Minimum mycophenolic acid levels are associated with donor-specific antibody formation.

abstract：:The majority of transplant centers around the world face an ethical debate whether to retransplant a young non-adherent patient. Non-adherence to lifelong immunosuppressants presents a significant risk for graft loss, yet rates remain consistently high. Despite a number of these patients presenting for retransplantati...

journal_title：Pediatric transplantation

authors： Dobbels F,Hames A,Aujoulat I,Heaton N,Samyn M

更新日期：2012-02-01 00:00:00

abstract：:Cryptosporidium is an intracellular protozoa that can cause gastroenteritis in humans. In immunocompromised hosts, infection can be severe, leading to life-threatening persistent diarrhea. There is limited experience in treating this infection in solid organ transplants. Although newer drugs active against Cryptospori...

journal_title：Pediatric transplantation

authors： Hong DK,Wong CJ,Gutierrez K

更新日期：2007-02-01 00:00:00

abstract：:Treatment of severe aplastic anemia (SAA) patients who lack human leukocyte antigen (HLA)-matched donors and failed immunosuppressive therapy (IST) is challenging. Recently, umbilical cord blood transplantation (CBT) after non-myeloablative therapy has been reported in adult but not in childhood SAA. However, most cas...

journal_title：Pediatric transplantation

authors： Ohga S,Ichino K,Goto K,Hattori S,Nomura A,Takada H,Nakamura K,Hara T

更新日期：2006-06-01 00:00:00

abstract：:Primary graft dysfunction following HTx is associated with significant morbidity and mortality. This study aimed to assess the incidence of, risk factors for, and outcomes of children requiring ECMO within 24 hours of HTx. This study utilized a linked PHIS/SRTR database of pediatric HTx recipients (2002-2016). Post-HT...

journal_title：Pediatric transplantation

authors： Godown J,Bearl DW,Thurm C,Hall M,Feingold B,Soslow JH,Mettler BA,Smith AH,Profita EL,Singh TP,Dodd DA

更新日期：2019-06-01 00:00:00

abstract：:This review details the indications for heart transplantation in children. Contraindications have evolved from absolute to relative. Controversial issues remain and this paper represents a consensus of more than a dozen centers that have programs that remain active performing pediatric heart transplants. ...

journal_title：Pediatric transplantation

authors： Fricker FJ,Addonizio L,Bernstein D,Boucek M,Boucek R,Canter C,Chinnock R,Chin C,Kichuk M,Lamour J,Pietra B,Morrow R,Rotundo K,Shaddy R,Schuette EP,Schowengerdt KO,Sondheimer H,Webber S

更新日期：1999-11-01 00:00:00

abstract：:eHAT is one of the most dreaded post-LT complication. Treatment approaches include retransplantation, revascularization, or observation. Systemic thrombolytic therapy is used in pediatric patients with thromboembolic events. However, there is no previous study reporting on the use of systemic r-tPA to treat eHAT. The ...

journal_title：Pediatric transplantation

authors： Feier FH,Melere MU,Trein CS,da Silva CS,Lucchese A,Horbe A,Tonet F,Ricachinevsky C,Ferreira CT,Chedid MF,Kalil AN

更新日期：2020-10-27 00:00:00

abstract：:Bacillus cereus is a spore-forming, gram-positive bacterium that causes food poisoning presenting with either emesis or diarrhea. Diarrhea is caused by proteinaceous enterotoxin complexes, mainly hemolysin BL, non-hemolytic enterotoxin (NHE), and cytotoxin K. In contrast, emesis is caused by the ingestion of the depsi...

journal_title：Pediatric transplantation

authors： Tschiedel E,Rath PM,Steinmann J,Becker H,Dietrich R,Paul A,Felderhoff-Müser U,Dohna-Schwake C

更新日期：2015-02-01 00:00:00

abstract：:DIDS is a unique form of combined immune deficiency characterized by an unusual susceptibility to cutaneous viral infections, severe allergies with eosinophilia and elevated immunoglobulin E titers, autoimmunity, and cancer. HSCT is considered the standard of care for this deadly disease. We have retrospectively analy...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Reisli İ,Keleş S,Özen A,Yılmaz M,Sayar EH,Daloğlu H,Öztürkmen SI,Çakı S,Karasu GT,Yeşilipek A

更新日期：2017-11-01 00:00:00

abstract：:Abdominal wall closure after pediatric liver transplantation (pLT) in infants may be hampered by graft-to-recipient size discrepancy. Herein, we describe the use of a porcine dermal collagen acellular graft (PDCG) as a biological mesh (BM) for abdominal wall closure in pLT recipients. Patients <2 years of age, who und...

journal_title：Pediatric transplantation

authors： Gül-Klein S,Dziodzio T,Martin F,Kästner A,Witzel C,Globke B,Jara M,Ritschl PV,Henning S,Gratopp A,Bufler P,Schöning W,Schmelzle M,Pratschke J,Öllinger R

