A sinemydid turtle from the Jehol Biota provides insights into the basal divergence of crown turtles.

abstract：:Dehydroascorbate reductase (DHAR) is a key enzyme involved in the recycling of ascorbate, which catalyses the glutathione (GSH)-dependent reduction of oxidized ascorbate (dehydroascorbate, DHA). As a result, DHAR regenerates a pool of reduced ascorbate and detoxifies reactive oxygen species (ROS). In previous experime...

journal_title：Scientific reports

authors： Do H,Kim IS,Jeon BW,Lee CW,Park AK,Wi AR,Shin SC,Park H,Kim YS,Yoon HS,Kim HW,Lee JH

更新日期：2016-01-18 00:00:00

abstract：:There is a growing need for biolabels that can be used in both optical and electron microscopies, are non-cytotoxic, and do not photobleach. Such biolabels could enable targeted nanoscale imaging of sub-cellular structures, and help to establish correlations between conjugation-delivered biomolecules and function. Her...

journal_title：Scientific reports

authors： Zurbuchen MA,Lake MP,Kohan SA,Leung B,Bouchard LS

更新日期：2013-01-01 00:00:00

abstract：:The synthetic cyclic hexapeptide cWFW (cyclo(RRRWFW)) has a rapid bactericidal activity against both Gram-positive and Gram-negative bacteria. Its detailed mode of action has, however, remained elusive. In contrast to most antimicrobial peptides, cWFW neither permeabilizes the membrane nor translocates to the cytoplas...

journal_title：Scientific reports

authors： Scheinpflug K,Wenzel M,Krylova O,Bandow JE,Dathe M,Strahl H

更新日期：2017-03-09 00:00:00

abstract：:Mounting evidence indicated that human mesenchymal stem cells (hMSCs) are responsive not only to biochemical but also to physical cues, such as substrate topography and stiffness. To simulate the dynamic structures of extracellular environments of the marrow in vivo, we designed a novel surrogate substrate for marrow ...

journal_title：Scientific reports

authors： Frank V,Kaufmann S,Wright R,Horn P,Yoshikawa HY,Wuchter P,Madsen J,Lewis AL,Armes SP,Ho AD,Tanaka M

更新日期：2016-04-15 00:00:00

abstract：:Laser speckle flowmetry suffers from a debated quantification of the inverse relation between decorrelation time (τc) and blood flow velocity (V), i.e. 1/τc = αV. Using a modified microcirculation imager (integrated sidestream dark field - laser speckle contrast imaging [SDF-LSCI]), we experimentally investigate on th...

journal_title：Scientific reports

authors： Nadort A,Kalkman K,van Leeuwen TG,Faber DJ

更新日期：2016-04-29 00:00:00

abstract：:Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researching space to redesign the textured structures. Here is presented a route to obtain a new die-upset magnet with substantially improved magnetic properties. After experiencing the optimized heat treatment, both the coercivi...

journal_title：Scientific reports

authors： Wang Z,Ju J,Wang J,Yin W,Chen R,Li M,Jin C,Tang X,Lee D,Yan A

更新日期：2016-12-06 00:00:00

abstract：:During Antarctic isolation personnel are exposed to extreme photoperiods. A frequent observation is a sleep onset phase delay during winter. It is not known if, as a result, daytime sleeping in the form of naps increases. We sought to assess sleep patterns - with focus on daytime sleeping - and alertness in a Latin Am...

journal_title：Scientific reports

authors： Folgueira A,Simonelli G,Plano S,Tortello C,Cuiuli JM,Blanchard A,Patagua A,Brager AJ,Capaldi VF,Aubert AE,Barbarito M,Golombek DA,Vigo DE

更新日期：2019-07-26 00:00:00

abstract：:Local communities are assembled from larger-scale species pools via dispersal, environmental filtering, biotic interactions, and local stochastic demographic processes. The relative importance, scaling and interplay of these assembly processes can be elucidated by comparing local communities to variously circumscribed...

journal_title：Scientific reports

authors： Feng G,Mi X,Eiserhardt WL,Jin G,Sang W,Lu Z,Wang X,Li X,Li B,Sun I,Ma K,Svenning JC

更新日期：2015-03-23 00:00:00

abstract：:Hemodialysis patients are a special group of patients with higher mortality rates. Hemodialysis patients with vitamin D deficiency {plasma levels of 25-hydroxyvitamin D [25(OH)D] below 20 ng/mL} are associated with even higher mortality rates. The prognostic importance of vitamin D deficiency in hemodialysis patients ...

journal_title：Scientific reports

authors： Hsu HJ,Wu IW,Hsu KH,Sun CY,Chen CY,Lee CC

更新日期：2020-05-05 00:00:00

abstract：:Natural hazards including floods can trigger catastrophic failures in interdependent urban transport network-of-networks (NoNs). Population growth has enhanced transportation demand while urbanization and climate change have intensified urban floods. However, despite the clear need to develop actionable insights for i...

