A comparison of the transcriptome of Drosophila melanogaster in response to entomopathogenic fungus, ionizing radiation, starvation and cold shock.

abstract：BACKGROUND:Toxoplasmosis is caused by the apicomplexan parasite Toxoplasma gondii and can be acquired either congenitally or via the oral route. In the latter case, transmission is mediated by two distinct invasive stages, i.e., bradyzoites residing in tissue cysts or sporozoites contained in environmentally resistant ...

journal_title：BMC genomics

authors： Possenti A,Fratini F,Fantozzi L,Pozio E,Dubey JP,Ponzi M,Pizzi E,Spano F

更新日期：2013-03-15 00:00:00

abstract：BACKGROUND:Protein Disulfide Isomerases are thiol oxidoreductase chaperones from thioredoxin superfamily with crucial roles in endoplasmic reticulum proteostasis, implicated in many diseases. The family prototype PDIA1 is also involved in vascular redox cell signaling. PDIA1 is coded by the P4HB gene. While forced chan...

journal_title：BMC genomics

authors： Kajihara D,Hon CC,Abdullah AN,Wosniak J Jr,Moretti AIS,Poloni JF,Bonatto D,Hashimoto K,Carninci P,Laurindo FRM

更新日期：2020-11-04 00:00:00

abstract：BACKGROUND:The plastid acquisition by secondary endosymbiosis is a driving force for the algal evolution, and the comparative genomics was required to examine the genomic change of symbiont. Therefore, we established a pipeline of a de novo assembly of middle-sized genomes at a low cost and with high quality using long...

journal_title：BMC genomics

authors： Minei R,Hoshina R,Ogura A

更新日期：2018-09-24 00:00:00

abstract：BACKGROUND:Genomic approaches provide unique opportunities to study interactions of insects with their pathogens. We developed a cDNA microarray to analyze the gene transcription profile of the lepidopteran pest Spodoptera frugiperda in response to injection of the polydnavirus HdIV associated with the ichneumonid wasp...

journal_title：BMC genomics

authors： Barat-Houari M,Hilliou F,Jousset FX,Sofer L,Deleury E,Rocher J,Ravallec M,Galibert L,Delobel P,Feyereisen R,Fournier P,Volkoff AN

更新日期：2006-06-21 00:00:00

abstract：BACKGROUND:Anthocyanins are a group of flavonoid compounds. As a group of important secondary metabolites, they perform several key biological functions in plants. Anthocyanins also play beneficial health roles as potentially protective factors against cancer and heart disease. To elucidate the anthocyanin biosynthetic...

journal_title：BMC genomics

authors： Guo N,Cheng F,Wu J,Liu B,Zheng S,Liang J,Wang X

更新日期：2014-06-04 00:00:00

abstract：BACKGROUND:Ser/Thr/Tyr kinases (STYKs) commonly found in eukaryotes have been recently reported in many bacterial species. Recent studies elucidating their cellular functions have established their roles in bacterial growth and development. However functions of a large number of bacterial STYKs still remain elusive. Th...

journal_title：BMC genomics

authors： Krupa A,Srinivasan N

更新日期：2005-09-19 00:00:00

abstract：:As gene expression profile data from DNA microarrays accumulate rapidly, there is a natural need to compare data across labs and platforms. Comparisons of microarray data can be quite challenging due to data complexity and variability. Different labs may adopt different technology platforms. One may ask about the degr...

journal_title：BMC genomics

authors： Wang H,He X,Band M,Wilson C,Liu L

更新日期：2005-05-11 00:00:00

abstract：BACKGROUND:Arrhythmogenic cardiomyopathy (ACM) is a genetic autosomal disease characterized by abnormal cell-cell adhesion, cardiomyocyte death, progressive fibro-adipose replacement of the myocardium, arrhythmias and sudden death. Several different cell types contribute to the pathogenesis of ACM, including, as recent...

journal_title：BMC genomics

authors： Rainer J,Meraviglia V,Blankenburg H,Piubelli C,Pramstaller PP,Paolin A,Cogliati E,Pompilio G,Sommariva E,Domingues FS,Rossini A

更新日期：2018-06-25 00:00:00

abstract：BACKGROUND:Equine influenza is a major health problem of equines worldwide. The polymerase genes of influenza virus have key roles in virus replication, transcription, transmission between hosts and pathogenesis. Hence, the comprehensive genetic and codon usage bias of polymerase genes of equine influenza virus (EIV) w...

journal_title：BMC genomics

authors： Bera BC,Virmani N,Kumar N,Anand T,Pavulraj S,Rash A,Elton D,Rash N,Bhatia S,Sood R,Singh RK,Tripathi BN

更新日期：2017-08-23 00:00:00

abstract：BACKGROUND:The beta-defensin gene cluster (DEFB) at chromosome 8p23.1 is one of the most copy number (CN) variable regions of the human genome. Whereas individual DEFB CNs have been suggested as independent genetic risk factors for several diseases (e.g. psoriasis and Crohn's disease), the role of multisite sequence va...

