Subclinical autism spectrum symptoms in pediatric obsessive-compulsive disorder.

Abstract:

:The literature on subclinical autism spectrum (ASD) symptoms in pediatric obsessive-compulsive disorder (OCD) is scarce, and it remains unclear whether ASD symptoms are related to OCD severity. The aims of the present study were to assess the prevalence of ASD symptoms and age and sex differences in children and adolescents with OCD, and to explore the relation between ASD symptoms and OCD severity. This is the largest study of ASD symptoms in an OCD population to date, and the first directly aimed at elucidating sex and age differences in this matter. The study used baseline data from the Nordic Long-term OCD Treatment Study in which parents of 257 children and adolescents with OCD aged 7-17 completed the Autism Spectrum Screening Questionnaire. OCD severity was assessed with the Children's Yale-Brown Obsessive Compulsive Scale. Pediatric OCD patients were found to exhibit elevated rates of ASD symptoms compared to a norm group of school-age children. ASD symptoms were concentrated in a subgroup with a prevalence of 10-17 %. This subgroup was characterized by a male preponderance with a sex ratio of approximately 2.6:1, while children versus adolescents with OCD exhibited similar rates. Autism-specific social and communication difficulties were not related to OCD severity, while restricted repetitive behavior was positively related to OCD severity. The results indicate that clinicians need to be aware of ASD symptoms in children and adolescents with OCD since one out of ten exhibits such symptoms at a clinical sub-threshold.

authors

Arildskov TW,Højgaard DR,Skarphedinsson G,Thomsen PH,Ivarsson T,Weidle B,Melin KH,Hybel KA

doi

10.1007/s00787-015-0782-5

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

711-23

issue

7

eissn

1018-8827

issn

1435-165X

pii

10.1007/s00787-015-0782-5

journal_volume

25

pub_type

杂志文章
  • The association between preschool behavioural problems and internalizing difficulties at age 10-12 years.

    abstract::The aim was to study the association between preschool behavioural problems and emotional symptoms in 10- to 12-year-old children. The study was based on the Aarhus Birth cohort, Denmark, and included 1,336 children. Based on the parent-administered preschool behaviour questionnaire (PBQ), we identified three not mutu...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-010-0128-2

    authors: Slemming K,Sørensen MJ,Thomsen PH,Obel C,Henriksen TB,Linnet KM

    更新日期:2010-10-01 00:00:00

  • The use of the ADI-R as a diagnostic tool in the differential diagnosis of children with infantile autism and children with a receptive language disorder.

    abstract::Children with infantile autism and children with a specific receptive language disorder often show similar behavioural problems, making the differentiation between these two diagnostic categories difficult. The purpose of this study is to evaluate the usefulness of parental information in the differential diagnosis of...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s007870170014

    authors: Mildenberger K,Sitter S,Noterdaeme M,Amorosa H

    更新日期:2001-12-01 00:00:00

  • Heterogeneity in the pharmacodynamics of two long-acting methylphenidate formulations for children with attention deficit/hyperactivity disorder. A growth mixture modelling analysis.

    abstract:OBJECTIVES:To use growth mixture modelling (GMM) to identify subgroups of children with attention deficit hyperactive disorder (ADHD) who have different pharmacodynamic profiles in response to extended release methylphenidate as assessed in a laboratory classroom setting. METHODS:GMM analysis was performed on data fro...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-007-0667-3

    authors: Sonuga-Barke EJ,Van Lier P,Swanson JM,Coghill D,Wigal S,Vandenberghe M,Hatch S

    更新日期:2008-06-01 00:00:00

  • Child mental health and resilience in the context of socioeconomic disadvantage: results from the Born in Bradford cohort study.

    abstract::Socioeconomic disadvantage has been linked to mental health difficulties in children and adolescents, although many children appear to do well despite exposure to financial adversity in childhood. Our study looked at the effects of family financial difficulty on children's mental health outcomes (n = 636) at 4-5 years...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00787-019-01348-y

    authors: Kirby N,Wright B,Allgar V

    更新日期:2020-04-01 00:00:00

  • Resveratrol adjunct to methylphenidate improves symptoms of attention-deficit/hyperactivity disorder: a randomized, double-blinded, placebo-controlled clinical trial.

    abstract::Current pharmacological approaches have failed to provide complete remission for patients with Attention-Deficit/Hyperactivity Disorder (ADHD). This study aimed to evaluate the efficacy and tolerability of resveratrol (that have been shown to have antioxidative, anti-inflammatory, and anti-apoptotic effects) as an adj...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-020-01562-z

    authors: Rafeiy-Torghabeh M,Ashraf-Ganjouei A,Moradi K,Bagheri S,Mohammadi MR,Akhondzadeh S

