Abstract:
:This study was designed to evaluate the cytotoxicity of four dentin bonding agents and the effects of an antioxidant addition. Group A: G-aenial Bond, Group B: Optibond All in One, Group C: Gluma Self Etch and Group D: Clearfil S(3) Bond were added to the medium using extract method. The cells were cultured with or without resveratrol (RES) addition. MTT, reactive oxygen species (ROS), DCF, Comet and 8-OHdG measurements were performed. The agents had a dose-dependent (1:1>1:10>1:20) cytotoxic effect. Considering 1:10 concentration; Group D at 1 h (p<0.01) and Group B and D at 24 h had the weakest cytotoxic effect (p<0.05). After RES addition, the highest cell viability was determined in Groups B+RES and D+RES at 1 h and in Groups A+RES and B+RES at 24 h (p<0.01). The dentin bonding agents induced ROS production and DNA damage regarding to their composition. However, RES addition decreased the indicated parameters.
journal_name
Dent Mater Jjournal_title
Dental materials journalauthors
Atalayin C,Armagan G,Konyalioglu S,Kemaloglu H,Tezel H,Ergucu Z,Keser A,Dagci T,Onal Bdoi
10.4012/dmj.2015-079subject
Has Abstractpub_date
2015-01-01 00:00:00pages
766-73issue
6eissn
0287-4547issn
1881-1361journal_volume
34pub_type
杂志文章abstract::The behavior of microencapsulated polymerization initiators in dental adhesives is unknown. This study investigated the effects of new microencapsulated initiators in novel, multi-purpose, PMMA-type adhesive resin on the bonding performance and polymerization reactivity. Microencapsulated BPO and 1,3,5-trimethylbarbit...
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