Abstract:
PURPOSE:Results from epidemiologic studies on coffee consumption and the risk of cutaneous melanoma are inconsistent. We conducted a meta-analysis to assess the associations between the consumption of total coffee, caffeinated coffee and decaffeinated coffee and the risk of cutaneous melanoma, respectively. METHODS:A literature search was performed in PubMed, Web of Science and EMBASE for relevant articles published up to August 2015. Pooled relative risks (RRs) with 95 % confidence intervals (CIs) were calculated with a random-effects model. Dose-response relationship was assessed by restricted cubic spline. RESULTS:Twelve studies involving 832,956 participants for total coffee consumption, 5 studies involving 717,151 participants for caffeinated coffee consumption and 6 studies involving 718,231 participants for decaffeinated coffee consumption were included in this meta-analysis. Compared with the lowest level of consumption, the pooled RRs were 0.80 (95 % CI 0.69-0.93, I (2) = 53.5 %), 0.85 (95 % CI 0.71-1.01, I (2) = 65.0 %) and 0.92 (95 % CI 0.81-1.05, I (2) = 0.0 %) for the consumption of total coffee, caffeinated coffee and decaffeinated coffee, respectively. In subgroup analysis by study design, the pooled RRs in cohort studies and case-control studies were 0.83 (95 % CI 0.72-0.97) and 0.74 (95 % CI 0.51-1.07) for total coffee consumption, respectively. Dose-response analysis suggested cutaneous melanoma risk decreased by 3 % [0.97 (0.93-1.00)] and 4 % [0.96 (0.92-1.01)] for 1 cup/day increment of total coffee and caffeinated coffee consumption, respectively. CONCLUSIONS:This meta-analysis suggests that coffee consumption may reduce the risk of cutaneous melanoma.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Wang J,Li X,Zhang Ddoi
10.1007/s00394-015-1139-zsubject
Has Abstractpub_date
2016-06-01 00:00:00pages
1317-29issue
4eissn
1436-6207issn
1436-6215pii
10.1007/s00394-015-1139-zjournal_volume
55pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:Previous studies have described an important selenium deficiency in a mountain region (Glanle) in the west of Ivory Coast. AIM OF THE STUDY:To assess the antioxidant capacity of subjects from a selenium deficient area in Ivory Coast (Glanle region). METHODS:This study involved 57 subjects, 18 to 69 years o...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-004-0484-0
更新日期:2004-12-01 00:00:00
abstract:PURPOSE:Troxerutin (TXER), a trihydroxyethylated derivative of the natural bioflavonoid rutin, abundantly found in tea, various fruits and vegetables, is known to exhibit ample pharmacological properties. In the present investigation, we examined the antineoplastic, therapeutic efficacy and furthermore the possible mec...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-016-1275-0
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:Ellagitannins are high molecular weight polyphenols present in high quantities in various food products. They are metabolized by human and animal gut microbiota to postbiotic metabolites-urolithins, bioavailable molecules of a low molecular weight. Following absorption in the gut, urolithins rapidly undergo pha...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02386-y
更新日期:2020-09-22 00:00:00
abstract:INTRODUCTION:The objective of this paper was to evaluate the relationship between urinary concentrations of InsP6, bone mass loss and risk fracture in postmenopausal women. MATERIALS AND METHODS:A total of 157 postmenopausal women were included in the study: 70 had low (≤0.76 μM), 42 intermediate (0.76-1.42 μM) and 45...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章
doi:10.1007/s00394-012-0377-6
更新日期:2013-03-01 00:00:00
abstract::Nutrition and lifestyle, particularly over-nutrition and lack of exercise, promote the progression and pathogenesis of obesity and metabolic diseases. Nutrition is likely the most important environmental factor that modulates the expression of genes involved in metabolic pathways and a variety of phenotypes associated...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-014-0654-7
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:The aim of the current study was to determine the incorporation of cis (c) 9, trans (t) 11-conjugated linoleic acid (CLA) and t10, c12-CLA into porcine erythrocytes-both isomers were supplemented in equal proportions. METHODS:The study group consisted of 16 piglets randomly assigned into experimental and contr...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-013-0618-3
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:Protein-restricted diet during pregnancy is related to oxidative stress and, as a consequence, damage to nephrogenesis. We investigated the effects of vinifera grape skin extract (ACH09)-derived polyphenols on preserving renal morphology of maternal protein-restricted 1-day-old offspring. METHODS:Female C57/Bl...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0963-5