    更新日期:2020-05-24 00:00:00

  • Suicidality in clinic-referred transgender adolescents.

    abstract::Gender and sexually diverse adolescents have been reported to be at an elevated risk for suicidal thoughts and behaviors. For transgender adolescents, there has been variation in source of ascertainment and how suicidality was measured, including the time-frame (e.g., past 6 months, lifetime). In studies of clinic-ref...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-020-01663-9

    authors: de Graaf NM,Steensma TD,Carmichael P,VanderLaan DP,Aitken M,Cohen-Kettenis PT,de Vries ALC,Kreukels BPC,Wasserman L,Wood H,Zucker KJ

    更新日期:2020-11-09 00:00:00

  • Associations between maternal closeness, suicidal ideation, and risk behaviors in Cape Town.

    abstract::Health compromising behaviors, such as smoking and other risk behaviors tend to co-occur, and contribute to the leading causes of preventable death, disease, and disability among adolescents and young adults worldwide. The present study assesses a model of the direct and indirect effects of maternal closeness with sui...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-008-0718-4

    authors: Gilreath TD,King G,Graham JW,Flisher AJ,Lombard C

    更新日期:2009-03-01 00:00:00

  • Neuro-physiological correlates of sluggish cognitive tempo (SCT) symptoms in school-aged children.

    abstract::This study was the first to examine the relationship between neurophysiological abnormalities and symptoms of sluggish cognitive tempo (SCT) in children. Thirty children aged 6-12 years were recruited. Their heart rate variability (HRV) was measured under resting and warning signal conditions. At rest, the children's ...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-019-01353-1

    authors: Yung TWK,Lai CYY,Chan JYC,Ng SSM,Chan CCH

    更新日期:2020-03-01 00:00:00

  • Premorbid adjustment and remission of positive symptoms in first-episode psychosis.

    abstract::The impact of premorbid social and intellectual functioning in childhood and early adolescence on the developmental course of schizophrenia is not sufficiently understood. In a retrospective case study (93 consecutive in-patients, 43 males and 50 females) of first-episode psychosis occurring in adolescence, the relati...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/BF00539928

    authors: Amminger GP,Resch F,Mutschlechner R,Friedrich MH,Ernst E

    更新日期:1997-12-01 00:00:00

  • Refugee children's sandplay narratives in immigration detention in Canada.

    abstract::Asylum seeking children arriving in Canada regularly face incarceration in medium-security-style immigration detention centres. Research demonstrates the human cost of detaining migrant children and families and the psychiatric burden linked with such imprisonment. This study aims to understand the lived experiences o...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-017-1012-0

    authors: Kronick R,Rousseau C,Cleveland J

    更新日期:2018-04-01 00:00:00

  • Using DSM diagnoses for clinical, research, and administrative purposes.

    abstract::DSM data are often used to build statistics on the types of patients to whom mental health services are offered. These statistics are normally based on broad categories that cluster finer subcategories for specific diagnoses. These broad categories can be built in a number of ways. The purpose of this study is to dete...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s007870070028

    authors: van Yperen TA,van Engeland H,Cohen-Kettenis PT,Rispens J

    更新日期:2000-12-01 00:00:00

  • Autistic spectrum disorders in childhood epilepsy surgery candidates.

    abstract::One third of children with autistic spectrum disorders (or pervasive developmental disorders) enter that state by regression from a more normal prior development at the onset of epilepsy or epileptiform abnormality in the electroencephalogram. In a very small proportion structural lesions of the temporal lobes are dis...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s007870050128

    authors: Taylor DC,Neville BG,Cross JH

    更新日期:1999-09-01 00:00:00

  • The role of genetic and environmental factors in covariation between anxiety and anger in childhood.

    abstract::Higher levels of anger expression, as well as lower levels of anger control, have been reported for adults with anxiety disorders compared to individuals without anxiety disorders. Different to the research on adults, very few studies examined the relationship between anxiety and anger in childhood. In our study, we i...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-020-01543-2

    authors: Scaini S,Centorame G,Lissandrello F,Sardella S,Stazi MA,Fagnani C,Brombin C,Battaglia M

    更新日期:2020-05-07 00:00:00

  • Multi-rater developmental trajectories of hyperactivity-impulsivity and inattention symptoms from 1.5 to 17 years: a population-based birth cohort study.

    abstract::The developmental course of hyperactivity-impulsivity and inattention symptoms from infancy to adolescence has not been documented in a population sample. The aim of this study was to describe the developmental course of hyperactivity-impulsivity and inattention symptoms from 1.5 to 17 years using multiple informants,...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-018-1258-1

    authors: Vergunst F,Tremblay RE,Galera C,Nagin D,Vitaro F,Boivin M,Côté SM

    更新日期:2019-07-01 00:00:00

  • Influence of assessment instrument on ADHD diagnosis.

