Enhancing Effect of Intermittent Parathyroid Hormone Administration on Bone Formation After Titanium Implant Placement in an Ovariectomized Rat Maxilla.


OBJECTIVE:This study examined the effect of intermittent parathyroid hormone (PTH) administration on the bone response around implant on the maxilla of rats with ovariectomy-induced osteoporosis. MATERIAL AND METHODS:A total of 27 female Sprague-Dawley rats were divided into 3 groups (n = 9) and were ovariectomized (OVX). Eight weeks after, upper right molar was extracted and an implant was placed at 4 weeks after extraction. The PTH group received PTH, and the OVX group and the control group received vehicle only. Beginning after implant placement, 30 μg/kg of PTH was subcutaneously administered in the dorsum 3 times a week. Three rats in each group were killed at 1, 2, and 4 weeks and histologic sections were evaluated. RESULTS:After 4 weeks, the amount of newly formed bone around implants in the PTH group was comparable with the control group, with bone covering the implant surface in both groups. However, the OVX group displayed relatively small amount of new bone. CONCLUSION:Intermittent PTH has the potential to increase new bone formation around implant. These findings have clinical implications in prosthetic restoration by implants with poor bone quality.


Implant Dent


Implant dentistry


Heo HA,Park SH,Jeon YS,Pyo SW




Has Abstract


2016-04-01 00:00:00












  • Tissue compatibility to different surfaces of dental implants: in vitro studies.

    abstract::Factors affecting cell and tissue responses to dental implant biomaterials are typically characterized as spatial and temporal. Spatially, a dental implant must form an interface with both bone tissue for the development and maintenance of biomechanical stability and soft tissue for the prevention of microbial infecti...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Keller JC

    更新日期:1998-01-01 00:00:00

  • Current status of tissue expanders in alveolar ridge augmentation: a review.

    abstract::The need for major surgery involving bone and skin grafting procedures in the treatment of severe alveolar atrophy has, for many patients, been obviated by the advent of reliable endosseous implant systems. However, some patients, usually for medical, psychological, or financial reasons are unsuitable for endosseous i...

    journal_title:Implant dentistry

    pub_type: 杂志文章,评审


    authors: Quayle AA,McCord JF

    更新日期:1992-10-01 00:00:00

  • Bone quality and the immediate loading of implants-critical aspects based on literature, research, and clinical experience.

    abstract::Immediate loading of oral implants has been extensively described in the international literature and the requirements for long-term success are evaluated. The author presents here the critical aspects of the criteria for success as well as describes the characteristics of an implant macro- and microdesign for immedia...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Romanos GE

    更新日期:2009-06-01 00:00:00

  • Rehabilitation of Postextractive Socket in the Premaxilla: A 12-Year Study on 27 Titanium Plasma Spray Resorbable Calcium Phosphate Coated Single Implants.

    abstract:OBJECTIVES:The purpose of this study was to evaluate the peri-implant bone tissue level on postextractive resorbable calcium phosphate coated single implants placed in premaxillary sites grafted with autologous bone, anorganic bovine bone (ABB), platelet-rich plasma (PRP), and keratinized epithelial connective graft ov...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Perrotti V,Vozza I,Tumedei M,Pompa G,Iaculli F,Quaranta A

    更新日期:2018-08-01 00:00:00

  • Stress and strain patterns of 1-piece and 2-piece implant systems in bone: a 3-dimensional finite element analysis.

    abstract:STATEMENT OF PROBLEM:The transition from implant to abutment is solid in 1-piece (1P) and broken in 2-piece (2P) implant designs. This difference may affect occlusal load distribution and marginal bone response. PURPOSE:To determine whether 1P and 2P implants with equivalent geometries exhibited stresses and strains d...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Ormianer Z,Ben Amar A,Duda M,Marku-Cohen S,Lewinstein I

    更新日期:2012-02-01 00:00:00

  • In-Site Monocyte Implantation in Bone Grafting for Maxillary Atrophy Reconstruction: A Preliminary Observational Proof of Concept Study.

    abstract:PURPOSE:The main objective of this study, involving 11 patients, is to share our experience on an integrated treatment modality, namely, the use of cellular therapy simultaneously with surgical reconstruction. Published works show that the implantation of monocytes in ischemic tissue enhances healing by providing neo-a...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Del Deo V,Fico A,Marini C,Senese S,Gasparini G

    更新日期:2018-10-01 00:00:00

  • Effect of location on primary stability and healing of dental implants.

