Megaesophagus associated with Myasthenia Gravis: a rare condition in humans.


:We present the case of a 79 year-old patient with megaesophagus and aphagia, who required percutaneous endoscopic gastrostomy (PEG) feeding. Megaesophagus was considered the sole cause of aphagia by the referring secondary hospital. Solid state sensor videofluoromanometry (VFM) showed a substantial decrease in manometric values within the hypopharynx along with good relaxation of the upper-esophageal sphincter (UES). This led to electromyography (EMG), which showed features compatible with the diagnosis of Myasthenia Gravis (MG). The diagnosis of MG was confirmed by an intravenous injection of edrophonium chloride, performed under VFM monitoring. The co-existence of MG and megaesophagus rarely occurs in humans; although, most small animals, such as dogs, cats, and rodents, present with megaesophagus as an initial symptom of MG.






Desuter G,Van Parijs V,Gardiner Q


Has Abstract


2015-01-01 00:00:00












  • Prevalence and Associated Factors of Depressive Disorder in Caregivers of Individuals With Parkinson Disease.

    abstract:OBJECTIVE:Parkinson disease (PD) is a debilitating neurodegenerative disease. Caring for an individual with PD can have a variety of negative physical and psychological effects on caregivers which may challenge their ability to continue in their caretaking role. The aim of this study was to assess the prevalence and as...

    journal_title:Journal of geriatric psychiatry and neurology

    pub_type: 杂志文章


    authors: Lee Y,Chiou YJ,Hung CF,Chang YY,Chen YF,Lin TK,Wang LJ

    更新日期:2020-06-26 00:00:00

  • Prevalence and types of Campylobacter on poultry farms and in their direct environment.

    abstract::To study whether broiler and layer farms contribute to the environmental Campylobacter load, environmental matrices at or close to farms, and caecal material from chickens, were examined. Similarity between Campylobacter from poultry and environment was tested based on species identification and Multilocus Sequence Ty...

    journal_title:Journal of water and health

    pub_type: 杂志文章


    authors: Schets FM,Jacobs-Reitsma WF,van der Plaats RQJ,Heer LK,van Hoek AHAM,Hamidjaja RA,de Roda Husman AM,Blaak H

    更新日期:2017-10-01 00:00:00

  • Purification and partial characterization of a fructose-binding lectin from the leaves of Euphorbia helioscopia.

    abstract::A lectin was purified from leaves of Euphorbia helioscopia, by a combination of ion-exchange and gel filtration chromatography. On ion exchange using a DEAE- cellulose column in 0.2 M phosphate buffer, pH 7.2, the bound protein was eluted with a linear sodium chloride gradient of 0.1 M to 0.5 M. Further purification o...

    journal_title:Pakistan journal of pharmaceutical sciences

    pub_type: 杂志文章


    authors: Rafiq S,Qadir S,Wani IH,Ganie SA,Masood A,Hamid R

    更新日期:2014-11-01 00:00:00

  • Chronic cyclosporin-induced nephropathy.

    abstract:AIMS:There is still no consensus about the prognostic influence of chronic nephropathy induced by low-dose maintenance therapy with cyclosporin. Our aim was to investigate the prognostic effect of cyclosporin nephropathy in Japanese renal transplant recipients. MATERIAL:We retrospectively investigated the clinical rec...

    journal_title:Clinical nephrology

    pub_type: 杂志文章


    authors: Takahara S,Ota K,Takahashi K,Uchida K,Morozumi K,Wang JD,Kyo M,Japanese Cyclosporin Kidney Transplant Study Group.

    更新日期:2001-01-01 00:00:00

  • Abdominoplasty and gluteoplasty after massive weight loss: an all-in-one technique.

    abstract:INTRODUCTION:Patients requesting body-contouring surgery after massive weight loss often present with abdominal and lumbar skin excess as well as gluteal ptosis and loss of gluteal projection. In order to restore gluteal projection a circular abdominoplasty in combination with an autologous gluteal augmentation (all-in...

    journal_title:Acta chirurgica Belgica

    pub_type: 杂志文章


    authors: Colebunders B,Van Landuyt K

    更新日期:2017-04-01 00:00:00

  • Medical aspects of obesity.

    abstract::Obesity poses a serious health hazard and its treatment is often disappointing. Major advances have been made during recent years in the understanding of body weight regulation, with the discovery of leptin, a protein produced by adipocytes and acting on the central nervous system to reduce food intake, and that of be...

    journal_title:Acta chirurgica Belgica

    pub_type: 杂志文章,评审


    authors: Scheen AJ,Luyckx FH

    更新日期:1999-05-01 00:00:00

  • Imbalance between Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Promotes Invasion and Metastasis of Head and Neck Squamous Cell Carcinoma.

