:We present the case of a 79 year-old patient with megaesophagus and aphagia, who required percutaneous endoscopic gastrostomy (PEG) feeding. Megaesophagus was considered the sole cause of aphagia by the referring secondary hospital. Solid state sensor videofluoromanometry (VFM) showed a substantial decrease in manometric values within the hypopharynx along with good relaxation of the upper-esophageal sphincter (UES). This led to electromyography (EMG), which showed features compatible with the diagnosis of Myasthenia Gravis (MG). The diagnosis of MG was confirmed by an intravenous injection of edrophonium chloride, performed under VFM monitoring. The co-existence of MG and megaesophagus rarely occurs in humans; although, most small animals, such as dogs, cats, and rodents, present with megaesophagus as an initial symptom of MG.
authorsDesuter G,Van Parijs V,Gardiner Q
abstract：OBJECTIVE:Parkinson disease (PD) is a debilitating neurodegenerative disease. Caring for an individual with PD can have a variety of negative physical and psychological effects on caregivers which may challenge their ability to continue in their caretaking role. The aim of this study was to assess the prevalence and as...
journal_title：Journal of geriatric psychiatry and neurology
abstract：:To study whether broiler and layer farms contribute to the environmental Campylobacter load, environmental matrices at or close to farms, and caecal material from chickens, were examined. Similarity between Campylobacter from poultry and environment was tested based on species identification and Multilocus Sequence Ty...
journal_title：Journal of water and health
abstract：:A lectin was purified from leaves of Euphorbia helioscopia, by a combination of ion-exchange and gel filtration chromatography. On ion exchange using a DEAE- cellulose column in 0.2 M phosphate buffer, pH 7.2, the bound protein was eluted with a linear sodium chloride gradient of 0.1 M to 0.5 M. Further purification o...
journal_title：Pakistan journal of pharmaceutical sciences
abstract：AIMS:There is still no consensus about the prognostic influence of chronic nephropathy induced by low-dose maintenance therapy with cyclosporin. Our aim was to investigate the prognostic effect of cyclosporin nephropathy in Japanese renal transplant recipients. MATERIAL:We retrospectively investigated the clinical rec...
abstract：INTRODUCTION:Patients requesting body-contouring surgery after massive weight loss often present with abdominal and lumbar skin excess as well as gluteal ptosis and loss of gluteal projection. In order to restore gluteal projection a circular abdominoplasty in combination with an autologous gluteal augmentation (all-in...
journal_title：Acta chirurgica Belgica
abstract：:Obesity poses a serious health hazard and its treatment is often disappointing. Major advances have been made during recent years in the understanding of body weight regulation, with the discovery of leptin, a protein produced by adipocytes and acting on the central nervous system to reduce food intake, and that of be...
journal_title：Acta chirurgica Belgica
abstract：BACKGROUND:The balance between collagenolysis and its inhibition is critical during extracellular matrix remodeling in head and neck squamous cell carcinoma (HNSCC). An imbalance between matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) plays a critical role in the development of tumor cell invasion ...
abstract：:Memory disorders observed in Alzheimer's disease gave rise, from the eighties, to a detailed analysis into the framework of cognitive neuropsychology which aimed at describing the deficits of very specific processes. Beyond their clinical interest, these studies contributed to the modelisation of human memory thanks t...
abstract：:Stem cell transplantation (SCT) has become the therapy of choice for many hematologic and immunologic disorders. At present, only 25% of patients have suitable HLA-identical donors. In an attempt to increase the donor pool for SCT in Thailand and Southeast Asia, we developed a program whereby parents and mismatched si...
journal_title：Asian Pacific journal of allergy and immunology
abstract：:This case report describes a 21-year-old female patient with a complex medical condition of end-stage chronic renal failure and secondary hyperparathyroidism presenting with a history of gradual enlargement of the facial bones over a period of one year. The facial enlargement primarily involves the maxilla causing a b...
journal_title：Saudi medical journal
abstract：:It is a classic story of two related transcription factors. Oct4 is a potent regulator of pluripotency during early mammalian embryonic development, and is notable for its ability to convert adult somatic cells to pluripotency. The widely expressed Oct1 protein shares significant homology with Oct4, binds to the same ...
journal_title：Trends in biochemical sciences
abstract：:Three patients with multiple articular deformities due to arthrogryposis multiplex congenita (AMC) are presented. All had severe thalamic and tegmental degenerations with glial scars and shrunken ferruginated neurons; one had also unilateral porencephaly and polymicrogyri. The character and the pattern of the lesions ...
abstract：:Karyotypes of two bark-lice species Amphipsocus japonicus End. and Dasypsocus japonicus End. (Amphipsocidae, Psocomorpha, Psocoptera) were studied for the first time. D. japonicus displayed 2n = 16 (14 + XX/X0). The XX/X0 sex chromosome system observed in this species is characteristic of the order Psocoptera. A. japo...
abstract：BACKGROUND:Limited information is available on added sugars consumption in US infants and toddlers. OBJECTIVES:To present national estimates of added sugars intake among US infants and toddlers by sociodemographic characteristics, to identify top sources of added sugars, and to examine trends in added sugars intake. ...
