Enhancing Effect of Intermittent Parathyroid Hormone Administration on Bone Formation After Titanium Implant Placement in an Ovariectomized Rat Maxilla.


OBJECTIVE:This study examined the effect of intermittent parathyroid hormone (PTH) administration on the bone response around implant on the maxilla of rats with ovariectomy-induced osteoporosis. MATERIAL AND METHODS:A total of 27 female Sprague-Dawley rats were divided into 3 groups (n = 9) and were ovariectomized (OVX). Eight weeks after, upper right molar was extracted and an implant was placed at 4 weeks after extraction. The PTH group received PTH, and the OVX group and the control group received vehicle only. Beginning after implant placement, 30 μg/kg of PTH was subcutaneously administered in the dorsum 3 times a week. Three rats in each group were killed at 1, 2, and 4 weeks and histologic sections were evaluated. RESULTS:After 4 weeks, the amount of newly formed bone around implants in the PTH group was comparable with the control group, with bone covering the implant surface in both groups. However, the OVX group displayed relatively small amount of new bone. CONCLUSION:Intermittent PTH has the potential to increase new bone formation around implant. These findings have clinical implications in prosthetic restoration by implants with poor bone quality.


Implant Dent


Implant dentistry


Heo HA,Park SH,Jeon YS,Pyo SW




Has Abstract


2016-04-01 00:00:00












  • Comparison of 3 luting agents on retention of implant-supported crowns on 2 different abutments.

    abstract:BACKGROUND:For fixed prostheses, retention is one of the most important factors for clinical success. It is unknown whether grooves that increase surface area of implant abutment while retaining the diameter and wall height provide greater uniaxial retention force. The purpose of this study was to determine the retenti...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Güncü MB,Cakan U,Canay S

    更新日期:2011-10-01 00:00:00

  • An evaluation of new designs in implant-abutment connections: a finite element method assessment.

    abstract:PURPOSE:This research sought first to evaluate the differences in the finite element method (FEM) analysis of 4 different implant surfaces, including internal and external connections of the same manufacturer with additional modifications. METHODS:In this study, 4 dental implants from the same manufacturer were compar...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Covani U,Ricci M,Tonelli P,Barone A

    更新日期:2013-06-01 00:00:00

  • Flap Designs for Implant-Related Surgical Procedures: A Review.

    abstract:PURPOSE:The objective of this study was to compare the reliability and results of 2 flap techniques, flapless (FL) and full-thickness (FT) flap, during implant placement. MATERIALS AND METHODS:Online and hand searches of the literature published were conducted to identify studies examining different flap techniques on...

    journal_title:Implant dentistry

    pub_type: 杂志文章,评审


    authors: Al-Juboori MJ

    更新日期:2016-12-01 00:00:00

  • Growth of bioactive surfaces on dental implants.

    abstract::Some metallic materials, such as pure titanium, Ti-6Al-4V, are used for dental and orthopedic implants under load-bearing conditions. However, they do not form a chemical bond with bone, which would achieve a good implant-bone fixation in service. In recent works, it has been demonstrated that an in vitro, chemically ...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Manero JM,Salsench J,Nogueras J,Aparicio C,Padrós A,Balcells M,Gil FJ,Planell JA

    更新日期:2002-01-01 00:00:00

  • Le Fort I osteotomy in atrophied maxilla and bone regeneration with pure-phase beta-tricalcium phosphate and PRP.

    abstract::Le Fort I osteotomy is a versatile procedure in oral and maxillofacial surgery for the correction of dysgnathias as well as for an easy approach to the surgical site in neurosurgery; however, it is rarely performed for a vertical advancement of the maxilla. This paper presents the successful use of the synthetic pure-...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Foitzik C,Staus H

    更新日期:2003-01-01 00:00:00

  • Bone quality and the immediate loading of implants-critical aspects based on literature, research, and clinical experience.

    abstract::Immediate loading of oral implants has been extensively described in the international literature and the requirements for long-term success are evaluated. The author presents here the critical aspects of the criteria for success as well as describes the characteristics of an implant macro- and microdesign for immedia...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Romanos GE

    更新日期:2009-06-01 00:00:00

  • Reconstruction and Implant-Supported Rehabilitation of an Iatrogenically Caused Maxillary Alveolar Defect.