    abstract::We compared four instruments commonly used to screen for and diagnose Attention-Deficit/Hyperactivity Disorder (ADHD) in children. The Bergen Child Study included a DSM-IV ADHD symptom list and the Strengths and Difficulties Questionnaire (SDQ) as screen in Phase one. Phase two included the parent Development and Well...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-013-0442-6

    authors: Posserud MB,Ullebø AK,Plessen KJ,Stormark KM,Gillberg C,Lundervold AJ

    更新日期:2014-04-01 00:00:00

  • Cooperative parent-mediated therapy for Italian preschool children with autism spectrum disorder: a randomized controlled trial.

    abstract::Parent-mediated intervention is widely used for pre-schoolers with autism spectrum disorder (ASD). Previous studies indicate small-to-moderate effects on social communication skills, but with a wide heterogeneity that requires further research. In this randomized controlled trial (RCT), cooperative parent-mediated the...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00787-019-01395-5

    authors: Valeri G,Casula L,Menghini D,Amendola FA,Napoli E,Pasqualetti P,Vicari S

    更新日期:2020-07-01 00:00:00

  • The outcome of adolescent eating disorders: findings from an international collaborative study.

    abstract::Within the International Collaborative Outcome Study of Eating Disorders in Adolescence (ICOSEDA) we studied the clinical features, treatment, and outcome in consecutive cohorts of adolescent patients at five sites in former West Berlin and East Berlin, Zurich, Sofia and Bucharest. A total of N = 242 patients were fol...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00787-003-1112-x

    authors: Steinhausen HC,Boyadjieva S,Griogoroiu-Serbanescu M,Neumärker KJ

    更新日期:2003-01-01 00:00:00

  • Reliability and diagnostic efficiency of the abbreviated-diagnostic interview for borderlines in an adolescent clinical population.

    abstract::Examine the reliability as well as the concurrent validity and diagnostic efficiency of the Abbreviated version of the diagnostic interview for borderlines revised (Ab-DIB) as a screening measure of borderline psychopathology in an adolescent clinical population. The Ab-DIB is a DIB-R-derived self-report covering the ...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-009-0015-x

    authors: Guilé JM,Greenfield B,Berthiaume C,Chapdelaine C,Bergeron L

    更新日期:2009-09-01 00:00:00

  • Mental and somatic health in a non-clinical sample 10 years after a diagnosis of encopresis.

    abstract::The aim of this study was to assess the relation between the diagnosis of encopresis at 8 and 10 years of age, and mental and somatic health 10 years later. The importance of type of encopresis (primary or secondary) at 8 years was also studied. Subjects were a non-clinical encopretic sample (N=73) and control subject...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-005-0495-2

    authors: Hultén I,Jonsson J,Jonsson CO

    更新日期:2005-12-01 00:00:00

  • Juvenile firesetting in Italy: relationship to aggression, psychopathology, personality, self-efficacy, and school functioning.

    abstract::Despite the fact that juvenile fire involvement is associated with significant injuries and is highly correlated with diverse maladjustment characteristics, firesetting has never been empirically evaluated in Italy. Participants included 567 youth between 11 and 18 years of age. This investigation attempted to address...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-007-0664-6

    authors: Del Bove G,Caprara GV,Pastorelli C,Paciello M

    更新日期:2008-06-01 00:00:00

  • Associations between attention-deficit/hyperactivity disorder and autoimmune diseases are modified by sex: a population-based cross-sectional study.

    abstract::Several studies have demonstrated associations between neuropsychiatric disorders, such as attention-deficit/hyperactivity disorder (ADHD), and the immune system, including autoimmune diseases. Since ADHD and many autoimmune diseases show sex-specific properties, such associations may also differ by sex. Using Norwegi...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-017-1056-1

    authors: Hegvik TA,Instanes JT,Haavik J,Klungsøyr K,Engeland A

    更新日期:2018-05-01 00:00:00

  • Service-level variation, patient-level factors, and treatment outcome in those seen by child mental health services.

    abstract::Service comparison is a policy priority but is not without controversy. This paper aims to investigate the amount of service-level variation in outcomes in child mental health, whether it differed when examining outcomes unadjusted vs. adjusted for expected change over time, and which patient-level characteristics wer...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-016-0939-x

    authors: Edbrooke-Childs J,Macdougall A,Hayes D,Jacob J,Wolpert M,Deighton J

    更新日期:2017-06-01 00:00:00

  • Psychosis following acute Sydenham's chorea.

