Effect of interleukin-2 receptor antagonists on new-onset diabetes after liver transplantation: A retrospective cohort study.

abstract：BACKGROUND:Liver X receptors (LXRs) including LXRα and LXRβ are members of the nuclear hormone receptor superfamily of ligand activated transcription factors, which serve as lipid sensors to regulate expression of genes controlling many aspects of cholesterol and fatty acid metabolism. The liver is the central organ in...

journal_title：Journal of diabetes

authors： Zhang X,Liu J,Su W,Wu J,Wang C,Kong X,Gustafsson JÅ,Ding J,Ma X,Guan Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Currently, there is no consensus regarding the medical treatment of chronic Charcot neuroarthropathy (CN) of foot, except for effective off-loading. Because tarsal bones are predominantly trabecular, teriparatide may improve the macroarchitecture of foot bones in chronic CN. METHODS:People with diabetes and...

journal_title：Journal of diabetes

authors： Rastogi A,Hajela A,Prakash M,Khandelwal N,Kumar R,Bhattacharya A,Mittal BR,Bhansali A,Armstrong DG

更新日期：2019-09-01 00:00:00

abstract：:Two years ago, data presented at the annual American Diabetes Association (ADA) meeting in New Orleans showed a marked decrease in deaths, especially those due to cardiovascular disease, with the use of empagliflozin. Two major questions have been asked: (i) was the result a fluke; and (ii) was it a class effect, or w...

journal_title：Journal of diabetes

authors： Drexler A

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Although niacin often has beneficial effects on the lipoprotein profile, flushing is an untoward effect associated with its use. Aspirin can only reduce the flushing response by 30-40%. Thus, the aim of the present study was to investigate the mechanisms of niacin-induced flushing, with and without aspirin, ...

journal_title：Journal of diabetes

authors： Parson HK,Harati H,Cooper D,Vinik AI

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Considerable uncertainty remains about obstructive lung function( OLF) in adults with metabolic syndrome (MetS). The aim of the present study was to examine pulmonary function status in adults with and without MetS. METHODS:We used data from 3109 participants aged ≥20 years of the National Health and Nutrit...

journal_title：Journal of diabetes

authors： Ford ES,Cunningham TJ,Mercado CI

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Elevated blood or urinary concentrations of endocrine-disrupting chemicals (EDCs) may be related to increased risk of type 2 diabetes (T2D). The aim of the present study was to assess the role of EDCs in affecting risk of T2D and related metabolic traits. METHODS:MEDLINE was searched for cross-sectional and...

journal_title：Journal of diabetes

authors： Song Y,Chou EL,Baecker A,You NC,Song Y,Sun Q,Liu S

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:To investigate the effect of hydroxypropyl methylcellulose (HPMC) on weight loss and metabolic disorders associated with obesity using a high-fat diet-induced obese mouse model under a high-fat diet regimen. METHODS: Obese male C57BL/6J (B6) mice were fed either a high-fat (60% kcal), low-fat (10% kcal), or...

journal_title：Journal of diabetes

authors： Hung SC,Anderson WH,Albers DR,Langhorst ML,Young SA

更新日期：2011-06-01 00:00:00

abstract：:This article reviews the known pathophysiological mechanisms of comorbid gastroesophageal reflux disease (GERD) in the diabetic patient, discusses therapeutic options in care, and provides an approach to its evaluation and management. We searched for review articles published in the past 10 years through a PubMed sear...

journal_title：Journal of diabetes

authors： Punjabi P,Hira A,Prasad S,Wang X,Chokhavatia S

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Limited information exists regarding the efficacy of pregabalin in Chinese patients with painful diabetic peripheral neuropathy (pDPN). METHODS:An 11-week double-blind placebo-controlled trial was performed in Chinese pDPN patients randomized (1 : 1) to 300 mg/day pregabalin or placebo. The primary outcome ...

journal_title：Journal of diabetes

authors： Mu Y,Liu X,Li Q,Chen K,Liu Y,Lv X,Xu X,Fan D,Shang N,Yang R,Pauer L,Pan C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Atherosclerosis may be stimulated by the increased presence of insulin and tumor necrosis-factor-α (TNFα) with subsequent expression of vascular cell adhesion molecule-1 (VCAM-1). We hypothesized that extracellular signal-regulated kinase-5 (ERK5) plays an important role in insulin and TNFα-stimulated total ...

journal_title：Journal of diabetes

authors： Mackesy DZ,Goalstone ML

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:G protein-coupled receptor kinase-2 (GRK2) has been shown as a key regulator of cardiac function, and the myocardial GRK2 levels are mirrored by the levels in peripheral blood mononuclear cells (PBMCs). In this study, we evaluated the myocardial and PBMCs GRK2 levels in early diabetic cardiomyopathy (DCM). ...