    abstract:BACKGROUND:The balance between collagenolysis and its inhibition is critical during extracellular matrix remodeling in head and neck squamous cell carcinoma (HNSCC). An imbalance between matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) plays a critical role in the development of tumor cell invasion ...

    journal_title:Clinical laboratory

    pub_type: 杂志文章


    authors: Stanciu AE,Zamfir-Chiru-Anton A,Stanciu MM,Popescu CR,Gheorghe DC

    更新日期:2017-10-01 00:00:00

  • [Alzheimer's disease and human memory].

    abstract::Memory disorders observed in Alzheimer's disease gave rise, from the eighties, to a detailed analysis into the framework of cognitive neuropsychology which aimed at describing the deficits of very specific processes. Beyond their clinical interest, these studies contributed to the modelisation of human memory thanks t...

    journal_title:Revue neurologique

    pub_type: 杂志文章,评审


    authors: Eustache F,Giffard B,Rauchs G,Chételat G,Piolino P,Desgranges B

    更新日期:2006-10-01 00:00:00

  • Purification of human hemopoietic stem cells for transplantation in Thailand.

    abstract::Stem cell transplantation (SCT) has become the therapy of choice for many hematologic and immunologic disorders. At present, only 25% of patients have suitable HLA-identical donors. In an attempt to increase the donor pool for SCT in Thailand and Southeast Asia, we developed a program whereby parents and mismatched si...

    journal_title:Asian Pacific journal of allergy and immunology

    pub_type: 杂志文章


    authors: Udomsakdi-Auewarakul C,U-pratya Y,Chongkolwatana V,Tanphaichitr VS,Pattanapanyasat K,Issaragrisil S

    更新日期:2000-06-01 00:00:00

  • Maxillary hyperplasia and hyperostosis cranialis: a rare manifestation of renal osteodystrophy in a patient with hyperparathyroidism secondary to chronic renal failure.

    abstract::This case report describes a 21-year-old female patient with a complex medical condition of end-stage chronic renal failure and secondary hyperparathyroidism presenting with a history of gradual enlargement of the facial bones over a period of one year. The facial enlargement primarily involves the maxilla causing a b...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Bakathir AA,Margasahayam MV,Al-Ismaily MI

    更新日期:2008-12-01 00:00:00

  • Stem cells, stress, metabolism and cancer: a drama in two Octs.

    abstract::It is a classic story of two related transcription factors. Oct4 is a potent regulator of pluripotency during early mammalian embryonic development, and is notable for its ability to convert adult somatic cells to pluripotency. The widely expressed Oct1 protein shares significant homology with Oct4, binds to the same ...

    journal_title:Trends in biochemical sciences

    pub_type: 杂志文章,评审


    authors: Kang J,Shakya A,Tantin D

    更新日期:2009-10-01 00:00:00

  • Neuropathic arthrogryposis multiplex congenita and intrauterine ischemia of anterior horn cells: a hypothesis.

    abstract::Three patients with multiple articular deformities due to arthrogryposis multiplex congenita (AMC) are presented. All had severe thalamic and tegmental degenerations with glial scars and shrunken ferruginated neurons; one had also unilateral porencephaly and polymicrogyri. The character and the pattern of the lesions ...

    journal_title:Clinical neuropathology

    pub_type: 杂志文章


    authors: Horoupian DS,Yoon JJ

    更新日期:1988-11-01 00:00:00

  • The karyotypes of two bark-lice species (Psocoptera, Psocomorpha, Amphipsocidae): the first description of the neo-XY sex chromosome system in Psocoptera.

    abstract::Karyotypes of two bark-lice species Amphipsocus japonicus End. and Dasypsocus japonicus End. (Amphipsocidae, Psocomorpha, Psocoptera) were studied for the first time. D. japonicus displayed 2n = 16 (14 + XX/X0). The XX/X0 sex chromosome system observed in this species is characteristic of the order Psocoptera. A. japo...

    journal_title:Folia biologica

    pub_type: 杂志文章


    authors: Golub NV,Nokkala S

    更新日期:2001-01-01 00:00:00

  • Added Sugars Intake among US Infants and Toddlers.

    abstract:BACKGROUND:Limited information is available on added sugars consumption in US infants and toddlers. OBJECTIVES:To present national estimates of added sugars intake among US infants and toddlers by sociodemographic characteristics, to identify top sources of added sugars, and to examine trends in added sugars intake. ...

    journal_title:Journal of the Academy of Nutrition and Dietetics

    pub_type: 杂志文章


    authors: Herrick KA,Fryar CD,Hamner HC,Park S,Ogden CL

    更新日期:2020-01-01 00:00:00

  • Salmonellae in gulls and other free-living birds in the Czech Republic.

