Factors Associated With Protein-energy Malnutrition in Chronic Liver Disease: Analysis Using Indirect Calorimetry.

Abstract:

:We aimed to elucidate the incidence of protein-energy malnutrition (PEM) in patients with chronic liver disease and to identify factors linked to the presence of PEM.A total of 432 patients with chronic liver disease were analyzed in the current analysis. We defined patients with serum albumin level of ≤3.5 g/dL and nonprotein respiratory quotient (npRQ) value using indirect calorimetry less than 0.85 as those with PEM. We compared between patients with PEM and those without PEM in baseline characteristics and examined factors linked to the presence of PEM using univariate and multivariate analyses.There are 216 patients with chronic hepatitis, 123 with Child-Pugh A, 80 with Child-Pugh B, and 13 with Child-Pugh C. Six patients (2.8%) had PEM in patients with chronic hepatitis, 17 (13.8%) in patients with Child-Pugh A, 42 (52.5%) in patients with Child-Pugh B, and 10 (76.9%) in patients with Child-Pugh C (P < 0.001). Multivariate analysis revealed that Child-Pugh classification (P < 0.001), age ≥64 years (P = 0.0428), aspartate aminotransferase (AST) ≥40 IU/L (P = 0.0023), and branched-chain amino acid to tyrosine ratio (BTR) ≤5.2 (P = 0.0328) were independent predictors linked to the presence of PEM. On the basis of numbers of above risk factors (age, AST, and BTR), the proportions of patients with PEM were well stratified especially in patients with early chronic hepatitis or Child-Pugh A (n = 339, P < 0.0001), while the proportions of patients with PEM tended to be well stratified in patients with Child-Pugh B or C (n = 93, P = 0.0673).Age, AST, and BTR can be useful markers for identifying PEM especially in patients with early stage of chronic liver disease.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Nishikawa H,Yoh K,Enomoto H,Iwata Y,Kishino K,Shimono Y,Hasegawa K,Nakano C,Takata R,Nishimura T,Aizawa N,Sakai Y,Ikeda N,Takashima T,Ishii A,Iijima H,Nishiguchi S

doi

10.1097/MD.0000000000002442

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

e2442

issue

2

eissn

0025-7974

issn

1536-5964

pii

00005792-201601120-00038

journal_volume

95

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Olfactory function and quality of life following microscopic endonasal transsphenoidal pituitary surgery.

    abstract::Olfactory outcomes as well as oronasal postoperative complications of transsphenoidal pituitary surgery have not been well studied. The objective of this study was to investigate nasal symptoms including olfactory function as well as quality of life following transsphenoidal pituitary surgery. The study is designed as...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000465

    authors: Wang S,Chen Y,Li J,Wei L,Wang R

    更新日期:2015-01-01 00:00:00

  • Gemcitabine plus S-1 for metastatic pancreatic cancer.

    abstract::To investigate the treatment effects of gemcitabine plus S-1 (GS) for metastatic pancreatic cancer in our institution.Data from 41 patients with metastatic pancreatic cancer treated with GS regimen in West China Hospital, Sichuan University were reviewed. The therapeutic efficacy and toxicity were evaluated. The influ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012836

    authors: Zhu H,Yi C,Zhao Y,Gou H

    更新日期:2018-10-01 00:00:00

  • Changes of quality of life and cognitive function in individuals with Internet gaming disorder: A 6-month follow-up.

    abstract::Internet gaming disorder (IGD) contributes to poor quality of life (QOL) and cognitive dysfunction and is increasingly recognized as a social problem in various countries. However, no evidence exists to determine whether QOL and cognitive dysfunction stabilize after appropriate management. The present study addressed ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005695

    authors: Lim JA,Lee JY,Jung HY,Sohn BK,Choi SW,Kim YJ,Kim DJ,Choi JS

    更新日期:2016-12-01 00:00:00

  • Noncancer-Related Health Events and Mortality in Head and Neck Cancer Patients After Definitive Radiotherapy: A Prospective Study.

    abstract::The survival of patients with head and neck squamous cell carcinoma (HNSCC) can be affected not only by progression of the original cancer or occurrence of a second cancer but also by noncancer health event (NCHE). In this study, we evaluated the prognostic significance of early NCHEs in HNSCC patients after definitiv...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003403

    authors: Kang HS,Roh JL,Kim SB,Choi SH,Nam SY,Kim SY

    更新日期:2016-05-01 00:00:00

  • The Effects of Bevacizumab in Augmenting Trabeculectomy for Glaucoma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    abstract::The aim of the study was to assess the effects of bevacizumab in augmenting trabeculectomy for glaucoma. We searched the databases of Cochrane Library, PubMed, Embase, CNKI, and VIP. All the databases were retrieved from the time databases established to September, 2015. The keywords we used were as follows: "bevacizu...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000003223

    authors: Liu X,Du L,Li N

    更新日期:2016-04-01 00:00:00

  • Superb microvascular imaging evaluating joint lesion scores in rheumatoid arthritis compared with power Doppler imaging: A meta-analysis.

