Abstract:
:The objective of this study was to conduct an incremental cost-effectiveness analysis from the payer's perspective in Singapore of 3 gestational diabetes mellitus screening strategies: universal, targeted, or no screening. A decision tree model assessed the primary outcome: incremental cost per quality-adjusted life year (QALY) gained. Probabilities, costs, and utilities were derived from the literature, the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study, and the KK Women's and Children's Hospital's database. Relative to targeted screening using risk factors, universal screening generates an incremental cost-effectiveness ratio (ICER) of $USD10,630/QALY gained. Sensitivity analyses show that disease prevalence rates and intervention effectiveness of glycemic management have the biggest impacts on the ICERs. Based on the model and best available data, universal screening is a cost-effective approach for reducing the complications of gestational diabetes mellitus in Singapore as compared with the targeted screening approach or no screening.
journal_name
Asia Pac J Public Healthjournal_title
Asia-Pacific journal of public healthauthors
Chen PY,Finkelstein EA,Ng MJ,Yap F,Yeo GS,Rajadurai VS,Chong YS,Gluckman PD,Saw SM,Kwek KY,Tan KHdoi
10.1177/1010539515612908subject
Has Abstractpub_date
2016-01-01 00:00:00pages
15-25issue
1eissn
1010-5395issn
1941-2479pii
1010539515612908journal_volume
28pub_type
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