journal_title：Journal of the Academy of Nutrition and Dietetics
abstract：:Cloacal swabs, collected from 756 wild synanthropic and exoanthropic birds of 57 species in the Czech Republic, yielded 32 strains of Salmonella typhimurium [phage types (PT) 141, 104 and 41], six isolates of S. enteritidis (PT 8, 4 and 6e), and one each of S. panama and S. anatum. Except for one S. enteritidis isolat...
journal_title：Central European journal of public health
abstract：:Proper regulation of cell death is essential for metazoan development and functions. Unlike apoptosis, necrosis is a more inflammatory form of cell death that might contribute to antiviral immunity. Indeed, necrotic cell injury is distinguished from apoptosis by extensive organelle and cell swelling and plasma membran...
journal_title：Trends in biochemical sciences
abstract：BACKGROUND:Acute limb compartment syndrome or Volkmann's ischaemic contracture is an acquired ischaemia of nerve and muscle causes by raised pressure within a closed fascial space. Congenital Volkmann's ischaemic contracture (CVIC) is a rare entity. PATIENTS AND METHODS:A 2-day-old girl was referred with a problem of ...
journal_title：Annales de dermatologie et de venereologie
abstract：:Hepatitis B virus (HBV) reactivation after chemotherapy regimens is a well-known complication. The incidence and risk factors for HBV reactivation remain to be elucidated. We aimed to determine the incidence and risk factors for HBV reactivation in patients receiving rituximab, and the potential role of the cumulative...
journal_title：Gastroenterologia y hepatologia
abstract：INTRODUCTION AND OBJECTIVES:AKI is known to be associated with increased risk of mortality, however limited information is available on how AKI impacts healthcare costs and resource utilization in hospitalized patients with cirrhosis. Previous studies have had variable definitions of AKI, resulting in inconsistent repo...
journal_title：Annals of hepatology
abstract：Abstract:The most common statistical procedure with a sample of circular data is to test the null hypothesis that points are spread uniformly around the circle without a preferred direction. An array of tests for this has been developed. However, these tests were designed for continuously distributed data, whereas ofte...
journal_title：Behavioral ecology and sociobiology
abstract：:This study was conducted to investigate the effects of dietary GABA supplementation on blood biochemical parameters, the overall growth performance, and the relative mRNA expression of some FI- regulating genes in broiler chickens. A total of 192, three-day old chicks of mixed sex from two commercial broiler strains (...
journal_title：Journal of thermal biology
abstract：OBJECTIVES:To investigate the origin, prevalence, and possible effects of peroneus digiti quinti muscle (PDQ) on the fifth toe, to find out the variations of PDQ by determining the relationship between peroneus brevis muscle (PB) and PDQ, and to reveal its importance for the applications in foot and ankle surgery. ME...
journal_title：Saudi medical journal
abstract：:After a short summary of Arnold Pick's biography, the history of how Pick's disease (PiD) was reported is presented, from its clinical symptoms to its molecular characterization. The macroscopic description of frontotemporal atrophy by Pick is recounted followed by a description of the histological lesions observed by...
abstract：OBJECTIVE:To explore the underlying molecular mechanism of the development of OA (osteoarthritis). METHODS:The expression profile dataset GSE26475 was downloaded from Gene Expression Omnibus database. A total of 21 samples were available, including knee joint samples from OA mice induced by DMM (Destabilization of the...
journal_title：Journal of musculoskeletal & neuronal interactions
abstract：AIM:The connections of posterior commissure are defined. Its fibers mediate the consensual light reflex by interconnecting the pretectal nuclei. The fiber connections from the thalamic, pretectal, superior colliculus and the habenular nuclei are known, but they have not been shown anatomically. The present study is a f...
abstract：:A study was carried out on the status of malaria among 800 randomly selected pregnant women in Lagos State, Nigeria. Blood samples were obtained from finger pricking and tested for malaria parasites in thin blood films and 60% prevalence of malaria parasites was obtained. Interviews were conducted and structured quest...
journal_title：African journal of reproductive health
abstract：:The study looked at the medical, social, and functional aspects of 34 patients with idiopathic Parkinson's Disease (PD). Eighty-five percent were above 55 years and 35% were over 70 years. Twenty-four (71%) were males. Most patients had Stage II disease. Overall functional state of the patient correlated closely with ...
journal_title：Singapore medical journal
abstract：:This paper is the first aero-mycological report from Demänovská Ice Cave. Fungal spores were sampled from the internal and external air of the cave in June, 2014, using the impact method with a microbiological air sampler. Airborne fungi cultured on PDA medium were identified using a combination of classical phenotypi...
abstract：OBJECTIVE:To describe clinical features of patients with systemic sclerosis (SSc) and associate them with antitopoisomerase-1 antibody and centromere pattern of antinuclear antibody. METHODS:We evaluated 50 patients who met SSc screening criteria of the American College of Rheumatology, and classified as limited cutan...
journal_title：Acta reumatologica portuguesa
abstract：BACKGROUND & OBJECTIVES:Larval control is an integral part of malaria vector management in Ethiopia and elsewhere. For effective larval control, a sound understanding of the factors responsible for spatio-temporal variation in larval production is essential. A study was thus conducted to characterize larval habitats of...
journal_title：Journal of vector borne diseases