Support for the Microgenderome: Associations in a Human Clinical Population.

abstract：:CD74 is expressed on the cell surface of pulmonary macrophages and contributes to macrophage migration inhibitory factor (MIF)-induced inflammatory response in acute lung injury (ALI). A circulating form of CD74 (soluble CD74, sCD74) was recently discovered in autoimmune liver disease. Using two murine ALI models and ...

journal_title：Scientific reports

authors： Wu G,Sun Y,Wang K,Chen Z,Wang X,Chang F,Li T,Feng P,Xia Z

更新日期：2016-07-22 00:00:00

abstract：:Hyperspectral imaging technology is playing an increasingly important role in the fields of food analysis, medicine and biotechnology. To improve the speed of operation and increase the light throughput in a compact equipment structure, a Fourier transform hyperspectral imaging system based on a single-pixel technique...

journal_title：Scientific reports

authors： Jin S,Hui W,Wang Y,Huang K,Shi Q,Ying C,Liu D,Ye Q,Zhou W,Tian J

更新日期：2017-03-24 00:00:00

abstract：:We aimed to investigate the association of smoking and physical exercise on ventricular function and structure, determined by cardiac magnetic resonance imaging (CMR), in subjects without known cardiovascular diseases. A total of 381 participants (median age 57 years) of the Cooperative Health Research in the Region o...

journal_title：Scientific reports

authors： Schafnitzel A,Lorbeer R,Bayerl C,Patscheider H,Auweter SD,Meisinger C,Heier M,Ertl-Wagner B,Reiser M,Peters A,Bamberg F,Hetterich H

更新日期：2019-12-09 00:00:00

abstract：:Locusts have excellent jumping and kicking abilities to survive in nature, which are achieved through the energy storage and release processes occurring in cuticles, especially in the semi-lunar processes (SLP) at the femorotibial joints. As yet, however, the strain energy-storage mechanisms of the SLP cuticles remain...

journal_title：Scientific reports

authors： Wan C,Hao Z,Feng X

更新日期：2016-10-17 00:00:00

abstract：:Globally, a small percentage of oil is recovered from reservoirs using primary and secondary recovery mechanisms, and thus a major focus of the oil industry is toward developing new technologies to increase recovery. Many new technologies utilize surfactants, macromolecules, and even nanoparticles, which are difficult...

journal_title：Scientific reports

authors： Eichmann SL,Burnham NA

更新日期：2017-09-14 00:00:00

abstract：:Dynamical polarization of nuclear spin ensembles is of central importance for magnetic resonance studies, precision sensing and for applications in quantum information theory. Here we propose a scheme to generate long-lived singlet pairs in an unpolarized nuclear spin ensemble which is dipolar coupled to the electron ...

journal_title：Scientific reports

authors： Greiner JN,Dasari DBR,Wrachtrup J

更新日期：2017-04-03 00:00:00

abstract：:A frequency reconfigurable dipole antenna based on a silicon radiator is presented. The silicon radiator is activated with the aid of highly dense solid-state plasma by injecting carriers into the intrinsic region of p-i-n diodes. The fabrication and design guideline of the reconfigurable dipole antenna with this plas...

journal_title：Scientific reports

authors： Kim DJ,Jo ES,Cho YK,Hur J,Kim CK,Kim CH,Park B,Kim D,Choi YK

更新日期：2018-10-09 00:00:00

abstract：:Comprehensive and accurate characterization of brain metabolome is fundamental to brain science, but has been hindered by technical limitations. We profiled the brain metabolome in male Wistar rats at different ages (day 1 to week 111) using high-sensitivity and high-resolution mass spectrometry. Totally 380 metabolit...

journal_title：Scientific reports

authors： Zheng X,Chen T,Zhao A,Wang X,Xie G,Huang F,Liu J,Zhao Q,Wang S,Wang C,Zhou M,Panee J,He Z,Jia W

更新日期：2016-04-11 00:00:00

abstract：:The early replication of some orally-acquired prion strains upon stromal-derived follicular dendritic cells (FDC) within the small intestinal Peyer's patches is essential to establish host infection, and for the disease to efficiently spread to the brain. Factors that influence the early accumulation of prions in Peye...

journal_title：Scientific reports

authors： Sánchez-Quintero A,Bradford BM,Maizels R,Donaldson DS,Mabbott NA

更新日期：2019-04-30 00:00:00

abstract：:We characterized the microstructural response of the myocardium to cardiovascular disease using diffusion tensor imaging (DTI) and performed histological validation by intact, un-sectioned, three-dimensional (3D) histology using a tissue-clearing technique. The approach was validated in normal (n = 7) and ischemic (n ...

