Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells.

abstract：BACKGROUND:With their Pan-American distribution, long-nosed armadillos (genus Dasypus) constitute an understudied model for Neotropical biogeography. This genus currently comprises seven recognized species, the nine-banded armadillo (D. novemcinctus) having the widest distribution ranging from Northern Argentina to the...

journal_title：PeerJ

authors： Billet G,Hautier L,de Thoisy B,Delsuc F

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:Self-contained tests estimate and test the association between a phenotype and mean expression level in a gene set defined a priori. Many self-contained gene set analysis methods have been developed but the performance of these methods for phenotypes that are continuous rather than discrete and with multiple...

journal_title：PeerJ

authors： Walker JA

更新日期：2016-10-11 00:00:00

abstract：Background:Panulirus argus is an ecologically relevant species in shallow water hard-bottom environments and coral reefs and target of the most lucrative fishery in the greater Caribbean region. Methods:This study reports, for the first time, the genome size and nuclear repetitive elements, including the 45S ribosomal...

journal_title：PeerJ

authors： Baeza JA

更新日期：2020-12-17 00:00:00

abstract：:In the Balearic Islands, different trammel net designs have been adopted to promote fisheries sustainability and reduce discards. Here, we compare the catch performance of three trammel net designs targeting the spiny lobster Palinurus elephas in terms of biomass, species composition and revenue from commercial catche...

journal_title：PeerJ

authors： Catanese G,Hinz H,Gil MDM,Palmer M,Breen M,Mira A,Pastor E,Grau A,Campos-Candela A,Koleva E,Grau AM,Morales-Nin B

更新日期：2018-05-17 00:00:00

abstract：:The selection and validation of proper distinguishing characters are of crucial importance in taxonomic revisions. The modern classifications of orchids utilize the molecular tools, but still the selection and identification of the material used in these studies is for the most part related to general species morpholo...

journal_title：PeerJ

authors： Jakubska-Busse A,Żołubak E,Łobas Z,Gola EM

更新日期：2017-07-21 00:00:00

abstract：Background:Cholera, an acute enteric infection, is a serious health challenge in both the underdeveloped and the developing world. It is caused by Vibrio cholerae after ingestion of fecal contaminated food or water. Cholera outbreaks have recently been observed in regions facing natural calamities (i.e., earthquake in ...

journal_title：PeerJ

authors： Rashid MI,Rehman S,Ali A,Andleeb S

更新日期：2019-06-19 00:00:00

abstract：:Sex differences in some preferences and motivations are well established, but it is unclear whether they persist in selective sub-populations, such as expert financial decision makers, top scientists, or elite athletes. We addressed this issue by studying competitiveness in 1,147 varsity intercollegiate distance runne...

journal_title：PeerJ

authors： Deaner RO,Lowen A,Rogers W,Saksa E

更新日期：2015-04-21 00:00:00

abstract：:We documented significantly increasing trends in atmospheric loading of ammonium (NH4) and nitrate/nitrite (NO2/3) and decreasing trends in total phosphorus (P) and sulfate (SO4) to Flathead Lake, Montana, from 1985 to 2004. Atmospheric loading of NO2/3 and NH4 increased by 48 and 198% and total P and SO4 decreased by...

journal_title：PeerJ

authors： Ellis BK,Craft JA,Stanford JA

更新日期：2015-03-19 00:00:00

abstract：Background:The independent effects of hypohydration and hyperthermia on cognition and mood is unclear since the two stresses often confound each other. Further, it is unknown if obese individuals have the same impairments during hyperthermia and hypohydration that is often observed in non-obese individuals. Methods:Th...

journal_title：PeerJ

authors： Caldwell AR,Burchfield J,Moyen NE,Tucker MA,Butts CL,Elbin RJ,Ganio MS

更新日期：2018-08-16 00:00:00

abstract：:Resistance strategies of clonal organs, and parent and offspring shoots of Phragmites australis (common reed) to heavy metal pollution in soils are not well known. To clarify the tolerance or resistance strategies in reeds, we conducted a pot experiment with five levels of Pb concentration (0∼4,500 mg kg-1) in flood a...

journal_title：PeerJ

authors： Zhang N,Zhang J,Li Z,Chen J,Zhang Z,Mu C

更新日期：2018-01-03 00:00:00

abstract：:The genus Pseudostegana (Okada, 1978) currently contains thirty-nine described species. A number of Pseudostegana were collected from the fieldwork in southwestern China from 2010 to 2017. Eleven new species were discovered and are described from southwestern China: Pseudostegana alpina Zhang & Chen, sp. nov.; Pseudos...

