Kinetic analysis of excitation-contraction coupling.

abstract：:Transformation of 3T3 cells by SV40 virus changes the properties of the transplasma membrane electron transport activity which can be assayed by reduction of external ferric salts. After 42 h of culture and before the growth rate is maximum, the transformed cells have a much slower rate of ferric reduction. The change...

journal_title：Journal of bioenergetics and biomembranes

authors： Löw H,Crane FL,Grebing C,Isaksson M,Lindgren A,Sun IL

更新日期：1991-12-01 00:00:00

abstract：:A sodium-dependent phosphate transporter (type II Na/Pi-cotransporter) was isolated which is expressed in apical membranes of proximal tubules and exhibits transport characteristics similar as described for renal reabsorption of phosphate. Type II associated Na/Pi-cotransport is electrogenic and results obtained by el...

journal_title：Journal of bioenergetics and biomembranes

authors： Biber J,Murer H,Forster I

更新日期：1998-04-01 00:00:00

abstract：:Hydroxyl radical (HO•) production in photosystem II (PSII) was studied by electron paramagnetic resonance (EPR) spin-trapping technique. It is demonstrated here that the exposure of PSII membranes to heat stress (40 °C) results in HO• formation, as monitored by the formation of EMPO-OH adduct EPR signal. The presence ...

journal_title：Journal of bioenergetics and biomembranes

authors： Yadav DK,Pospíšil P

更新日期：2012-06-01 00:00:00

abstract：:The past 5 years has witnessed an advance in our understanding of alpha1G (Cav3.1), alpha1H (Cav3.2), and alpha11 (Car3.3), the pore-forming subunits of T-type or low-voltage-activated calcium channels (LVAs). LVAs differ in their localization and molecular, biophysical, and biochemical properties, but all conduct a t...

journal_title：Journal of bioenergetics and biomembranes

authors： Yunker AM,McEnery MW

更新日期：2003-12-01 00:00:00

abstract：:Two kinds of ATP binding sites were found on the ATPase molecule in deoxycholic acid-treated sarcoplasmic reticulum. One was the catalytic site (1 mol/mol active site) and its affinity was high. Upon addition of Ca2+, all the ATP bound to the catalytic site disappeared at 75 mM KCl, while a significant amount of ATP r...

journal_title：Journal of bioenergetics and biomembranes

authors： Nakamura Y,Tonomura Y

更新日期：1982-12-01 00:00:00

abstract：:Caloric restriction (CR) is widely known to increase life span and resistance to different types of injuries in several organisms. We have previously shown that mitochondria from livers or brains of CR animals exhibit higher calcium uptake rates and lower sensitivity to calcium-induced mitochondrial permeability trans...

journal_title：Journal of bioenergetics and biomembranes

authors： Serna JDC,Caldeira da Silva CC,Kowaltowski AJ

更新日期：2020-08-01 00:00:00

abstract：:A study of NADH ferricyanide reductase activity in oriented vesicles or open ghosts of human and porcine erythrocytes shows that the dehydrogenase activity can have three types of orientation in the membrane. There is activity which responds only to acceptors and NADH exclusively on the inside face, or exclusively on ...

journal_title：Journal of bioenergetics and biomembranes

authors： Crane FL,Crane HE,Sun IL,MacKellar WC,Grebing C,Löw H

更新日期：1982-12-01 00:00:00

abstract：:The topic of human adult neural plasticity and neurogenesis is of great interest for medical and scientific community, but it is also largely debated. In the last years, an increasing interest has been paid to the olfactory system, and particularly to the plasticity of the olfactory bulb (OB). While the molecular/cell...

journal_title：Journal of bioenergetics and biomembranes

authors： Huart C,Rombaux P,Hummel T

更新日期：2019-02-01 00:00:00

abstract：:The adenylate kinase (AK) isoforms network plays an important role in the intracellular energy transfer processes, the maintenance of energy homeostasis, and it is a major player in AMP metabolic signaling circuits in some highly-differentiated cells. For this purpose, a rapid and sensitive method was developed that e...

journal_title：Journal of bioenergetics and biomembranes

authors： Klepinin A,Ounpuu L,Guzun R,Chekulayev V,Timohhina N,Tepp K,Shevchuk I,Schlattner U,Kaambre T

更新日期：2016-10-01 00:00:00

abstract：:The respiratory chain of marine and moderately halophilic bacteria requires Na+ for maximum activity, and the site of Na(+)-dependent activation is located in the NADH-quinone reductase segment. The Na(+)-dependent NADH-quinone reductase purified from marine bacterium Vibrio alginolyticus is composed of three subunits...