journal_title：Scientific reports

authors： Lee SE,Nguyen C,Yoon J,Chang HJ,Kim S,Kim CH,Li D

更新日期：2018-04-27 00:00:00

abstract：:Although Hepatitis B virus (HBV) X gene mutations are frequently detected in HBV-related human hepatocellular carcinoma (HCC) patients, causative HBx mutations in the development of HCC have not yet been determined. We herein identified C1485T and C1653T mutations in the HBx gene as independent risk of HCC for HBV thr...

journal_title：Scientific reports

authors： Hagiwara S,Nishida N,Park AM,Komeda Y,Sakurai T,Watanabe T,Kudo M

更新日期：2017-09-05 00:00:00

abstract：:The Coronavirus Disease 2019 (COVID-19) pandemic continues to have a devastating effect on the health and well-being of the global population. A critical step in the fight against COVID-19 is effective screening of infected patients, with one of the key screening approaches being radiology examination using chest radi...

journal_title：Scientific reports

authors： Wang L,Lin ZQ,Wong A

更新日期：2020-11-11 00:00:00

abstract：:Growth cones of extending axons navigate to correct targets by sensing a guidance cue gradient via membrane protein receptors. Although most signaling mechanisms have been clarified using an in vitro approach, it is still difficult to investigate the growth cone behavior in complicated extracellular environment of liv...

journal_title：Scientific reports

authors： Endo M,Hattori M,Toriyabe H,Ohno H,Kamiguchi H,Iino Y,Ozawa T

更新日期：2016-04-07 00:00:00

abstract：:To understand the impact of PIK3CA mutations on clinical characteristics and treatment response to epidermal growth factor tyrosine kinase inhibitors (EGFR TKIs) of lung adenocarcinoma, we examined PIK3CA and EGFR mutations in lung adenocarcinoma patients, and analyzed their clinical outcomes. Surgically excised tumor...

journal_title：Scientific reports

authors： Wu SG,Chang YL,Yu CJ,Yang PC,Shih JY

更新日期：2016-10-13 00:00:00

abstract：:The natural bacterial diversity is regarded as a treasure trove for natural products. However, accessing complex cell mixtures derived from environmental samples in standardized high-throughput screenings is challenging. Here, we present a droplet-based microfluidic platform for ultrahigh-throughput screenings able to...

journal_title：Scientific reports

authors： Mahler L,Wink K,Beulig RJ,Scherlach K,Tovar M,Zang E,Martin K,Hertweck C,Belder D,Roth M

更新日期：2018-08-30 00:00:00

abstract：:Neurofeedback is a strong direct training method for brain function, wherein brain activity patterns are measured and displayed as feedback, and trainees try to stabilize the feedback signal onto certain desirable states to regulate their own mental states. Here, we introduce a novel neurofeedback method, using the mi...

journal_title：Scientific reports

authors： Chang M,Iizuka H,Naruse Y,Ando H,Maeda T

更新日期：2014-10-24 00:00:00

abstract：:Several studies have shown that the 'poor' sperm DNA quality appears to be an important factor affecting male reproductive ability. In the case of sperm cells from males with the correct somatic karyotype but with deficient spermatogenesis, resulting in a high degree of sperm DNA fragmentation, we observed changes in ...

journal_title：Scientific reports

authors： Wiland E,Fraczek M,Olszewska M,Kurpisz M

更新日期：2016-08-25 00:00:00

abstract：:Most complex systems are intrinsically dynamic in nature. The evolution of a dynamic complex system is typically represented as a sequence of snapshots, where each snapshot describes the configuration of the system at a particular instant of time. This is often done by using constant intervals but a better approach wo...

journal_title：Scientific reports

authors： Darst RK,Granell C,Arenas A,Gómez S,Saramäki J,Fortunato S

更新日期：2016-12-22 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Abusara Z,Andrews SHJ,Von Kossel M,Herzog W

更新日期：2019-04-09 00:00:00

abstract：:The natural ligand 17β-estradiol (E2) is so far believed to induce a unique agonist-bound active conformation in the ligand binding domain (LBD) of the estrogen receptors (ERs). Both subtypes, ERα and ERβ, are transcriptionally activated in the presence of E2 with ERβ being somewhat less active than ERα under similar ...