journal_title：PeerJ

authors： Lu J,Zhang Y,Chen H

更新日期：2018-09-05 00:00:00

abstract：:The cryptic species that make up the Euwallacea fornicatus species complex can be readily distinguished via their DNA sequences. Until recently, it was believed that the Hawaiian Islands had been invaded by only one of these cryptic species, E. perbrevis (tea shot hole borer; TSHB). However, following the 2016 deposit...

journal_title：PeerJ

authors： Rugman-Jones PF,Au M,Ebrahimi V,Eskalen A,Gillett CPDT,Honsberger D,Husein D,Wright MG,Yousuf F,Stouthamer R

更新日期：2020-09-17 00:00:00

abstract：:Four species of true crocodile (genus Crocodylus) have been described from the Americas. Three of these crocodile species exhibit non-overlapping distributions-Crocodylus intermedius in South America, C. moreletii along the Caribbean coast of Mesoamerica, and C. rhombifer confined to Cuba. The fourth, C. acutus, is na...

journal_title：PeerJ

authors： Milián-García Y,Russello MA,Castellanos-Labarcena J,Cichon M,Kumar V,Espinosa G,Rossi N,Mazzotti F,Hekkala E,Amato G,Janke A

更新日期：2018-11-12 00:00:00

abstract：:Coarse-grained (CG) models have been successful in simulating the chemical properties of lipid bilayers, but accurate treatment of membrane proteins and lipid-protein molecular interactions remains a challenge. The CgProt force field, original developed with the multiscale coarse graining method, is assessed by compar...

journal_title：PeerJ

authors： Hills RD Jr

更新日期：2018-01-10 00:00:00

abstract：:"Higher" termites have been able to colonize all tropical and subtropical regions because of their ability to digest lignocellulose with the aid of their prokaryotic gut microbiota. Over the last decade, numerous studies based on 16S rRNA gene amplicon libraries have largely described both the taxonomy and structure o...

journal_title：PeerJ

authors： Hervé V,Liu P,Dietrich C,Sillam-Dussès D,Stiblik P,Šobotník J,Brune A

更新日期：2020-02-13 00:00:00

abstract：BACKGROUND:Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment, since it has been isolated from water, soil or dust. In rec...

journal_title：PeerJ

authors： Sanchini A,Dematheis F,Semmler T,Lewin A

更新日期：2017-01-03 00:00:00

abstract：:Herbivory and nutrient enrichment are drivers of benthic dynamics of coral reef macroalgae; however, their impact may vary seasonally. In this study we evaluated the effects of herbivore pressure, nutrient availability and potential propagule supply on seasonal recruitment and succession of macroalgal communities on a...

journal_title：PeerJ

authors： Duran A,Collado-Vides L,Burkepile DE

更新日期：2016-11-02 00:00:00

abstract：:Although liver cirrhosis and hepatocellular carcinoma are major consequences of hepatitis C (HCV), there has been an increasing number of studies examining extrahepatic manifestations, especially those caused by systemic chronic inflammation and metabolic complications that might predispose HCV patients to atheroscler...

journal_title：PeerJ

authors： Pavicic Ivelja M,Dolic K,Tandara L,Perkovic N,Mestrovic A,Ivic I

更新日期：2021-01-14 00:00:00

abstract：:China has experienced intensive urbanization over the past decades. However, it is still unclear about the influence of urbanization on urban thermal comfort and how the effect varies with climate condition. Based on long-term daily meteorological data from 1990 to 2015 in four Chinese cities undergoing rapid urbaniza...

journal_title：PeerJ

authors： Fu Y,Ren Z,Yu Q,He X,Xiao L,Wang Q,Liu C

更新日期：2019-11-11 00:00:00

abstract：Background:Herpesviral hematopoietic necrosis disease, caused by cyprinid herpesvirus-2 (CyHV-2), is responsible for massive mortalities in the aquaculture of goldfish, Carassius auratus. Permissive cell lines for the isolation and propagation of CyHV-2 have been established from various goldfish tissues by sacrificing...

journal_title：PeerJ

authors： Dharmaratnam A,Kumar R,Valaparambil BS,Sood N,Pradhan PK,Das S,Swaminathan TR