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Green tea is thought to possess many beneficial effects on human health. However, the extent of green tea polyphenol biotransformation may affect its proposed therapeutic effects. Catechol-O-methyltransferase (COMT), the enzyme responsible for polyphenolic methylation, has a common polymorphism in the genetic c...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章
doi:10.1007/s00394-011-0189-0
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:Advanced glycation end products (AGEs) formed in food during high-heat cooking may induce overeating and inflammation. We investigated whether AGE contents in a single meal affect postprandial appetite and markers of inflammation, endothelial activation, and oxidative stress. METHODS:In total, 19 healthy overw...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-013-0574-y
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To provide a new and efficient at-the-toilet-bowl method of self-assessing urine concentration via urine color (Uc) to identify hypohydration. METHODS:A large athletic population (n = 189) delivered a urine sample, then chose a color panel that was displayed on the back wall of the lavatory stall. Selection wa...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02460-5
更新日期:2021-01-08 00:00:00
abstract:BACKGROUND:Depression is a very common disorder in elderly, especially in those institutionalized. Nutrition could play an important role in the onset and/or progression of depression, since the intake of carbohydrates with a high glycaemic index (GI) or diets with a high glycaemic load (GL) may increase the insulin-in...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-012-0412-7
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:To describe the patterns of ultra-processed foods (UPFs) consumption in the Netherlands; to test if exposure to the food environment is associated with UPFs consumption; and if this association differed across educational levels and neighbourhood urbanisation. METHODS:Cross-sectional study using 2015-data of 8...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02436-5
更新日期:2020-11-24 00:00:00
abstract:PURPOSE:Manifestation of allergic disease depends on genetic predisposition, diet and commensal microbiota. Genetic polymorphism of mothers determines their breast milk glycan composition. One major determinant is the fucosyltransferase 2 (FUT2, secretor gene) that was shown to be linked to commensal microbiota establi...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-016-1180-6
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:Chronic sugar-sweetened beverage (SSB) consumption is associated with obesity and type 2 diabetes mellitus (T2DM). Hyperglycaemia contributes to metabolic alterations observed in T2DM, such as reduced oxidative capacity and elevated glycolytic and lipogenic enzyme expressions in skeletal muscle tissue. We aimed...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章
doi:10.1007/s00394-012-0401-x
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:At the present time the recommended daily intake or allowance (RDA) and the safe upper level (UL) of intake of micronutrients are given as single values. The recommended daily intake is considered to cover the requirements of 97.5% of the population while the safe upper level is a value for the whole populat...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-007-0691-6
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Although research suggests that antioxidant supplementation can protect against exercise-induced muscle damage and oxidative stress, also delayed post-exercise muscle recovery and hindered adaptation to training were reported in the supplemented athletes. PURPOSE:The purpose of the study was to evaluate the...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-014-0757-1
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:While a relationship between alcohol and cardiovascular risk factors is well established, data suggest that the type of alcoholic beverage could modulate this relationship. AIM OF THE STUDY:To determine whether drinking patterns modulate the relationship between alcohol and cardiovascular risk factors. MET...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-005-0567-6
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:The use of soy products is common in young children with cow milk allergy (CMA). The aim was to examine prospectively the association between infantile consumption of soy-based formula, growth parameters and early pubertal signs, in comparison to cow milk-based formula. METHODS:A nested case-control study was ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-018-1668-3
