Abstract：
:Current theories describe learning in terms of cognitive or associative mechanisms. To assess whether cognitive mechanisms interact with automaticity of associative processes we devised a shape-discrimination task in which participants received both explicit instructions and implicit information. Instructions further allowed for the inference that a first event would precede the target. Albeit irrelevant to respond, this event acted as response prime and implicit spatial cue (i.e. it predicted target location). To modulate cognitive involvement, in three experiments we manipulated modality and salience of the spatial cue. Results always showed evidence for a priming effect, confirming that the first stimulus was never ignored. More importantly, although participants failed to consciously recognize the association, responses to spatially cued trials became either slower or faster depending on salience of the first event. These findings provide an empirical demonstration that cognitive and associative learning mechanisms functionally co-exist and interact to regulate behaviour.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Nico D,Daprati Edoi
10.1038/srep16156subject
Has Abstractpub_date
2015-11-04 00:00:00pages
16156issn
2045-2322pii
srep16156journal_volume
5pub_type
杂志文章abstract：:Methylation of DNA CpG sites is a major mechanism of epigenetic gene silencing and plays important roles in cell division, development and carcinogenesis. One of its regulators is the 64-residue C-terminal Transcriptional Repressor Domain (the TRD) of MBD1, which recruits several repressor proteins such as MCAF1, HDAC...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04896
更新日期：2014-05-09 00:00:00
abstract：:In this report, a hand-held impulse-radar breast cancer detector is presented and the detectability of malignant breast tumors is demonstrated in the clinical test at Hiroshima University Hospital, Hiroshima, Japan. The core functional parts of the detector consist of 65-nm technology complementary metal-oxide-semicon...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16617-6
更新日期：2017-11-27 00:00:00
abstract：:Asthma is characterized by airway inflammation, mucus secretion, remodeling and hyperresponsiveness (AHR). Recent research has established the bronchodilatory effect of bitter taste receptor (TAS2R) agonists in various models. Comprehensive pre-clinical studies aimed at establishing effectiveness of TAS2R agonists in ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep46166
更新日期：2017-04-11 00:00:00
abstract：:Little is known regarding the interplays between the mechanical and molecular bases for vein graft restenosis. We elucidated the stenosis initiation using a high-frequency ultrasonic (HFU) echogenicity platform and estimated the endothelium yield stress from von-Mises stress computation to predict the damage locations...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22147
更新日期：2016-02-26 00:00:00
abstract：:Numerous essential metal elements (EMEs) are necessary to maintain the proper function of human body. In this case-control study, we investigated the associations of 11 EMEs [Calcium (Ca), potassium (K), magnesium (Mg), sodium (Na), manganese (Mn), selenium (Se), cobalt (Co), Molybdenum (Mo), copper (Cu), zinc (Zn), a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66496-7
更新日期：2020-07-03 00:00:00
abstract：:Compression of optical pulses to ultrashort pulse widths using methods of nonlinear optics is a well-established technology of modern laser science. Extending these methods to pulses with high peak powers, which become available due to the rapid progress of laser technologies, is, however, limited by the universal phy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36263
更新日期：2017-04-03 00:00:00
abstract：:Multimodal polymeric nanoparticles have many exciting diagnostic and therapeutic applications, yet their uptake and passage by the placenta, and applications in the treatment of pregnancy complications have not been thoroughly investigated. In this work, the maternal-fetal-placental biodistribution of anionic and cati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03128-7
更新日期：2017-06-06 00:00:00
abstract：:The non-protein amino acid β-methylamino-L-alanine (BMAA) is a neurotoxin present in microalgae and shown to accumulate in the food web. BMAA has been linked to the complex neurodegenerative disorder of Guam and to increased incidents sporadic ALS. Two main neurotoxic routes are suggested; an excitotoxic by acting as ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29631
更新日期：2016-07-12 00:00:00
abstract：:Influenza A viruses can infect a wide variety of animal species and, occasionally, humans. Infection occurs through the binding formed by viral surface glycoprotein hemagglutinin and certain types of glycan receptors on host cell membranes. Studies have shown that the α2,3-linked sialic acid motif (SA2,3Gal) in avian,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15778
更新日期：2015-10-28 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25406
更新日期：2016-05-13 00:00:00
abstract：:Drug-induced cholestasis is a leading cause of drug withdrawal. However, the use of primary human hepatocytes (PHHs), the gold standard for predicting cholestasis in vitro, is limited by their high cost and batch-to-batch variability. Mature hepatocyte characteristics have been observed in human induced hepatocytes (h...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38694
更新日期：2016-12-09 00:00:00
abstract：:Anthracnose caused by Colletotrichum is one of the most severe diseases of Hevea brasiliensis. However, research on the diversity and geographical distribution of Colletotrichum remains limited in China. In this study, we investigated the phylogenetic diversity of Colletotrichum isolates associated with symptomatic ti...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28166-7