journal_title：BMC genomics

authors： Taudien S,Groth M,Huse K,Petzold A,Szafranski K,Hampe J,Rosenstiel P,Schreiber S,Platzer M

更新日期：2010-04-19 00:00:00

abstract：BACKGROUND:Whilst being closely related to the model actinomycete Streptomyces coelicolor A3(2), S. lividans 66 differs from it in several significant and phenotypically observable ways, including antibiotic production. Previous comparative gene hybridization studies investigating such differences have used low-density...

journal_title：BMC genomics

authors： Lewis RA,Laing E,Allenby N,Bucca G,Brenner V,Harrison M,Kierzek AM,Smith CP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Accurate de novo genome assembly has become reality with the advancements in sequencing technology. With the ever-increasing number of de novo genome assembly tools, assessing the quality of assemblies has become of great importance in genome research. Although many quality metrics have been proposed and sof...

journal_title：BMC genomics

authors： Yavas G,Hong H,Xiao W

更新日期：2019-09-11 00:00:00

abstract：BACKGROUND:Teleost intestine is crucial for seawater acclimation by sensing osmolality of imbibed seawater and regulating drinking and water/ion absorption. Regulatory genes for transforming intestinal function have not been identified. A transcriptomic approach was used to search for such genes in the intestine of eur...

journal_title：BMC genomics

authors： Wong MK,Ozaki H,Suzuki Y,Iwasaki W,Takei Y

更新日期：2014-12-18 00:00:00

abstract：BACKGROUND:DNA methylation at promoters is largely correlated with inhibition of gene expression. However, the role of DNA methylation at enhancers is not fully understood, although a crosstalk with chromatin marks is expected. Actually, there exist contradictory reports about positive and negative correlations between...

journal_title：BMC genomics

authors： Sharifi-Zarchi A,Gerovska D,Adachi K,Totonchi M,Pezeshk H,Taft RJ,Schöler HR,Chitsaz H,Sadeghi M,Baharvand H,Araúzo-Bravo MJ

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:Cryptocaryon irritans is an obligate parasitic ciliate protozoan that can infect various commercially important mariculture fish species and cause high lethality and economic loss. Current methods of controlling this parasite with chemicals or antibiotics are widely considered to be environmentally harmful. ...

journal_title：BMC genomics

authors： Chen R,Mao Y,Wang J,Liu M,Qiao Y,Zheng L,Su Y,Ke Q,Zheng W

更新日期：2018-03-12 00:00:00

abstract：BACKGROUND:The orders Ascaridida, Oxyurida, and Spirurida represent major components of zooparasitic nematode diversity, including many species of veterinary and medical importance. Phylum-wide nematode phylogenetic hypotheses have mainly been based on nuclear rDNA sequences, but more recently complete mitochondrial (m...

journal_title：BMC genomics

authors： Park JK,Sultana T,Lee SH,Kang S,Kim HK,Min GS,Eom KS,Nadler SA

更新日期：2011-08-03 00:00:00

abstract：BACKGROUND:Next-Generation Sequencing has revolutionized our approach to ancient DNA (aDNA) research, by providing complete genomic sequences of ancient individuals and extinct species. However, the recovery of genetic material from long-dead organisms is still complicated by a number of issues, including post-mortem D...

journal_title：BMC genomics

authors： Schubert M,Ginolhac A,Lindgreen S,Thompson JF,Al-Rasheid KA,Willerslev E,Krogh A,Orlando L

更新日期：2012-05-10 00:00:00

abstract：BACKGROUND:Molecular characterization is important for efficient utilization of germplasm and development of improved varieties. In the present study, we investigated the genetic purity, relatedness and population structure of 265 maize inbred lines from the Ethiopian Institute of Agricultural Research (EIAR), the Inte...

journal_title：BMC genomics

authors： Ertiro BT,Semagn K,Das B,Olsen M,Labuschagne M,Worku M,Wegary D,Azmach G,Ogugo V,Keno T,Abebe B,Chibsa T,Menkir A

更新日期：2017-10-12 00:00:00

abstract：BACKGROUND:Fatty liver is a high incidence of perinatal disease in dairy cows caused by negative energy balance, which seriously threatens the postpartum health and milk production. It has been reported that lysine acetylation plays an important role in substance and energy metabolism. Predictably, most metabolic proce...

journal_title：BMC genomics

authors： Le-Tian Z,Cheng-Zhang H,Xuan Z,Zhang Q,Zhen-Gui Y,Qing-Qing W,Sheng-Xuan W,Zhong-Jin X,Ran-Ran L,Ting-Jun L,Zhong-Qu S,Zhong-Hua W,Ke-Rong S

