Impact of Polypharmacy on Adherence to Evidence-Based Medication in Patients who Underwent Percutaneous Coronary Intervention.

abstract：BACKGROUND:Atherosclerosis is a multifactorial inflammatory disease of the cardiovascular system. It has been suggested that periodontitis, an infectious disease of oral cavity caused by gramnegative anaerobic bacteria, could be linked to atherosclerosis. OBJECTIVE:The objective of this systematic review was to assess...

journal_title：Current vascular pharmacology

authors： Almeida APCPSC,Fagundes NCF,Maia LC,Lima RR

更新日期：2018-01-01 00:00:00

abstract：:Nowadays long-term outcome of heart transplantation is limited by a peculiar type of coronary atherosclerosis, known as cardiac allograft vasculopathy (CAV). Although the exact pathogenesis of CAV remains unclear, emerging evidence indicates that the endothelium plays a significant role in the onset and progression of...

journal_title：Current vascular pharmacology

authors： Osto E,Tona F,De Bon E,Iliceto S,Cella G

更新日期：2010-03-01 00:00:00

abstract：:Revascularization procedures used for the treatment of cardiovascular disease can be associated with restenosis, although drug-coated stents have greatly reduced this complication. Both type 2 diabetes (T2DM) and metabolic syndrome (MetS) are associated with a high risk for atherosclerosis and restenosis. Insulin resi...

journal_title：Current vascular pharmacology

authors： Breen DM,Giacca A

更新日期：2011-05-01 00:00:00

abstract：:In end-stage renal disease patients, the leading causes of mortality are of cardiovascular (CV) origin. The underlying mechanisms are complex, given that sudden heart failure is more common than acute myocardial infarction. A contributing role of oxidative stress is postulated, which is increased even at early stages ...

journal_title：Current vascular pharmacology

authors： Roumeliotis S,Roumeliotis A,Gorny X,Mertens PR

更新日期：2021-01-01 00:00:00

abstract：:Cardiovascular disease (CVD) is among the most major causes of morbidity and mortality worldwide. Great progress has been made in the management of CVD which has been influenced by the use of experimental animal models. These models provided information at cellular and molecular levels and allowed the development of t...

journal_title：Current vascular pharmacology

authors： Haidara MA,Assiri AS,Yassin HZ,Ammar HI,Obradovic MM,Isenovic ER

更新日期：2015-01-01 00:00:00

abstract：:Recent updates in the field of echocardiography have resulted in improvements in both image quality and techniques allowing echocardiography to maintain its position as the primary non-invasive imaging modality. In particular, the development of new ultrasound contrast agents and imaging techniques have now made possi...

journal_title：Current vascular pharmacology

authors： Dwivedi G,Hayat SA,Janardhanan R,Senior R

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) affects a large proportion of the general population. The disease ranges from simple steatosis, to non-alcoholic steatohepatitis (NASH), cirrhosis and even hepatocellular carcinoma. Several drugs are used in daily clinical practice to manage the disease. However, dat...

journal_title：Current vascular pharmacology

authors： Imprialos K,Stavropoulos K,Bouloukou S,Kerpiniotis G,Karagiannis A,Doumas M

更新日期：2018-01-01 00:00:00

abstract：:This review provides evidence that antenatal hypoxia, which represents a significant and worldwide problem, causes prenatal programming of the lung. A general overview of lung development is provided along with some background regarding transcriptional and signaling systems of the lung. The review illustrates that ant...

journal_title：Current vascular pharmacology

authors： Papamatheakis DG,Blood AB,Kim JH,Wilson SM

更新日期：2013-09-01 00:00:00

abstract：:Several lines of evidence suggest a detrimental effect of aldosterone excess on the development of metabolic alterations. Glucose metabolism derangements due to aldosterone action are frequently observed not only in patients with primary aldosteronism but also in patients with obesity. A contribution to the hyperaldos...

journal_title：Current vascular pharmacology

authors： Ronconi V,Turchi F,Appolloni G,di Tizio V,Boscaro M,Giacchetti G

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:Diabetes mellitus (DM) is one of the most common diseases worldwide. Its adverse effects on several body organs, have made treatment of DM a priority. One of the most serious complications of DM is diabetic nephropathy (DN). OBJECTIVE:The aim of this review is to critically discuss available data on the p...