journal_title：Journal of diabetes

authors： Lai S,Fu X,Yang S,Zhang S,Lin Q,Zhang M,Chen H

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:This meta-analysis was performed to quantitatively evaluate the dose-response association between obstructive sleep apnea (OSA) and risk of type 2 diabetes mellitus (T2DM). METHODS:PubMed, Embase, and Web of Science were searched up to 12 December 2018 for articles that assessed the OSA-T2DM association. Ra...

journal_title：Journal of diabetes

authors： Qie R,Zhang D,Liu L,Ren Y,Zhao Y,Liu D,Liu F,Chen X,Cheng C,Guo C,Li Q,Zhou Q,Tian G,Han M,Huang S,Wu X,Qin P,Li J,Cao J,Zhang M,Huang J,Lu J,Li H,Wang J,Cheng R,Hu D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Asia is experiencing a type 2 diabetes epidemic, but prevalence differs by ethnicity and level of socioeconomic development. Singapore and Mauritius have implemented comprehensive campaigns to address this public health problem. We compared diabetes and obesity prevalence trends among Chinese and South Asian...

journal_title：Journal of diabetes

authors： Tan KHX,Barr ELM,Koshkina V,Ma S,Kowlessur S,Magliano DJ,Söderberg S,Chia KS,Zimmet P,Lim WY

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Supervised treadmill exercise is the recommended therapy for peripheral arterial disease (PAD) patients with intermittent claudication (IC). However, most PAD patients do not exhibit typical symptoms of IC. The aim of the present study was to explore the efficacy and safety of intensive walking exercise in P...

journal_title：Journal of diabetes

authors： Lyu X,Li S,Peng S,Cai H,Liu G,Ran X

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to investigate whether the therapeutic efficacy of acarbose and metformin is correlated with baseline HbA1c levels in Chinese patients with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS:Data for 711 subjects were retrieved from the MARCH (Metformin and AcaRbose in...

journal_title：Journal of diabetes

authors： Zhang JP,Wang N,Xing XY,Yang ZJ,Wang X,Yang WY

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:In addition to its glucoregulatory actions, exendin-4, a stable glucagon-like peptide-1 receptor agonist, exhibits protective effects in the pancreas and anti-obesity effects. Suitable combination treatment with other anti-obesity or pancreas protective agents would be an effective approach to optimize these...

journal_title：Journal of diabetes

authors： Patel V,Joharapurkar A,Gandhi T,Patel K,Dhanesha N,Kshirsagar S,Dhote V,Detroja J,Bahekar R,Jain M

更新日期：2013-06-01 00:00:00

abstract：:There has been a rapid escalation of type 2 diabetes (T2D) in developing countries, with varied prevalence according to rural vs urban habitat and degree of urbanization. Some ethnic groups (eg, South Asians, other Asians, and Africans), develop diabetes a decade earlier and at a lower body mass index than Whites, hav...

journal_title：Journal of diabetes

authors： Misra A,Gopalan H,Jayawardena R,Hills AP,Soares M,Reza-Albarrán AA,Ramaiya KL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Insulin therapy should be strongly considered in newly diagnosed type 2 diabetic (T2D) patients with severe hyperglycemia. However, whether insulin be continued or patients switched to an oral antidiabetic drug (OAD) after short-term intensive insulin therapy (ITT) is not clear. METHODS:After ITT for 10-14 ...

journal_title：Journal of diabetes

authors： Cheng Q,Yang S,Zhao C,Wang Z,Feng Z,Li R,Ye P,Zhang S,Deng H,Zhou B,Long J,Gong L,Qing H,Luo C,Li Q

更新日期：2015-03-01 00:00:00

abstract：:Following on from impressive economic development and urbanization, China is currently experiencing a high prevalence of metabolic syndrome. Patients with metabolic syndrome suffer from the "The Deadly Quartet" of hyperglycemia, hypertriglyceridemia, hypertension, and central (or upper body) obesity. Current treatment...

journal_title：Journal of diabetes

authors： Xia X,Weng J

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Few studies have focused on postprandial incretin responses to different carbohydrate meals. Therefore, we designed a study to compare the different effects of two carbohydrates (75 g oral glucose, a monosaccharide and 100 g standard noodle, a polysaccharide, with 75 g carbohydrates equivalently) on postpran...