    abstract:PURPOSE:To study implant primary stability and bone healing using resonance frequency analysis in different anatomical locations 4 months after placement. MATERIAL AND METHODS:Fifty-six partially edentulous patients restored by dental implants were included. Overall, 214 implants were placed without bone or soft tissu...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Monje A,Suarez F,Garaicoa CA,Monje F,Galindo-Moreno P,García-Nogales A,Wang HL

    更新日期:2014-02-01 00:00:00

  • An in vitro investigation concerning the bacterial leakage at implants with internal hexagon and Morse taper implant-abutment connections.

    abstract:PURPOSE:To evaluate, in vitro, the leakage observed in internal hexagon and Morse taper implant-abutment connections. MATERIALS:Ten specimens with internal hexagon and 10 with Cone Morse connection were used. The inner parts of 5 implants, per group, were inoculated with Pseudomonas aeruginosa (PS) suspension and 5 im...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Tripodi D,Vantaggiato G,Scarano A,Perrotti V,Piattelli A,Iezzi G,DʼErcole S

    更新日期:2012-08-01 00:00:00

  • Why do dental implants fail? Part I.

    abstract::Many factors are attributed to failure of the dental implant, either directly or indirectly. The focus of this article is to define the causation of dental implant failure, as well as to present an evaluation of the implant literature regarding etiology, classification, management, and treatment of implant failures. T...

    journal_title:Implant dentistry

    pub_type: 杂志文章,评审


    authors: el Askary AS,Meffert RM,Griffin T

    更新日期:1999-01-01 00:00:00

  • Doxycycline and Autogenous Bone in Repair of Critical-Size Defects.

    abstract:PURPOSE:The association of doxycycline (DOX) and autogenous bone on repair of critical-size defects was evaluated. MATERIALS AND METHODS:Fifty albino rats were divided into 5 groups (n = 10). A 5-mm diameter defect was treated with: control (CO)-blood clot; DOX in Natrosol (NAT)-10% gel; NAT-gel; particulate autogenou...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Lucateli RL,Marciano MA,Ferreira S,Garcia Júnior IR,Camilleri J,Mariano RC

    更新日期:2018-08-01 00:00:00

  • In Vitro Microbiological Analysis of Bacterial Seal in Hybrid Zirconia Abutment Tapered Connection.

    abstract:PURPOSE:The aim of this study was to evaluate the bacterial seal at the implant-hybrid zirconia abutment interface and Morse taper-type connections through in vitro microbiological analysis. MATERIALS AND METHODS:Sixteen implants and their respective abutments were divided into 3 groups: test (10 sets), positive contr...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Harlos MM,Bezerra da Silva T,Peruzzo DC,Napimoga MH,Joly JC,Martinez EF

    更新日期:2017-04-01 00:00:00

  • Investigation of influence of different implant size and placement on stress distribution with 3-dimensional finite element analysis.

    abstract:PURPOSE:The purpose of this study was to analyze the biomechanical behavior of implants with varying number, inclination, and size, using 3-dimensional finite element (FE) analysis. MATERIAL AND METHODS:A total of 10 FE models were constructed to simulate 5 implant placement configurations: 4 and 5 axial implants, 4 i...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Balkaya MC

    更新日期:2014-12-01 00:00:00

  • Evaluation of impression accuracy for implant at various angulations.

    abstract:PURPOSE:The purpose of this study was to compare 2 splinted impression transfer techniques for implant-supported prostheses. MATERIALS:A metal matrix (control) with 4 implants was used. The implants were positioned at 90, 80, 75, and 65 degrees in relation to the surface of the matrix. Squared impression copings were ...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Assunção WG,Britto RC,Ricardo Barão VA,Delben JA,dos Santos PH

    更新日期:2010-04-01 00:00:00

  • Successful Surgical Protocols in the Treatment of Peri-Implantitis: A Narrative Review of the Literature.

    abstract:BACKGROUND:The aim was to identify and evaluate those surgical protocols reporting on positive clinical outcomes for treating peri-implantitis with 12 or more months of follow-up. Method of surface decontamination (SDC) was evaluated for any correlation with outcomes. RESULTS:A literature search was performed of all a...

    journal_title:Implant dentistry

    pub_type: 杂志文章,评审


    authors: Froum SJ,Dagba AS,Shi Y,Perez-Asenjo A,Rosen PS,Wang WC

    更新日期:2016-06-01 00:00:00

  • Heterotopic bone formation around sintered porous-surfaced Ti-6Al-4V implants coated with native bone morphogenetic proteins.

