日期:2009-07-01 00:00:00
abstract::Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent Ca2+ mobilizing second messenger which triggers Ca2+ release in both sea urchin egg homogenates and in mammalian cells. The NAADP binding protein has not been identified and the regulation of NAADP mediated Ca2+ release remains controversial. To address...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2019.102060
更新日期:2019-11-01 00:00:00
abstract::Glucose induces large amplitude oscillations of the cytoplasmic Ca2+ concentration ([Ca2+]i) in pancreatic beta-cells. The effects of temperature on these oscillations were examined by monitoring [Ca2+]i continuously in single beta-cells from ob/ob-mice using dual wavelength microfluorometry. The oscillations of [Ca2+...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(90)90053-w
更新日期:1990-06-01 00:00:00
abstract::It has been reported that leukotriene B4 can translocate calcium across model membranes (Serhan et. al., (1982) J. Biol. Chem., 257: 4746). Such ionophoretic behavior could account for its biological effects. We have examined the effect of chromatographically pure leukotriene B4 on Ca2+ permeability when added exogeno...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(87)90028-5
更新日期:1987-12-01 00:00:00
abstract::An inward current responsible for hormone regulated Ca2+ entry has been identified in cultured rat hepatocytes using whole cell patch clamp. Addition of 20 nM vasopressin or of 100 microM ATP induced the inward current, which could be observed more clearly after blocking an outward K+ current. This large outward K+ cu...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(95)90042-x
更新日期:1995-07-01 00:00:00
abstract::The L-type Ca2+ channel (Ca(v)1.2) is the main pathway for trans-sarcolemmal (SL) Ca2+ influx in cardiac myocytes. To maintain Ca2+ homeostasis, chronic SL Ca(2+)-influx must be matched by chronic SL efflux. In this study we tested the hypothesis that chronic downregulation of SL Ca2+ entry regulates SL extrusion. We ...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2008.01.004
更新日期:2008-10-01 00:00:00
abstract::The formation of a heterotetrameric complex between annexin 2 (anx 2) and S100A10 plays an important role in regulating the cellular distribution and biochemical properties of anx 2. A major distinction between the anx 2-S100A10 complex and other annexin-S100 complexes is that S100A10 binding to anx 2 occurs independe...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2007.11.001
更新日期:2008-08-01 00:00:00
abstract::Transient receptor potential cation channel, subtype melastatin 2 (TRPM2), is important for several physiological functions, such as immune response or temperature regulation. Recently, the structure of full-length TRPM2 from zebrafish was published (Huang et al., 2018) proposing a new activation mechanism - is it rea...
journal_title:Cell calcium
pub_type: 评论,杂志文章
doi:10.1016/j.ceca.2018.11.001
更新日期:2018-12-01 00:00:00
abstract::The type 1 inositol 1,4,5-trisphosphate receptor (IP3R1) mediates increases in the intracellular concentration of Ca(2+) ([Ca(2+)]i) during fertilization in mammalian eggs. The activity of IP3R1 is enhanced during oocyte maturation, and phosphorylations by M-phase kinases are thought to positively regulate the activit...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2015.07.004
更新日期:2015-11-01 00:00:00
abstract::Low-voltage-activated T-type calcium channels are expressed in various tissues, especially in the brain, where they promote neuronal firing and are involved in slow wave sleep and absence epilepsy. While the transduction pathways by which hormones and neurotransmitters modulate high-voltage-activated calcium channels ...