journal_title：Journal of diabetes

authors： Deng Y,Zhang Y,Zheng S,Hong J,Wang C,Liu T,Sun Z,Gu W,Gu Y,Shi J,Yao S,Wang W,Ning G

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The present study investigated the correlation between urinary α1 -microglobulin as a marker of tubular dysfunction and albumin excretion in children and adolescents with type 1 diabetes (T1D). METHODS:Ninety-two Egyptian patients with T1D were included in the study (mean [± SD] age 14.14 ± 5.13 years). The...

journal_title：Journal of diabetes

authors： Saif A,Soliman N

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Dipeptidyl peptidase-4 (DPP-4) is responsible for degradation of glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP), the endogenous incretins that stimulate glucose-dependent insulin secretion. The objective was to evaluate preclinical profile of a novel DPP-4 inhibitor ZYDPLA1. METHODS...

journal_title：Journal of diabetes

authors： Jain MR,Joharapurkar AA,Bahekar RH,Patel H,Jadav P,Kshirsagar SG,Patel VJ,Patel KN,Ramanathan VK,Patel PR,Desai RC

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) is highly prevalent worldwide, and its individual components obesity, diabetes, and hypertension have been identified as risk factors to develop severe coronavirus disease 2019 (COVID-19); however, data on MetS and clinical outcomes in COVID-19 are scarce. This study aims to determi...

journal_title：Journal of diabetes

authors： Lohia P,Kapur S,Benjaram S,Pandey A,Mir T,Seyoum B

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND:Cross-sectional studies have supported the association among depression, obesity, and type 2 diabetes, but the causality remains controversial in Chinese adults. In this longitudinal study, we evaluated the synergistic effect of depression and obesity on the risk of type 2 diabetes. METHODS:This study inclu...

journal_title：Journal of diabetes

authors： Ning F,Zhang D,Xue B,Zhang L,Zhang J,Zhu Z,Zhang D,Gao R,Pang Z,Qiao Q,Qingdao Diabetes Prevention Program.

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus (T2DM) treatment generally requires multiple antihyperglycemic agents. When diet, exercise, and treatment with sulfonylurea and metformin do not achieve glycemic goals, several options are available. The present study evaluated the efficacy and tolerability of sitagliptin 100 mg/day ...

journal_title：Journal of diabetes

authors： Moses RG,Round E,Shentu Y,Golm GT,O'neill EA,Gantz I,Engel SS,Kaufman KD,Goldstein BJ

更新日期：2016-09-01 00:00:00

abstract：:Crossover design has been widely used in late-phase clinical studies, as well as in pharmacokinetic and pharmacodynamic, bioequivalence, and medical device studies; however, its interpretability and applicability continue to be debated. Herein we provide discussions around a crossover design's scientific benefit, appl...

journal_title：Journal of diabetes

authors： Wang T,Malone J,Fu H,Heilmann C,Qu Y,Huster WJ

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Adipocyte fatty acid-binding protein (A-FABP) has been recognized as an important player in macrophage cholesterol trafficking and inflammation, and may promote the development of atherosclerosis. To further elucidate the role of A-FABP in atherosclerosis in diabetes, we investigated the relationship between...

journal_title：Journal of diabetes

authors： Ding M,Shi JY,Xing YZ,Sun B,Fang QH,Zhang JY,Zhang QM,Chen LM,Yu DM,Li CJ

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus affects the systolic and diastolic function of the left ventricle (LV). The aim of the present study was to evaluate the index of myocardial performance (IMP), a new Doppler index, in asymptomatic, normotensive patients with type 2 diabetes mellitus (T2DM). METHODS:The study population con...

journal_title：Journal of diabetes

authors： Saglam H,Seyfeli E,Gul I,Duru M,Gokce C

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Brown adipose tissue (BAT) has been regarded as a potential target organ to combat obesity and related metabolic disorders. However, the effect of BAT activation on the development of diabetic kidney disease (DKD) remains unclear. METHODS:Diabetic mice were induced by streptozotocin (STZ) combined with a hi...

journal_title：Journal of diabetes

authors： Cai YY,Zhang HB,Fan CX,Zeng YM,Zou SZ,Wu CY,Wang L,Fang S,Li P,Xue YM,Guan MP

更新日期：2019-12-01 00:00:00

abstract：:Highlights A large retrospective study indicates no association between GDM and most types of cancer; this is in contrast to a few smaller studies that have suggested an association with cancer. An increased risk of thyroid cancer in mothers with GDM was demonstrated. While this risk requires further investigation, it...

journal_title：Journal of diabetes

authors： Pace R,Rahme E,Dasgupta K

更新日期：2020-01-01 00:00:00