    abstract::Cloacal swabs, collected from 756 wild synanthropic and exoanthropic birds of 57 species in the Czech Republic, yielded 32 strains of Salmonella typhimurium [phage types (PT) 141, 104 and 41], six isolates of S. enteritidis (PT 8, 4 and 6e), and one each of S. panama and S. anatum. Except for one S. enteritidis isolat...

    journal_title:Central European journal of public health

    pub_type: 杂志文章


    authors: Hubálek Z,Sixl W,Mikuláskova M,Sixl-Voigt B,Thiel W,Halouzka J,Juricová Z,Rosický B,Mátlová L,Honza M

    更新日期:1995-02-01 00:00:00

  • The molecular regulation of programmed necrotic cell injury.

    abstract::Proper regulation of cell death is essential for metazoan development and functions. Unlike apoptosis, necrosis is a more inflammatory form of cell death that might contribute to antiviral immunity. Indeed, necrotic cell injury is distinguished from apoptosis by extensive organelle and cell swelling and plasma membran...

    journal_title:Trends in biochemical sciences

    pub_type: 杂志文章,评审


    authors: Moquin D,Chan FK

    更新日期:2010-08-01 00:00:00

  • [Neonatal Volkmann's syndrome].

    abstract:BACKGROUND:Acute limb compartment syndrome or Volkmann's ischaemic contracture is an acquired ischaemia of nerve and muscle causes by raised pressure within a closed fascial space. Congenital Volkmann's ischaemic contracture (CVIC) is a rare entity. PATIENTS AND METHODS:A 2-day-old girl was referred with a problem of ...

    journal_title:Annales de dermatologie et de venereologie

    pub_type: 杂志文章


    authors: Dandurand M,Michel B,Fabre C,Stoebner P,Meunier L

    更新日期:2009-11-01 00:00:00

  • [Hepatitis B virus reactivation in rituximab-treated patients: incidence and risk factors].

    abstract::Hepatitis B virus (HBV) reactivation after chemotherapy regimens is a well-known complication. The incidence and risk factors for HBV reactivation remain to be elucidated. We aimed to determine the incidence and risk factors for HBV reactivation in patients receiving rituximab, and the potential role of the cumulative...

    journal_title:Gastroenterologia y hepatologia

    pub_type: 杂志文章


    authors: Gutiérrez García ML,Alonso Lopez S,Martín Rios MD,Sanmartin Fenollera P,Agudo Fernandez S,Fernández Rodriguez CM

    更新日期:2015-01-01 00:00:00

  • Acute kidney injury is associated with higher mortality and healthcare costs in hospitalized patients with cirrhosis.

    abstract:INTRODUCTION AND OBJECTIVES:AKI is known to be associated with increased risk of mortality, however limited information is available on how AKI impacts healthcare costs and resource utilization in hospitalized patients with cirrhosis. Previous studies have had variable definitions of AKI, resulting in inconsistent repo...

    journal_title:Annals of hepatology

    pub_type: 杂志文章,多中心研究


    authors: Karagozian R,Bhardwaj G,Wakefield DB,Verna EC

    更新日期:2019-01-01 00:00:00

  • Grouped circular data in biology: advice for effectively implementing statistical procedures.

    abstract:Abstract:The most common statistical procedure with a sample of circular data is to test the null hypothesis that points are spread uniformly around the circle without a preferred direction. An array of tests for this has been developed. However, these tests were designed for continuously distributed data, whereas ofte...

    journal_title:Behavioral ecology and sociobiology

    pub_type: 杂志文章


    authors: Landler L,Ruxton GD,Malkemper EP

    更新日期:2020-01-01 00:00:00

  • Role of gamma-aminobutyric acid in regulating feed intake in commercial broilers reared under normal and heat stress conditions.

    abstract::This study was conducted to investigate the effects of dietary GABA supplementation on blood biochemical parameters, the overall growth performance, and the relative mRNA expression of some FI- regulating genes in broiler chickens. A total of 192, three-day old chicks of mixed sex from two commercial broiler strains (...

    journal_title:Journal of thermal biology

    pub_type: 杂志文章


    authors: El-Naggar K,El-Kassas S,Abdo SE,Kirrella AAK,Al Wakeel RA

    更新日期:2019-08-01 00:00:00

  • The variations of peroneus digiti quinti muscle and its contribution to the extension of the fifth toe. A cadaveric study.

    abstract:OBJECTIVES:To investigate the origin, prevalence, and possible effects of peroneus digiti quinti muscle (PDQ) on the fifth toe, to find out the variations of PDQ by determining the relationship between peroneus brevis muscle (PB) and PDQ, and to reveal its importance for the applications in foot and ankle surgery.  ME...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Demir BT,Gümüşalan Y,Üzel M,Çevik HB