journal_title:Cell calcium
pub_type: 杂志文章,评审
doi:10.1016/j.ceca.2006.04.015
更新日期:2006-08-01 00:00:00
abstract::TRPV6 belongs to the vanilloid family of the transient receptor potential channel (TRP) superfamily. This calcium-selective channel is highly expressed in the duodenum and the placenta, being responsible for calcium absorption in the body and fetus. Previous observations have suggested that TRPV6 is not only permeable...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2010.11.007
更新日期:2011-01-01 00:00:00
abstract::Aluminium lactate provokes the same modification of 45Ca(2+)-uptake by Ehrlich ascites tumour cells as does ferric lactate. The increase of uptake is metal-complex concentration-dependent, and in contrast to ferric lactate, is only partially inhibited by albumin. Under the same experimental conditions, chromic lactate...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(92)90062-w
更新日期:1992-05-01 00:00:00
abstract::As pivotal players in cellular metabolism, mitochondria have a double-faceted role in the final decision of cell fate. This is true for all cell types, but it is even more important and intriguing in the cancer setting. Mitochondria regulate cell fate in many diverse ways: through metabolism, by producing ATP and othe...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2020.102308
更新日期:2020-12-01 00:00:00
abstract::When Xenopus oocytes injected with rat brain poly(A)+RNA were voltage-clamped in a recording solution containing Ca2+, a depolarization pulse induced a transient current, ICl(Ca), which reflects calmodulin-mediated opening of endogenous Cl- channels in response to a Ca2+ influx through Ca2+ channels of brain origin. I...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(90)90008-i
更新日期:1990-04-01 00:00:00
abstract::Ca2+ is a fundamental intracellular signal that mediates a variety of disparate physiological functions often in the same cell. Ca2+ signals span a wide range of spatial and temporal scales, which endow them with the specificity required to induce defined cellular functions. Furthermore, Ca2+ signaling is highly plast...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2007.01.010
更新日期:2007-12-01 00:00:00
abstract::Several potentially life-threatening cardiovascular and respiratory disorders result in prolonged deprivation of oxygen, which in turn results in significant cellular adaptation, or remodelling. An important component of this functional adaptation arises as a direct consequence of altered ion channel expression by chr...
journal_title:Cell calcium
pub_type: 杂志文章,评审
doi:10.1016/j.ceca.2004.02.005
更新日期:2004-09-01 00:00:00
abstract::The activation of T lymphocytes, like many cells, requires a rapid rise in intracellular Ca2+ secondary to both an influx and a release from intracellular stores. The latter is activated by inositol-1,4,5-trisphosphate [Ins(1,4,5)P3]. It is controversial if inositol phosphates can also stimulate a plasma membrane Ca2+...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(93)90082-h
更新日期:1993-02-01 00:00:00
abstract::We previously found in single channel studies that ryanodine receptor (RyR) channel activity can be made insensitive to block by Mg2+ when terminal cisternae of sarcoplasmic reticulum, incorporated into planar bilayers, are treated with protein kinase A (PKA) or Ca2+/calmodulin dependent protein kinase type II (CamPK ...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(95)90064-0
更新日期:1995-09-01 00:00:00
abstract::The regulation of the Ca2+ -induced Ca2+ release (CICR) from intracellular stores is a critical step in the cardiac cycle. The inherent positive feedback of CICR should make it a self-regenerating process. It is accepted that CICR must be governed by some negative control, but its nature is still debated. We explore h...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2004.01.023
更新日期:2004-08-01 00:00:00
abstract::The sensitivity to Ca2+ of the Ca2+-dependent K+ channel can be increased by the artificial electron donor system ascorbate + phenazine-methosulphate in a variety of animal cells. In the human erythrocyte the shift from the 'low' to the 'high-affinity' state seems to depend on the reduction of a membrane component acc...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(83)90024-6
更新日期:1983-12-01 00:00:00
abstract::Corticosteroid hormones, which are released in high amounts after stress, easily pass the blood-brain-barrier. In the brain they bind to intracellular receptors which act as transcriptional regulators. These receptors are highly expressed in neurons of the hippocampal formation and the amygdala, areas that play a role...
journal_title:Cell calcium
pub_type: 杂志文章,评审
doi:10.1016/j.ceca.2011.11.002
更新日期:2012-03-01 00:00:00
abstract::Fura-2 fluorescence imaging was used to measure changes in intracellular Ca2+ concentration in individual N1E-115 neuroblastoma cells during repeated activation of M1 muscarinic receptors with carbachol. Ca2+ transients could be elicited repeatedly at 4 min intervals with little decrement as long as external Ca2+ was ...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/s0143-4160(96)90113-x
更新日期:1996-05-01 00:00:00
abstract::The peptide of HIV-1 envelope gp41 (a.a 628-683), referred to herein as P5, contains P1, a conserved galactose-specific lectin domain for binding the mucosal HIV-1-receptor, galactosyl ceramide (GalCer), as shown earlier, and a potential calcium-binding site (a.a 628-648). P1 contains contiguous epitopes recognized by...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/j.ceca.2007.04.011
更新日期:2008-01-01 00:00:00
abstract::Calcium and redox signals are presently established as essential regulators of many cellular processes. Nevertheless, we are still far from fully understanding the physiological and pathological importance of these universal second messengers. It is becoming increasingly apparent that many cellular functions are not r...
journal_title:Cell calcium
pub_type: 杂志文章,评审
doi:10.1016/j.ceca.2016.04.008
更新日期:2016-08-01 00:00:00