Abstract:
INTRODUCTION:International and Spanish guidelines recommend a 4-drug regimen in the intensive treatment of tuberculosis (TB). The aim of our study was to determine if these recommendations are followed in Spain, and the factors associated with the use of 3 drugs (standard regimen without ethambutol). METHODOLOGY:Observational, multicenter, retrospective analysis of data from patients diagnosed with TB in practically all Spanish Autonomous Communities between 2007 and 2102. Factors associated with the use of 3 drugs were analyzed using logistic regression, and odds ratios (OR) and corresponding 95% confidence intervals (CI) were calculated. RESULTS:A total of 3,189 patients were included, 1,413 (44.3%) of whom received 3 drugs. The percentage of 3-drug users among patients with positive sputum smear was 41.2%; among patients with resistance to at least 1 drug, 36.1%; among HIV-infected patients, 31.4%; and among immigrants, 24.8%. Factors associated with the use of 3 drugs were: female sex (OR=1.18; CI: 1.00-1.39); native Spanish (OR=3.09; CI: 2.58-3.70); retired (OR=1.42; CI: 1.14-1.77); homeless (OR=3.10; CI: 1.52-6.43); living alone (OR=1.62; CI: 1.11-2.36); living in a family (OR=1.97; CI: 1.48-2.65); seen by specialists in the region (OR=1.37; CI: 1.10;1.70); no HIV infection (OR=1.63; CI: 1.09-2.48); and negative sputum smear with positive culture (OR=1.59; CI: 1.25-2.02). CONCLUSIONS:A large proportion of TB patients receive intensive treatment with 3 drugs. TB treatment recommendations should be followed, both in routine clinical practice and by the National Plan for Prevention and Control of Tuberculosis in Spain.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
García-García JM,Rodrigo T,Casals M,Ruiz-Manzano J,Pascual-Pascual T,Caylà JA,Grupo de Trabajo del Programa Integrado de Investigación en Tuberculosis (PIITB).doi
10.1016/j.arbres.2015.11.007subject
Has Abstractpub_date
2016-05-01 00:00:00pages
262-8issue
5eissn
0300-2896issn
1579-2129pii
S0300-2896(15)00478-0journal_volume
52pub_type
杂志文章,多中心研究abstract:BACKGROUND:Two previous national epidemiological studies, IBERPOC in 1997 and EPISCAN in 2007, determined the COPD burden in Spain. Changes in demographics and exposure to risk factors demand the periodic update of COPD prevalence and its determinants. METHODS:EPISCAN II aimed to estimate the prevalence of COPD in the...
journal_title:Archivos de bronconeumologia
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更新日期:2021-01-01 00:00:00
abstract::We analyze the result of using a pneumological rapid-attention facility for diagnosis and immediate treatment of patients with respiratory symptoms arriving at the emergency room of University Hospital Virgen del Rocío in Seville (Spain). In the first six months the outpatient service saw 321 patients (male/female rat...
journal_title:Archivos de bronconeumologia
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abstract:OBJECTIVES:To analyze the results of thymectomy in our series of patients with myasthenia gravis (MG) and to study the influence of the most common prognostic factors. MATERIAL AND METHODS:Eighty MG patients over a period of 23 years underwent thymectomy consecutively in our hospital. Preoperative assessment included ...
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abstract:INTRODUCTION:Ergospirometry objectively quantifies exercise capacity. Up until now, the response to exercise evaluated by ergospirometry in patients with pulmonary arterial hypertension has only been described in recently diagnosed.patients. Our aim is to describe the response to exercise in patients with severe pulmon...
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abstract:UNLABELLED:The diaphragm seems to undergo adaptive structural change in chronic obstructive pulmonary disease. The possibility of obtaining muscle specimens is limited, however, particularly when respiratory function is severely affected. OBJECTIVE:To assess the viability of a new technique for obtaining diaphragm mus...
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abstract::Sixty patients diagnosed as having chronic respiratory diseases were surveyed in order to establish how many knew the name of their disease, the medications they were taking, the name of the medical specialty dedicated to treating their condition and the nature of spirometry. Only 23 patients (38%) knew the name of th...
journal_title:Archivos de bronconeumologia
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abstract:OBJECTIVE:This study assessed vena cava filter (VCF) retrieval rates and factors associated with retrieval failure in a single center cohort. METHODS:We conducted an observational retrospective cohort study. The primary endpoint was the percentage of patients whose VCF was retrieved. We performed logistic regression t...
journal_title:Archivos de bronconeumologia
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abstract::The Clinical Notes published in 2009 serve as a resource to reflect on clinical aspects relevant to different clinical entities. Through this review an attempt is likewise made to bring the reader closer to the clinical reality of our environment. ...
journal_title:Archivos de bronconeumologia
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journal_title:Archivos de bronconeumologia
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doi:10.1016/s1579-2129(07)60038-x
更新日期:2007-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60198-5
更新日期:2004-02-01 00:00:00
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journal_title:Archivos de bronconeumologia
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doi:10.1016/s0300-2896(15)30259-3
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doi:
更新日期:2007-05-01 00:00:00
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journal_title:Archivos de bronconeumologia
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更新日期:2004-11-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2014-01-01 00:00:00
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更新日期:2009-02-01 00:00:00
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更新日期:2011-01-01 00:00:00
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更新日期:2015-12-01 00:00:00
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