    abstract:PURPOSE:Coating endosseous dental implants with growth factors such as bone morphogenetic proteins (BMPs) may be one way to accelerate and/or enhance the quality of osseointegration. The purpose of this study was to investigate in the murine muscle pouch model whether sintered porous-surfaced titanium alloy implants co...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Simon Z,Deporter DA,Pilliar RM,Clokie CM

    更新日期:2006-09-01 00:00:00

  • Rehabilitation of Full-Mouth Edentulism: Immediate Loading of Implants Inserted With Computer-Guided Flapless Surgery Versus Conventional Dentures: A 5-Year Multicenter Retrospective Analysis and OHIP Questionnaire.

    abstract:OBJECTIVE:The purpose of this report is to compare satisfaction of patients rehabilitated with full-mouth fixed prostheses using computer-aided flapless implant placement and immediate loading with patients rehabilitated with conventional removable prostheses. MATERIALS AND METHODS:The study included 30 consecutive fu...

    journal_title:Implant dentistry

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Marra R,Acocella A,Alessandra R,Ganz SD,Blasi A

    更新日期:2017-02-01 00:00:00

  • The influence of the attachment type and implant number supporting mandibular overdentures on stress distribution: an in vitro study, part I.

    abstract:OBJECTIVES:The main goal of this study was to compare the stress distribution of mandibular overdentures (OVD) with different numbers of supporting implants and single versus splinted attachment types. MATERIALS AND METHODS:Four different biting situations were simulated for the 2-, 3-, and 4-implant retentive anchor ...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Arat Bilhan S,Bilhan H,Bozdag E,Sunbuloglu E,Baykasoglu C,Kutay O

    更新日期:2013-02-01 00:00:00

  • Crestal sinus lift with sequential drills and simultaneous implant placement in sites with

    abstract:PURPOSE:The aim of this multicenter retrospective clinical study was to evaluate the survival rate of implants placed in the posterior maxilla with a residual bone height of <5 mm. MATERIALS AND METHODS:One hundred seventeen patients, recruited from 6 different centers, had 134 implants placed below the maxillary sinu...

    journal_title:Implant dentistry

    pub_type: 杂志文章,多中心研究


    authors: Bernardello F,Righi D,Cosci F,Bozzoli P,Soardi CM,Spinato S

    更新日期:2011-12-01 00:00:00

  • Microstructural and topographical characterization of different surface treatments of a surgical titanium alloy for dental implants.

    abstract:OBJECTIVE:To perform a topographical characterization of a titanium alloy subjected to different surface treatments using roughness evaluation, scanning electron microscopy, and atomic force microscopy. MATERIALS AND METHODS:For each group, 6 discs of a titanium alloy had their surfaces modified by 4 treatments. All s...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Carimo Marino LA,Deliberador TM,Zielak JC,Correr GM,Giovanini AF,Gonzaga CC

    更新日期:2012-06-01 00:00:00

  • Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery: A Systematic Review.

    abstract:OBJECTIVES:The aim of the present study was to review the effectiveness, side effects, and patient acceptance of different concentrations and formulation of chlorhexidine-based mouthwashes used after periodontal and implant surgery. MATERIALS AND METHODS:The PRISMA guideline was adopted in the search strategy using el...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Chye RML,Perrotti V,Piattelli A,Iaculli F,Quaranta A

    更新日期:2019-02-01 00:00:00

  • Factors Influencing the Soft Tissue Changes Around Single Laser Microtextured Implants-Abutments in the Anterior Maxilla: A 5-Year Retrospective Study.

    abstract:PURPOSE:The aim of this study was to evaluate the possible factors that influenced the periimplant soft tissue changes around single implants-abutments with laser-microtextured surface (LMS) in the esthetic zone. MATERIALS AND METHODS:Thirty-nine units, formed by implant-abutment with LMS were studied. Variables possi...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Guarnieri R,Savio L,Bermonds des Ambrois A,Ippoliti S,Zuffetti F,Stefanelli LV,Di Carlo S,Pompa G

    更新日期:2016-12-01 00:00:00

  • Clinical and histologic outcomes after the use of a novel allograft for maxillary sinus augmentation: a case series.

