Abstract：
:Atopic dermatitis (AD) is a chronic relapsing-remitting inflammatory skin disorder, characterized by a skin barrier dysfunction resulting in epidermal damage and altered permeability to allergens and microbes. Traditionally, the immunological mechanism involving the Th1-Th2 paradigm is considered central in the pathogenesis of AD. However, oxidative stress is, currently, recognized as a fundamental predisposing stimulus for AD. Several therapeutic approaches have been proposed as treatment, including the use of melatonin. This indolamine, through widespread expression and pleiotropic activity of the cutaneous melatoninergic system, may counteract environmental and endogenous stressors, regulate the immune response, decrease oxidative stress, and, finally, promote skin integrity. In the light of its pleiotropic effects, melatonin could represent a potential and alternative therapeutic approach in patients with AD.
journal_name
J Biol Regul Homeost Agentsjournal_title
Journal of biological regulators and homeostatic agentsauthors
Marseglia L,Cuppari C,Manti S,D'Angelo G,Salpietro C,Reiter RJ,Gitto Esubject
Has Abstractpub_date
2015-04-01 00:00:00pages
142-9issue
2 Suppl 1eissn
0393-974Xissn
1724-6083pii
23journal_volume
29pub_type
杂志文章abstract：:Acute abdominal aortic thrombosis is a rare and potential fatal event, which occurs in adult subjects. We present the case of a 72-year-old-man, who referred to the emergency Department of our hospital because of persistent severe abdominal and perineal pain. Doppler ultrasounds and computerized tomography angiography...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 信件
doi：
更新日期：2013-04-01 00:00:00
abstract：:Three main types of inflammatory Non-Allergic Rhinitis (NAR) have been defined: NAR infiltrated by eosinophils (NARES), by mast cells (NARMA), and by neutrophils (NARNE). In the absence of studies that investigated the Quality of Life (QoL) in NAR, the present work is aimed at evaluating the Quality of Life of patient...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Dysregulation of lncRNA cancer susceptibility candidate 2 (CASC2) is involved in the pathogenesis of multiple malignancies. However, the underlying mechanisms by which lncRNA CASC2 regulates the proliferation of hemangiomas (HAs) remain undocumented. Herein, the expression levels of lncRNA CASC2 and VEGF in proliferat...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：10.23812/19-526-A-FULL_ARTICLE
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abstract：:Throughout the centuries, the undefended nature of man has very often manifested in cases of epidemics, which have determined scenarios of suffering and death. Through “historical” observation lens, it is possible to understand the relationship between the spread of viruses, bacteria and parasites responsible for thes...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
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更新日期：2017-04-01 00:00:00
abstract：:Body weight is controlled by our genes and managed by a neuro-hormonal system, in particular by insulin and glucagon. The meristematic extract of Japanese white mulberry blocks the alpha-glucosidase and then the intestinal hydrolysis of polysaccharides, thereby reducing the glycaemic index of carbohydrates. The target...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 临床试验,信件
doi：
更新日期：2014-01-01 00:00:00
abstract：:We recently identified a rheumatoid factor associated with autoimmune disease resistance and remission, and have named it regulatory rheumatoid factor (regRF). Epitopes recognized by regRF can be induced in papain Fc fragments of IgG. Immunization of arthritic rats with homologous Fc fragments that expose neoepitopes ...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 信件
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更新日期：2019-05-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 信件
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更新日期：2015-10-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2016-10-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 临床试验,杂志文章
doi：
更新日期：2018-03-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 信件
doi：
更新日期：2018-01-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2019-01-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2019-11-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2019-03-01 00:00:00
abstract：:The binding of nuclear proteins from human tumor cells to synthetic double stranded oligonucleotides mimicking upstream regions of the HLA-DR alpha gene was studied. As the HLA-DR alpha gene is inducible by interferon(IFN)-gamma, nuclear extracts were also purified from IFN-gamma treated cells. Our data indicate that ...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：:Heat-induced total body hyperthermia has been shown to synergistically enhance the in vivo antitumor effects of MuIFN-gamma directed against B16 melanoma in mice. This observation was made with an 8-hour exposure to hyperthermia that was administered following MuIFN-gamma treatment. It was not known whether this was t...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2011-04-01 00:00:00
abstract：:There is wide discussion about the association between sport activity and musculoskeletal disorders, as sports-related joint loading increases the risk of osteoarthritis (OA). The present article reviews the current available literature on the connections between participation in several sports and athletic activities...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章,评审
doi：
更新日期：2019-03-01 00:00:00
abstract：:The primary objective of antiretroviral therapy is to suppress viral replication as soon as possible, as much as possible and for as long as possible, a concept so clearly emphasized by David Ho in 1995: "Treat HIV early and hard!". That, however, seems an ideal objective by a number of reasons, recently recognized as...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：:Gastroesophageal reflux disease (GERD) may be frequently associated with asthma in children and may affect asthma control. Proton pump inhibitors (PPI) are commonly prescribed in asthmatic children, despite uncertain efficacy on respiratory symptoms and risk of relevant adverse effects. ...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 信件
doi：
更新日期：2019-03-01 00:00:00
abstract：:Bronchial asthma is a chronic inflammatory disease characterized by bronchial obstruction, usually reversible spontaneously or after therapy, bronchial hyperreactivity and accelerated decrease of lung function that may possibly evolve into irreversible obstruction of the respiratory tract. Bronchial provocation tests ...
journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2015-04-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 信件,meta分析
doi：
更新日期：2018-09-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
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doi：
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：10.23812/19-68-A
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2013-04-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2012-04-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
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更新日期：2019-03-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 杂志文章
doi：
更新日期：2018-11-01 00:00:00
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journal_title：Journal of biological regulators and homeostatic agents
pub_type： 信件
doi：
更新日期：2018-11-01 00:00:00