    更新日期:2015-11-01 00:00:00

  • History of Pick's disease.

    abstract::After a short summary of Arnold Pick's biography, the history of how Pick's disease (PiD) was reported is presented, from its clinical symptoms to its molecular characterization. The macroscopic description of frontotemporal atrophy by Pick is recounted followed by a description of the histological lesions observed by...

    journal_title:Clinical neuropathology

    pub_type: 杂志文章


    authors: Mikol J

    更新日期:2020-07-01 00:00:00

  • Screening for characteristic genes in osteoarthritis induced by destabilization of the medial meniscus utilizing bioinformatics approach.

    abstract:OBJECTIVE:To explore the underlying molecular mechanism of the development of OA (osteoarthritis). METHODS:The expression profile dataset GSE26475 was downloaded from Gene Expression Omnibus database. A total of 21 samples were available, including knee joint samples from OA mice induced by DMM (Destabilization of the...

    journal_title:Journal of musculoskeletal & neuronal interactions

    pub_type: 杂志文章


    authors: Yang X,Zhao J,He Y,Huangfu X

    更新日期:2014-09-01 00:00:00

  • The Anatomy of the Posterior Commissure.

    abstract:AIM:The connections of posterior commissure are defined. Its fibers mediate the consensual light reflex by interconnecting the pretectal nuclei. The fiber connections from the thalamic, pretectal, superior colliculus and the habenular nuclei are known, but they have not been shown anatomically. The present study is a f...

    journal_title:Turkish neurosurgery

    pub_type: 杂志文章


    authors: Ozdemir NG

    更新日期:2015-01-01 00:00:00

  • The status of malaria among pregnant women: a study in Lagos, Nigeria.

    abstract::A study was carried out on the status of malaria among 800 randomly selected pregnant women in Lagos State, Nigeria. Blood samples were obtained from finger pricking and tested for malaria parasites in thin blood films and 60% prevalence of malaria parasites was obtained. Interviews were conducted and structured quest...

    journal_title:African journal of reproductive health

    pub_type: 杂志文章


    authors: Okwa OO

    更新日期:2003-12-01 00:00:00

  • The medical, social, and functional profile of Parkinson's disease patients.

    abstract::The study looked at the medical, social, and functional aspects of 34 patients with idiopathic Parkinson's Disease (PD). Eighty-five percent were above 55 years and 35% were over 70 years. Twenty-four (71%) were males. Most patients had Stage II disease. Overall functional state of the patient correlated closely with ...

    journal_title:Singapore medical journal

    pub_type: 杂志文章


    authors: Lee KS,Merriman A,Owen A,Chew B,Tan TC

    更新日期:1994-06-01 00:00:00

  • Phenotypic and genotypic diversity of airborne fungal spores in Demänovská Ice Cave (Low Tatras, Slovakia).

    abstract::This paper is the first aero-mycological report from Demänovská Ice Cave. Fungal spores were sampled from the internal and external air of the cave in June, 2014, using the impact method with a microbiological air sampler. Airborne fungi cultured on PDA medium were identified using a combination of classical phenotypi...


    pub_type: 杂志文章


    authors: Ogórek R,Kozak B,Višňovská Z,Tančinová D

    更新日期:2018-01-01 00:00:00

  • [Clinical features of systemic sclerosis and association with antitopoisomerase-1 antibody and centromere pattern of antinuclear antibody].

    abstract:OBJECTIVE:To describe clinical features of patients with systemic sclerosis (SSc) and associate them with antitopoisomerase-1 antibody and centromere pattern of antinuclear antibody. METHODS:We evaluated 50 patients who met SSc screening criteria of the American College of Rheumatology, and classified as limited cutan...

    journal_title:Acta reumatologica portuguesa

    pub_type: 杂志文章


    authors: Bertazzi GR,de Toledo RA,de Godoy MF,Geraldino GC,Polizelli DV,Fernandes GC,Pedroso CL,dos Santos FG,de Assis TM

    更新日期:2012-01-01 00:00:00

  • Environmental factors associated with larval habitats of anopheline mosquitoes (Diptera: Culicidae) in irrigation and major drainage areas in the middle course of the Rift Valley, central Ethiopia.

    abstract:BACKGROUND & OBJECTIVES:Larval control is an integral part of malaria vector management in Ethiopia and elsewhere. For effective larval control, a sound understanding of the factors responsible for spatio-temporal variation in larval production is essential. A study was thus conducted to characterize larval habitats of...

    journal_title:Journal of vector borne diseases

    pub_type: 杂志文章


    authors: Kenea O,Balkew M,Gebre-Michael T

    更新日期:2011-06-01 00:00:00