更新日期：2020-07-14 00:00:00

abstract：Background:The ongoing change in climate is predicted to exert unprecedented effects on Earth's biodiversity at all levels of organization. Biological conservation is important to prevent biodiversity loss, especially for species facing a high risk of extinction. Understanding the past responses of species to climate c...

journal_title：PeerJ

authors： Bai Y,Wei X,Li X

更新日期：2018-01-16 00:00:00

abstract：OBJECTIVE:The aim of our study was to identify barriers and enablers to implementation of the Xpert MTB/RIF test within Mongolia's National Tuberculosis Program. METHODS:Twenty-foursemi-structured interviews were conducted between June and September 2015 with laboratory staff and tuberculosis physicians in Mongolia's ...

journal_title：PeerJ

authors： Rendell NL,Bekhbat S,Ganbaatar G,Dorjravdan M,Pai M,Dobler CC

更新日期：2017-07-14 00:00:00

abstract：:A strong argument can be made that the European Union has the most rigorous regulatory system for pesticides in the world, and that modern pesticide use poses fewer environmental threats than older regimes. Nevertheless, the impacts of pesticides on bees and other non-target organisms are much debated in Europe as els...

journal_title：PeerJ

authors： Goulson D,Thompson J,Croombs A

更新日期：2018-07-19 00:00:00

abstract：:Monkeypox (MPX) is a zoonotic disease similar to smallpox. Its fatality rate is about 11% and it is endemic to the Central and West African countries. In this paper, we analyze a compartmental model of MPX dynamics. Our goal is to see whether MPX can be controlled and eradicated by voluntary vaccinations. We show that...

journal_title：PeerJ

authors： Bankuru SV,Kossol S,Hou W,Mahmoudi P,Rychtář J,Taylor D

更新日期：2020-06-22 00:00:00

abstract：Background:The highest rate of cancer-related deaths worldwide is from lung adenocarcinoma (LUAD) annually. Metabolism was associated with tumorigenesis and cancer development. Metabolic-related genes may be important biomarkers and metabolic therapeutic targets for LUAD. Materials and Methods:In this study, the glean...

journal_title：PeerJ

authors： Zhao Z,He B,Cai Q,Zhang P,Peng X,Zhang Y,Xie H,Wang X

更新日期：2020-09-24 00:00:00

abstract：:Marine sponges host complex microbial consortia that vary in their abundance, diversity and stability amongst host species. While our understanding of sponge-microbe interactions has dramatically increased over the past decade, little is known about how sponges and their microbial symbionts interact with viruses, the ...

journal_title：PeerJ

authors： Pascelli C,Laffy PW,Kupresanin M,Ravasi T,Webster NS

更新日期：2018-10-17 00:00:00

abstract：:Due to varietal differences, diminutive size, and similar morphological characters, it is difficult to classify and identify Liriomyza spp., a genus comprised of economically-important, highly-polyphagous insect pests. In this study, we reconfirmed the morphological characteristics of three closely-related invasive le...

journal_title：PeerJ

authors： Chang YW,Chen JY,Zheng SZ,Gao Y,Chen Y,Deng Y,Du YZ

更新日期：2020-10-30 00:00:00

abstract：:Background. Little is known about the characteristics of internet distractions that students may engage in during lecture. The objective of this pilot study is to identify some of the internet-based distractions students engage in during in-person lectures. The findings will help identify what activities most commonly...

journal_title：PeerJ

authors： Nalliah RP,Allareddy V

更新日期：2014-09-16 00:00:00

abstract：Background:The body of literature regarding the associations between physical activity and psychological problems lacks consensus. Moreover, the role of gender has been scarcely investigated. The present study sought to fill the gap in the data by examining the associations, if any, between moderate-to-vigorous physica...

journal_title：PeerJ

authors： Liu M,Zhang J,Kamper-DeMarco KE,Hu E,Yao S

更新日期：2020-03-25 00:00:00

abstract：Background:Stoichiometric relations drive powerful constraints in several fundamental ecosystem processes. However, limited studies have been conducted on the ecological stoichiometry of plants after the change of community composition induced by Stellera chamaejasme removal in alpine grassland in the Qinghai-Tibetan P...

journal_title：PeerJ

authors： Song M,Wang Y,Bao G,Wang H,Yin Y,Li X,Zhang C

更新日期：2020-06-23 00:00:00