    abstract::Sydenham's chorea (SC) is characterized by motor, mainly choreic involuntary movements, and psychiatric symptoms, including anxiety, depression, obsessive-compulsive and attention-deficit/hyperactivity disorders. Symptoms of SC may be considered as the result of basal ganglia dysfunction determined by autoimmune mecha...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-006-0566-z

    authors: Teixeira AL Jr,Maia DP,Cardoso F

    更新日期:2007-02-01 00:00:00

  • Does oligoantigenic diet influence hyperactive/conduct-disordered children--a controlled trial.

    abstract::A crossover 'placebo'-controlled, double-blind design was used to examine the effectiveness of an oligoantigenic diet in 49 children with hyperactive/disruptive behavior disorder. Effects of diet were compared with those yielded by stimulant medication (methylphenidate). The study was conducted in an inpatient unit at...

    journal_title:European child & adolescent psychiatry

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF00566671

    authors: Schmidt MH,Möcks P,Lay B,Eisert HG,Fojkar R,Fritz-Sigmund D,Marcus A,Musaeus B

    更新日期:1997-06-01 00:00:00

  • Non-stimulant treatments for ADHD.

    abstract::We reviewed the literature of medication trials in ADHD to evaluate the scope of the available non-stimulant treatments. A variety of compounds with a common noradrenergic/ dopaminergic activity have shown documented anti-ADHD activity. There is a substantial body of literature documenting the efficacy of tricyclic an...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,评审

    doi:10.1007/s007870070019

    authors: Biederman J,Spencer T

    更新日期:2000-01-01 00:00:00

  • When does the Autism Spectrum Screening Questionnaire (ASSQ) predict autism spectrum disorders in primary school-aged children?

    abstract::The aims of this study were, firstly, to study the association between parents' and teachers' ratings for the Finnish version of the Autism Spectrum Screening Questionnaire (ASSQ), secondly, to find out whether the original cut-off scores of the ASSQ identify primary school-aged children with Asperger syndrome (AS) or...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-009-0044-5

    authors: Mattila ML,Jussila K,Kuusikko S,Kielinen M,Linna SL,Ebeling H,Bloigu R,Joskitt L,Pauls D,Moilanen I

    更新日期:2009-08-01 00:00:00

  • Antipsychotics in early onset Schizophrenia: Systematic review and meta-analysis.

    abstract:BACKGROUND:To develop an evidence base for using antipsychotic medications for schizophrenia in children and adolescents. METHOD:Data sources were identified in PsychINFO (1872-2003), MEDLINE (1966-2003), and articles in reference lists. Study selection criteria: (1) treatment with antipsychotics; (2) ages were betwee...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00787-005-0515-2

    authors: Armenteros JL,Davies M

    更新日期:2006-03-01 00:00:00

  • Emotional valence detection in adolescents with oppositional defiant disorder/conduct disorder or autism spectrum disorder.

    abstract::Oppositional defiant disorder, conduct disorder (ODD/CD), and autism spectrum disorder (ASD) share poor empathic functioning and have been associated with impaired emotional processing. However, no previous studies directly compared similarities and differences in these processes for the two disorders. A two-choice em...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章

    doi:10.1007/s00787-019-01282-z

    authors: Herpers PCM,Bakker-Huvenaars MJ,Greven CU,Wiegers EC,Nijhof KS,Baanders AN,Buitelaar JK,Rommelse NNJ

    更新日期:2019-07-01 00:00:00

  • A genome-wide search strategy for identifying quantitative trait loci involved in reading and spelling disability (developmental dyslexia).

    abstract::Family and twin studies of developmental dyslexia have consistently shown that there is a significant heritable component for this disorder. However, any genetic basis for the trait is likely to be complex, involving reduced penetrance, phenocopy, heterogeneity and oligogenic inheritance. This complexity results in re...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,评审

    doi:10.1007/pl00010694

    authors: Fisher SE,Stein JF,Monaco AP

    更新日期:1999-01-01 00:00:00

  • Conduct disorder in adolescent females: current state of research and study design of the FemNAT-CD consortium.

    abstract::Conduct disorder (CD) is a common and highly impairing psychiatric disorder of childhood and adolescence that frequently leads to poor physical and mental health outcomes in adulthood. The prevalence of CD is substantially higher in males than females, and partly due to this, most research on this condition has used a...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,评审

    doi:10.1007/s00787-018-1172-6

    authors: Freitag CM,Konrad K,Stadler C,De Brito SA,Popma A,Herpertz SC,Herpertz-Dahlmann B,Neumann I,Kieser M,Chiocchetti AG,Schwenck C,Fairchild G

    更新日期:2018-09-01 00:00:00