journal_title：Current vascular pharmacology

authors： Papademetriou V,Alataki S,Stavropoulos K,Papadopoulos C,Bakogiannis K,Tsioufis K

更新日期：2020-01-01 00:00:00

abstract：:Chronic kidney disease (CKD), and particularly kidney failure, is associated with accelerated atherosclerosis and approximately a 20-fold increased risk of cardiovascular death. The majority of these patients die from complications directly attributed to atherosclerosis and their life expectancy is decreased. Establis...

journal_title：Current vascular pharmacology

authors： Efstratiadis G,Tziomalos K,Mikhailidis DP,Athyros VG,Hatzitolios A

更新日期：2008-04-01 00:00:00

abstract：:A number of epidemiological studies have shown that diets rich in plant-derived phenolic compounds reduce the risk of coronary heart disease. The chronic antioxidant and hypolipidemic activities of these compounds have important roles in prevention of lipoprotein oxidation and atherosclerotic lesion development. In re...

journal_title：Current vascular pharmacology

authors： Jiang F,Dusting GJ

更新日期：2003-06-01 00:00:00

abstract：:Postprandial hypertriglyceridaemia, defined as an increase in plasma triglyceride-containing lipoproteins following a fat meal, is a potential risk predictor of atherosclerotic cardiovascular disease and other chronic diseases. Several non-modifiable factors (genetics, age, sex and menopausal status) and lifestyle fac...

journal_title：Current vascular pharmacology

authors： Kolovou GD,Watts GF,Mikhailidis DP,Pérez-Martínez P,Mora S,Bilianou H,Panotopoulos G,Katsiki N,Ooi TC,Lopez-Miranda J,Tybjærg-Hansen A,Tentolouris N,Nordestgaard BG

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Volatile Anaesthetics (VA) are commonly used worldwide for induction and/or maintenance of general anaesthesia. They act in the central nervous system to reduce sensation and motor response during surgical and invasive diagnostic procedures. VAs also have some non-anaesthetic properties in the brain when adm...

journal_title：Current vascular pharmacology

authors： Krzych LJ,Szczepanska AJ

更新日期：2018-01-01 00:00:00

abstract：:Inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis (UC) are idiopathic, intestinal and systemic inflammatory disorders which are immunologically mediated with the activation of plasma proteolytic cascades. The activation of coagulation in IBD is related to the activity and colonic extension of t...

journal_title：Current vascular pharmacology

authors： Stadnicki A

更新日期：2012-09-01 00:00:00

abstract：:This review considers drug combinations and newer treatment strategies for patients with severe hypertriglyceridemia. Hypertriglyceridemia is associated with an atherogenic metabolic profile and in most studies with increased cardiovascular disease risk. Patients with severe hypertriglyceridemia also have increased in...

journal_title：Current vascular pharmacology

authors： Filippatos TD,Elisaf MS

更新日期：2014-01-01 00:00:00

abstract：:High density lipoprotein (HDL) is recognized as the major negative risk factor of cardiovascular disease and number of anti-atherogenic functions has been ascribed to HDL. HDL is an assembly of a neutral lipid core and an outer shell consisting of polar lipids and proteins. It has been defined many different ways base...

journal_title：Current vascular pharmacology

authors： Vaisar T

更新日期：2012-07-01 00:00:00

abstract：:Normal pregnancy is associated with increased insulin resistance as a metabolic adaptation to the nutritional demands of the placenta and fetus, and this is amplified in obese mothers. Insulin resistance is normally compensated for by an adaptive increase in pancreatic β-cell mass together with enhanced glucose-stimul...

journal_title：Current vascular pharmacology

authors： Szlapinski SK,Hill DJ

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The association between Paget's disease of bone (PDB) and increased cardiovascular (CV) risk has been suggested, but the literature is conflicting. OBJECTIVE:Our study aimed to evaluate two markers of CV risk [common carotid artery intima-media thickness (cIMT) and the aortic pulse wave velocity (PWV)] in p...

journal_title：Current vascular pharmacology

authors： Gaudio A,Zanoli L,Xourafa A,Rapisarda R,Catalano A,Signorelli SS,Castellino P

更新日期：2020-06-09 00:00:00

abstract：:Atherosclerosis (also known as arteriosclerotic vascular disease) is a chronic inflammatory disease of the arterial wall, characterized by the formation of lipid-laden lesions. The activation of endothelial cells at atherosclerotic lesion-prone sites in the arterial tree results in the up-regulation of cell adhesion m...