journal_title：Journal of bioenergetics and biomembranes

authors： Unemoto T,Hayashi M

更新日期：1993-08-01 00:00:00

abstract：:Eukaryotic porins or VDACs are a class of transmembrane proteins mainly localized in the outer mitochondrial membrane, whose function is to allow the diffusion of metabolites between the cytosol and the mitochondrion. In Drosophila melanogaster, as in other organisms, a small family of genes encoding porins has been d...

journal_title：Journal of bioenergetics and biomembranes

authors： Specchia V,Guarino F,Messina A,Bozzetti MP,De Pinto V

更新日期：2008-06-01 00:00:00

abstract：:The induction of millisecond delayed fluorescence mediated by PS I-dependent proton pumping has been used as an indicator of the time course with which those protons equilibrate with sites on the oxygen-evolving enzyme complex (Bowes, J. M., and Crofts, A. R. (1978). Z. Naturforsch. 33C, 271-275). We found that the in...

journal_title：Journal of bioenergetics and biomembranes

authors： Theg SM,Belanger KM,Dilley RA

更新日期：1987-02-01 00:00:00

abstract：:The presence of additional subunits in cytochrome oxidase distinguish the multicellular eukaryotic enzyme from that of a simple unicellular bacterial enzyme. The number of these additional subunits increases with increasing evolutionary stage of the organism. Subunits I-III of the eukaryotic enzyme are related to the ...

journal_title：Journal of bioenergetics and biomembranes

authors： Kadenbach B,Stroh A,Hüther FJ,Reimann A,Steverding D

更新日期：1991-04-01 00:00:00

abstract：:Plasma membrane vesicles of HeLa cells are characterized by a drug-responsive oxidation of NADH. The NADH oxidation takes place in an argon or nitrogen atmosphere and in samples purged of oxygen. Direct assay of protein thiols by reaction with 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB; Ellman's reagent), suggests tha...

journal_title：Journal of bioenergetics and biomembranes

authors： Morré DJ,Chueh PJ,Lawler J,Morré DM

更新日期：1998-10-01 00:00:00

abstract：:Retinoic acid inhibits the reduction of diferric transferrin through the transplasma membrane electron transport system on fetal rat liver cells infected with a temperature-sensitive SV40 virus when the cells are in the nontransformed state cultured at 40 degrees C. When the cells are in the transformed state (grown a...

journal_title：Journal of bioenergetics and biomembranes

authors： Sun IL,Toole-Simms W,Crane FL,Morré DJ,Löw H,Chou JY

更新日期：1988-06-01 00:00:00

abstract：:The ATP synthetase of chloroplast membranes binds ADP and ATP with high affinity, and the binding becomes quasi-irreversible under certain conditions. One explanation of the function of these nucleotides is that they are transiently tightly bound during ATP synthesis as part of the catalytic process, and that the rele...

journal_title：Journal of bioenergetics and biomembranes

authors： Tiefert MA,Shavit N

更新日期：1983-10-01 00:00:00

abstract：:The advantages of using bacterial systems to study the mechanism and function of cytochrome bc (1) complexes do not extend readily to their structural investigations. High quality crystals of bacterial complexes have been difficult to obtain despite the enzymes' smaller sizes and simpler subunit compositions compared ...

journal_title：Journal of bioenergetics and biomembranes

authors： Xia D,Esser L,Elberry M,Zhou F,Yu L,Yu CA

更新日期：2008-10-01 00:00:00

abstract：:Thirteen different polypeptide subunits, each in one copy, five phosphatidyl ethanolamines and three phosphatidyl glycerols, two hemes A, three Cu ions, one Mg ion, and one Zn ion are detectable in the crystal structure of bovine heart cytochrome c oxidase in the fully oxidized form at 2.8 A resolution. A propionate o...

journal_title：Journal of bioenergetics and biomembranes

authors： Yoshikawa S,Shinzawa-Itoh K,Tsukihara T

更新日期：1998-02-01 00:00:00

abstract：:We have studied changes in plasma membrane NAD(P)H:quinone oxidoreductases of HL-60 cells under serum withdrawal conditions, as a model to analyze cell responses to oxidative stress. Highly enriched plasma membrane fractions were obtained from cell homogenates. A major part of NADH-quinone oxidoreductase in the plasma...

journal_title：Journal of bioenergetics and biomembranes

authors： Forthoffer N,Gómez-Díaz C,Bello RI,Burón MI,Martín SF,Rodríguez-Aguilera JC,Navas P,Villalba JM

更新日期：2002-06-01 00:00:00

abstract：:Many previous investigations have consistently reported that caloric restriction (40%), which increases maximum longevity, decreases mitochondrial reactive species (ROS) generation and oxidative damage to mitochondrial DNA (mtDNA) in laboratory rodents. These decreases take place in rat liver after only seven weeks of...

