Efflux pump induction by quaternary ammonium compounds and fluoroquinolone resistance in bacteria.

abstract：:Some intracellular/membranous factors exert intrinsic immunity against viral pathogens. Most recently, SAMHD1 has been shown to be one of these factors. SAMHD1 is a nucleus-localized protein, and mutations in the gene are associated with Aicardi-Goutières syndrome. As a triphosphohydrolase, it depletes the intracellul...

journal_title：Future microbiology

authors： Chen Z,Zhang L,Ying S

更新日期：2012-09-01 00:00:00

abstract：:Aim: The purpose of this study was to evaluate the antifungal activity of midazolam, alone and in association with azoles, against isolates of clinical Candida spp. in planktonic and biofilm form. Materials & methods: The antifungal activity was observed using the broth microdilution technique. Flow cytometry tests we...

journal_title：Future microbiology

authors： Holanda MA,da Silva CR,de A Neto JB,do Av Sá LG,do Nascimento FB,Barroso DD,da Silva LJ,Cândido TM,Leitão AC,Barbosa AD,de Moraes MO,Cc B,Júnior HVN

更新日期：2021-01-01 00:00:00

abstract：:A number of viruses in the family Arenaviridae cause severe illness in humans. Lassa virus in West Africa and a number of agents in South America produce hemorrhagic fever in persons exposed to aerosolized excretions of the pathogens' rodent hosts. Because arenaviruses are not transmitted by arthropods, and person-to-...

journal_title：Future microbiology

authors： Gowen BB,Bray M

更新日期：2011-12-01 00:00:00

abstract：:Genotyping is used to track specific isolates of Mycobacterium tuberculosis in a community. It has been successfully used in epidemiologic research (termed 'molecular epidemiology') to study the transmission dynamics of TB. In this article, we review the genetic markers used in molecular epidemiologic studies includin...

journal_title：Future microbiology

authors： Kato-Maeda M,Metcalfe JZ,Flores L

更新日期：2011-02-01 00:00:00

abstract：AIM:The primary objective of this study was to evaluate correlations among mortality, intensive care unit (ICU) length of stay and airway microbiotas in septic patients. MATERIALS & METHODS:A deep-sequencing analysis of the 16S rRNA gene V4 region was performed. RESULTS:The nasal microbiota in septic patients was dom...

journal_title：Future microbiology

authors： Tan XL,Liu HY,Long J,Jiang Z,Luo Y,Zhao X,Cai S,Zhong X,Cen Z,Su J,Zhou H

更新日期：2019-03-01 00:00:00

abstract：:Chronic hepatitis B virus infection is a global health concern as it affects over 240 million people worldwide and an estimated 686,000 people die annually as a result of complications of the disease. With the development of newer antiviral drugs, viral suppression of HBV is achievable, however elimination of HBV from...

journal_title：Future microbiology

authors： Ward H,Tang L,Poonia B,Kottilil S

更新日期：2016-12-01 00:00:00

abstract：:The human periodontium health is commonly compromised by chronic inflammatory conditions and has become a major public health concern. Dental plaque, the precursor of periodontal disease, is a complex biofilm consisting mainly of bacteria, but also archaea, protozoa, fungi and viruses. Viruses that specifically infect...

journal_title：Future microbiology

authors： Pinto G,Silva MD,Peddey M,Sillankorva S,Azeredo J

更新日期：2016-10-01 00:00:00

abstract：:Traditionally, glycoproteins have been considered the exclusive property of eukaryotes and archaea, but it is now evident that glycoproteins are found in all domains of life. In recent years N-linked glycosylation among some epsilon-proteobacteria has emerged as a new and exciting research area and represents a useful...

journal_title：Future microbiology

authors： Langdon RH,Cuccui J,Wren BW

更新日期：2009-05-01 00:00:00

abstract：:Aim: To determine the group of compounds from Chrysopogon zizaniodes root essential oil that have antimicrobial activity. Materials & methods: Thin-layer chromatography coupled to direct bioautography was used to determinate the fraction(s) having antimicrobial activity against methicillin-resistant Staphylococcus aur...

journal_title：Future microbiology

authors： Ramírez-Rueda RY,Marinho J,Salvador MJ

更新日期：2019-09-01 00:00:00

abstract：:The term 'neglected tropical diseases' predominantly refers to single-entity, mostly parasitic diseases. However, a considerable morbidity and mortality burden is carried by patients infected with Gram-positive cocci and Gram-negative bacilli that are prevalent all over the world, yet have impact in tropical and devel...