更新日期：2018-07-11 00:00:00
abstract：:Sirtuin 1 (SIRT1) is involved in both aging and circadian-clock regulation, yet the link between the two processes in relation to SIRT1 function is not clear. Using Sirt1-deficient mice, we found that Sirt1 and Period 2 (Per2) constitute a reciprocal negative regulation loop that plays important roles in modulating he...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28633
更新日期：2016-06-27 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31793
更新日期：2016-08-23 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16698
更新日期：2015-11-18 00:00:00
abstract：:Light damages photosynthetic machinery, primarily photosystem II (PSII), and it results in photoinhibition. A new photodamage model, the two-step photodamage model, suggests that photodamage to PSII initially occurs at the oxygen evolving complex (OEC) by light energy absorbed by manganese and that the PSII reaction c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16363
更新日期：2015-11-12 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53171-9
更新日期：2019-11-19 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36084
更新日期：2016-11-10 00:00:00
abstract：:All grain boundaries are not equal in their predisposition for fracture due to the complex coupling between lattice geometry, interfacial structure, and mechanical properties. The ability to understand these relationships is crucial to engineer materials resilient to grain boundary fracture. Here, a methodology is pre...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08637-z
更新日期：2017-08-21 00:00:00
abstract：:White light generation by mixing red, green, and blue laser diodes (RGB LDs) was demonstrated with Commission International de l'Eclairage coordinates of (0.2928, 0.2981), a correlated color temperature of 8382 K, and a color rendering index of 54.4 to provide a maximal illuminance of 7540 lux. All the white lights ge...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00052-8
更新日期：2017-01-31 00:00:00
abstract：:Broadband on-chip optical frequency combs (OFCs) are important for expanding the functionality of photonic integrated circuits. Here, we demonstrate a huge local optical nonlinearity enhancement using graphene. A waveguide is decorated with graphene by precisely manipulating graphene's area and position. Our approach ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45520
更新日期：2017-04-12 00:00:00
abstract：:Second-harmonic generation (SHG) is the most specific label-free indicator of collagen accumulation in widespread pathologies such as fibrosis, and SHG-based measurements hold important potential for biomedical analyses. However, efficient collagen SHG scoring in histological slides is hampered by the limited depth-of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29863
更新日期：2016-07-20 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-58955-y
更新日期：2020-02-21 00:00:00
abstract：:The present study aimed to evaluate the accuracy and repeatability of morphological contour interpolation (MCI)-based semiautomatic segmentation method for volumetric measurements of bone grafts around dental implants. Three in vitro (one with a cylinder and two with a geometrically complex form) and four ex vivo mode...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71651-1
更新日期：2020-09-10 00:00:00
abstract：:Glomalin-related soil protein (GRSP) is known as an important microbial by-product which is crucial for preserving or accumulating soil organic carbon (SOC). However, the underlying mechanisms are not well understood. In this study, we investigated the chemical structures of GRSP and its relationship with SOC using 13...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02486-6
更新日期：2017-05-24 00:00:00
abstract：:Graphene grown by high temperature molecular beam epitaxy on hexagonal boron nitride (hBN) forms continuous domains with dimensions of order 20 μm, and exhibits moiré patterns with large periodicities, up to ~30 nm, indicating that the layers are highly strained. Topological defects in the moiré patterns are observed ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22440
更新日期：2016-03-01 00:00:00
abstract：:The interaction between the T cell antigen receptor (TCR) and antigenic peptide in complex with major histocompatibility complex (MHC) molecules is a crucial step in T cell activation. The relative contributions of TCR:peptide and TCR:MHC contacts to the overall binding energy remain unclear. This has important implic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35326
更新日期：2016-10-13 00:00:00
abstract：:Though carbon (C): nitrogen (N) stoichiometry has been widely studied in terrestrial ecosystems, little is known about its variation following afforestation. By synthesizing the results of 53 studies, we examined temporal and spatial variation in C: N ratios and in N-C scaling relationships of both the organic and the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19117
更新日期：2016-01-08 00:00:00
abstract：:Organic nanofibers have found various applications in optoelectronic devices. In such devices, exciton diffusion is a major aspect concerning their efficiency. In the case of singlet excitons, Förster transfer is the mechanism responsible for this process. Temperature and morphology are factors known to influence exci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32232-5
更新日期：2018-09-19 00:00:00
abstract：:Three-dimensional integrated circuits (3D ICs) are an attractive replacement for conventional 2D ICs as high-performance, low-power-consumption, and small-footprint microelectronic devices. However, one of the major remaining challenges is the manufacture of high-aspect-ratio through-silicon vias (TSVs), which is a cr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40785
更新日期：2017-01-18 00:00:00