更新日期：2020-05-01 00:00:00

abstract：:IHHE as the most common vascular tumor of the liver in infancy can present with acute postnatal liver and congestive heart failure. LTx may be a lifesaving option, but can be complicated by extrahepatic involvement and bleeding complications, especially in neonates. Here we discuss the benefit of LTx in cases of acute...

journal_title：Pediatric transplantation

authors： Grabhorn E,Richter A,Fischer L,Krebs-Schmitt D,Ganschow R

更新日期：2009-08-01 00:00:00

abstract：:In the pediatric population, little is known on de novo DSA development, its impact on graft function, and association with suboptimal IS. We assessed the prevalence of de novo DSA in the Vienna cohort of 40 renal transplanted children and adolescents and prospectively followed its association with clinical parameters...

journal_title：Pediatric transplantation

authors： Rusai K,Dworak J,Potemkina A,Fischer G,Csaicsich D,Arbeiter K,Aufricht C,Müller-Sacherer T

更新日期：2016-06-01 00:00:00

abstract：:Hypogammaglobulinemia is common after pediatric SCT and IgG replacement is recommended. Some children will have a prolonged hypogammaglobulinemia but may have poor venous access which impedes further iv IgG replacement. In primary antibody deficiencies, sc IgG replacement, performed by parents at home, has been shown ...

journal_title：Pediatric transplantation

authors： Sundin M,Nordin K,Jostemyr Y,Winiarski J

更新日期：2012-12-01 00:00:00

abstract：:Liver and small bowel transplant is an established treatment for infants with IFALD. Despite organ reduction techniques, mortality on the waiting list remains high due to shortage of size-matched pediatric donors. Small abdominal cavity volume due to previous intestinal resection poses a significant challenge to achie...

journal_title：Pediatric transplantation

authors： Vidyadharan R,van Bommel AC,Kuti K,Gupte GL,Sharif K,Richard BM

更新日期：2013-11-01 00:00:00

abstract：AIMS:We investigated interrelations between cognitive abilities, behavioural problems, quality of life and disease-related variables of children after LTX. METHODS:Our sample consisted of 25 children. They were 8.5/2.8 (M/SD) years old and had received the transplant 5.5/3.1 years previously. For assessment we used we...

journal_title：Pediatric transplantation

authors： Kaller T,Boeck A,Sander K,Richterich A,Burdelski M,Ganschow R,Schulz KH

更新日期：2010-06-01 00:00:00

abstract：:FA is an autosomal recessive disorder characterized by small stature and renal abnormalities. FA can lead to progressive bone marrow failure, myelodysplastic syndrome, or acute leukemia. Using a multidisciplinary team approach, we managed a 3-yr-old boy with FA who simultaneously developed renal and hematopoietic fail...

journal_title：Pediatric transplantation

authors： Vincent CL,Primack WA,Hipps J,Kasow KA

更新日期：2016-02-01 00:00:00

abstract：:Many pediatric centers utilize a variety of protocols including preemptive plasmapheresis to prevent the recurrence of FSGS post-transplant. But the effectiveness of this expensive, time-consuming process of plasmapheresis in the prevention of FSGS recurrence is still unclear. We retrospectively reviewed all pediatric...

journal_title：Pediatric transplantation

authors： Verghese PS,Rheault MN,Jackson S,Matas AJ,Chinnakotla S,Chavers B

更新日期：2018-05-01 00:00:00

abstract：:Major neurologic complications secondary to cyclosporine are well documented and are known to include confusion, cortical blindness, seizure, spasticity, paresis, ataxia and coma. Most previous reports attribute these to white matter central nervous system (CNS) lesions or white/grey matter border lesions. Many predis...

journal_title：Pediatric transplantation

authors： Jeruss J,Braun SV,Reese JC,Guillot A

更新日期：1998-02-01 00:00:00

abstract：:Non-adherence to immunosuppressant medications is an important risk factor for graft dysfunction. To evaluate the effectiveness of adherence-enhancing interventions, we reviewed adherence intervention studies in solid organ transplant recipients (all ages). Using the following databases: PsycINFO, PubMed, Scopus, and ...

journal_title：Pediatric transplantation

authors： Duncan S,Annunziato RA,Dunphy C,LaPointe Rudow D,Shneider BL,Shemesh E

更新日期：2018-02-01 00:00:00

abstract：:Vitamin C deficiency in developed countries is typically observed in patients with unique clinical conditions such as cystic fibrosis or anorexia nervosa, or in patients on long-term tube feeds. We report here a clinical observation in six pediatric and adolescent patients (median age 17.5 yr, range 9.8-23.5 yr) with ...

journal_title：Pediatric transplantation

authors： Kletzel M,Powers K,Hayes M

更新日期：2014-08-01 00:00:00

abstract：:There are few studies on invasive pneumococcal disease in pediatric transplant recipients. Given this fact plus the advent of pneumococcal conjugate vaccines, we conducted a retrospective study at a major pediatric transplant center. The objectives were to determine the incidence and outcomes of invasive pneumococcal ...