journal_title：Future microbiology

authors： Herrmann M,Abdullah S,Alabi A,Alonso P,Friedrich AW,Fuhr G,Germann A,Kern WV,Kremsner PG,Mandomando I,Mellmann AC,Pluschke G,Rieg S,Ruffing U,Schaumburg F,Tanner M,Peters G,von Briesen H,von Eiff C,von Müller L,Gr

更新日期：2013-01-01 00:00:00

abstract：:Helicobacter pylori (H. pylori) has an essential role in the pathogenesis of gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma and gastric cancer. The severity of the host inflammatory responses against the bacteria have been straightly associated with a special bacterial virulence factor, th...

journal_title：Future microbiology

authors： Yuan XY,Wang Y,Wang MY

更新日期：2018-07-01 00:00:00

abstract：:Mycobacterium tuberculosis is included among a select group of bacteria possessing the capacity for de novo biosynthesis of vitamin B12, the largest and most complex natural organometallic cofactor. The bacillus is also able to scavenge B12 and related corrinoids utilizing an ATP-binding cassette-type protein that is ...

journal_title：Future microbiology

authors： Gopinath K,Moosa A,Mizrahi V,Warner DF

更新日期：2013-11-01 00:00:00

abstract：:This paper analyzes the most recent reports regarding the direct and indirect effects of the 13-valent pneumococcal conjugate vaccine (PCV13) when administered to infants and young children. PCV13 extends the protective effects reported for the 7-valent pneumococcal conjugate vaccine (PCV7). A further reduction in the...

journal_title：Future microbiology

authors： Esposito S,Principi N,ESCMID Vaccine Study Group.

更新日期：2015-01-01 00:00:00

abstract：:Temporal and spatial fluctuations in the genotype distribution of human rotaviruses are continuously observed in surveillance studies. New genotypes, such as G9 and G12, have emerged and spread worldwide in a very short time span. In addition, reassortment events have the potential to contribute substantially to genet...

journal_title：Future microbiology

authors： Matthijnssens J,Bilcke J,Ciarlet M,Martella V,Bányai K,Rahman M,Zeller M,Beutels P,Van Damme P,Van Ranst M

更新日期：2009-12-01 00:00:00

abstract：:Group A Streptococcus (GAS) is a leading human bacterial pathogen with diverse clinical manifestations. Macrophages constitute a critical first line of host defense against GAS infection, using numerous surface and intracellular receptors such as Toll-like receptors and inflammasomes for pathogen recognition and activ...

journal_title：Future microbiology

authors： Valderrama JA,Nizet V

更新日期：2018-01-01 00:00:00

abstract：:During coevolution with their hosts, bacteria have developed functions that allow them to interfere with the mechanisms controlling the proliferation of eukaryotic cells. Cycle inhibiting factor (Cif) is one of these cyclomodulins, the family of bacterial effectors that interfere with the host cell cycle. Acquired ear...

journal_title：Future microbiology

authors： Samba-Louaka A,Taieb F,Nougayrède JP,Oswald E

更新日期：2009-09-01 00:00:00

abstract：:Breastfeeding is a major determinant of human health. Breast milk is not sterile and ecological large-scale sequencing methods have revealed an unsuspected microbial diversity that plays an important role. However, microbiological analysis at the species level has been neglected while it is a prerequisite before under...

journal_title：Future microbiology

authors： Togo A,Dufour JC,Lagier JC,Dubourg G,Raoult D,Million M

更新日期：2019-05-01 00:00:00

abstract：:The recent years have witnessed significant progress in the development of new drug candidates for the treatment of TB. While many of these are now in clinical trials, continued research is needed in order to sustain the drug discovery pipeline and meet the increasing needs of TB patients. These include shortening tre...

journal_title：Future microbiology

authors： Sala C,Hartkoorn RC

更新日期：2011-06-01 00:00:00

abstract：AIM:Diagnosis of pleural TB poses serious challenges due to paucibacillary nature of specimens and there is an urgent need to devise a reliable diagnostic test. METHODS:We compared GeneXpert Mycobacterium tuberculosis/rifampin assay and the multiplex PCR (M-PCR) targeting mpb64 (Rv1980c) and IS6110 in pleural fluids (...

journal_title：Future microbiology

authors： Sharma S,Dahiya B,Sreenivas V,Singh N,Raj A,Sheoran A,Yadav A,Gupta KB,Mehta PK

更新日期：2018-03-01 00:00:00

abstract：:Background: Sporotrichosis occurs through contact with contaminated soil and plant. However, the incidence of sporotrichosis as a zoonotic epidemic has increased, particularly in Rio de Janeiro. Aim: In this work, we decided to evaluate some T-cell phenotypes involved in the immune response. Materials & methods: We us...

journal_title：Future microbiology

authors： Corrêa-Moreira D,De Luca PM,Romeo O,C Menezes R,Paes RA,Oliveira RZ,de Moraes AM,de L Neto RG,Moraes Borba C,E de Oliveira MM

