Abstract:
:Root-knot nematodes (RKNs) are obligate biotrophic parasites that invade plant roots and engage in prolonged and intimate relationships with their hosts. Nematode secretions, some of which have immunosuppressing activity, play essential roles in successful parasitism; however, their mechanisms of action remain largely unknown. Here, we show that the RKN-specific gene MiMsp40, cloned from Meloidogyne incognita, is expressed exclusively in subventral oesophageal gland cells and is strongly upregulated during early parasitic stages. Arabidopsis plants overexpressing MiMsp40 were more susceptible to nematode infection than were wild type plants. Conversely, the host-derived MiMsp40 RNAi suppressed nematode parasitism and/or reproduction. Moreover, overexpression of MiMsp40 in plants suppressed the deposition of callose and the expression of marker genes for bacterial elicitor elf18-triggered immunity. Transient expression of MiMsp40 prevented Bax-triggered defence-related programmed cell death. Co-agroinfiltration assays indicated that MiMsp40 also suppressed macroscopic cell death triggered by MAPK cascades or by the ETI cognate elicitors R3a/Avr3a. Together, these results demonstrate that MiMsp40 is a novel Meloidogyne-specific effector that is injected into plant cells by early parasitic stages of the nematode and that plays a role in suppressing PTI and/or ETI signals to facilitate RKN parasitism.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Niu J,Liu P,Liu Q,Chen C,Guo Q,Yin J,Yang G,Jian Hdoi
10.1038/srep19443subject
Has Abstractpub_date
2016-01-22 00:00:00pages
19443issn
2045-2322pii
srep19443journal_volume
6pub_type
杂志文章abstract::We assessed 1-year outcomes in patients with atrial fibrillation enrolled in the EurObservational Research Programme AF General Pilot Registry (EORP-AF), in relation to kidney function, as assessed by glomerular filtration rate (eGFR). In a cohort of 2398 patients (median age 69 years; 61% male), eGFR (ml/min/1.73 m(2...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究
doi:10.1038/srep30271
更新日期:2016-07-28 00:00:00
abstract::Previous studies have consistently reported an association between circulating levels of branched-chain amino acids (BCAAs) or adipokines and insulin resistance; however, the association between BCAA and adipokine levels remains to be clarified. In this cross-sectional study involving 678 participants (435 men) withou...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19388-w
更新日期:2018-01-18 00:00:00
abstract::Anhedonia, the diminished ability to experience pleasure, is a challenging negative symptom in patients with schizophrenia and can be observed in at-risk individuals with schizotypy. Deficits in hedonic processing have been postulated to be related to decreased motivation to engage in potentially rewarding events. It ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35481
更新日期:2016-10-18 00:00:00
abstract::MADS-box transcription factors widely regulate all aspects of plant growth including development and reproduction. Although the MADS-box gene family genes have been extensively characterized in many plants, they have not been studied in closely related species. In this study, 73 and 74 MADS-box genes were identified i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37897-6
更新日期:2019-02-04 00:00:00
abstract::Direct growth of MoS2 nanowalls on vapor grown carbon nanofibers (VGCNFs) has been achieved using a microwave-assisted hydrothermal (MAH) method under an acidic condition. The acidic condition was obtained through the addition of an HCl aqueous solution. We demonstrate that the HCl not only modifies the pH value for l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05805-z
更新日期:2017-07-20 00:00:00
abstract::One of the challenges that plasma research encounters is how to generate a large-scale plasma plume at atmospheric pressure. Through utilizing a third electrode biased by a direct-current voltage, a longer plasma plume is generated by a plasma jet in dielectric barrier discharge configurations. Results indicate that t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35653
更新日期:2016-10-19 00:00:00
abstract::Obesity is a major cause of type 2 diabetes mellitus (T2DM) in mammals. We have previously established a zebrafish model of diet-induced obesity (DIO zebrafish) by overfeeding Artemia. Here we created DIO zebrafish using a different method to induce T2DM. Zebrafish were overfed a commercially available fish food using...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01432-w
更新日期:2017-05-03 00:00:00