journal_title：Scientific reports

authors： Souza PCT,Textor LC,Melo DC,Nascimento AS,Skaf MS,Polikarpov I

更新日期：2017-06-14 00:00:00

abstract：:An intensified and continuous West Nile virus (WNV) spread across northern Italy has been observed since 2008, which caused more than one hundred reported human infections until 2016. Veneto is one of the Italian regions where WNV is considered endemic, and the greatest intensity of circulation was observed during 201...

journal_title：Scientific reports

authors： Marini G,Rosà R,Pugliese A,Rizzoli A,Rizzo C,Russo F,Montarsi F,Capelli G

更新日期：2018-09-18 00:00:00

abstract：:While previous studies separately demonstrate EEG spectral modulations during speech preparation and ERP responses to the listened speech, it is unclear whether these responses are related on a trial-by-trial basis between a speaker and listener. In order to determine whether these responses are related in real-time, ...

journal_title：Scientific reports

authors： Bridwell DA,Henderson S,Sorge M,Plis S,Calhoun VD

更新日期：2018-08-27 00:00:00

abstract：:The migration of oligodendrocyte progenitor cells (OPCs) to the white matter is an indispensable requirement for an intact brain function. The mechanism of cell migration in general is not yet completely understood. Nevertheless, evidence is accumulating that besides the coordinated rearrangement of the cytoskeleton, ...

journal_title：Scientific reports

authors： Happel P,Möller K,Schwering NK,Dietzel ID

更新日期：2013-01-01 00:00:00

abstract：:Auricle defects are important and common occurrences in forensic medicine. The accurate measurement and assessment of auricle defects is key to identifying and evaluating injury, and the currently available methods are known to be labor intensive and inaccurate. In this paper, we introduce an identification and docume...

journal_title：Scientific reports

authors： Zhan G,Han L,Li Z,Liu Z,Fu J,Zhong K

更新日期：2018-02-12 00:00:00

abstract：:Emerging evidence demonstrates the importance of sufficient vitamin D (1α, 25-dihydroxyvitamin D3) levels during early life stage development with deficiencies associated with long-term effects into adulthood. While vitamin D has traditionally been associated with mineral ion homeostasis, accumulating evidence suggest...

journal_title：Scientific reports

authors： Knuth MM,Mahapatra D,Jima D,Wan D,Hammock BD,Law M,Kullman SW

更新日期：2020-09-29 00:00:00

abstract：:Humans are good at selectively listening to specific target conversations, even in the presence of multiple concurrent speakers. In our research, we study how auditory-visual cues modulate this selective listening. We do so by using immersive Virtual Reality technologies with spatialized audio. Exposing 32 participant...

journal_title：Scientific reports

authors： Gonzalez-Franco M,Maselli A,Florencio D,Smolyanskiy N,Zhang Z

更新日期：2017-06-19 00:00:00

abstract：:Significant technical and optical advances are required for intraoperative optical coherence tomography (OCT) to be utilized during otological surgeries. Integrating OCT with surgical microscopy makes it possible to evaluate soft tissue in real-time and at a high resolution. Herein, we describe an augmented-reality, i...

journal_title：Scientific reports

authors： Lee J,Wijesinghe RE,Jeon D,Kim P,Choung YH,Jang JH,Jeon M,Kim J

更新日期：2018-11-27 00:00:00

abstract：:Macro-fungi play important roles in the soil elemental cycle in terrestrial ecosystems. Many researchers have focused on the interactions between mycorrhizal fungi and host plants, whilst comparatively few studies aim to characterise the relationships between macro-fungi and bacteria in situ. In this study, we detecte...

journal_title：Scientific reports

authors： Liu Y,Sun Q,Li J,Lian B

更新日期：2018-08-03 00:00:00

abstract：:Target-guided synthesis is an approach to drug discovery that allows the target to self-assemble its own binding agents. So far, target-guided synthesis and especially in situ click chemistry have attracted extensive attention and have led to the identification of highly potent inhibitors for proteins. In this study, ...

journal_title：Scientific reports

authors： Hu MH,Chen X,Chen SB,Ou TM,Yao M,Gu LQ,Huang ZS,Tan JH

更新日期：2015-11-25 00:00:00

abstract：:The importance of metallurgy for social and economic development is indisputable. Although copper (Cu) was essential for the wealth of pre- and post-colonial societies in the Andes, the onset of extensive Cu metallurgy in South America is still debated. Comprehensive archaeological findings point to first sophisticate...

journal_title：Scientific reports

authors： Eichler A,Gramlich G,Kellerhals T,Tobler L,Rehren T,Schwikowski M

更新日期：2017-01-31 00:00:00