    abstract::Defects of the oral and maxillofacial region may arise from several reasons such as trauma, infection, cyst, tumor, medication related osteonecrosis of the jaw, and misuse of some irritant agents. For reconstruction, autogenous grafts remain the gold standard among the alternatives. In our case, a 42-year-old woman re...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Tüz HH,Koç O,Meral SE,El AS

    更新日期:2019-10-01 00:00:00

  • Success Rate of Two-Piece Zirconia Implants: A Retrospective Statistical Analysis.

    abstract:PURPOSE:About 10 years ago, one-piece zirconia implants were introduced to dentistry. The aim of the study was to evaluate the clinical success of two-piece zirconia implants regarding osseointegration using the manufacturers' warranty data. MATERIALS AND METHODS:Over a period of 4 years (2010-2014), the data of warra...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Jank S,Hochgatterer G

    更新日期:2016-04-01 00:00:00

  • Radiographic evaluation of alveolar crest obscured by dental implants.

    abstract::This study evaluated the diagnostic accuracy of periapical, tomographic, and cross-sectional occlusal radiographic techniques in the assessment of facial and lingual bone loss at implant obscured sites. An edentulous dry human mandible was prepared with implants in the incisor, premolar, and molar regions. Successive ...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Ludlow JB,Nason RH Jr,Hutchens LH Jr,Moriarty J

    更新日期:1995-04-01 00:00:00

  • Ridge expansion with acellular dermal matrix and deproteinized bovine bone: a case report.

    abstract::Reduction of the original height and width of the alveolar bone of an edentulous site precludes optimal positioning of implant fixtures and may esthetically compromise the prosthesis. Ridge expansion at the time of extraction can prevent the need for ridge reduction and reduces the number of surgical interventions.A p...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Park JB

    更新日期:2007-09-01 00:00:00

  • In vitro evaluation of horizontal implant micromovement in bone specimen with contact endoscopy.

    abstract::Primary stability of dental implants is mandatory for their osseointegration. A method is described that allows objective measurements of implant displacement in bone sites during lateral loading. Ten samples of bovine bone (2 cm x 2 cm) with bone type II, III, and IV according to Lekholm and Zarb were used for the ex...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Engelke W,Decco OA,Rau MJ,Massoni MC,Schwarzwäller W

    更新日期:2004-03-01 00:00:00

  • Use of narrow-diameter implants in the posterior jaw: a systematic review.

    abstract:STATEMENT OF PROBLEM:Evidence is limited on the efficacy of narrow-diameter implants (NDIs) in the posterior jaw. PURPOSE:The purpose of this systematic review was to assess the survival of NDIs and provide guidelines for their safe use. MATERIALS AND METHODS:Electronic search of the English-language literature enric...

    journal_title:Implant dentistry

    pub_type: 杂志文章,评审


    authors: Assaf A,Saad M,Daas M,Abdallah J,Abdallah R

    更新日期:2015-06-01 00:00:00

  • Doxycycline and Autogenous Bone in Repair of Critical-Size Defects.

    abstract:PURPOSE:The association of doxycycline (DOX) and autogenous bone on repair of critical-size defects was evaluated. MATERIALS AND METHODS:Fifty albino rats were divided into 5 groups (n = 10). A 5-mm diameter defect was treated with: control (CO)-blood clot; DOX in Natrosol (NAT)-10% gel; NAT-gel; particulate autogenou...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Lucateli RL,Marciano MA,Ferreira S,Garcia Júnior IR,Camilleri J,Mariano RC

    更新日期:2018-08-01 00:00:00

  • Periimplant changes in different transplanted soft tissues around loaded endosseous implants in patients after oral tumor surgery.

    abstract:PURPOSE:To examine periimplant reaction of transplanted soft tissues foreign to oral cavity when compared with local gingiva. METHODS:In 58 oral cancer patients, 210 dental implants were inserted mainly in the mandible after radical surgery and reconstruction. Ninety-six implants penetrated transplants (split skin, mu...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Kovács AF,Wallowy P,Stefenelli U,Landau S

    更新日期:2013-12-01 00:00:00

  • Maxillary sinus floor augmentation using bovine bone grafts with simultaneous implant placement: a 5-year prospective follow-up study.