journal_title：Current vascular pharmacology

authors： Araldi E,Chamorro-Jorganes A,van Solingen C,Fernández-Hernando C,Suárez Y

更新日期：2013-05-13 00:00:00

abstract：:Fifteen years after its discovery, NO has fully reached an established position in physiology, medicine and therapeutics. It is difficult to find a biological function or a pathological condition where NO does not play a relevant role. Discoveries in the NO field have historically evolved from cardiovascular research,...

journal_title：Current vascular pharmacology

authors： Llorens S,Nava E

更新日期：2003-10-01 00:00:00

abstract：:This paper provides an overview of the pathogenesis, presentation and diagnosis of clopidogrel hypersensitivity. The majority of clopidogrel hypersensitivity cases are due to a T cell mediated Gell and Coombs Type IV reaction. History, histology, and patch testing have shown consistency with a T cell mediated mechanis...

journal_title：Current vascular pharmacology

authors： Ford MK,Cohn JR

更新日期：2019-01-01 00:00:00

abstract：:The renin-angiotensin system (RAS) plays an essential role in fluid and electrolyte homeostasis and the regulation of vascular tone; however, dysregulation and over-activation of the RAS lead to the pathogenesis of various cardiovascular diseases. The RAS is closely associated with NADPH oxidase, a major enzymatic sou...

journal_title：Current vascular pharmacology

authors： Honjo T,Yamaoka-Tojo M,Inoue N

更新日期：2011-03-01 00:00:00

abstract：:Cell-based therapies are a novel approach for regeneration of microvasculature. We have shown that administration of CD34-positive cells, the rich cell fraction of endothelial progenitor cells, after stroke induces angiogenesis that results in enhanced endogenous neurogenesis and functional recovery in a murine model....

journal_title：Current vascular pharmacology

authors： Uemura M,Kasahara Y,Nagatsuka K,Taguchi A

更新日期：2012-05-01 00:00:00

abstract：:Chronic venous disease (CVeD) is a debilitating condition that affects millions of individuals worldwide. The condition can result in varicose veins, or advance to severe skin changes and venous ulceration. The fundamental basis for CVeD is inflammation within the venous circulation and that it is subjected to increas...

journal_title：Current vascular pharmacology

authors： Mannello F,Ligi D,Canale M,Raffetto JD

更新日期：2014-01-01 00:00:00

abstract：: ...

journal_title：Current vascular pharmacology

authors： Cortese F

更新日期：2019-01-01 00:00:00

abstract：:Urocortin comprises a group of endogenously produced peptide hormones that belong to the corticotropinreleasing factor (CRF) family with promising future as potential drugs for the treatment of heart disease. Members of the urocortin family are known to act as potent regulators of cardiac and vascular functions, throu...

journal_title：Current vascular pharmacology

authors： Díaz I,Smani T

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Single-pill fixed dose combination (FDC) therapies are widely used in the treatment of arterial hypertension. OBJECTIVE:This pilot study aimed to evaluate the effects of a FDC therapy combined with therapeutic drug monitoring (TDM) on blood pressure (BP) in patients with treatment resistant hypertension. M...

journal_title：Current vascular pharmacology

authors： Kreutz R,Scholze J,Douros A

更新日期：2018-01-26 00:00:00

abstract：BACKGROUND:In the era of dual antiplatelet therapy of aspirin and clopidogrel and systematic stent implantation, Glycoprotein IIb/IIIa Inhibitors (GPI), including abciximab, eptifibatide and tirofiban, proved beneficial in improving early outcome of Percutaneous Coronary Intervention (PCI), especially in higher risk cl...

journal_title：Current vascular pharmacology

authors： Rubboli A,Patti G

更新日期：2018-01-01 00:00:00

abstract：:Several cellular and molecular mechanisms have been implicated in the development of myocardial dysfunction and low cardiac output in pediatric patients undergoing heart surgery. Ischemia- reperfusion injury with alterations in calcium homeostasis as well as mitochondrial function has been strongly related to myocyte ...

journal_title：Current vascular pharmacology

authors： Bautista-Hernandez V,Karamanlidis G,McCully JD,Del Nido PJ

更新日期：2016-01-01 00:00:00