abstract::Sustainable canola production is essential to meet growing human demands for vegetable oil, biodiesel, and meal for stock feed markets. Blackleg, caused by the fungal pathogen, Leptosphaeria maculans is a devastating disease that can lead to significant yield loss in many canola production regions worldwide. Breakdown...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61211-y
更新日期:2020-03-10 00:00:00
abstract::A direct, simultaneous calculation of properties of a liquid using an ab initio electron-correlated theory has long been unthinkable. Here we present structural, dynamical, and response properties of liquid water calculated by ab initio molecular dynamics using the embedded-fragment spin-component-scaled second-order ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14358
更新日期:2015-09-24 00:00:00
abstract::Efficient mitochondrial Ca2+ uptake takes place at contact points between the ER and mitochondria, and represents a key regulator of many cell functions. In a previous study with HeLa cells, we showed that ER-to-mitochondria Ca2+ transfer increases during the early phase of ER stress induced by tunicamycin as an adapt...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36394
更新日期:2016-11-03 00:00:00
abstract::The entire recrystallisation sequence and associated crystallographic texture evolution of Mg-0.8Zn-0.2Ca (wt.%) alloy was tracked using a quasi-in-situ electron backscatter diffraction (EBSD) method. Characteristic "Rare Earth" (RE) texture was formed, originating mainly from double twins and twinning-related shear b...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43415-z
更新日期:2019-05-09 00:00:00
abstract::Bivalent (poised or paused) chromatin comprises activating and repressing histone modifications at the same location. This combination of epigenetic marks at promoter or enhancer regions keeps genes expressed at low levels but poised for rapid activation. Typically, DNA at bivalent promoters is only lowly methylated i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37393
更新日期:2016-11-23 00:00:00
abstract::Ultrasound has significantly increased safety and effectiveness in regional anesthesia. However, little is known about its clinical use. We studied clinical approaches currently used by anesthesiologists, conducted a nationwide survey, and analyzed data collected in ordered logistic regression models. All active membe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45700-3
更新日期:2019-06-24 00:00:00
abstract::In this paper we report a low complexity compression method that is suitable for compact optical scanning holography (OSH) systems with different optical settings. Our proposed method can be divided into 2 major parts. First, an automatic decision maker is applied to select the rows of holographic pixels to be scanned...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34724
更新日期:2016-10-06 00:00:00
abstract::Osthole, an active coumarin isolated from Cnidium monnieri (L.) Cusson, has long been used in China as an antipruritic herbal medicine; however, the antipruitic mechanism of osthole is unknown. We studied the molecular mechanism of osthole in histamine-dependent itch by behavioral test, Ca(2+) imaging, and electrophys...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25657
更新日期:2016-05-10 00:00:00
abstract::Rotator cuff tears are common and are associated with shoulder pain, disability, and dysfunction. Previous studies that have reported different arthroscopic techniques are controversial. A network meta-analysis with indirect and direct evidence was performed to compare the effectiveness of arthroscopic techniques for ...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-019-40641-3
更新日期:2019-03-11 00:00:00
abstract::We investigate the growth of Cu films on two different Cu seed layers: one with regular <111>-oriented grains and the other with very strong <111>-preferred orientation. It is found that densely-packed nanotwinned Cu (nt-Cu) can be grown by pulsed electroplating on the strong <111>-oriented Cu seed layer without a ran...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06123
更新日期:2014-08-19 00:00:00
abstract::Diarrhea is a leading cause of death among young mammals, especially during weaning. Here, we investigated the effects of Cathelicidin-WA (CWA) on diarrhea, intestinal morphology, inflammatory responses, epithelial barrier and microbiota in the intestine of young mammals during weaning. Piglets with clinical diarrhea ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25679
更新日期:2016-05-16 00:00:00
abstract::Fertilisation datasets collected from field experiments (n = 21) in tea-producing areas from 2016 to 2018 were used to build a quantitative evaluation of the fertility of tropical soils (QUEFTS) model to estimate nutrient uptake of tea plants, and to investigate relationships between tea yield and nutrient accumulatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57809-x