    abstract:PURPOSE:The aim of this study was to evaluate the 5 year clinical results of maxillary sinus floor augmentation using bovine bone grafts with simultaneous implant placement. MATERIAL AND METHODS:A total of 28 patients were enrolled in the study, and a total of 84 implants were placed into the grafted sites. Unilateral...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Özkan Y,Akoğlu B,Kulak-Özkan Y

    更新日期:2011-12-01 00:00:00

  • Guided bone regeneration using nonexpanded polytetrafluoroethylene membranes in preparation for dental implant placements--a report of 420 cases.

    abstract::The biologic principle of guided bone regeneration has been successfully used to prevent bone loss in extraction sites. This study comprises 420 cases of alveolar ridge maintenance in preparation for dental implant placements. Nonexpanded polytetrafluoroethylene membranes were positioned over all extraction sites and ...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Barboza EP,Stutz B,Ferreira VF,Carvalho W

    更新日期:2010-02-01 00:00:00

  • Research of StemBios Cell Therapy on Dental Implants Containing Nanostructured Surfaces: Biomechanical Behaviors, Microstructural Characteristics, and Clinical Trial.

    abstract:PURPOSE:The aim of the present study was to examine the osseointegration in low-density bone tissue for SLAffinity-treated implants with StemBios (SB) cell therapy. MATERIALS AND METHODS:The morphologies of SLAffinity-treated surfaces were characterized using scanning electron microscopy. In the animal model, implants...

    journal_title:Implant dentistry

    pub_type: 临床试验,杂志文章


    authors: Ou KL,Weng CC,Wu CC,Lin YH,Chiang HJ,Yang TS,Wang J,Yen Y,Cheng HY,Sugiatno E

    更新日期:2016-02-01 00:00:00

  • Scanning electron microscope evaluation of vertical and horizontal discrepancy in cast copings for single-tooth implant-supported prostheses.

    abstract:STATEMENT OF PROBLEM:Despite careful attention to waxing, investing, and casting, marginal discrepancies are inevitable. Vertical and horizontal discrepancies can result in crestal bone resorption, peri-implantitis, and loss of osseointegration. PURPOSE:The aim of this study was to evaluate marginal gap and overhang i...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Siadat H,Alikhasi M,Mirfazaelian A,Zade MM

    更新日期:2008-09-01 00:00:00

  • In Vitro Microbiological Analysis of Bacterial Seal in Hybrid Zirconia Abutment Tapered Connection.

    abstract:PURPOSE:The aim of this study was to evaluate the bacterial seal at the implant-hybrid zirconia abutment interface and Morse taper-type connections through in vitro microbiological analysis. MATERIALS AND METHODS:Sixteen implants and their respective abutments were divided into 3 groups: test (10 sets), positive contr...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Harlos MM,Bezerra da Silva T,Peruzzo DC,Napimoga MH,Joly JC,Martinez EF

    更新日期:2017-04-01 00:00:00

  • Private practice results of dental implants. Part I: survival and evaluation of risk factors--Part II: surgical and prosthetic complications.

    abstract::The aim of this study is to present the clinical data from the use of implants that were placed and restored in four independent private dental offices. In part I, the survival rate was calculated and the failure causes were associated with some potential risk factors. In part II, the surgical and prosthetic complicat...

    journal_title:Implant dentistry

    pub_type: 杂志文章,多中心研究


    authors: Kourtis SG,Sotiriadou S,Voliotis S,Challas A

    更新日期:2004-12-01 00:00:00

  • Comparison between unsintered hydroxyapatite/poly-L-lactic acid mesh and titanium mesh in bone regeneration of rabbit mandible.

    abstract:PURPOSE:The purpose of this study was to compare the bone regenerative capability of using unsintered hydroxyapatite/poly-L-lactic acid (uHA/PLLA) mesh and titanium mesh. MATERIALS AND METHODS:Adult male white rabbits (n = 24) were divided into 2 groups. After incising along the mandible, 3 × 5 mm bone defects were ma...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Moroi A,Ueki K,Okabe K,Marukawa K,Sotobori M,Mukozawa A,Miyazakia M

    更新日期:2013-06-01 00:00:00

  • Cancellous and cortical microparticulate allograft for dental implantation: an experimental study in non-human primates.