    abstract:BACKGROUND:To compare superb microvascular imaging with power Doppler imaging for evaluating joint lesion scores in rheumatoid arthritis based on high quality clinical cohort or case control studies. METHODS:We searched Medline (via PubMed), Web of Science, Cochrane Library, Embase, and Chinese Biomedical Literature D...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000022185

    authors: Lin M,Wang C

    更新日期:2020-09-11 00:00:00

  • Diagnostic value of radionuclide in bone metastasis after breast cancer surgery: A protocol of systematic review.

    abstract:BACKGROUND:The objective of this study is to evaluate the accuracy of radionuclide in diagnosis of bone metastasis (BM) after breast cancer surgery (BCS). METHODS:The electronic databases (Cochrane Library, MEDLINE, EMBASE, Web of Science, CBM, and CNKI) will be systematically and comprehensively searched until June 1...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021585

    authors: Lian QX,Zhao W,Li G,Jin LJ,Nie HJ

    更新日期:2020-08-14 00:00:00

  • Survival time and prognostic factors of patients with initial noncurative colorectal liver metastases.

    abstract::The true survival benefit of different curative strategies involving type of operative procedure and timing for patients with initial noncurative colorectal liver metastases remains uncertain. The goal of this study was to examine the effect of primary tumor resection on patients' survival and to clarify the predictiv...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008831

    authors: Liu Q,Hao L,Lou Z,Gao X,Gong H,Hong Y,Fu C,Zhang W

    更新日期:2017-12-01 00:00:00

  • Assessment of ankle and hindfoot stability and joint pressures using a human cadaveric model of a large lateral talar process excision: a biomechanical study.

    abstract::Lateral talar process fragment excision may be followed by hindfoot instability and altered biomechanics. There is controversy regarding the ideal fragment size for internal fixation versus excision and a concern that excision of a large fragment may lead to significant instability. The aim of this study was to assess...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000606

    authors: Sands A,White C,Blankstein M,Zderic I,Wahl D,Ernst M,Windolf M,Hagen JE,Richards RG,Stoffel K,Gueorguiev B

    更新日期:2015-03-01 00:00:00

  • Feasibility of measuring urethral pressure during female midurethral slings: Case report.

    abstract:RATIONALE:Stress urinary incontinence (SUI) refers to the involuntary leakage of urine when abdominal pressure increases. Midurethral slings (MUS) have become the main surgical method for treating SUI, but no quantitative standard for the degree of sling tightness during operation exists. We achieved this quantitative ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021100

    authors: Meng LF,Wang M,Zhang W,Liu XD,Zhang YG

    更新日期:2020-07-10 00:00:00

  • Primary hepatic ectopic pregnancy in a patient with polycystic ovary syndrome: A case report.

    abstract:RATIONALE:Hepatic ectopic pregnancy is an extremely rare ectopic pregnancy. This study aimed to report a case of primary hepatic pregnancy in a patient with polycystic syndrome. PATIENT CONCERNS:A 30-year-old woman presented with vaginal bleeding after 63 days of amenorrhea. DIAGNOSIS:The patient was initially diagno...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019649

    authors: Zhang N,Yang L,Wang Y,Li X,Zhang C,Xu J

    更新日期:2020-03-01 00:00:00

  • A case report of pulmonary arterial hypertension in pregnancy and complications of anticoagulation therapy.

    abstract:RATIONALE:Treprostinil, a potent vasodilator, is the treatment of choice for severe pulmonary arterial hypertension (PAH) during pregnancy. Its inhibition of platelet aggregation increases the risk of hemorrhage. In addition, anticoagulation therapy is widely used in pregnancy with PAH due to the hypercoagulable state....

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011810

    authors: Xiang Y,Li J,Sun Y

    更新日期:2018-08-01 00:00:00

  • Predictive Significance of a New Prognostic Score for Patients With Diffuse Large B-Cell Lymphoma in the Interim-Positron Emission Tomography Findings.

    abstract::We hypothesized that the objective treatment response of patients with diffuse large B-cell lymphoma (DLBCL) was affected by many factors such as pathophysiological, biological, and pharmaceutical mechanisms. This retrospective study aimed to evaluate the predictive significance of clinical prognostic factors and inte...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002808

    authors: Kong Y,Qu L,Li Y,Liu D,Lv X,Han J

    更新日期:2016-02-01 00:00:00

  • Reversible severe fatty liver induced by capecitabine: A case report.