journal_title：Pediatric transplantation

authors： Tran L,Hébert D,Dipchand A,Fecteau A,Richardson S,Allen U

更新日期：2005-04-01 00:00:00

abstract：:A generic version of tacrolimus was approved for use in the USA in August 2009. These narrow therapeutic index generics are tested for bioequivalence only in adults. No data are available on generic tacrolimus levels in children with allografts. Four patients with stable renal allografts in our pediatric program were ...

journal_title：Pediatric transplantation

authors： Abdulnour HA,Araya CE,Dharnidharka VR

更新日期：2010-12-01 00:00:00

abstract：:Controversy exists over whether PHTN in heart transplant candidates increases post-transplant mortality. We performed analysis of data reported to UNOS for children who underwent primary heart transplantation for cardiomyopathy from January 1994 to June 2010. Patients were divided into two groups depending on their pr...

journal_title：Pediatric transplantation

authors： Buddhe S,Du W,L'Ecuyer T

更新日期：2012-06-01 00:00:00

abstract：:In the past 20 yr, a dramatic improvement has been achieved in the outcome of children with hepatoblastoma by combining cisplatin based chemotherapy and surgery. Treatment of patients in the USA is an exception to the rule that all patients should receive neoadjuvant chemotherapy. It is paramount that surgical resecti...

journal_title：Pediatric transplantation

authors： Otte JB,de Ville de Goyet J,Reding R

更新日期：2005-10-01 00:00:00

abstract：:De novo PTAID may develop in pediatric solid organ transplant recipients, have a diverse spectrum, and are occasionally treatment resistant. Previous reports showed resolution of immune cytopenias in solid organ transplant recipients following replacement of the calcineurin inhibitor tacrolimus with the mTOR inhibitor...

journal_title：Pediatric transplantation

authors： Kehar M,Grunebaum E,Jimenez-Rivera C,Mozer-Glassberg Y,Jamal A,Ng VL,Avitzur Y

更新日期：2020-09-01 00:00:00

abstract：:The aim of this study was to analyze the impact of TAC on medium term (three-yr follow-up) renal function in pediatric liver transplant (OLT) recipients. Glomerular and tubular indices were retrospectively analyzed in 24 consecutive OLT pediatric recipients on TAC. CrCl increased significantly each month post-OLT (p =...

journal_title：Pediatric transplantation

authors： Anastaze Stelle K,Belli DC,Parvex P,Girardin E,Giroud A,Wildhaber B,McLin VA

更新日期：2012-05-01 00:00:00

abstract：:Calcineurin inhibitors post-renal transplantation are recognized to cause tubulopathies in the form of hyponatremia, hyperkalemia, and acidosis. Sodium supplementation may be required, increasing medication burden and potentially resulting in poor compliance. Fludrocortisone has been beneficial in addressing tubulopat...

journal_title：Pediatric transplantation

authors： Ali SR,Shaheen I,Young D,Ramage I,Maxwell H,Hughes DA,Athavale D,Shaikh MG

更新日期：2018-03-01 00:00:00

abstract：:HPS is defined as arterial hypoxemia because of pulmonary vasodilation as a result of cirrhotic or non-cirrhotic portal hypertension. This report describes a teenager with HPS because of primary sclerosing cholangitis/autoimmune hepatitis overlap syndrome requiring OLT. HPS resolved completely within three months of O...

journal_title：Pediatric transplantation

authors： Rajwal SR,Davison SM,Prasad R,Brownlee K,McClean P

更新日期：2007-12-01 00:00:00

abstract：:Pediatric solid organ transplant recipients have long-standing malnutrition concerns related to their pretransplant medical status. The targeted nutrition therapy utilized pre-, peri-, and post-transplantation may have the adverse effect of impeding normally developing feeding skills, particularly in very young childr...

journal_title：Pediatric transplantation

authors： Lerret SM,Erato G,Goday PS,Silverman AH

更新日期：2019-05-01 00:00:00

abstract：:Myocarditis represents an important cause for acute heart failure. MYKKE, a prospective multicenter registry of pediatric patients with myocarditis, aims to gain knowledge on courses, diagnostics, and therapy of pediatric myocarditis. The role of mechanical circulatory support (MCS) in children with severe heart failu...

journal_title：Pediatric transplantation

authors： Schubert S,Opgen-Rhein B,Boehne M,Weigelt A,Wagner R,Müller G,Rentzsch A,Zu Knyphausen E,Fischer M,Papakostas K,Wiegand G,Ruf B,Hannes T,Reineker K,Kiski D,Khalil M,Steinmetz M,Fischer G,Pickardt T,Klingel K,Messr

更新日期：2019-11-01 00:00:00

abstract：:Neoplasms in children after organ transplantation are related to the type and intensity of immunosuppression and the donor-recipient serostatus, especially in relation to the Epstein-Barr virus. The patient was a two-yr-old female child with biliary atresia who underwent a liver transplantation from a female cadaver d...

journal_title：Pediatric transplantation

authors： Backes AN,Tannuri AC,de Mello ES,Gibelli NE,de Castro Andrade W,Tannuri U

更新日期：2012-12-01 00:00:00