journal_title：Journal of bioenergetics and biomembranes

authors： Sanz A,Gómez J,Caro P,Barja G

更新日期：2006-12-01 00:00:00

abstract：:For the past seven years or so, much discussion and controversy in the field of human evolution has revolved around the application and interpretation of studies of human mitochondrial DNA variation, particularly the hypothesis that all mtDNA types in contemporary populations can be traced back to a single African anc...

journal_title：Journal of bioenergetics and biomembranes

authors： Stoneking M

更新日期：1994-06-01 00:00:00

abstract：:Previous in vitro studies indicated that mutation of both K234 and K236 to arginine, glutamine, or glutamic acid impaired the ability of the voltage-dependent anion channel (VDAC1) to insert into the outer membrane of the mitochondria (Smith et al. 1995). These same mutants were expressed in a strain of Saccharomyces ...

journal_title：Journal of bioenergetics and biomembranes

authors： Angeles R,Devine J,Barton K,Smith M,McCauley R

更新日期：1999-04-01 00:00:00

abstract：:Hepatic iron toxicity because of iron overload seems to be mediated by lipid peroxidation of biological membranes and the associated organelle dysfunctions. However, the basic mechanisms underlying this process in vivo are still little understood. Gerbils were dosed with weekly injections of iron-dextran alone or in c...

journal_title：Journal of bioenergetics and biomembranes

authors： Masini A,Ceccarelli D,Giovannini F,Montosi G,Garuti C,Pietrangelo A

更新日期：2000-04-01 00:00:00

abstract：:The F1F0 complex of Paracoccus denitrificans (PdF1F0) is the fastest ATP synthase but the slowest ATPase. Sulfite exerts maximal activation of the PdF1F0-ATPase (Pacheco-Moisés, F., García, J. J., Rodríguez-Zavala, J. S., and Moreno-Sánchez, R. (2000). Eur J. Biochem. 267, 993-1000) but its effect on the PdF1F0-ATP sy...

journal_title：Journal of bioenergetics and biomembranes

authors： Pacheco-Moisés F,Minauro-Sanmiguel F,Bravo C,García JJ

更新日期：2002-08-01 00:00:00

abstract：:As the terminal component of the mitochondrial respiratory chain, cytochrome c oxidase plays a vital role in cellular energy transformation. Human cytochrome c oxidase is composed of 13 subunits. The three major subunits form the catalytic core and are encoded by mitochondrial DNA (mtDNA). The remaining subunits are n...

journal_title：Journal of bioenergetics and biomembranes

authors： Taanman JW

更新日期：1997-04-01 00:00:00

abstract：:Plasma membranes isolated from K562 cells contain an NADH-ascorbate free radical reductase activity and intact cells show the capacity to reduce the rate of chemical oxidation of ascorbate leading to its stabilization at the extracellular space. Both activities are stimulated by CoQ10 and inhibited by capsaicin and di...

journal_title：Journal of bioenergetics and biomembranes

authors： Gómez-Díaz C,Rodríguez-Aguilera JC,Barroso MP,Villalba JM,Navarro F,Crane FL,Navas P

更新日期：1997-06-01 00:00:00

abstract：:Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) has been recently identified as a novel inhibitor of multiple tumors; however, its role in glioblastoma (GBM) has not been investigated. This study aimed to evaluate whether LHPP exerts a potential tumor-inhibiting role in GBM. Compared with tha...

journal_title：Journal of bioenergetics and biomembranes

authors： Li C,Yang J,Wang W,Li R

更新日期：2021-02-01 00:00:00

abstract：:2-Arachidonoylglicerol (2-AG) is an endocannabinoid that mimics the pharmacological effects of Δ⁹ tetrahydrocannabinol, the psychoactive component of the plant Cannabis sativa. It is present in many mammalian tissues, such as brain, liver, spleen, heart and kidney, where it exerts different biological effects either r...

journal_title：Journal of bioenergetics and biomembranes

authors： Zaccagnino P,D'Oria S,Romano LL,Di Venere A,Sardanelli AM,Lorusso M

更新日期：2012-04-01 00:00:00

abstract：:NM23s (or NDP kinases) regulate a fascinating variety of cellular activities, including proliferation, development, and differentiation. All these processes are modulated by external stimuli, leading to the idea that this family of proteins modulates transmembrane signaling pathways. This review summarizes the evidenc...

journal_title：Journal of bioenergetics and biomembranes

authors： Otero AS

更新日期：2000-06-01 00:00:00

abstract：:Cellular Ca2+ signals are crucial in the control of most physiological processes, cell injury and programmed cell death; mitochondria play a pivotal role in the regulation of such cytosolic Ca2+ ([Ca2+]c) signals. Mitochondria are endowed with multiple Ca2+ transport mechanisms by which they take up and release Ca2+ a...

journal_title：Journal of bioenergetics and biomembranes

authors： Smaili SS,Hsu YT,Youle RJ,Russell JT

更新日期：2000-02-01 00:00:00