    abstract:RATIONALE:Capecitabine (CAP) is a chemotherapeutic agent used to treat breast and gastrointestinal cancers. The most common adverse reactions of CAP primarily included gastrointestinal and dermatological effects. Whereas, the CAP-induced fatty liver had never been reported. PATIENT CONCERNS:In this study, a-69-year ol...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008547

    authors: Jiang Y,He Q,Li S,Shi C,Yang X

    更新日期:2017-11-01 00:00:00

  • Efficacy and safety of traditional Chinese medicine for erosive oral lichen planus: A protocol for systematic review and meta analysis.

    abstract:BACKGROUND:Oral lichen planus (OLP) is a common disease among oral mucous membrane diseases. Erosive oral lichen planus (EOLP) is a type of OLP, it has a potential tendency of cancerization. There have been some randomized controlled trials (RCTs) using Traditional Chinese Medicine (TCM) to treat EOLP. No systematic re...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000023375

    authors: You Y,Huang X,Chen Y,You Y

    更新日期:2020-11-25 00:00:00

  • Candidate genes investigation for severe nonalcoholic fatty liver disease based on bioinformatics analysis.

    abstract:BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver condition worldwide. However, its etiology and fundamental pathophysiology for the disease process are poorly understood. In this study, we thus used bioinformatics to identify candidate genes potentially causative of severe NAFLD. ME...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007743

    authors: Qi S,Wang C,Li C,Wang P,Liu M

    更新日期:2017-08-01 00:00:00

  • Sinonasal involvement in sarcoidosis: a case-control study of 20 patients.

    abstract::We conducted a retrospective single-center study to describe the clinical features of sinonasal sarcoidosis (SNS) and to determine whether SNS is associated with a particular clinical phenotype of sarcoidosis. Twenty patients with histologically proven SNS (men/women, 7/13; mean age, 32 +/- 9 yr) were compared with co...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/01.md.0000236955.79966.07

    authors: Aubart FC,Ouayoun M,Brauner M,Attali P,Kambouchner M,Valeyre D,Nunes H

    更新日期:2006-11-01 00:00:00

  • Rectal nonsteroidal anti-inflammatory drugs and pancreatic stents in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: A network meta-analysis.

    abstract:BACKGROUND:100 mg rectal nonsteroidal anti-inflammatory drugs (NSAIDs) and pancreatic stents both significantly reduce the incidence of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. Direct comparison of randomized controlled trials (RCTs) between them in high-risk patients is absent. We condu...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000022672

    authors: Shou-Xin Y,Shuai H,Fan-Guo K,Xing-Yuan D,Jia-Guo H,Tao P,Lin Q,Yan-Sheng S,Ting-Ting Y,Jing Z,Fang L,Hao-Liang Q,Man L

    更新日期:2020-10-16 00:00:00

  • Posterior occipital intramuscular hemangioma mimicking arteriovenous malformation: Case report.

    abstract:RATIONALE:Intermuscular hemangioma (IH) usually occurs in the muscles of the limbs and trunk, but can rarely occur in the occipital region. IH in the occipital region is easily misdiagnosed as arteriovenous malformation (AVM). PATIENT CONCERNS:A 31-year-old woman had a right occipital mass for 5 months without pulsati...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014678

    authors: Chen H,Xu B,Wang G,Guo Y,Hou K,Yu J

    更新日期:2019-03-01 00:00:00

  • Case report: A non-obstructive azoospermia patient with heat shock factor-2 mutation.

    abstract:RATIONALE:Infertility is a common medical condition that affects nearly 15% of the world population. Non-obstructive azoospermia (NOA) is one of the most severe forms of male infertility. Some common structural variants, single nucleotide polymorphisms (SNPs), and genetic factors were reported to be associated with NOA...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021107

    authors: Zhao H,Zhang H,Xi Q,Li L,Zhu H,Hu X,Liu R

    更新日期:2020-07-31 00:00:00

  • Uterine size and volume are associated with higher live birth rate in patients undergoing assisted reproduction technology: A prospective cohort study.

    abstract::To investigate how uterine size and volume are associated with live birth rate in patients undergoing assisted reproduction technology.This prospective cohort study was conducted at the Reproductive Medicine Centre from January 2010 to May 2017. Multivariate binary logistic regression was used to evaluate the relation...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017966

    authors: Gao H,Liu DE,Li Y,Tang J,Wu X,Tan H

    更新日期:2019-11-01 00:00:00

  • Alveolar hemorrhage syndromes: diffuse microvascular lung hemorrhage in immune and idiopathic disorders.

    abstract::We have reviewed the alveolar hemorrhage (AH) syndromes, defined as immune or idiopathic disorders associated with diffuse microvascular hemorrhage into the acinar portion of the lung. The disorders that are most often associated with AH include antibasement membrane antibodies (ABMA) disease, idiopathic pulmonary hem...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Leatherman JW,Davies SF,Hoidal JR