更新日期：2020-09-01 00:00:00

abstract：:Salmonella enterica is an invasive, facultative intracellular gastrointestinal pathogen causing human diseases such as gastroenteritis and typhoid fever. Virulence-attenuated strains of this pathogen have interesting capacities for the generation of live vaccines. Attenuated live typhoidal and nontyphoidal Salmonella ...

journal_title：Future microbiology

authors： Hegazy WA,Hensel M

更新日期：2012-01-01 00:00:00

abstract：:Retapamulin is a semisynthetic pleuromutilin compound with in vitroactivity against Gram-positive bacteria, no cross-resistance to other classes of antimicrobial agents in current use and a low potential for development of resistance. A 1% ointment formulation has been developed for clinical use, and a placebo-control...

journal_title：Future microbiology

authors： Jacobs MR

更新日期：2007-12-01 00:00:00

abstract：AIMS:To investigate the antitumor effects of probiotics Clostridium butyricum and Bacillus subtilis on colorectal cancer (CRC) progression. MATERIALS & METHODS:The effects of C. butyricum and B. subtilis on CRC cells were studied. Male C57BL/6 mice with 1,2-dimethylhydrazine dihydrochloride (DMH)-induced CRC were inte...

journal_title：Future microbiology

authors： Chen ZF,Ai LY,Wang JL,Ren LL,Yu YN,Xu J,Chen HY,Yu J,Li M,Qin WX,Ma X,Shen N,Chen YX,Hong J,Fang JY

更新日期：2015-01-01 00:00:00

abstract：:Aim: Multidrug-resistant Staphylococcus aureus isolates have become a serious concern in clinical microbiology. Antisense strategy, which specifically targets essential genes, could be helpful. Materials & methods:S. aureus cultures were treated with peptide conjugate-peptide nucleic acid (PPNA) specific for the gyrA ...

journal_title：Future microbiology

authors： Tavakoli M,Hashemi A,Vaezjalali M,Mohammadzadeh M,Goudarzi H

更新日期：2019-09-01 00:00:00

abstract：:Among the 33 confirmed Bartonella species to date, more than half are hosted by rodent species, and at least five of them have been involved in human illness causing diverse symptoms including fever, myocarditis, endocarditis, lymphadenitis and hepatitis. In almost all countries, wild rodents are infected by extremely...

journal_title：Future microbiology

authors： Buffet JP,Kosoy M,Vayssier-Taussat M

更新日期：2013-09-01 00:00:00

abstract：:In this exclusive interview, Simon Gaisford discusses his current research into gut dysbiosis and its possible relevance to disease states, as well as the efficacy of probiotic supplementation and its possible use as treatment. This interview was conducted by Ellen Colvin, Commissioning Editor of Future Microbiology. ...

journal_title：Future microbiology

authors： Gaisford S

更新日期：2019-03-01 00:00:00

abstract：:Chlamydial infections cause a wide range of acute and chronic diseases. Chlamydia trachomatis is the most common sexually transmitted bacterium while Chlamydia pneumoniae causes infections of the upper and lower respiratory tract. Chlamydia are obligate, intracellular bacteria with a biphasic developmental cycle that ...

journal_title：Future microbiology

authors： Käding N,Szaszák M,Rupp J

更新日期：2014-01-01 00:00:00

abstract：:Carbapenem-resistant Acinetobacter baumannii (CRAB) is endemic in Greece. CRAB initially emerged in 2000 and since then, carbapenemases still have a crucial role in CRAB appearance, except for a few cases resulting from efflux pump or outer-membrane protein mechanisms. OXA-type carbapenemases present the highest preva...

journal_title：Future microbiology

authors： Karampatakis T,Antachopoulos C,Tsakris A,Roilides E

更新日期：2017-07-01 00:00:00

abstract：:Amoebiasis is a serious infectious disease that is caused by the unicellular parasite, Entamoeba histolytica. This parasite is mainly found in developing countries, and are named owing to its ability to destroy tissues. The molecular mechanisms that regulate the virulence of this parasite are not well understood. In r...

journal_title：Future microbiology

authors： Tovy A,Ankri S

更新日期：2010-12-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate epidemiology and susceptibility patterns of nosocomial Gram-positive infections in a referral teaching hospital. METHODS:Over a 1 year period, Gram-positive microorganisms isolated from specimens of hospitalized patients with documented nosocomial infection underwent antimicro...

journal_title：Future microbiology

authors： Soltani R,Khalili H,Abdollahi A,Rasoolinejad M,Dashti-Khavidaki S

更新日期：2012-07-01 00:00:00