    abstract:PURPOSE:To document the clinical and histologic outcomes of sinus augmentation using a novel allogenic bone substitute as a sole grafting material. MATERIALS:Patients in need of sinus augmentation before implant placement were recruited for this study. Sinus augmentation procedures were performed following a lateral a...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Avila G,Neiva R,Misch CE,Galindo-Moreno P,Benavides E,Rudek I,Wang HL

    更新日期:2010-08-01 00:00:00

  • Failure of Osseointegrated Dental Implant After Alveolar Nerve Transposition: A Report of an Unusual Complication and Surgical Management.

    abstract:PURPOSE:To describe an unusual case of mandibular fracture after osseointegrated dental implant removal placed after inferior alveolar nerve transposition. REPORT OF CASE:The patient underwent inferior nerve transposition for implant placement due to lack of interarch space. Two months after metal-ceramic crowns insta...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: da Costa Ribeiro R,Barbosa Luna AH,Sverzut CE,Sverzut AT

    更新日期:2017-08-01 00:00:00

  • Implant-retained removable prosthesis with ball attachments in partially edentulous maxilla.

    abstract::This clinical report presents a restorative option for the partially edentulous maxilla utilizing an implant-retained removable partial denture without retentive clasps. This approach required (1) fewer patient visits and laboratory procedures; (2) the use of minimal number of implants; (3) lower financial obligations...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: de Carvalho WR,Barboza EP,Caúla AL

    更新日期:2001-01-01 00:00:00

  • Dental implants osteogenic properties evaluated by cDNA microarrays.

    abstract:OBJECTIVE:This study aims at applying cDNA microarray analysis in vitro for establishing and comparing the osteogenic properties of dental implants with different surface characteristics. MATERIALS AND METHODS:Saos-2 osteoblasts were cultured in bottom-cone tubes in presence of 5 different dental implants with various...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Baldi D,Longobardi M,Cartiglia C,La Maestra S,Pulliero A,Bonica P,Micale RT,Menini M,Pera P,Izzotti A

    更新日期:2011-08-01 00:00:00

  • Evaluation of centrifuged bone marrow on bone regeneration around implants in rabbit tibia.

    abstract:OBJECTIVE:To evaluate the bone regeneration of cervical defects produced around titanium implants filled with blood clot and filled with centrifuged bone marrow (CBM) by means of histomorphometric analysis. MATERIALS AND METHODS:Twelve rabbits received 2 titanium implants in each right tibia, with the upper cortical p...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Betoni W Jr,Queiroz TP,Luvizuto ER,Valentini-Neto R,Garcia-Júnior IR,Bernabé PF

    更新日期:2012-12-01 00:00:00

  • Mandibular fracture as a complication of inferior alveolar nerve transposition and placement of endosseous implants: a case report.

    abstract::Placement of endosseous implants and inferior alveolar nerve transposition is a treatment option for patients with an edentulous posterior mandible with inadequate bone height superior to the inferior alveolar canal. Complications associated with these procedures include infection, prolonged neurosensory disturbances,...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Karlis V,Bae RD,Glickman RS

    更新日期:2003-01-01 00:00:00

  • A six-year follow-up of full-arch immediate restorations fabricated with an intraoral welding technique.

    abstract:PURPOSE:The aim of this study was to evaluate the 6-year effectiveness of maxillary and mandibular full-arch immediately loaded prostheses fabricated using an intraoral welding technique. METHODS:All patients received the same day of surgery a fixed, full-arch prosthesis supported by an intraorally welded titanium fra...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Degidi M,Nardi D,Piattelli A

    更新日期:2013-06-01 00:00:00

  • Effects of Implant Angulation and Impression Coping Type on the Dimensional Accuracy of Impressions.

    abstract:PURPOSE:To analyze the accuracy of impressions in relation to implant angulation and type of impression coping. MATERIALS AND METHODS:Three metal master models with 2 implants of 3 different angulations (parallel, mesiodistal, and buccolingual) were fabricated. Nine groups of experimental models were fabricated to dup...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Shim JS,Ryu JJ,Shin SW,Lee JY

    更新日期:2015-12-01 00:00:00

  • Ridge expansion with acellular dermal matrix and deproteinized bovine bone: a case report.

    abstract::Reduction of the original height and width of the alveolar bone of an edentulous site precludes optimal positioning of implant fixtures and may esthetically compromise the prosthesis. Ridge expansion at the time of extraction can prevent the need for ridge reduction and reduces the number of surgical interventions.A p...

    journal_title:Implant dentistry

    pub_type: 杂志文章


    authors: Park JB

    更新日期:2007-09-01 00:00:00