journal_title：Scientific reports

authors： Yadav N,Chatterjee S,Ganguly AR

更新日期：2020-06-25 00:00:00

abstract：:Tetrastatin, a 230 amino acid sequence from collagen IV, was previously demonstrated to inhibit melanoma progression. In the present paper, we identified the minimal active sequence (QKISRCQVCVKYS: QS-13) that reproduced the anti-tumor effects of whole Tetrastatin in vivo and in vitro on melanoma cell proliferation, m...

journal_title：Scientific reports

authors： Lambert E,Fuselier E,Ramont L,Brassart B,Dukic S,Oudart JB,Dupont-Deshorgue A,Sellier C,Machado C,Dauchez M,Monboisse JC,Maquart FX,Baud S,Brassart-Pasco S

更新日期：2018-06-29 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Sameni S,Malacrida L,Tan Z,Digman MA

更新日期：2018-04-11 00:00:00

abstract：:Large-strain elastic superhydrophobicity is highly desirable for its enhanced use performance and functional reliability in mechanically dynamic environments, but remains challenging to develop. Here we have, for the first time, proven that an elastic fibrous membrane after surface hydrophobization can maintain superh...

journal_title：Scientific reports

authors： Zhou H,Wang H,Niu H,Lin T

更新日期：2015-10-29 00:00:00

abstract：:Drug delivery by micro- and nano-carriers enables controlled transport of pharmaceuticals to targeted sites. Even though carrier fabrication has made much progress recently, the delivery including controlled particle distribution and adhesion within the body remains a great challenge. The adhesion of carriers is stron...

journal_title：Scientific reports

authors： Müller K,Fedosov DA,Gompper G

更新日期：2014-05-02 00:00:00

abstract：:The evolution of cooperation is a fundamental problem in biology, especially for non-relatives, where indirect fitness benefits cannot counter within-group inequalities. Multilevel selection models show how cooperation can evolve if it generates a group-level advantage, even when cooperators are disadvantaged within t...

journal_title：Scientific reports

authors： Shaffer Z,Sasaki T,Haney B,Janssen M,Pratt SC,Fewell JH

更新日期：2016-07-28 00:00:00

abstract：:The development of a miniaturised device that provides efficient beam manipulation with high transmittance is extremely desirable for the broad range of applications including holography, metalens, and imaging. Recently, the potential of dielectric metasurfaces has been unleashed to efficiently manipulate the beam wit...

journal_title：Scientific reports

authors： Aoni RA,Rahmani M,Xu L,Zangeneh Kamali K,Komar A,Yan J,Neshev D,Miroshnichenko AE

更新日期：2019-04-24 00:00:00

abstract：:Spinal cord injury (SCI) is frequently accompanied by a degree of spontaneous functional recovery. The underlying mechanisms through which such recovery is generated remain elusive. In this study, we observed a significant spontaneous motor function recovery 14 to 28 days after spinal cord transection (SCT) in rats. U...

journal_title：Scientific reports

authors： Liu W,Shang FF,Xu Y,Belegu V,Xia L,Zhao W,Liu R,Wang W,Liu J,Li CY,Wang TH

更新日期：2015-11-23 00:00:00

abstract：:In the aftermath of the financial crisis of 2007-2009, the growing body of literature on financial networks has widely documented the predictive power of topological characteristics (e.g., degree centrality measures) to explain the systemic impact or systemic exposure of financial institutions. This study shows that c...

journal_title：Scientific reports

authors： Gandica Y,Béreau S,Gnabo JY

更新日期：2020-10-19 00:00:00

abstract：:Animal models are extensively used to evaluate the in vivo functionality of novel drug delivery systems (DDS). However, many variations likely exist in vivo between the animals and human physiological environment that significantly alter results obtained with animal models relative to human system. To date, it is not ...

journal_title：Scientific reports

authors： Namdee K,Carrasco-Teja M,Fish MB,Charoenphol P,Eniola-Adefeso O

更新日期：2015-06-26 00:00:00

abstract：:A hypereutectic Al-Fe-Cu alloy with a high-volume fraction ferro-aluminum second phase (AlFe phases for short) was reheated in the solid-liquid region and the microstructure evolution was investigated. During semisolid heating, the high-melting AlFe phases in the Al-Fe-Cu alloy were demonstrated to stunt the grain gro...

journal_title：Scientific reports

authors： Wang W,Liu B

更新日期：2021-01-15 00:00:00

abstract：:Huntington's disease (HD) is a genetically-determined neurodegenerative disease. Characterising neuropathology in mouse models of HD is commonly restricted to cross-sectional ex vivo analyses, beset by tissue fixation issues. In vivo longitudinal magnetic resonance imaging (MRI) allows for disease progression to be pr...

