Incremental Cost-Effectiveness Analysis of Gestational Diabetes Mellitus Screening Strategies in Singapore.

Abstract:

:The objective of this study was to conduct an incremental cost-effectiveness analysis from the payer's perspective in Singapore of 3 gestational diabetes mellitus screening strategies: universal, targeted, or no screening. A decision tree model assessed the primary outcome: incremental cost per quality-adjusted life year (QALY) gained. Probabilities, costs, and utilities were derived from the literature, the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study, and the KK Women's and Children's Hospital's database. Relative to targeted screening using risk factors, universal screening generates an incremental cost-effectiveness ratio (ICER) of $USD10,630/QALY gained. Sensitivity analyses show that disease prevalence rates and intervention effectiveness of glycemic management have the biggest impacts on the ICERs. Based on the model and best available data, universal screening is a cost-effective approach for reducing the complications of gestational diabetes mellitus in Singapore as compared with the targeted screening approach or no screening.

authors

Chen PY,Finkelstein EA,Ng MJ,Yap F,Yeo GS,Rajadurai VS,Chong YS,Gluckman PD,Saw SM,Kwek KY,Tan KH

doi

10.1177/1010539515612908

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

15-25

issue

1

eissn

1010-5395

issn

1941-2479

pii

1010539515612908

journal_volume

28

pub_type

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