更新日期:2020-02-04 00:00:00
abstract::Hesperiidae is one of the largest families of butterflies. Our knowledge of the higher systematics on hesperiids from China is still very limited. We infer the phylogenetic relationships of the subfamilies of Chinese skippers based on three mitochondrial genes (cytochrome b (Cytb), the NADH dehydrogenase subunit 1 (ND...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11140
更新日期:2015-06-10 00:00:00
abstract::Fibrosis with excessive amounts of type I collagen is a hallmark of many solid tumours, and fibrosis is a promising target in cancer therapy, but tools for its non-invasive quantification are missing. Here we used magnetic resonance imaging with a gadolinium-based probe targeted to type I collagen (EP-3533) to image a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08838-6
更新日期:2017-08-14 00:00:00
abstract::Red mud as a waste material is produced in large quantities by the aluminum industry. Heat activation has been used to enhance sorption capacity of red mud for its beneficial reuse as an effective sorbent. In this study, heat-activated red mud (HARM) was investigated for its Cd(II) sorption capacity under various proc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31967-5
更新日期:2018-09-10 00:00:00
abstract::Restenosis remains a significant problem after angioplasty of hemodialysis vascular access. Both experimental and clinical studies have shown a protective effect of antioxidants against post-angioplasty restenosis. A prospective, randomized, feasibility study was conducted to investigate the effect of ascorbic acid to...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41598-019-47583-w
更新日期:2019-07-31 00:00:00
abstract::The heterogeneity of metabolic reactions leads to a non-uniform distribution of temperature in different parts of the living cell. The demand to study normal functioning and pathological abnormalities of cellular processes requires the development of new visualization methods. Previously, we have shown that the 35-kDa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45421-7
更新日期:2019-06-20 00:00:00
abstract::Extracellular vesicles (EVs) such as exosomes and microvesicles serve as messengers of intercellular network, allowing exchange of cellular components between cells. EVs carry lipids, proteins, and RNAs derived from their producing cells, and have potential as biomarkers specific to cell types and even cellular states...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33935
更新日期:2016-09-23 00:00:00
abstract::Recent studies have reported the ectopic expression of olfactory receptors (ORs) in non-olfactory tissues, however, their physiological roles were not well elucidated. ORs are expressed in and function in different types of cancers. Here, we identified that the H3K9me2 levels of several OR promoters decreased during d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46182
更新日期:2017-04-07 00:00:00
abstract::Activity-regulated cytoskeleton-associated protein (Arc; also known as Arg3.1) is an immediate early gene product that is transcribed in dendritic spines and, to date, has been best characterized as a positive regulator of AMPAR endocytosis during long-term depression (LTD) through interaction with endocytic proteins....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32821-4
更新日期:2018-10-02 00:00:00
abstract::Blockage of pores by particles is found in many processes, including filtration and oil extraction. We present filtration experiments through a linear array of ten channels with one dimension which is sub-micron, through which a dilute dispersion of Brownian polystyrene spheres flows under the action of a fixed pressu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30389-7
更新日期:2018-08-20 00:00:00
abstract::To match the relentless pursuit of three research hot points - efficient solar utilization, green and sustainable remediation of wastewater and advanced oxidation processes, solar-mediated thermo-electrochemical oxidation of surfactant was proposed and developed for green remediation of surfactant wastewater. The sola...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44683
更新日期:2017-03-15 00:00:00
abstract::The majority of surveys on food webs of aquatic ecosystems have been conducted during the day owning to difficulties in sampling animals at night. In this study, to examine diurnal changes in predator-prey interactions in a temperate seagrass Zostera marina bed, a quantitative day/night survey of fish, the dominant an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04217-3
更新日期:2017-06-20 00:00:00