journal_title：Scientific reports

authors： Steventon JJ,Trueman RC,Ma D,Yhnell E,Bayram-Weston Z,Modat M,Cardoso J,Ourselin S,Lythgoe M,Stewart A,Rosser AE,Jones DK

更新日期：2016-09-01 00:00:00

abstract：:Magnesium-based thermoelectric materials (Mg2X, X = Si, Ge, Sn) have received considerable attention due to their availability, low toxicity, and reasonably good thermoelectric performance. The synthesis of these materials with high purity is challenging, however, due to the reactive nature and high vapour pressure of...

journal_title：Scientific reports

authors： Santos R,Nancarrow M,Dou SX,Aminorroaya Yamini S

更新日期：2017-06-21 00:00:00

abstract：:Anti-mucin1 (MUC1) antibodies have long been used clinically in cancer diagnosis and therapy and specific bindings of some of them are known to be dependent on the differential glycosylation of MUC1. However, a systematic comparison of the binding specificities of anti-MUC1 antibodies was not previously conducted. Her...

journal_title：Scientific reports

authors： Yoshimura Y,Denda-Nagai K,Takahashi Y,Nagashima I,Shimizu H,Kishimoto T,Noji M,Shichino S,Chiba Y,Irimura T

更新日期：2019-11-12 00:00:00

abstract：:Pseudorabies virus (PRV) is a pathogen of swine resulting in devastating disease and economic losses worldwide. Resveratrol (Res) exhibits inhibitory activity against a wide range of viruses. Despite these important advances, the molecular mechanism(s) by which Res exerts its broad biological effects have not yet been...

journal_title：Scientific reports

authors： Zhao X,Cui Q,Fu Q,Song X,Jia R,Yang Y,Zou Y,Li L,He C,Liang X,Yin L,Lin J,Ye G,Shu G,Zhao L,Shi F,Lv C,Yin Z

更新日期：2017-08-18 00:00:00

abstract：:The protein interface is key to understand protein function, providing a vital insight on how proteins interact with each other and with other molecules. Over the years, many computational methods to compare protein structures were developed, yet evaluating interface similarity remains a very difficult task. Here, we ...

journal_title：Scientific reports

authors： Budowski-Tal I,Kolodny R,Mandel-Gutfreund Y

更新日期：2018-05-29 00:00:00

abstract：:Psychopathy is a personality disorder characterised by atypical moral behaviour likely rooted in atypical affective/motivational processing, as opposed to an inability to judge the wrongness of an action. Guilt is a moral emotion believed to play a crucial role in adherence to moral and social norms, but the mechanism...

journal_title：Scientific reports

authors： Seara-Cardoso A,Sebastian CL,McCrory E,Foulkes L,Buon M,Roiser JP,Viding E

更新日期：2016-11-03 00:00:00

abstract：:We aimed to predict molecular subtypes of breast cancer using radiomics signatures extracted from synthetic mammography reconstructed from digital breast tomosynthesis (DBT). A total of 365 patients with invasive breast cancer with three different molecular subtypes (luminal A + B, luminal; HER2-positive, HER2; triple...

journal_title：Scientific reports

authors： Son J,Lee SE,Kim EK,Kim S

更新日期：2020-12-09 00:00:00

abstract：:N-doped carbon nanosheets/vanadium nitride nanoparticles (N-CNS/VNNPs) are synthesized via a novel method combining surface-initiated in-situ intercalative polymerization and thermal-treatment process in NH3/N2 atmosphere. The pH value of the synthesis system plays a critical role in constructing the structure and enh...

journal_title：Scientific reports

authors： Tan Y,Liu Y,Tang Z,Wang Z,Kong L,Kang L,Liu Z,Ran F

更新日期：2018-02-13 00:00:00

abstract：:Gastric cancer (GC) is a common aggressive malignant tumor with high incidence and mortality worldwide. GC is classified into intestinal and diffuse types according to the histo-morphological features. Because of distinctly different clinico-pathological features, new cancer therapy strategies and in vitro preclinical...

journal_title：Scientific reports

authors： Jang M,Koh I,Lee SJ,Cheong JH,Kim P

更新日期：2017-01-27 00:00:00

abstract：:Monitoring of disease/therapeutic conditions is an important application of circulating tumor DNA (ctDNA). We devised numerical indices, based on ctDNA dynamics, for therapeutic response and disease progression. 52 lung cancer patients subjected to the EGFR-TKI treatment were prospectively collected, and ctDNA levels ...

journal_title：Scientific reports

authors： Kato K,Uchida J,Kukita Y,Kumagai T,Nishino K,Inoue T,Kimura M,Oba S,Imamura F

更新日期：2016-07-06 00:00:00