当前位置： SCI文献检索 > SPINE期刊下所有文献 > The Effect of Local Intraoperative Steroid Administration on the Rate of Postoperative Dysphagia Following ACDF: A Study of 245,754 Patients.

The Effect of Local Intraoperative Steroid Administration on the Rate of Postoperative Dysphagia Following ACDF: A Study of 245,754 Patients.

Abstract：

STUDY DESIGN:A retrospective database analysis. OBJECTIVE:The aim of this study is to compare rates of postoperative dysphagia, length of stay, infection, and wound complications following short and long anterior cervical discectomy and fusion (ACDF) in patients who received local intraoperative steroids and those who did not. SUMMARY OF BACKGROUND DATA:Only one prior small institutional study has investigated the application of local steroids at the time of ACDF to decrease postoperative dysphagia. METHODS:A large administrative database was utilized to compare rates of postoperative dysphagia, length of stay, and infectious complications within 90 days in patients who received local steroid following short (1-2 level) and long (3 or more level) ACDF and control groups who did not. Nonobtainable information within the database included type of steroid, application technique, outcome data, and incidence of miscoding and noncoding by physicians. Odds ratios (ORs), 95% confidence intervals (95% CIs) and P values were then calculated using SPSS. RESULTS:The incidence of dysphagia was significantly lower (9.0% vs. 14.6%, P = 0.005) in patients who received local steroid in the long ACDF group (n = 322) than a control group who did not (n = 45,432). This was not observed (P = 0.198) in the short ACDF group who received steroid (n = 1770) compared with a control group who did not (n = 198,230). The mean difference in length of stay was 1 day less for patients who received local steroid in both the short and long ACDF groups (P < 0.0001). The combined rate of postoperative infection and wound complications was not significantly different between steroid and control groups (P = 0.717). CONCLUSION:This analysis of a large administrative database suggests that local intraoperative steroid is associated with a significantly reduced rate of postoperative dysphagia after long ACDF and reduced average length of stay following both long and short ACDF without any increase in the rate of postoperative infection or wound complication. LEVEL OF EVIDENCE:3.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Cancienne JM,Werner BC,Loeb AE,Yang SS,Hassanzadeh H,Singla A,Shen FH,Shimer AL

doi

10.1097/BRS.0000000000001407

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

1084-1088

issue

eissn

0362-2436

issn

1528-1159

pii

00007632-201607010-00008

journal_volume

pub_type

杂志文章

在线工具

The Effect of Local Intraoperative Steroid Administration on the Rate of Postoperative Dysphagia Following ACDF: A Study of 245,754 Patients.