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:Caixin and Zicaitai (Brassica rapa) belong to Southern and Central China respectively. Zicaitai contains high amount of anthocyanin in leaf and stalk resulting to the purple color. Stalk is the major edible part and stalk color is an economically important trait for the two vegetables. The aim of this study ...

journal_title：BMC genomics

authors： Li GH,Chen HC,Liu JL,Luo WL,Xie DS,Luo SB,Wu TQ,Akram W,Zhong YJ

更新日期：2019-05-07 00:00:00

abstract：BACKGROUND:Exiguobacterium antarcticum strain B7 is a Gram-positive psychrotrophic bacterial species isolated in Antarctica. Although this bacteria has been poorly studied, its genome has already been sequenced. Therefore, it is an appropriate model for the study of thermal adaptation. In the present study, we analyzed...

journal_title：BMC genomics

authors： Dall'Agnol HP,Baraúna RA,de Sá PH,Ramos RT,Nóbrega F,Nunes CI,das Graças DA,Carneiro AR,Santos DM,Pimenta AM,Carepo MS,Azevedo V,Pellizari VH,Schneider MP,Silva A

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:Most members of the serpin family of proteins are potent, irreversible inhibitors of specific serine or cysteine proteinases. Inhibitory serpins are distinguished from members of other families of proteinase inhibitors by their metastable structure and unique suicide-substrate mechanism. Animal serpins exert...

journal_title：BMC genomics

authors： Francis SE,Ersoy RA,Ahn JW,Atwell BJ,Roberts TH

更新日期：2012-09-04 00:00:00

abstract：BACKGROUND:Development of the soil amoeba Dictyostelium discoideum is triggered by starvation. When placed on a solid substrate, the starving solitary amoebae cease growth, communicate via extracellular cAMP, aggregate by tens of thousands and develop into multicellular organisms. Early phases of the developmental prog...

journal_title：BMC genomics

authors： Rosengarten RD,Santhanam B,Fuller D,Katoh-Kurasawa M,Loomis WF,Zupan B,Shaulsky G

更新日期：2015-04-13 00:00:00

abstract：BACKGROUND:Improvements in poultry production within the past 50 years have led to increased muscle yield and growth rate, which may be contributing to an increased rate and development of new muscle disorders in chickens. Previously reported muscle disorders and conditions are generally associated with poor meat quali...

journal_title：BMC genomics

authors： Mutryn MF,Brannick EM,Fu W,Lee WR,Abasht B

更新日期：2015-05-21 00:00:00

abstract：BACKGROUND:Soybean seed weight is not only a yield component, but also a critical trait for various soybean food products such as sprouts, edamame, soy nuts, natto and miso. Linkage analysis and genome-wide association study (GWAS) are two complementary and powerful tools to connect phenotypic differences to the underl...

journal_title：BMC genomics

authors： Yan L,Hofmann N,Li S,Ferreira ME,Song B,Jiang G,Ren S,Quigley C,Fickus E,Cregan P,Song Q

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:Protein phosphorylation by kinases plays crucial roles in various biological processes including signal transduction and tumorigenesis, thus a better understanding of protein phosphorylation events in cells is fundamental for studying protein functions and designing drugs to treat diseases caused by the malf...

journal_title：BMC genomics

authors： Ma H,Li G,Su Z

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:To understand gene expression networks leading to functional properties of the soybean seed, we have undertaken a detailed examination of soybean seed development during the stages of major accumulation of oils, proteins, and starches, as well as the desiccating and mature stages, using microarrays consistin...

journal_title：BMC genomics

authors： Jones SI,Gonzalez DO,Vodkin LO

更新日期：2010-02-24 00:00:00

abstract：BACKGROUND:The contribution of a gene to the fitness of a bacterium can be assayed by whether and to what degree the bacterium tolerates transposon insertions in that gene. We use this fact to compare the fitness of syntenic homologous genes among related Salmonella strains and thereby reveal differences not apparent a...

journal_title：BMC genomics

authors： Canals R,Xia XQ,Fronick C,Clifton SW,Ahmer BM,Andrews-Polymenis HL,Porwollik S,McClelland M

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Previous studies of individual genes have shown that in a self-enforcing way, dimethylation at histone 3 lysine 9 (dimethyl-H3K9) and DNA methylation cooperate to maintain a repressive mode of inactive genes. Less clear is whether this cooperation is generalized in mammalian genomes, such as mouse genome. He...

journal_title：BMC genomics

authors： Wu J,Wang SH,Potter D,Liu JC,Smith LT,Wu YZ,Huang TH,Plass C

更新日期：2007-05-24 00:00:00

abstract：BACKGROUND:Interactions among transcription factors (TFs) and histone modifications (HMs) play an important role in the precise regulation of gene expression. The context specificity of those interactions and further its dynamics in normal and disease remains largely unknown. Recent development in genomics technology e...

journal_title：BMC genomics

authors： Zhang L,Xue G,Liu J,Li Q,Wang Y

更新日期：2018-12-31 00:00:00