    更新日期:1984-11-01 00:00:00

  • Extracorporeal membrane oxygenation support in post-traumatic cardiopulmonary failure: A 10-year single institutional experience.

    abstract::Patients with multiple traumas associated with cardiopulmonary failure have a high mortality rate; however, such patients can be temporarily stabilized using extracorporeal membrane oxygenation (ECMO), providing a bridge to rescue therapy. Using a retrospective study design, we aimed to clarify the prognostic factors ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006067

    authors: Lin CY,Tsai FC,Lee HA,Tseng YH

    更新日期:2017-02-01 00:00:00

  • Ultrasound is highly specific in diagnosing compensated cirrhosis in chronic hepatitis C patients in real world clinical practice.

    abstract::Ultrasound is routinely used during the evaluation of liver cirrhosis. Inter-observer variability is considered a major drawback. This retrospective study investigated the accuracy of ultrasound in diagnosing compensated cirrhosis (i.e., modified Knodell F3, F4) in chronic hepatitis C (CHC) patients in real world clin...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016270

    authors: Yen YH,Kuo FY,Chen CH,Hu TH,Lu SN,Wang JH,Hung CH

    更新日期:2019-07-01 00:00:00

  • Adjuvant endocrine therapy alone in patients with node-positive, luminal A type breast cancer.

    abstract::Luminal A breast cancer has a much better prognosis than other subtypes, with a low risk of local or regional recurrence. However, there is controversy around under- versus overtreatment with regard to adjuvant treatment of node-positive, luminal A breast cancer. The purpose of this study was to identify whether adjuv...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006777

    authors: Park S,Lee SK,Paik HJ,Ryu JM,Kim I,Bae SY,Yu J,Kim SW,Lee JE,Nam SJ

    更新日期:2017-06-01 00:00:00

  • Identification of key genes in calcific aortic valve disease by integrated bioinformatics analysis.

    abstract::Calcific aortic valve disease (CAVD) is highly prevalent in our aging world and has no effective pharmaceutical treatment. Intense efforts have been made but the underlying molecular mechanisms of CAVD are still unclear.This study was designed to identify the critical genes and pathways in CAVD by bioinformatics analy...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021286

    authors: Teng P,Xu X,Ni C,Yan H,Sun Q,Zhang E,Ni Y

    更新日期:2020-07-17 00:00:00

  • Perioperative Blood Glucose Levels 

    abstract::Hyperglycemia is common during and after Coronary Artery Bypass Graft Surgery (CABGS) and has been shown to be associated with poor clinical outcomes. In this study, we hypothesized that a moderate perioperative mean blood glucose level of <150 mg/dL improves long-term survival in cardiac surgery patients. We conducte...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002035

    authors: Mansur A,Popov AF,Hanna AA,Bergmann I,Brandes IF,Beissbarth T,Bauer M,Hinz J

    更新日期:2015-11-01 00:00:00

  • Assessment of mental health among nursing staff at different levels.

    abstract::To assess the mental health of nurses and to find the post responsibility and psychological status of clinical nurses.A total of 447 nursing staff at different levels in a teaching hospital was assessed by nursing post responsibility scale and mental symptom checklist (SCL-90) then compared with each other. The study ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019049

    authors: Du ML,Deng WX,Sun W,Chien CW,Tung TH,Zou XC

    更新日期:2020-02-01 00:00:00

  • The Relationship Between Educational Years and Phonemic Verbal Fluency (PVF) and Semantic Verbal Fluency (SVF) Tasks in Spanish Patients Diagnosed With Schizophrenia, Bipolar Disorder, and Psychotic Bipolar Disorder.

    abstract::Semantic and verbal fluency tasks are widely used as a measure of frontal capacities. It has been well described in literature that patients affected by schizophrenic and bipolar disorders present a worse execution in these tasks. Some authors have also noted the importance of educational years. Our objective is to an...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001596

    authors: García-Laredo E,Maestú F,Castellanos MÁ,Molina JD,Peréz-Moreno E

    更新日期:2015-09-01 00:00:00

  • The burden of air pollution and weather condition on daily respiratory deaths among older adults in China, Jinan from 2011 to 2017.

    abstract::The health effects of short-term exposure to air pollutants on respiratory deaths and its modifiers such as meteorological indexes have been widely investigated. However, most of the previous studies are limited to single pollutants or total respiratory deaths, and their findings are inconsistent.To comprehensively ex...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014694

    authors: Song WM,Liu Y,Liu JY,Tao NN,Li YF,Liu Y,Wang LX,Li HC

    更新日期:2019-03-01 00:00:00