    abstract:BACKGROUND:: A comparison of freeze-dried cancellous and cortical particulate bone allograft was made using a non-human primate model. METHODS AND MATERIALS:: Microparticulate bone allograft (90-300 μm size) made from either cortical or cancellous bone was used to pack standard bone defects in the lower extremities of...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Malinin T,Temple HT,Garg A

    更新日期:2009-10-01 00:00:00

  • A modified implant healing abutment to optimize soft tissue contours: a case report.

    abstract::The soft tissue profile created around a conventional healing abutment may be inadequate to accommodate an anatomically shaped abutment that is larger than a standard machined abutment. This causes difficulties in its insertion and subsequent impression-making and provisional restoration fabrication. This article pres...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Pow EH,McMillan AS

    更新日期:2004-12-01 00:00:00

  • Dental implants and the geriatric patient.

    abstract::Dental care of the aging patient presents a number of problems not encountered in younger patients. Most of these problems result from tissue changes that occur during aging. Dental implants and implant-retained and/or implant-supported prostheses are viable treatment options for older patients. The majority of elderl...

    journal_title:Implant dentistry

    pub_type: 杂志文章,评审


    authors: Garg AK,Winkler S,Bakaeen LG,Mekayarajjananonth T

    更新日期:1997-10-01 00:00:00

  • A maxillary ridge-splitting technique followed by immediate placement of implants: a case report.

    abstract::Maxillary alveolar atrophy often limits the placement of dental implants. This article reports on a refinement of a technique for widening the atrophic ridge by splitting the alveolar bone longitudinally. Treatment of a patient with a severely resorbed edentulous maxilla is described. Six 4-mm wide by 13-mm long threa...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Calvo Guirado JL,Yuguero MR,Carrión del Valle MJ,Zamora GP

    更新日期:2005-03-01 00:00:00

  • The possible association among bone density values, resonance frequency measurements, tactile sense, and histomorphometric evaluations of dental implant osteotomy sites: a preliminary study.

    abstract:PURPOSE:The aim of the clinical preliminary trial was to determine the possible relationship among radiologic bone density, primary implant stability, and tactile sense measurements, and to clarify their possible association with histological measurements at endosseous implant osteotomy sites. MATERIALS:Eleven mandibu...

    journal_title:Implant dentistry

    pub_type: 临床试验,杂志文章


    authors: Aksoy U,Eratalay K,Tözüm TF

    更新日期:2009-08-01 00:00:00

  • Immediate implant placement without bone grafting: a retrospective study of 110 cases with 5 years of follow-up.

    abstract:PURPOSE:Immediate implant placement not only reduces the number of surgeries necessary but also decreases the treatment time and treatment costs. The purpose of the study was to present the clinical results of 110 cases of immediate implant placement without using graft materials at the end of 5 years. MATERIALS AND M...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Atalay B,Öncü B,Emes Y,Bultan Ö,Aybar B,Yalçin S

    更新日期:2013-08-01 00:00:00

  • Histological and histomorphometric evaluation of anorganic bovine bone used for maxillary sinus floor augmentation: a six-month and five-year follow-up of one clinical case.

    abstract:BACKGROUND:Anorganic bovine bone (ABB) is widely used in maxillary sinus floor augmentation procedures. Nevertheless, long-term human clinical cases data are very rare but still important to understand the behavior of the xenograft. The objective of this study was to analyze and to compare the histological and histomor...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Ohayon L

    更新日期:2014-06-01 00:00:00

  • Natural teeth used as provisionals in immediate implant loading in the maxilla: a case report.

    abstract:PURPOSE:The purpose of this article is to describe a clinical case in which the patient's natural teeth were extracted and used as provisionals immediately after the implants had been placed. PATIENT PRESENTATION:A 52-year-old woman was treated with implants at the 2 maxillary central incisors using osseotite-tapered ...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Miranda ME,Olivieri KA

    更新日期:2012-02-01 00:00:00

  • Influence of patient characteristics on Finnish dentists' decision-making in implant therapy.

    abstract::The purpose of this survey was to evaluate the association of various patient characteristics or possible contraindications with dentists' treatment decisions in oral implantology among general practitioners (GPs) and dental teachers (DTs) in Finland. A questionnaire was mailed to 400 GPs, selected by stratified rando...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Heinikainen M,Vehkalahti M,Murtomaa H

    更新日期:2002-01-01 00:00:00