Evolution of sickle cell disease from a life-threatening disease of children to a chronic disease of adults: The last 40 years.

Abstract:

:Over the past 40 years, public health measures such as universal newborn screening, penicillin prophylaxis, vaccinations, and hydroxyurea therapy have led to an impressive decline in sickle cell disease (SCD)-related childhood mortality and SCD-related morbidity in high-income countries. We remain cautiously optimistic that the next 40 years will be focused on meeting current challenges in SCD by addressing chronic complications of SCD to reduce mortality and improve quality of life in a growing population of adults with SCD in high-income countries, while simultaneously decreasing the disparity of medical care between high and low-income countries.

journal_name

Am J Hematol

authors

Chaturvedi S,DeBaun MR

doi

10.1002/ajh.24235

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

5-14

issue

1

eissn

0361-8609

issn

1096-8652

journal_volume

91

pub_type

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