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Vegetables and fruits are rich sources of a variety of nutrients, including vitamins (E and C), trace minerals, and dietary fibers, and many other classes of biologically active compounds such as carotenoids and polyphenols, which are often assumed to protect against degenerative pathologies such as cardiova...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-006-0594-y
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:Epidemiologic evidence on the potential effects of dietary acid load on frailty is lacking. This cross-sectional study examined the association between dietary acid load and frailty. METHODS:This study was based on self-reported data obtained from 2176 Japanese women aged 65-94 years. Dietary acid load was c...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-017-1449-4
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:To test the effect of three diets in their ability to sustain weight loss and improve type 2 diabetes (T2D) and cardiovascular disease (CVD) risk markers after 18-month intervention. METHODS:Following a ≥8 % weight loss, 131 healthy, overweight/obese (BMI ± SD 31.5 ± 2.6 kg/m2) men (n = 55) and women (n = 76) ...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-015-1116-6
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:To assess the effect of medium-chain fatty acid (MCFA)-rich mustard oil and polyunsaturated fatty acid (PUFA)-rich mustard oil on erythrocyte membrane composition and osmotic fragility in normal and hypercholesterolemic rats. METHOD:Membrane composition was analyzed using standard kits. Osmotic fragility was d...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-010-0150-7
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Dietary intakes are reflected in plasma by the presence of hundreds of exogenous metabolites and variations in endogenous metabolites. The exploration of diet-related plasma metabolic profiles could help to better understand the impact of overall diet on health. Our aim was to identify metabolomic signatures re...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02177-5
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Docosahexaenoic (C22:6) and arachidonic acid (C20:4) are long-chain polyunsaturated fatty acids (LC-PUFA), essential to fetal development, and preferentially transported by plasma phospholipids. OBJECTIVE:To characterize fetal and maternal plasma phospholipid changes during gestation, and to investigate whe...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-1036-5
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:To investigate the effect that wheat bran modified by autoclaving (MWB) had on reducing fat accumulation in hamsters fed a hypercholesterolemia- and obesity-inducing diet. METHODS:Male hamsters (n = 45) were randomized into 3 groups and fed a hypercholesterolemia- and obesity-inducing diet with or without 10% ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-013-0583-x
更新日期:2014-04-01 00:00:00
abstract:INTRODUCTION:Bioavailability is a critical feature in the assessment of the role of micronutrients in human health. Poorly bioavailable micronutrients like carotenoids may reach significant concentrations in the gastrointestinal tract where they may exert biological actions. PURPOSE:We evaluated a simple collection pr...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-015-0939-5
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:The study aimed to investigate the potential nephroprotective effects of vitamin D3 in metabolic syndrome (MetS) and the molecular basis of the underlying mechanisms of its action. METHODS:MetS was induced in adult male Wistar rats by adding fructose (10%) to every day drinking water and salt (3%) to the diet...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02249-6
更新日期:2020-04-22 00:00:00
abstract:PURPOSE:Osteoporosis is associated with both lower health-related quality of life and depression in older people. We examined the independent and combined effects of a multi-component exercise program and calcium-vitamin D3 fortified milk on health-related quality of life (HR-QoL) and depression in older men. METHODS:...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-019-01969-8
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Reactive oxygen radicals have been implicated in the pathophysiology of many neurologic disorders and brain dysfunctions. Kainic acid has been used as a model agent for the study of neurotoxicity of various excitatory amino acids, since it induces neuronal damage through excessive production of reactive oxyg...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-005-0565-8
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:Berries and mixed berry products exert acute effects on postprandial glycaemia and insulinemia, but very few berries have been studied, and primarily in normal weight subjects. Sea buckthorn and strawberry are compositionally widely different berries and may likely produce different responses. The effects of st...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-017-1550-8
更新日期:2018-12-01 00:00:00